Dietary supplementation with β-glucan enriched oat bran increases faecal concentration of carboxylic acids in healthy subjects

European Journal of Clinical Nutrition

Volumn 62, Issue 8, 2008, Pages 978-984

  Nilsson, U ^a   Johansson, M ^a   Nilsson, A ^a   Bjorck I ^a   Nyman, M ^a  

^a LUND UNIVERSITY   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

ACETIC ACID; BETA GLUCAN; BUTYRIC ACID; CARBOXYLIC ACID; ISOBUTYRIC ACID; ISOVALERIC ACID; LACTIC ACID; PROPIONIC ACID;

ADULT; ARTICLE; BRAN; BREAD; DIET SUPPLEMENTATION; DIETARY FIBER; FECES ANALYSIS; FECES LEVEL; FEMALE; HUMAN; HUMAN EXPERIMENT; MALE; NORMAL HUMAN; NUTRIENT CONCENTRATION; OAT;

ADULT; AVENA SATIVA; BETA-GLUCANS; CARBOXYLIC ACIDS; DIETARY FIBER; FECES; FEMALE; FOOD, FORTIFIED; HUMANS; MALE; MIDDLE AGED; YOUNG ADULT;

EID: 49349084076     PISSN: 09543007     EISSN: 14765640     Source Type: Journal    
DOI: 10.1038/sj.ejcn.1602816     Document Type: Article

References (43)

1. Berggren AM, Björck IME, Nyman EMGL, Eggum BO (1993). Short-chain fatty-acid content and pH in cecum of rats given various sources of carbohydrates. J Sci Food Agric 63, 397-406.
2. Bird AR, Hayakawa T, Marsono Y, Gooden JM, Record IR, Correll RL et al. (2000). Coarse brown rice increases fecal and large bowel short-chain fatty acids and starch but lowers calcium in the large bowel of pigs. J Nutr 130, 1780-1787.
3. Bourriaud C, Robins RJ, Martin L, Kozlowski F, Tenailleau E, Cherbut C et al. (2005). Lactate is mainly fermented to butyrate by human intestinal microfloras but inter-individual variation is evident. J Appl Microbiol 99, 201-212.
4. Brown I, Warhurst M, Arcot J, Playne M, Illman RJ, Topping DL (1997). Fecal numbers of bifidobacteria are higher in pigs fed Bifidobacterium longum with a high amylose cornstarch than with a low amylose cornstarch. J Nutr 127, 1822-1827.
5. Bullock NR, Booth JC, Gibson GR (2004). Comparative composition of bacteria in the human intestinal microflora during remission and active ulcerative colitis. Curr Issues Infest Microbiol 5, 59-64.
6. Casterline JL, Oles CJ, Ku Y (1997). In vitro fermentation of various food fiber fractions. J Agric Food Chem 45, 2463-2467.
7. Chapman MA, Grahn MF, Boyle MA, Hutton M, Rogers J, Williams NS (1994). Butyrate oxidation is impaired in the colonic mucosa of sufferers of quiescent ulcerative colitis. Gut 35, 73-76.
8. Cummings J (1995). The Large Intestine in Nutrition and Disease. Institut Danone: Bruxelles.
9. Cummings JH (1997). Short-chain fatty acid enemas in the treatment of distal ulcerative colitis. Eur J Gastroenterol Hepatol 9, 149-153.
10. Den Hond E, Hiele M, Evenepoel P, Peeters M, Ghoos Y, Rutgeerts P (1998). In vivo butyrate metabolism and colonic permeability in extensive ulcerative colitis. Gastroenterology 115, 584-590.
11. Di Sabatino A, Morera R, Ciccocioppo R, Cazzola P, Gotti S, Tinozzi FP et al. (2005). Oral butyrate for mildly to moderately active Crohn's disease. Aliment Pharmacol Ther 22, 789-794.
12. Djouzi Z, Andrieux C (1997). Compared effects of three oligosaccharides on metabolism of intestinal microflora in rats inoculated with a human faecal flora. Br J Nutr 78, 313-324.
13. Galvez J, Rodriguez-Cabezas ME, Zarzuelo A (2005). Effects of dietary fiber on inflammatory bowel disease. Mol Nutr Food Res 49, 601-608.
14. Hallert C, Björck I, Nyman M, Pousette A, Granno C, Svensson H (2003). Increasing fecal butyrate in ulcerative colitis patients by diet: Controlled pilot study. Inflamm Bowel Dis 9, 116-121.
15. Hanauer SB (2004). Update on the etiology; pathogenesis and diagnosis of ulcerative colitis. Nat Clin Prod Gastroenterol Hepatol 1, 26-31.
16. Henningsson AM, Björck IM, Nyman EM (2002). Combinations of indigestible carbohydrates affect short-chain fatty acid formation in the hindgut of rats. J Nutr 132, 3098-3104.
17. Henningsson AM, Nyman MEGL, Björck IM (2003). Influences of dietary adaptation and source of resistant starch on short-chain fatty acids in the hindgut of rats. Br J Nutr 89, 319-328.
18. Jenkins DJ, Kendall CW, Popovich DG, Vidgen E, Mehling CC, Vuksan V et al. (2001). Effect of a very-high-fiber vegetable, fruit, and nut diet on serum lipids and colonic function. Metabolism 50, 494-503.
19. Karppinen S, Liukkonen K, Aura AM, Forssell P, Poutanen K (2000). In vitro fermentation of polysaccharides of rye, wheat and oat brans and inulin by human faecal bacteria. J Sci Food Agric 80, 1469-1476.
20. Lambo-Fodje AM, Öste R, Nyman ME (2006). Short-chain fatty acid formation in the hindgut of rats fed native and fermented oat fibre concentrates. Br J Nutr 96, 47-55.
21. Luhrs H, Gerke T, Muller JG, Melcher R, Schauber J, Boxberge F et al. (2002). Butyrate inhibits NF-kappaB activation in lamina propria macrophages of patients with ulcerative colitis. Scand J Gastroenterol 37, 458-466.
22. Macfarlane GT, Cummings JH (1991). The colonic flora, fermentation, and large bowel digestive function. In: Phillips SF (ed). The Large Intestine: Physiology, Pathophysiology, and Disease. Raven Press, Ltd.: Pp 51-92.
23. McCleary BV, Codd R (1991). Measurement of (1-3),(1-4)-heta-D-glucan in barley and oats - a streamlined enzymatic procedure. J Sci Food Agric 55, 303-312.
24. McIntyre A, Gibson PR, Young GP (1993). Butyrate production from dietary fibre and protection against large bowel cancer in a rat model. Gut 34, 386-391.
25. Menzel T, Luhrs H, Zirlik S, Schauber J, Kudlich T, Gerke T et al. (2004). Butyrate inhibits leukocyte adhesion to endothelial cells via modulation of VCAM-1. Inflamm Bowel Dis 10, 122-128.
26. Nilsson U, Nyman M (2005). Short-chain fatty acid formation in the hindgut of rats fed oligosaccharides varying in monomeric composition, degree of polymerisation and solubility. Br J Nutr 94, 705-713.
27. Nilsson U, Nyman M, Ahrne S, Sullivan EO, Fitzgerald G (2006). Bifidobacterium lactis Bb-12 and Lactobacillus salivarius UCC500 modify carboxylic acid formation in the hindgut of rats given pectin, inulin, and lactitol. J Nutr 136, 2175-2180.
28. Pryde SE, Duncan SH, Hold GL, Stewart CS, Flint HJ (2002). The microbiology of butyrate formation in the human colon. FEMS Microbiol Lett 217, 133-139.
29. Reddy BS, Hirose Y, Cohen LA, Simi B, Cooma I, Rao CV (2000). Preventive potential of wheat bran fractions against experimental colon carcinogenesis: Implications for human colon cancer prevention. Cancer Res 60, 4792-4797.
30. Richardson AJ, Calder AG, Stewart CS, Smith A (1989). Simultaneous determination of volatile and non-volatile acidic fermentation products of anaerobes by capillary gas-chromatography. Lett Appl Microbiol 9, 5-8.
31. Roland N, Nugon-Baudon L, Andrieux C, Szylit O (1995). Comparative study of the fermentative characteristics of inulin and different types of fibre in rats inoculated with a human whole faecal flora. Br J Nutr 74, 239-249.
32. Scheppach W (1996). Treatment of distal ulcerative colitis with short-chain fatty acid enemas. A placebo-controlled trial. German-Austrian SCFA Study Group. Dig Dis Sci 41, 2254-2259.
33. Scheppach W, Bartram HP, Richter F (1995). Role of short-chain fatty acids in the prevention of colorectal cancer. Eur J Cancer 31A 1077-1080.
34. Scheppach W, Sommer H, Kirchner T, Paganelli GM, Bartram P, Christl S et al. (1992). Effect of butyrate enemas on the colonic mucosa in distal ulcerative colitis. Gastroenterology 103, 51-56.
35. Simpson EJ, Chapman MA, Dawson J, Berry D, Macdonald IA, Cole A (2000). In vivo measurement of colonic butyrate metabolism in patients with quiescent ulcerative colitis. Gut 46, 73-77.
36. Smith JG, Yokoyama WH, German JB (1998). Butyric acid from the diet: actions at the level of gene expression. Crit Rev Food Sci Nutr 38, 259-297.
37. Soergel KH, Harig JM, Loo FD, Ramaswamy K, Wood CM (1989). Colonic fermentation and absorption of SCFA in man. Acta Vet Scand Suppl 86, 107-115.
38. Steinhart AH, Hiruki T, Brzezinski A, Baker JP (1996). Treatment of left-sided ulcerative colitis with butyrate enemas: A controlled trial. Aliment Pharmacol Ther 10, 729-736.
39. Vernia P, Annese V, Bresci G, d'Albasio G, D'Inca R, Giaccari S et al. (2003). Topical butyrate improves efficacy of 5-ASA in refractory distal ulcerative colitis: Results of a multicentre trial. Eur J Clin Invest 33, 244-248.
40. Vernia P, Caprilli R, Latella G, Barbetti F, Magliocca FM, Cittadini M (1988). Fecal lactate and ulcerative colitis. Gastroenterology 95, 1564-1568.
41. Wang JM, de Souza R, Kendall CW, Emam A, Jenkins DJ (2006). Colonic health: Fermentation and short chain fatty acids. J Clin Gastroenterol 40, 235-243.
42. Wood PJ (2004). Relationships between solution properties of cereal beta-glucans and physiological effects - a review. Trends Food Sci Technol 15, 313-320.
43. Zoran DL, Turner ND, Taddeo SS, Chapkin RS, Lupton JR (1997). Wheat bran diet reduces tumor incidence in a rat model of colon cancer independent of effects on distal luminal butyrate concentrations. J Nutr 127, 2217-2225.