Combinations of indigestible carbohydrates affect short-chain fatty acid formation in the hindgut of rats

Journal of Nutrition

Volumn 132, Issue 10, 2002, Pages 3098-3104

  Henningsson, Åsa M ^a   Björck, Inger M E ^a   Nyman, E Margareta G L ^a  

^a LUND UNIVERSITY   (Sweden)

Author keywords

Dietary fiber; Fermentation; Rats; Resistant starch; Short chain fatty acids

Indexed keywords

ACETIC ACID; AMYLOSE; BUTYRIC ACID; CARBOHYDRATE; GUAR GUM; PECTIN; PROPIONIC ACID; SHORT CHAIN FATTY ACID; STARCH;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARBOHYDRATE DIET; CHEMICAL COMPOSITION; COLON MUCOSA; CONTROLLED STUDY; DIETARY FIBER; FECES; FERMENTATION; FOOD INTAKE; INTESTINE; INTESTINE TRANSIT TIME; MALE; NONHUMAN; RAT; STATISTICAL ANALYSIS;

ANIMALIA; CYAMOPSIS TETRAGONOLOBA; TRITICUM AESTIVUM;

EID: 0036792197     PISSN: 00223166     EISSN: None     Source Type: Journal    
DOI: 10.1093/jn/131.10.3098     Document Type: Article

References (53)

1. Cummings, J. H. & Macfarlane, G. T. (1991) The control and consequences of bacterial fermentation in the human colon, J. Appl. Bacteriol. 70: 443-459.
2. Scheppach, W. (1994) Effects of short chain fatty acids on gut morphology and function. Gut 35: S35-S38.
3. Ruppin, H., Bar-Meir, S., Soergel, K. H., Wood, C. M. & Schmitt, M. G., Jr, (1980) Absorption of short-chain fatty acids by the colon. Gastroenterology 78: 1500-1507.
4. Roediger, W. E. (1982) Utilization of nutrients by isolated epithelial cells of the rat colon. Gastroenterology 83: 424-429.
5. Clausen, M. R. & Mortensen, P. B. (1994) Kinetic studies on the metabolism of short-chain fatty acids and glucose by isolated rat colonocytes. Gastroenterology 106: 423-432.
6. Scheppach, W., Bartram, H. P. & Richter, F, (1995) Role of short-chain fatty acids in the prevention of colorectal cancer. Eur. J. Cancer 31A: 1077-1080.
7. Mortensen, P, B. & Clausen, M. R. (1996) Short-chain fatty acids in the human colon: relation to gastrointestinal health and disease. Scand. J. Gastroenterol. Suppl. 216: 132-148.
8. Heerdt, B. G., Houston, M. A. & Augenlicht, L. H. (1994) Potentiation by specific short-chain fatty acids of differentiation and apoptosis in human colonic carcinoma cell lines. Cancer Res. 54: 3288-3293.
9. Hague, A. & Paraskeva, C. (1995) The short-chain fatty acid butyrate induces apoptosis in colorectal tumour cell lines. Eur. J. Cancer Prev. 4: 359-364.
10. Weaver, G. A., Krause, J. A., Miller, T. L. & Wolin, M. J. (1988) Short chain fatty acid distributions of enema samples from a sigmoidoscopy population: an association of high acetate and low butyrate ratios with adenomatous polyps and colon cancer. Gut 29: 1539-1543.
11. Wright, R. S., Anderson, J. W. & Bridges, S. R. (1990) Propionate inhibits hepatocyte lipid synthesis. Proc. Soc. Exp. Biol. Med. 195: 26-29.
12. Bugaut, M. & Bentejac, M. (1993) Biological effects of short-chain fatty acids in nonruminant mammals. Annu. Rev. Nutr. 13: 217-241.
13. Berggren, A. M., Björck, I. M., Nyman, E. M. & Eggum, B. O. (1993) Short-chain fatty acid content and pH in caecum of rats given various sources of carbohydrates. J. Sci. Food Agric. 63: 397-406.
14. Brighenti, F., Testolin, G., Canzi, E., Ferrari, A., Wolever, T.M.S., Ciappellano, S., Porrini, M. & Simonetti, P. (1989) Influence of long-term feeding of different purified dietary fibers on the volatile fatty acid (VFA) profile, pH and fiber-degrading activity of the cecal contents in rats. Nutr. Res. 9: 761-772.
15. De Schrijver, R., Vanhof, K. & Vande Ginste, J. (1999) Effect of enzyme resistant starch on large bowel fermentation in rats and pigs. Nutr. Res. 19: 927-936.
16. Morita, T., Kasaoka, S., Hase, K. & Kiriyama, S, (1999) Psyllium shifts the fermentation site of high-amylose cornstarch toward the distal colon and increases fecal butyrate concentration in rats. J. Nutr. 129: 2081-2087.
17. Nyman, M. & Asp, N. G. (1982) Fermentation of dietary fibre components in the rat intestinal tract. Br. J. Nutr. 47: 357-366.
18. Nordgaard, I., Mortensen, P. B. & Langkilde, A. M. (1995) Small intestinal malabsorption and colonic fermentation of resistant starch and resistant peptides to short-chain fatty acids. Nutrition 11: 129-137.
19. Van Soest, P. J. (1995) Comparative aspects of animal models. In: Dietary Fiber in Health and Disease (Kritchevsky, D. & Bonfield, C., eds.), pp. 321-339. Eagan Press, St. Paul, MN.
20. Cummings, J. H, & Englyst, H. N. (1987) Fermentation in the human large intestine and the available substrates. Am. J. Clin. Nutr. 45: 1243-1255.
21. Bufill, J. A. (1990) Colorectal cancer: evidence for distinct genetic categories based on proximal or distal tumor location. Ann. Intern. Med. 113: 779-788.
22. Holt, P. R., Mokuolu, A. O., Distler, P., Liu, T. & Reddy, B. S. (1996) Regional distribution of carcinogen-induced colonic neoplasia in the rat. Nutr. Cancer 25: 129-135.
23. Topping, D. L., Illman, R. J. & Trimble, R. P. (1985) Volatile fatty acid concentrations in rats fed diets containing gum arabic and cellulose separately and as a mixture. Nutr. Rep. Int. 32: 809-814.
24. Karppinen, S., Liukkonen, K., Aura, A.-M., Forssell, P. & Poutanen, K. (2000) In vitro fermentation of polysaccharides of rye, wheat and oat brans and inulin by human faecal bacteria. J. Sci. Food Agric, 80: 1469-1476.
25. McBurney, M. I. & Thompson, L. U. (1989) Effect of human faecal donor on in vitro fermentation variables. Scand. J. Gastroenterol. 24: 359-367.
26. Asp, N.-G., Johansson, C. G., Hallmer, H. & Siljeström, M, (1983) Rapid enzymatic assay of insoluble and soluble dietary fiber. J. Agric. Food Chem. 31: 476-482.
27. Theander, O., Åman, P., Westerlund, E., Andersson, R. & Pettersson, D. (1995) Total dietary fiber determined as neutral sugar residues, uronic acid residues, and Klason lignin (the Uppsala method): collaborative study. J. Assoc. Off. Anal. Chem. Int. 78: 1030-1044.
28. Åkerberg, A. K., Liljeberg, H. G., Granfeldt, Y. E., Drews, A. W. & Björck, I. M. (1998) An in vitro method, based on chewing, to predict resistant starch content in foods allows parallel determination of potentially available starch and dietary fiber. J. Nutr. 128: 651-660.
29. Björck, I.M.E. & Siljeström, M. A. (1992) In-vivo and in-vitro digestibility of starch in autoclaved pea and potato products. J. Sci. Food Agric. 58: 541-553.
30. Richardson, A. J., Calder, A. G., Stewart, C. S. & Smith, A. (1989) Simultaneous determination of volatile and non-volatile acidic fermentation products of anaerobes by capillary gas chromatography. Lett. Appl. Microbiol. 9: 5-8.
31. Minitab. (1997) Minitab Users Guide, Version 12.2. Minitab Inc., State College, PA.
32. Nyman, M. & Asp, N. G. (1985) Dietary fibre fermentation in the rat intestinal tract: effect of adaptation period, protein and fibre levels, and particle size. Br. J. Nutr. 54: 635-643.
33. Brunsgaard, G., Bach Knudsen, K. E. & Eggum, B. O. (1995) The influence of the period of adaptation on the digestibility of diets containing different types of indigestible polysaccharides in rats. Br. J. Nutr. 74: 833-848.
34. Levrat, M. A., Behr, S. R., Rémésy, C. & Demigné, C. (1991) Effects of soybean fiber on cecal digestion in rats previously adapted to a fiber-free diet. J. Nutr. 121: 672-678.
35. Tulung, B., Rémésy, C. & Demigné, C. (1987) Specific effect of guar gum or gum arabic on adaptation of cecal digestion to high fiber diets in the rat. J. Nutr. 117: 1556-1561.
36. Englyst, H. N., Hay, S. & Macfarlane, G. T. (1987) Polysaccharide breakdown by mixed population populations of human faecal bacteria. FEMS Microbiol. Ecol. 45: 163-171.
37. Bradburn, D. M., Mathers, J. C., Gunn, A., Burn, J., Chapman, P. D. & Johnston, I. D. (1993) Colonic fermentation of complex carbohydrates in patients with familial adenomatous polyposis. Gut 34: 630-636.
38. Casterline, J.L.J., Oles, C. J. & Ku, Y. (1997) In vitro fermentation of various food fiber fractions. J. Agric. Food Chem. 45: 2463-2467.
39. Ferguson, L. R., Tasman-Jones, C., Englyst, H. & Harris, P. J. (2000) Comparative effects of three resistant starch preparations on transit time and short-chain fatty acid production in rats. Nutr. Cancer 36: 230-237.
40. de Deckere, E. A., Kloots, W. J. & van Amelsvoort, J. M. (1995) Both raw and retrograded starch decrease serum triacylglycerol concentration and fat accretion in the rat. Br. J. Nutr. 73: 287-298.
41. Andrieux, C., Pacheco, E. D., Bouchet, B., Gallant, D. & Szylit, O. (1992) Contribution of the digestive tract microflora to amylomaize starch degradation in the rat. Br. J. Nutr. 67: 489-499.
42. Lopez, H. W., Levrat-Verny, M. A., Coudray, C., Besson, C., Krespine, V., Messager, A., Demigné, C. & Rémésy, C. (2001) Class 2 resistant starches lower plasma and liver lipids and improve mineral retention in rats. J. Nutr. 131: 1283-1289.
43. Annison, G. & Topping, D. L. (1994) Nutritional role of resistant starch: chemical structure vs physiological function. Annu. Rev. Nutr. 14: 297-320.
44. Le Blay, G., Michel, C., Blottiere, H. M. & Cherbut, C. (1999) Enhancement of butyrate production in the rat caecocolonic tract by long-term ingestion of resistant potato starch. Br. J. Nutr. 82: 419-426.
45. Macfarlane, G. T. & Cummings, J. H. (1995) Microbiological aspects of the production of short-chain fatty acids in the large bowel. In: Physiological Aspects of Short Chain Fatty Acids (Cummings, J.H. Rombeau, J.L. & Sakata, T., eds.), pp. 87-105. Cambridge University Press, Cambridge, UK.
46. Gibson, G. R., Cummings, J. H., Macfarlane, G. T., Allison, C., Segal, I., Vorster, H. H. & Walker, A. R. (1990) Alternative pathways for hydrogen disposal during fermentation in the human colon. Gut 31: 679-683.
47. Bernalier, A., Dore, J. & Durand, M. (1999) Biochemistry of fermentation. In: Colonic Microbiota, Nutrition and Health (Gibson, G.R. & Roberfroid, M. B., eds.), pp. 37-54. Kluwer Academic Publishers, Dordrecht, the Netherlands.
48. Rowland, I. R. (1992) Metabolic interactions in the gut. In: Probiotics. The Scientific Basis (Fuller, R., ed.), Chapman & Hall, London, UK.
49. Mathers, J. C. & Dawson, L. D. (1991) Large bowel fermentation in rats eating processed potatoes. Br. J. Nutr. 66: 313-329.
50. Oufir, L. E., Barry, J. L., Flourie, B., Cherbut, C., Cloarec, D., Bornet, F. & Galmiche, J. P. (2000) Relationships between transit time in man and in vitro fermentation of dietary fiber by fecal bacteria. Eur. J. Clin. Nutr. 54: 603-609.
51. De Schrijver, R., Vanhof, K. & Vande Ginste, J. (1999) Nutrient utilization in rats and pigs fed enzyme resistant starch. Nutr. Res. 19: 1349-1361.
52. Govers, M. J., Gannon, N. J., Dunshea, F. R., Gibson, P. R. & Muir, J. G. (1999) Wheat bran affects the site of fermentation of resistant starch and luminal indexes related to colon cancer risk: a study in pigs. Gut 45: 840-847.
53. Yajima, T. & Sakata, T. (1992) Core and periphery concentrations of short-chain fatty acids in luminal contents of the rat colon. Comp. Biochem. Physiol. Comp. Physiol. 103: 353-355.