Ionic liquids and proteases: A clean alliance for semisynthesis

ChemBioChem

Volumn 9, Issue 9, 2008, Pages 1493-1499

  Wehofsky, Nicole ^a   Wespe, Christian ^b   Cerovsky, Vaclav ^c   Pech, Andreas ^a   Hoess, Eva ^d   Rudolph, Rainer ^b   Bordusa, Frank ^b  

^a MAX PLANCK RESEARCH UNIT FOR ENZYMOLOGY OF PROTEIN FOLDING   (Germany)

^b MARTIN LUTHER UNIVERSITY HALLE WITTENBERG   (Germany)

^c INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY   (Czech Republic)

^d ROCHE DIAGNOSTICS GMBH   (Germany)

Author keywords

Chemoenzymatic synthesis; Ionic liquids; Peptides; Proteases; Substrate mimetics

Indexed keywords

1,3 DIMETHYL IMIDAZOLIUMDIMETHYLPHOSPHATE; IONIC LIQUID; PROTEINASE; UNCLASSIFIED DRUG; BUFFER; ORGANOPHOSPHATE; PEPTIDE FRAGMENT; PEPTIDE HYDROLASE; SOLVENT;

AQUEOUS SOLUTION; ARTICLE; BIOCATALYST; CATALYSIS; CHEMICAL REACTION; ENZYME ACTIVITY; MOLECULAR STABILITY; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN SYNTHESIS; SOLUBILITY; SOLVENT EFFECT; WILD TYPE; AMINO ACID SEQUENCE; ANIMAL; CATTLE; CHEMISTRY; DRUG EFFECT; ENZYME SPECIFICITY; HYDROLYSIS; METABOLISM; MOLECULAR GENETICS;

AMINO ACID SEQUENCE; ANIMALS; BUFFERS; CATALYSIS; CATTLE; HYDROLYSIS; IONIC LIQUIDS; MOLECULAR SEQUENCE DATA; PEPTIDE FRAGMENTS; PEPTIDE HYDROLASES; PHOSPHORIC ACID ESTERS; SOLUBILITY; SOLVENTS; SUBSTRATE SPECIFICITY;

EID: 49249137102     PISSN: 14394227     EISSN: 14397633     Source Type: Journal    
DOI: 10.1002/cbic.200800025     Document Type: Article

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