-
1
-
-
0036200749
-
Striking differences in glucose and lactate levels between brain extracellular fluid and plasma in conscious human subjects: effects of hyperglycemia and hypoglycemia
-
Abi-Saab W.M., Maggs D.G., Jones T., Jacob R., Srihari V., Thomson J., Kerr D., Leone P., Krystal J.H., Spencer D.D., During M.J., and Sherwin R.S. Striking differences in glucose and lactate levels between brain extracellular fluid and plasma in conscious human subjects: effects of hyperglycemia and hypoglycemia. J. Cereb. Blood Flow Metab. 22 (2002) 271-279
-
(2002)
J. Cereb. Blood Flow Metab.
, vol.22
, pp. 271-279
-
-
Abi-Saab, W.M.1
Maggs, D.G.2
Jones, T.3
Jacob, R.4
Srihari, V.5
Thomson, J.6
Kerr, D.7
Leone, P.8
Krystal, J.H.9
Spencer, D.D.10
During, M.J.11
Sherwin, R.S.12
-
2
-
-
28044442099
-
Brain lactate kinetics: modeling evidence for neuronal lactate uptake upon activation
-
Aubert A., Costalat R., Magistretti P.J., and Pellerin L. Brain lactate kinetics: modeling evidence for neuronal lactate uptake upon activation. Proc. Natl. Acad. Sci. U S A 102 (2005) 16448-16453
-
(2005)
Proc. Natl. Acad. Sci. U S A
, vol.102
, pp. 16448-16453
-
-
Aubert, A.1
Costalat, R.2
Magistretti, P.J.3
Pellerin, L.4
-
3
-
-
34247185200
-
A coherent neurobiological framework for functional neuroimaging provided by a model integrating compartmentalized energy metabolism
-
Aubert A., Pellerin L., Magistretti P.J., and Costalat R. A coherent neurobiological framework for functional neuroimaging provided by a model integrating compartmentalized energy metabolism. Proc. Natl. Acad. Sci. USA 104 (2007) 4188-4193
-
(2007)
Proc. Natl. Acad. Sci. USA
, vol.104
, pp. 4188-4193
-
-
Aubert, A.1
Pellerin, L.2
Magistretti, P.J.3
Costalat, R.4
-
4
-
-
0035114149
-
A novel postsynaptic density protein: the monocarboxylate transporter MCT2 is co-localized with delta-glutamate receptors in postsynaptic densities of parallel fiber-Purkinje cell synapses
-
Bergersen L., Waerhaug O., Helm J., Thomas M., Laake P., Davies A.J., Wilson M.C., Halestrap A.P., and Ottersen O.P. A novel postsynaptic density protein: the monocarboxylate transporter MCT2 is co-localized with delta-glutamate receptors in postsynaptic densities of parallel fiber-Purkinje cell synapses. Exp. Brain Res. 136 (2001) 523-534
-
(2001)
Exp. Brain Res.
, vol.136
, pp. 523-534
-
-
Bergersen, L.1
Waerhaug, O.2
Helm, J.3
Thomas, M.4
Laake, P.5
Davies, A.J.6
Wilson, M.C.7
Halestrap, A.P.8
Ottersen, O.P.9
-
5
-
-
0036130456
-
Immunogold cytochemistry identifies specialized membrane domains for monocarboxylate transport in the central nervous system
-
Bergersen L., Rafiki A., and Ottersen O.P. Immunogold cytochemistry identifies specialized membrane domains for monocarboxylate transport in the central nervous system. Neurochem. Res. 27 (2002) 89-96
-
(2002)
Neurochem. Res.
, vol.27
, pp. 89-96
-
-
Bergersen, L.1
Rafiki, A.2
Ottersen, O.P.3
-
6
-
-
15244358180
-
Selective postsynaptic co-localization of MCT2 with AMPA receptor GluR2/3 subunits at excitatory synapses exhibiting AMPA receptor trafficking
-
Bergersen L.H., Magistretti P.J., and Pellerin L. Selective postsynaptic co-localization of MCT2 with AMPA receptor GluR2/3 subunits at excitatory synapses exhibiting AMPA receptor trafficking. Cereb. Cortex 15 (2005) 361-370
-
(2005)
Cereb. Cortex
, vol.15
, pp. 361-370
-
-
Bergersen, L.H.1
Magistretti, P.J.2
Pellerin, L.3
-
7
-
-
0030774069
-
Comparison of lactate transport in astroglial cells and monocarboxylate transporter 1 (MCT 1) expressing Xenopus laevis oocytes. Expression of two different monocarboxylate transporters in astroglial cells and neurons
-
Bröer S., Rahman B., Pellegri G., Pellerin L., Martin J.L., Verleysdonk S., Hamprecht B., and Magistretti P.J. Comparison of lactate transport in astroglial cells and monocarboxylate transporter 1 (MCT 1) expressing Xenopus laevis oocytes. Expression of two different monocarboxylate transporters in astroglial cells and neurons. J. Biol. Chem. 272 (1997) 30096-30102
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 30096-30102
-
-
Bröer, S.1
Rahman, B.2
Pellegri, G.3
Pellerin, L.4
Martin, J.L.5
Verleysdonk, S.6
Hamprecht, B.7
Magistretti, P.J.8
-
8
-
-
0039351371
-
Characterization of the high-affinity monocarboxylate transporter MCT2 in Xenopus laevis oocytes
-
Bröer S., Bröer A., Schneider H.P., Stegen C., Halestrap A.P., and Deitmer J.W. Characterization of the high-affinity monocarboxylate transporter MCT2 in Xenopus laevis oocytes. Biochem. J. 31 (1999) 529-535
-
(1999)
Biochem. J.
, vol.31
, pp. 529-535
-
-
Bröer, S.1
Bröer, A.2
Schneider, H.P.3
Stegen, C.4
Halestrap, A.P.5
Deitmer, J.W.6
-
9
-
-
34347242128
-
Noradrenaline enhances the expression of the neuronal monocarboxylate transporter MCT2 by translational activation via stimulation of PI3K/Akt and the mTOR/S6K pathway
-
Chenal J., and Pellerin L. Noradrenaline enhances the expression of the neuronal monocarboxylate transporter MCT2 by translational activation via stimulation of PI3K/Akt and the mTOR/S6K pathway. J. Neurochem. 102 (2007) 389-397
-
(2007)
J. Neurochem.
, vol.102
, pp. 389-397
-
-
Chenal, J.1
Pellerin, L.2
-
10
-
-
37749021939
-
Insulin and IGF-1 enhance the expression of the neuronal monocarboxylate transporter MCT2 by translational activation via stimulation of the phosphoinositide 3-kinase-Akt-mammalian target of rapamycin pathway
-
Chenal J., Pierre K., and Pellerin L. Insulin and IGF-1 enhance the expression of the neuronal monocarboxylate transporter MCT2 by translational activation via stimulation of the phosphoinositide 3-kinase-Akt-mammalian target of rapamycin pathway. Eur. J. Neurosci. 27 (2008) 53-65
-
(2008)
Eur. J. Neurosci.
, vol.27
, pp. 53-65
-
-
Chenal, J.1
Pierre, K.2
Pellerin, L.3
-
11
-
-
32644483710
-
Expression of the monocarboxylate transporter MCT1 in the adult human brain cortex
-
Chiry O., Pellerin L., Monnet-Tschudi F., Fishbein W.N., Merezhinskaya N., Magistretti P.J., and Clarke S. Expression of the monocarboxylate transporter MCT1 in the adult human brain cortex. Brain Res. 1070 (2006) 65-70
-
(2006)
Brain Res.
, vol.1070
, pp. 65-70
-
-
Chiry, O.1
Pellerin, L.2
Monnet-Tschudi, F.3
Fishbein, W.N.4
Merezhinskaya, N.5
Magistretti, P.J.6
Clarke, S.7
-
12
-
-
0842322960
-
A reduced cerebral metabolic ratio in exercise reflects metabolism and not accumulation of lactate within the human brain
-
Dalsgaard M.K., Quistorff B., Danielsen E.R., Selmer C., Vogelsang T., and Secher N.H. A reduced cerebral metabolic ratio in exercise reflects metabolism and not accumulation of lactate within the human brain. J. Physiol. 15 (2004) 571-578
-
(2004)
J. Physiol.
, vol.15
, pp. 571-578
-
-
Dalsgaard, M.K.1
Quistorff, B.2
Danielsen, E.R.3
Selmer, C.4
Vogelsang, T.5
Secher, N.H.6
-
13
-
-
33745726895
-
Fuelling cerebral activity in exercising man
-
Dalsgaard M.K. Fuelling cerebral activity in exercising man. J. Cereb. Blood Flow Metab. 26 (2006) 731-750
-
(2006)
J. Cereb. Blood Flow Metab.
, vol.26
, pp. 731-750
-
-
Dalsgaard, M.K.1
-
14
-
-
0037963512
-
Cell-specific expression pattern of monocarboxylate transporters in astrocytes and neurons observed in different mouse brain cortical cell cultures
-
Debernardi R., Pierre K., Lengacher S., Magistretti P.J., and Pellerin L. Cell-specific expression pattern of monocarboxylate transporters in astrocytes and neurons observed in different mouse brain cortical cell cultures. J. Neurosci. Res. 73 (2003) 141-155
-
(2003)
J. Neurosci. Res.
, vol.73
, pp. 141-155
-
-
Debernardi, R.1
Pierre, K.2
Lengacher, S.3
Magistretti, P.J.4
Pellerin, L.5
-
15
-
-
0742324436
-
Immunocytochemical expression of monocarboxylate transporters in the human visual cortex at midgestation
-
Fayol L., Baud O., Monier A., Pellerin L., Magistretti P.J., Evrard P., and Verney C. Immunocytochemical expression of monocarboxylate transporters in the human visual cortex at midgestation. Dev. Brain Res. 148 (2004) 69-76
-
(2004)
Dev. Brain Res.
, vol.148
, pp. 69-76
-
-
Fayol, L.1
Baud, O.2
Monier, A.3
Pellerin, L.4
Magistretti, P.J.5
Evrard, P.6
Verney, C.7
-
16
-
-
0036301412
-
Relative distribution of three major lactate transporters in frozen human tissues and their localization in unfixed skeletal muscle
-
Fishbein W.N., Merezhinskaya N., and Foellmer J.W. Relative distribution of three major lactate transporters in frozen human tissues and their localization in unfixed skeletal muscle. Muscle Nerve 26 (2002) 101-112
-
(2002)
Muscle Nerve
, vol.26
, pp. 101-112
-
-
Fishbein, W.N.1
Merezhinskaya, N.2
Foellmer, J.W.3
-
17
-
-
0035953105
-
Expression of monocarboxylate transporter MCT1 in normal and neoplastic human CNS tissues
-
Froberg M.K., Gerhart D.Z., Enerson B.E., Manivel C., Guzman -Paz M., Seacotte N., and Drewes L.R. Expression of monocarboxylate transporter MCT1 in normal and neoplastic human CNS tissues. Neuroreport 12 (2001) 761-765
-
(2001)
Neuroreport
, vol.12
, pp. 761-765
-
-
Froberg, M.K.1
Gerhart, D.Z.2
Enerson, B.E.3
Manivel, C.4
Guzman -Paz, M.5
Seacotte, N.6
Drewes, L.R.7
-
18
-
-
0030837750
-
Expression of monocarboxylate transporter MCT1 by brain endothelium and glia in adult and suckling rats
-
Gerhart D.Z., Enerson B.E., Zhdankina O.Y., Leino R.L., and Drewes L.R. Expression of monocarboxylate transporter MCT1 by brain endothelium and glia in adult and suckling rats. Am. J. Physiol. 273 (1997) E207-E213
-
(1997)
Am. J. Physiol.
, vol.273
-
-
Gerhart, D.Z.1
Enerson, B.E.2
Zhdankina, O.Y.3
Leino, R.L.4
Drewes, L.R.5
-
19
-
-
1242340302
-
The SLC16 gene family-from monocarboxylate transporters (MCTs) to aromatic amino acid transporters and beyond
-
Halestrap A.P., and Meredith D. The SLC16 gene family-from monocarboxylate transporters (MCTs) to aromatic amino acid transporters and beyond. Pflugers Arch. 447 (2004) 619-628
-
(2004)
Pflugers Arch.
, vol.447
, pp. 619-628
-
-
Halestrap, A.P.1
Meredith, D.2
-
20
-
-
0034041755
-
Monocarboxylic acid transporters, MCT1 and MCT2, in cortical astrocytes in vitro and in vivo
-
Hanu R., McKenna M., O'Neill A., Resneck W.G., and Bloch R.J. Monocarboxylic acid transporters, MCT1 and MCT2, in cortical astrocytes in vitro and in vivo. Am. J. Physiol. 278 (2000) C921-C930
-
(2000)
Am. J. Physiol.
, vol.278
-
-
Hanu, R.1
McKenna, M.2
O'Neill, A.3
Resneck, W.G.4
Bloch, R.J.5
-
21
-
-
0030909127
-
Cloning of the monocarboxylate transporter isoform MCT2 from rat testis provides evidence that expression in tissues is species-specific and may involve post-transcriptional regulation
-
Jackson V.N., Price N.T., Carpenter L., and Halestrap A.P. Cloning of the monocarboxylate transporter isoform MCT2 from rat testis provides evidence that expression in tissues is species-specific and may involve post-transcriptional regulation. Biochem. J. 324 (1997) 447-453
-
(1997)
Biochem. J.
, vol.324
, pp. 447-453
-
-
Jackson, V.N.1
Price, N.T.2
Carpenter, L.3
Halestrap, A.P.4
-
22
-
-
0031719871
-
Monocarboxylate transporter expression in mouse brain
-
Koehler-Stec E.M., Simpson I.A., Vannucci S.J., Landschulz K.T., and Landschulz W.H. Monocarboxylate transporter expression in mouse brain. Am. J. Physiol. 275 (1998) E516-E524
-
(1998)
Am. J. Physiol.
, vol.275
-
-
Koehler-Stec, E.M.1
Simpson, I.A.2
Vannucci, S.J.3
Landschulz, K.T.4
Landschulz, W.H.5
-
23
-
-
0032582702
-
Human monocarboxylate transporter 2 (MCT2) is a high affinity pyruvate transporter
-
Lin R.Y., Vera J.C., Chaganti R.S., and Golde D.W. Human monocarboxylate transporter 2 (MCT2) is a high affinity pyruvate transporter. J. Biol. Chem. 273 (1998) 28959-28965
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 28959-28965
-
-
Lin, R.Y.1
Vera, J.C.2
Chaganti, R.S.3
Golde, D.W.4
-
24
-
-
0037466252
-
The aerobic brain: lactate decrease at the onset of neural activity
-
Mangia S., Garreffa G., Bianciardi M., Giove F., Di Salle F., and Maraviglia B. The aerobic brain: lactate decrease at the onset of neural activity. Neuroscience 118 (2003) 7-10
-
(2003)
Neuroscience
, vol.118
, pp. 7-10
-
-
Mangia, S.1
Garreffa, G.2
Bianciardi, M.3
Giove, F.4
Di Salle, F.5
Maraviglia, B.6
-
25
-
-
0032584084
-
Expression of monocarboxylate transporter mRNAs in mouse brain: support for a distinct role of lactate as an energy substrate for the neonatal vs. adult brain
-
Pellerin L., Pellegri G., Martin J.L., and Magistretti P.J. Expression of monocarboxylate transporter mRNAs in mouse brain: support for a distinct role of lactate as an energy substrate for the neonatal vs. adult brain. Proc. Natl. Acad. Sci. U. S. A. 95 (1998) 3990-3995
-
(1998)
Proc. Natl. Acad. Sci. U. S. A.
, vol.95
, pp. 3990-3995
-
-
Pellerin, L.1
Pellegri, G.2
Martin, J.L.3
Magistretti, P.J.4
-
26
-
-
12244262261
-
Cellular and subcellular distribution of monocarboxylate transporters in cultured brain cells and in the adult brain
-
Pellerin L., Bergersen L.H., Halestrap A.P., and Pierre K. Cellular and subcellular distribution of monocarboxylate transporters in cultured brain cells and in the adult brain. J. Neurosci. Res. 79 (2005) 55-64
-
(2005)
J. Neurosci. Res.
, vol.79
, pp. 55-64
-
-
Pellerin, L.1
Bergersen, L.H.2
Halestrap, A.P.3
Pierre, K.4
-
27
-
-
34547823399
-
Activity-dependent regulation of energy metabolism by astrocytes: an update
-
Pellerin L., Bouzier-Sore A.K., Aubert A., Serres S., Merle M., Costalat R., and Magistretti P.J. Activity-dependent regulation of energy metabolism by astrocytes: an update. Glia 55 (2007) 1251-1262
-
(2007)
Glia
, vol.55
, pp. 1251-1262
-
-
Pellerin, L.1
Bouzier-Sore, A.K.2
Aubert, A.3
Serres, S.4
Merle, M.5
Costalat, R.6
Magistretti, P.J.7
-
28
-
-
0034721575
-
Cell-specific localization of monocarboxylate transporters, MCT1 and MCT2, in the adult mouse brain revealed by double immunohistochemical labeling and confocal microscopy
-
Pierre K., Pellerin L., Debernardi R., Riederer B.M., and Magistretti P.J. Cell-specific localization of monocarboxylate transporters, MCT1 and MCT2, in the adult mouse brain revealed by double immunohistochemical labeling and confocal microscopy. Neuroscience 100 (2000) 617-627
-
(2000)
Neuroscience
, vol.100
, pp. 617-627
-
-
Pierre, K.1
Pellerin, L.2
Debernardi, R.3
Riederer, B.M.4
Magistretti, P.J.5
-
29
-
-
0036254152
-
MCT2 is a major neuronal monocarboxylate transporter in the adult mouse brain
-
Pierre K., Magistretti P.J., and Pellerin L. MCT2 is a major neuronal monocarboxylate transporter in the adult mouse brain. J. Cereb. Blood Flow Metab. 22 (2002) 586-595
-
(2002)
J. Cereb. Blood Flow Metab.
, vol.22
, pp. 586-595
-
-
Pierre, K.1
Magistretti, P.J.2
Pellerin, L.3
-
30
-
-
0141655180
-
Noradrenaline enhances monocarboxylate transporter 2 expression in cultured mouse cortical neurons via a translational regulation
-
Pierre K., Debernardi R., Magistretti P.J., and Pellerin L. Noradrenaline enhances monocarboxylate transporter 2 expression in cultured mouse cortical neurons via a translational regulation. J. Neurochem. 86 (2003) 1468-1476
-
(2003)
J. Neurochem.
, vol.86
, pp. 1468-1476
-
-
Pierre, K.1
Debernardi, R.2
Magistretti, P.J.3
Pellerin, L.4
-
31
-
-
21344444566
-
Monocarboxylate transporters in the central nervous system: distribution, regulation and function
-
Pierre K., and Pellerin L. Monocarboxylate transporters in the central nervous system: distribution, regulation and function. J. Neurochem. 94 (2005) 1-14
-
(2005)
J. Neurochem.
, vol.94
, pp. 1-14
-
-
Pierre, K.1
Pellerin, L.2
-
32
-
-
0032518981
-
Cloning and sequencing of four new mammalian monocarboxylate transporter (MCT) homologues confirms the existence of a transporter family with an ancient past
-
Price N.T., Jackson V.N., and Halestrap A.P. Cloning and sequencing of four new mammalian monocarboxylate transporter (MCT) homologues confirms the existence of a transporter family with an ancient past. Biochem. J. 329 (1998) 321-328
-
(1998)
Biochem. J.
, vol.329
, pp. 321-328
-
-
Price, N.T.1
Jackson, V.N.2
Halestrap, A.P.3
-
33
-
-
0026009448
-
Lactate rise detected by 1H NMR in human visual cortex during physiologic stimulation
-
Prichard J., Rothman D., Novotny E., Petroff O., Kuwabara T., Avison M., Howseman A., Hanstock C., and Shulman R. Lactate rise detected by 1H NMR in human visual cortex during physiologic stimulation. Proc. Natl. Acad. Sci. U. S. A. 88 (1991) 5829-5831
-
(1991)
Proc. Natl. Acad. Sci. U. S. A.
, vol.88
, pp. 5829-5831
-
-
Prichard, J.1
Rothman, D.2
Novotny, E.3
Petroff, O.4
Kuwabara, T.5
Avison, M.6
Howseman, A.7
Hanstock, C.8
Shulman, R.9
-
34
-
-
0242485280
-
Highly differential expression of the monocarboxylate transporters MCT2 and MCT4 in the developing rat brain
-
Rafiki A., Bouland J.L., Halestrap A.P., Ottersen O.P., and Bergersen L. Highly differential expression of the monocarboxylate transporters MCT2 and MCT4 in the developing rat brain. Neuroscience 122 (2003) 677-688
-
(2003)
Neuroscience
, vol.122
, pp. 677-688
-
-
Rafiki, A.1
Bouland, J.L.2
Halestrap, A.P.3
Ottersen, O.P.4
Bergersen, L.5
-
35
-
-
0031279854
-
Cytochrome oxidase, acetylcholinesterase, and NADPH-diaphorase staining in human supratemporal and insular cortex: evidence for multiple auditory areas
-
Rivier F., and Clarke S. Cytochrome oxidase, acetylcholinesterase, and NADPH-diaphorase staining in human supratemporal and insular cortex: evidence for multiple auditory areas. Neuroimage 6 (1997) 288-304
-
(1997)
Neuroimage
, vol.6
, pp. 288-304
-
-
Rivier, F.1
Clarke, S.2
-
36
-
-
0037782010
-
Lactate: a preferred fuel for human brain metabolism in vivo
-
Smith D., Pernet A., Hallett W.A., Bingham E., Marsden P.K., and Amiel S.A. Lactate: a preferred fuel for human brain metabolism in vivo. J. Cereb. Blood Flow Metab. 23 (2003) 658-664
-
(2003)
J. Cereb. Blood Flow Metab.
, vol.23
, pp. 658-664
-
-
Smith, D.1
Pernet, A.2
Hallett, W.A.3
Bingham, E.4
Marsden, P.K.5
Amiel, S.A.6
-
37
-
-
27244442141
-
Transfer of glycogen-derived lactate from astrocytes to axons via specific monocarboxylate transporters supports mouse optic nerve activity
-
Tekkök S.B., Brown A.M., Westenbroek R., Pellerin L., and Ransom B.R. Transfer of glycogen-derived lactate from astrocytes to axons via specific monocarboxylate transporters supports mouse optic nerve activity. J. Neurosci. Res. 81 (2005) 644-652
-
(2005)
J. Neurosci. Res.
, vol.81
, pp. 644-652
-
-
Tekkök, S.B.1
Brown, A.M.2
Westenbroek, R.3
Pellerin, L.4
Ransom, B.R.5
-
38
-
-
37449028557
-
Alternative promoter usage and alternative splicing contribute to mRNA heterogeneity of mouse monocarboxylate transporter 2
-
Zhang S.X.L., Searcy T.R., Wu Y., Gozal D., and Wang Y. Alternative promoter usage and alternative splicing contribute to mRNA heterogeneity of mouse monocarboxylate transporter 2. Physiol. Genomics 32 (2007) 95-104
-
(2007)
Physiol. Genomics
, vol.32
, pp. 95-104
-
-
Zhang, S.X.L.1
Searcy, T.R.2
Wu, Y.3
Gozal, D.4
Wang, Y.5
|