The long-acting vasoactive intestinal polypeptide agonist RO 25-1553 is highly selective of the VIP2 receptor subclass

Peptides

Volumn 18, Issue 3, 1997, Pages 403-408

  Gourlet, Philippe ^a   Vertongen, Pascale ^a   Vandermeers, Andre ^a   Vandermeers Piret, Marie Claire ^a   Rathe, Jean ^a   De Neef, Philippe ^a   Waelbroeck, Magali ^a   Robberecht, Patrick ^a  

^a UNIVERSITÉ LIBRE DE BRUXELLES   (Belgium)

Author keywords

RO 25 1553; Selectivity; VIP2 receptor agonist

Indexed keywords

ADENYLATE CYCLASE; HYPOPHYSIS ADENYLATE CYCLASE ACTIVATING POLYPEPTIDE; HYPOPHYSIS ADENYLATE CYCLASE ACTIVATING POLYPEPTIDE 27; RECEPTOR SUBTYPE; RO 25 1553; UNCLASSIFIED DRUG; VASOACTIVE INTESTINAL POLYPEPTIDE AGONIST; VASOACTIVE INTESTINAL POLYPEPTIDE RECEPTOR;

ANAPHYLAXIS; ANIMAL CELL; ARTICLE; BRONCHOSPASM; BRONCHUS MUSCLE; CHO CELL; DIARRHEA; DRUG POTENCY; DRUG SELECTIVITY; EDEMA; EOSINOPHIL; HUMAN; HUMAN CELL; HYPOTENSION; INFLAMMATION; NONHUMAN; PNEUMONIA; PRIORITY JOURNAL; RECEPTOR OCCUPANCY; TRACHEA MUSCLE; TRACHEA OBSTRUCTION;

ADENYLATE CYCLASE; AMINO ACID SEQUENCE; ANIMALS; CHO CELLS; CRICETINAE; ENZYME ACTIVATION; HUMANS; MOLECULAR SEQUENCE DATA; NEUROPEPTIDES; PEPTIDES, CYCLIC; PITUITARY ADENYLATE CYCLASE-ACTIVATING POLYPEPTIDE; RATS; RECEPTORS, PITUITARY ADENYLATE CYCLASE-ACTIVATING POLYPEPTIDE; RECEPTORS, PITUITARY HORMONE; RECEPTORS, VASOACTIVE INTESTINAL PEPTIDE; RECEPTORS, VASOACTIVE INTESTINAL PEPTIDE, TYPE II; RECEPTORS, VASOACTIVE INTESTINAL POLYPEPTIDE, TYPE I; RECOMBINANT PROTEINS; TRANSFECTION; TUMOR CELLS, CULTURED; VASOACTIVE INTESTINAL PEPTIDE;

ANIMALIA; BRONCHUS; CRICETINAE; CRICETULUS GRISEUS; TRIXIS;

EID: 0030974306     PISSN: 01969781     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0196-9781(96)00322-1     Document Type: Article

References (30)

1. Abello J., Damien C., De Neef P., Tastenoy M., Hooghe R., Robberecht P., Christophe J. Properties of vasoactive-intestinal-peptide receptors and β -adrenoceptors in the murine radiation leukemia virus-induced lymphoma cell line BL/VL3. Eur. J. Biochem. 183:1989;263-267.
2. Bolin D. R., Cottrell J. M., O'Donnell M., Garippa R., O'Neill N. N-Terminal analogs of vasoactive intestinal peptide: Identification of a binding pharmacophore. Rivier J. E., Marshall G. R. Peptides: Chemistry and biology. Proceedings of the Eleventh American Peptide Symposium. 1989;208-210 ESCOM Science Publishers, Leiden, The Netherlands.
3. Bolin D. R., Cottrell J. M., Mickalewsky J., Garippa R., O'Neill N., Simko B., O'Donnell M. Degradation of vasoactive intestinal peptide in bronchial alveolar lavage fluid. Biomed. Res. 13:1992;25-30.
4. Buscail L., Gourlet P., Cauvin A., De Neef P., Gossen D., Arimura A., Miyata A., Coy D. H., Robberecht P., Christophe J. Presence of highly selective receptors for PACAP (pituitary adenylate cyclase activating peptide) in membranes from the rat pancreatic acinar cell line AR4-2J. FEBS Lett. 262:1990;77-81.
5. Christophe J. Type I receptors for PACAP (a neuropeptide even more important than VIP ?). Biochim. Biophys. Acta. 1154:1993;183-199.
6. Ciccarelli E., Vilardaga J. P., De Neef P., Di Paolo E., Waelbroeck M., Bollen A., Robberecht P. Properties of the VIP-PACAP type II receptor stably expressed in CHO cells. Regul. Pept. 54:1994;397-407.
7. Ciccarelli E., Svoboda M., De Neef P., Di Paolo E., Bollen A., Dubeaux C., Vilardaga J.-P., Waelbroeck M., Robberecht P. Pharmacological properties of two recombinant splice variants of the PACAP type I receptor transfected and stably expressed in CHO cells. Eur. J. Pharmacol. 288:1995;259-267.
8. Couvineau A., Rouyer-Fessard C., Darmoul D., Maoret J.-J., Carrero I., Ogier-Denis E., Laburthe M. Human intestinal VIP receptor: Cloning and functional expression of two cDNA encoding proteins with different N-terminal domains. Biochem. Biophys. Res. Commun. 200:1994;769-776.
9. Couvineau A., Rouyer-Fessard C., Darmoul D., Maoret J-J., Carrero I., Ogier-Denis E., Laburthe M. Cloning of a common VIP-PACAP receptor from human intestine. Rosselin G. Vasoactive intestinal peptide; pituitary adenylate cyclase activating polypeptide and related regulatory peptides. 1994;129-142 World Scientific, New York.
10. 2 receptors in human THP-1 monocytes/macrophages: A possible role in the regulation of superoxide anions production. Regul. Pept. 26:1989;158.
11. Gourlet P., Vandermeers A., Vandermeers-Piret M.-C., Rathé J., P. De Neef P., Robberecht P. Fragments of pituitary adenylate cyclase activating polypeptide discriminate between type I and II recombinant receptors. Eur. J. Pharmacol. 287:1995;7-11.
12. Inagaki N., Yoshida H., Mizuta M., Mizuno N., Fujii Y., Gonoi T., Miyazaki J.-I., Seino S. Cloning and functional characterization of a third pituitary adenylate cyclase-activating polypeptide receptor subtype expressed in insulin-secreting cells. Proc. Natl. Acad. Sci. USA. 91:1994;2679-2683.
13. Ishihara T., Shigemoto R., Mori K., Takahashi K., Nagata S. Functional expression and tissue distribution of a novel receptor for vasoactive intestinal polypeptide. Neuron. 8:1992;811-819.
14. Krejs G. J. Effect of vasoactive intestinal peptide in man. Ann. NY Acad. Sci. 527:1988;501-507.
15. Krempels K., Usdin T. B., Harta G., Mezey E. PACAP acts through VIP type 2 receptors in the rat testis. Neuropeptides. 29:1995;315-320.
16. Luis J., Said S. I. Characterization of VIP- and Helodermin-preferring receptors on human small cell lung carcinoma cell lines. Peptides. 11:1990;1239-1244.
17. 2 receptor: Molecular characterisation of a cDNA encoding a novel receptor for vasoactive intestinal peptide. FEBS Lett. 334:1993;3-8.
18. O'Donnell M., Garippa R. J., O'Neill N. C., Bolin D. R., Cottrell J. M. Structure-activity studies of vasoactive intestinal polypeptide. J. Biol. Chem. 266:1991;6389-6392.
19. O'Donnell M., Garippa R. J., Rinaldi N., Selig W. M., Simko B., Renzetti L., Tannu S. A., Wasserman M. A., Welton A., Bolin D. R. Ro 25-1553: A novel, long-acting vasoactive intestinal peptide agonist. Part I: In vitro and in vivo bronchodilator studies. J. Pharmacol. Exp. Ther. 270:1994;1282-1288.
20. O'Donnell M., Garippa R. J., Rinaldi N., Selig W. M., Tocker J. E., Tannu S. A., Wasserman M. A., Welton A., Bolin D. R. RO 25-1553: A novel, long-acting vasoactive intestinal peptide agonist. Part II: Effect on in vitro and in vivo models of pulmonary anaphylaxis. J. Pharmacol. Exp. Ther. 270:1994;1289-1294.
21. Rawlings S. R. PACAP; PACAP receptors and intracellular signalling. Mol. Cell. Endocrinol. 101:1994;C5-C9.
22. Robberecht P., Waelbroeck M., De Neef P., Tastenoy M., Gourlet P., Cogniaux J., Christophe J. A new type of functional VIP receptor has an affinity for helodermin in human SUP-T1 lymphoblasts. FEBS Lett. 228:1988;351-355.
23. Robberecht P., De Neef P., Gourlet P., Cauvin A., Coy D. H., Christophe J. Pharmacological characterization of the novel helodermin/VIP receptor present in human SUP-T1 lymphoma cell membranes. Regul. Pept. 26:1988;117-126.
24. Robberecht P., Gourlet P., Vertongen P., Svoboda M. Characterization of the VIP receptor from the SUP T1 lymphoblasts. Adv. Neuroimmunol. 6:1996;49-57.
25. Rorstad O. P., Wanke I., Coy D. H., Fournier A., Huang M. Selectivity for binding of peptide analogs to vascular receptors for vasoactive intestinal peptide. Mol. Pharmacol. 37:1990;971-977.
26. Salomon Y., Londos C., Rodbell M. A highly sensitive adenylate cyclase assay. Anal. Biochem. 58:1974;541-548.
27. Svoboda M., Tastenoy M., Van Rampelbergh J., Goossens J.-F., De Neef P., Waelbroeck M., Robberecht P. Molecular cloning and functional characterization of a human VIP receptor from SUP-T1 lymphoblasts. Biochem. Biophys. Res. Commun. 205:1994;1617-1624.
28. Usdin T. B., Bonner T. I., Mezey E. Two receptors for vasoactive intestinal polypeptide with similar specificity and complementary distributions. Endocrinology. 135:1994;2662-2680.
29. Vandermeers A., Gourlet P., Vandermeers-Piret M.-C., Cauvin, De Neef P., Rathé J., Svoboda M., Robberecht P., Christophe J. Chemical, immunological and biological properties of peptides like vasoactive-intestinal-peptide and peptide-histidine-isoleucinamide extracted from the venom of two lizards (Heloderma horridum and Heloderma suspectum). Eur. J. Biochem. 164:1987;321-327.
30. Vilardaga J. P., Ciccarelli E., Dubeaux C., De Neef P., Bollen A., Robberecht P. Properties and regulation of the coupling to adenylate cyclase of the secretin receptor stably transfected in CHO cells. Mol. Pharmacol. 45:1994;1022-1028.