Efficient amelioration of carbon tetrachloride induced toxicity in isolated rat hepatocytes by Syzygium cumini Skeels extract

Toxicology in Vitro

Volumn 22, Issue 6, 2008, Pages 1440-1446

  Veigas, Jyothi M ^a   Shrivasthava, Richa ^a   Neelwarne, Bhagyalakshmi ^a  

^a CENTRAL FOOD TECHNOLOGICAL RESEARCH INSTITUTE   (India)

Author keywords

Anthocyanin; Antioxidant; Antioxidant enzymes; Black Java plum; Hepatoprotective

Indexed keywords

CARBON TETRACHLORIDE; CATALASE; GLUTATHIONE PEROXIDASE 1; LACTATE DEHYDROGENASE; PLANT EXTRACT; SUPEROXIDE DISMUTASE; SYZYGIUM CUMINI EXTRACT;

ANIMAL EXPERIMENT; ARTICLE; CELL DAMAGE; CELL PROTECTION; CELL VIABILITY; EXPERIMENTAL RAT; LIPID PEROXIDATION; LIVER CELL; MALE; NONHUMAN; RAT;

ANIMALS; ANTHOCYANINS; ANTIOXIDANTS; CARBON TETRACHLORIDE; CELL SURVIVAL; DOSE-RESPONSE RELATIONSHIP, DRUG; EUGENIA; FRUIT; GLUTATHIONE; GLUTATHIONE PEROXIDASE; HEPATOCYTES; L-LACTATE DEHYDROGENASE; LIPID PEROXIDATION; MALE; PLANT EXTRACTS; RATS; RATS, WISTAR;

PRUNUS DOMESTICA; PRUNUS NIGRA; RATTUS; SYZYGIUM CUMINI;

EID: 49149121745     PISSN: 08872333     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tiv.2008.04.015     Document Type: Article

References (38)

1. 4 toxicity. Journal of Natural Products 50 4 (1987) 612-617
2. Aebi H.E. Catalase in vitro. Methods Enzymology 105 (1984) 121-126
3. Andersen O.M., Viksund R.I., and Pedersen A.T. Malvidin 3-(6-acetylglucoside)-5-glucoside and other anthocyanins from flowers of Geranium sylvaticum. Phytochemistry 38 6 (1995) 1513-1517
4. Anonymous, 1976. Syzygium cumini. In: Chadha, Y.R. (Ed.), The Wealth of India, Raw materials - A Dictionary of Indian Raw Materials and Industrial Products, Publication and Information Directorate, Council for Scientific and Industrial Research, New Delhi, India, vol. X, p. 100.
5. Banerjee A., Dasgupta N., and De B. In vitro study of antioxidant activity of Syzygium cumini fruit. Food Chemistry 90 4 (2005) 727-733
6. Buege J.A., and Aust S.D. Microsomal lipid peroxidation. Methods Enzymology 52 (1978) 302-310
7. Cao G., Muccitelli H.U., Sanchez-Moreno C., and Prior R.L. Anthocyanins are absorbed in glycated forms in elderly women: a pharmacokinetic study. American Journal of Clinical Nutrition 73 5 (2001) 920-926
8. Eaton J.W. Actalasemia. In: Scriver C.R., Beaudet A.L., and Sly W.S. (Eds). The Metabolic Basis of Inherited Diseases (1989), McGraw-Hill, New York 1551-1561
9. Flohe A., and Gunzler W.A. Assays of glutathione peroxidase. Methods Enzymology 105 (1984) 114-120
10. Francis F.J. Analysis of anthocyanins. In: Markakis P. (Ed). Anthocyanins as Food Colors (1986), Academic press, New York 181-207
11. Galati G., Lin A., Sultan A., and O'Brien P.J. Cellular and in vivo hepatotoxicity caused by green tea phenolic acids and catechins. Free Radical Biology and Medicine 40 4 (2006) 570-580
12. Ghiselli A., Nardini M., Baldi A., and Scaccini C. Antioxidant activity of different phenolics fractions separated from Italian red wine. Journal of Agricultural and Food Chemistry 46 2 (1998) 361-367
13. Haidara K., Moffat P., and Denizeau F. Metallothionein induction attenuates the effects of glutathione depletors in rat hepatocytes. Toxicological Sciences 49 2 (1999) 297-305
14. Harter L.N. Critical values for Duncan's new multiple range test. Biometrics 16 4 (1960) 671-685
15. Intra J., and Kuo S. Physiological levels of tea catechins increase cellular lipid antioxidant activity of vitamin C and vitamin E in human intestinal Caco-2 cells. Chemico-Biological Interactions 169 2 (2007) 91-99
16. Johnston D.E., and Kroening C. Mechanism of early carbon tetrachloride toxicity in cultured rat hepatocytes. Pharmacology and Toxicology 83 6 (1998) 231-239
17. Kamendulis L.M., Jiang J., Xu Y., and Klaunig J.E. Induction of oxidative stress and oxidative damage in rat glial cells by the acrylonitrile. Carcinogenesis 20 8 (1999) 1555-1560
18. Keppler K., and Humpf H. Metabolism of anthocyanins and their phenolic degradation products by the intestinal microflora. Bioorganic and Medicinal Chemistry 13 17 (2005) 5195-5205
19. Kong J., Chia L., Goh N., Chia T., and Brouillard R. Analysis and biological activities of anthocyanins. Phytochemistry 64 5 (2003) 923-933
20. Lee A.U., and Farrell G.C. Mechanism of azathioprine-induced injury to rat hepatocytes: roles of glutathione depletion and mitochondrial injury. Journal of Hepatology 35 (2001) 756-764
21. Lin J.K., Chen P.C., Ho C.T., and Lin-Shiau S.Y. Inhibition of xanthine oxidase and suppression of intracellular reactive oxygen species in HL-60 cells by theaflavin-3, 3-digallate, (-)-epigallocatechin-3-gallate and propyl gallate. Journal of Agricultural and Food Chemistry 48 7 (2000) 2736-2743
22. 4-induced liver fibrosis in rats. Food and Chemical Toxicology 44 3 (2006) 336-343
23. Ljubuncic P., Portnaya I., Cogan U., Azaizeh H., and Bomzon A. Antioxidant activity of Crataegus aronia extract used in traditional Arab medicine in Israel. Journal of Ethnopharmacology 101 1-3 (2005) 153-161
24. Lowry O.H., Rosenberg N.J., Farr A.L., and Randall R.J. Protein measurement with the Folin-phenol reagent. Journal of Biological Chemistry 193 (1951) 265-267
25. Lu S.C. Regulation of hepatic glutathione synthesis: current concepts and controversies. FASEB Journal 13 10 (1999) 1169-1183
26. Martin-Aragon S., De Las Heras B., Sanchez-Reus M.I., and Benedi J. Pharmacological modification of endogenous antioxidant enzymes by ursolic acid on tetrachloride-induced liver damage in rats and primary cultures of rat hepatocytes. Experimental Toxicology and Pathology 53 (2001) 199-206
27. Masella R., Di Benedetto R., Vari R., Filesi C., and Giovannini C. Novel mechanisms of natural antioxidant compounds in biological systems: involvement of glutathione and glutathione-related enzymes. Journal of Nutritional Biochemistry 16 10 (2005) 577-586
28. Miccadei S., Kyle M.E., Gilfor D., and Farber J.L. Toxic consequence of the abrupt depletion of glutathione in cultured rat hepatocytes. Archives of Biochemistry and Biophysics 265 2 (1988) 311-320
29. Moldeus P., Hogberg J., and Orrenius S. Isolation and use of liver cells. Methods Enzymology 52 (1978) 60-71
30. Neuman M.G., Koren G., and Tiribelli C. In vitro assessment of the ethanol induced hepatotoxicity on HepG2 cell line. Biochemical and Biophysical Research Communications 197 2 (1993) 932-941
31. Popat A., Shear N.H., Malkiewicz I., Thomson S., and Neuman M.G. Mechanism of Impila (Callilepsis laureola)-induced cytotoxicity in HepG2 cells. Clinical Biochemistry 35 1 (2002) 57-64
32. Potapovich A.I., and Kostyuk V.A. Comparative study of antioxidant properties and cytoprotective activity of flavonoids. Biochemistry 68 5 (2003) 514-519
33. Ruch R.J., Klaunig J.E., Schultz N.E., Askari A.B., Lacher D.A., Pereira M.A., and Goldblatt P.J. Mechanisms of chloroform and carbon tetrachloride toxicity in primary cultured mouse hepatocytes. Environmental Health Perspectives 69 (1986) 301-305
34. Sarma A.D., and Sharma R. Anthocyanin-DNA copigmentation: mutual protection against oxidative damage. Phytochemistry 52 7 (1999) 1313-1318
35. Sharma S.B., Nasir A., Prabhu K.M., and Murthy P.S. Antihyperglycemic effect of the fruit-pulp of Eugenia jambolana in experimental diabetes mellitus. Journal of Ethnopharmacology 104 3 (2006) 367-373
36. Slater T.F. Free-radical mechanisms in tissue injury. Biochemical Journal 222 1 (1984) 1-15
37. Veigas J.M., Narayan M.S., Laxman P.M., and Neelwarne B. Chemical nature, stability and bioefficacies of anthocyanins from fruit peel of Syzygium cumini Skeels. Food Chemistry 105 2 (2007) 619-627
38. Ying-Jie W., Meng-Dong L., Yu-Min W., Jian D., and Qing-He N. Simplified isolation and spheroidal aggregate culture of rat hepatocytes. World Journal of Gastroenterology 4 1 (1998) 74-76