Cell surface targeting of VPAC1 receptors: Evidence for implication of a quality control system and the proteasome

Biochimica et Biophysica Acta - Molecular Cell Research

Volumn 1783, Issue 9, 2008, Pages 1663-1672

  Langer, Ingrid ^a   Leroy, Karelle ^a   Gaspard, Nathalie ^a   Brion, Jean Pierre ^a   Robberecht, Patrick ^a  

^a UNIVERSITÉ LIBRE DE BRUXELLES   (Belgium)

Author keywords

Cell surface expression; Glycosylation; GPCR; Proteasome; Trafficking; VIP receptor; VPAC1

Indexed keywords

G PROTEIN COUPLED RECEPTOR; PROTEASOME; VASOACTIVE INTESTINAL POLYPEPTIDE RECEPTOR 1; CHAPERONE; UBIQUITIN;

ANIMAL CELL; ARTICLE; CELL SURFACE; CHO CELL; CONTROLLED STUDY; ENDOPLASMIC RETICULUM; FLUORESCENCE MICROSCOPY; NONHUMAN; PRIORITY JOURNAL; PROTEIN FOLDING; PROTEIN GLYCOSYLATION; PROTEIN PROCESSING; PROTEIN TARGETING; ANIMAL; CELL MEMBRANE; CHEMISTRY; CRICETULUS; GENETICS; HAMSTER; METABOLISM; MUTATION; PROTEIN TRANSPORT; TEMPERATURE;

ANIMALS; CELL MEMBRANE; CHO CELLS; CRICETINAE; CRICETULUS; MOLECULAR CHAPERONES; MUTATION; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN TRANSPORT; RECEPTORS, VASOACTIVE INTESTINAL POLYPEPTIDE, TYPE I; TEMPERATURE; UBIQUITIN;

EID: 49149101395     PISSN: 01674889     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbamcr.2008.03.013     Document Type: Article

References (33)

1. Pierce K.L., Premont R.T., and Lefkowitz R.J. Seven-transmembrane receptors. Nat. Rev., Mol. Cell Biol. 3 (2002) 639-650
2. Duvernay M.T., Filipeanu C.M., and Wu G. The regulatory mechanisms of export trafficking of G protein-coupled receptors. Cell. Signal. 17 (2005) 1457-1465
3. Dong C., Filipeanu C.M., Duvernay M.T., and Wu G. Regulation of G protein-coupled receptor export trafficking. Biochim. Biophys. Acta 1768 (2007) 853-870
4. Wojcikiewicz R.J. Regulated ubiquitination of proteins in GPCR-initiated signaling pathways. Trends Pharmacol. Sci. 25 (2004) 35-41
5. Kopito R.R. Aggresomes, inclusion bodies and protein aggregation. Trends Cell Biol. 10 (2000) 524-530
6. Mironov A.A., Beznoussenko G.V., Polishchuk R.S., and Trucco A. Intra-Golgi transport: a way to a new paradigm?. Biochim. Biophys. Acta 1744 (2005) 340-350
7. Perry S.J., and Lefkowitz R.J. Arresting developments in heptahelical receptor signaling and regulation. Trends Cell Biol. 12 (2002) 130-138
8. Marchese A., Chen C., Kim Y.M., and Benovic J.L. The ins and outs of G protein-coupled receptor trafficking. Trends Biochem. Sci. 28 (2003) 369-376
9. Harmar A.J., Arimura A., Gozes I., Journot L., Laburthe M., Pisegna J.R., Rawlings S.R., Robberecht P., Said S.I., Sreedharan S.P., Wank S.A., and Waschek J.A. International Union of Pharmacology. XVIII. Nomenclature of receptors for vasoactive intestinal peptide and pituitary adenylate cyclase-activating polypeptide. Pharmacol. Rev. 50 (1998) 265-270
10. Couvineau A., Fabre C., Gaudin P., Maoret J.J., and Laburthe M. Mutagenesis of N-glycosylation sites in the human vasoactive intestinal peptide 1 receptor. Evidence that asparagine 58 or 69 is crucial for correct delivery of the receptor to plasma membrane. Biochemistry 35 (1996) 1745-1752
11. Langer I., Perret J., Vertongen P., Waelbroeck M., and Robberecht P. Vasoactive intestinal peptide (VIP) stimulates [Ca(2+)](i)and cyclic AMPin CHO cells expressing Galpha16. Cell Calcium 30 (2001) 229-234
12. Langer I., Vertongen P., Perret J., Waelbroeck M., and Robberecht P. A small sequence in the third intracellular loop of the VPAC(1) receptor is responsible for its efficient coupling to the calcium effector. Mol. Endocrinol. 16 (2002) 1089-1096
13. Schulz S., Rocken C., Mawrin C., Weise W., Hollt V., and Schulz S. Immunocytochemical identification of VPAC1, VPAC2, and PAC1 receptors in normal and neoplastic human tissues with subtype-specific antibodies. Clin. Cancer Res. 10 (2004) 8235-8242
14. Langlet C., Langer I., Vertongen P., Gaspard N., Vanderwinden J.M., and Robberecht P. Contribution of the carboxyl terminus of the VPAC1 receptor to agonist-induced receptor phosphorylation, internalization, and recycling. J. Biol. Chem. 280 (2005) 28034-28043
15. Salomon Y., Londos C., and Rodbell M. A highly sensitive adenylate cyclase assay. Anal. Biochem. 58 (1974) 541-548
16. Gourlet P., Vertongen P., Vandermeers A., Vandermeers-Piret M.C., Rathe J., De Neef P., Waelbroeck M., and Robberecht P. The long-acting vasoactive intestinal polypeptide agonist RO 25-1553 is highly selective of the VIP2 receptor subclass. Peptides 18 (1997) 403-408
17. Gourlet P., Vandermeers A., Vertongen P., Rathe J., De Neef P., Cnudde J., Waelbroeck M., and Robberecht P. Development of high affinity selective VIP1 receptor agonists. Peptides 18 (1997) 1539-1545
18. Romisch K. Endoplasmic reticulum-associated degradation. Annu. Rev. Cell Dev. Biol. 21 (2005) 435-456
19. Trombetta E.S., and Parodi A.J. Quality control and protein folding in the secretory pathway. Annu. Rev. Cell Dev. Biol. 19 (2003) 649-676
20. Ulloa-Aguirre A., Janovick J.A., Brothers S.P., and Conn P.M. Pharmacologic rescue of conformationally-defective proteins: implications for the treatment of human disease. Traffic 5 (2004) 821-837
21. Nachtergael I., Gaspard N., Langlet C., Robberecht P., and Langer I. Asn229 in the third helix of VPAC1 receptor is essential for receptor activation but not for receptor phosphorylation and internalization: comparison with Asn216 in VPAC2 receptor. Cell. Signal. 18 (2006) 2121-2130
22. Harikumar K.G., Morfis M.M., Lisenbee C.S., Sexton P.M., and Miller L.J. Constitutive formation of oligomeric complexes between family B G protein-coupled vasoactive intestinal polypeptide and secretin receptors. Mol. Pharmacol. 69 (2006) 363-373
23. Terrillon S., Durroux T., Mouillac B., Breit A., Ayoub M.A., Taulan M., Jockers R., Barberis C., and Bouvier M. Oxytocin and vasopressin V1a and V2 receptors form constitutive homo- and heterodimers during biosynthesis. Mol. Endocrinol. 17 (2003) 677-691
24. Salahpour A., Angers S., Mercier J.F., Lagace M., Marullo S., and Bouvier M. Homodimerization of the beta2-adrenergic receptor as a prerequisite for cell surface targeting. J. Biol. Chem. 279 (2004) 33390-33397
25. Pietila E.M., Tuusa J.T., Apaja P.M., Aatsinki J.T., Hakalahti A.E., Rajaniemi H.J., and Petaja-Repo U.E. Inefficient maturation of the rat luteinizing hormone receptor. A putative way to regulate receptor numbers at the cell surface. J. Biol. Chem. 280 (2005) 26622-26629
26. Petaja-Repo U.E., Hogue M., Laperriere A., Walker P., and Bouvier M. Export from the endoplasmic reticulum represents the limiting step in the maturation and cell surface expression of the human delta opioid receptor. J. Biol. Chem. 275 (2000) 13727-13736
27. Molinari M., and Helenius A. Chaperone selection during glycoprotein translocation into the endoplasmic reticulum. Science 288 (2000) 331-333
28. Herrick-Davis K., Weaver B.A., Grinde E., and Mazurkiewicz J.E. Serotonin 5-HT2C receptor homodimer biogenesis in the endoplasmic reticulum: real-time visualization with confocal fluorescence resonance energy transfer. J. Biol. Chem. 281 (2006) 27109-27116
29. Hague C., Uberti M.A., Chen Z., Hall R.A., and Minneman K.P. Cell surface expression of alpha1D-adrenergic receptors is controlled by heterodimerization with alpha1B-adrenergic receptors. J. Biol. Chem. 279 (2004) 15541-15549
30. Uberti M.A., Hague C., Oller H., Minneman K.P., and Hall R.A. Heterodimerization with beta2-adrenergic receptors promotes surface expression and functional activity of alpha1D-adrenergic receptors. J. Pharmacol. Exp. Ther. 313 (2005) 16-23
31. Zhou F., Filipeanu C.M., Duvernay M.T., and Wu G. Cell-surface targeting of alpha2-adrenergic receptors - inhibition by a transport deficient mutant through dimerization. Cell. Signal. 18 (2006) 318-327
32. Shenoy S.K., McDonald P.H., Kohout T.A., and Lefkowitz R.J. Regulation of receptor fate by ubiquitination of activated beta 2-adrenergic receptor and beta-arrestin. Science 294 (2001) 1307-1313
33. Shetzline M.A., Walker J.K., Valenzano K.J., and Premont R.T. Vasoactive intestinal polypeptide type-1 receptor regulation. desensitization, phosphorylation, and sequestration. J. Biol. Chem. 277 (2002) 25519-25526