-
1
-
-
0036200749
-
Striking differences in glucose and lactate levels between brain extracellular fluid and plasma in conscious human subjects: Effects of hyperglycemia and hypoglycemia
-
Abi-Saab WM, Maggs DG, Jones T, Jacob R, Srihari V, Thompson J, Kerr D, Leone P, Krystal JH, Spencer DD, During MJ, Sherwin RS. 2002. Striking differences in glucose and lactate levels between brain extracellular fluid and plasma in conscious human subjects: effects of hyperglycemia and hypoglycemia. J Cereb Blood Flow Metab 22:271-279.
-
(2002)
J Cereb Blood Flow Metab
, vol.22
, pp. 271-279
-
-
Abi-Saab, W.M.1
Maggs, D.G.2
Jones, T.3
Jacob, R.4
Srihari, V.5
Thompson, J.6
Kerr, D.7
Leone, P.8
Krystal, J.H.9
Spencer, D.D.10
During, M.J.11
Sherwin, R.S.12
-
2
-
-
0001050235
-
The neuroglia elements of the brain
-
Andriezen WL. 1893. The neuroglia elements of the brain. Br Med J 2: 227-230.
-
(1893)
Br Med J
, vol.2
, pp. 227-230
-
-
Andriezen, W.L.1
-
4
-
-
25744477746
-
On the role of D-lactate as a competitive inhibitor for astrocyte to axon transfer of L-lactate in a central white matter pathway
-
Baltan Tekkök S, Brown AM, Ransom BR. 2003. On the role of D-lactate as a competitive inhibitor for astrocyte to axon transfer of L-lactate in a central white matter pathway. J Physiol 551P:C66.
-
(2003)
J Physiol
, vol.551 P
-
-
Baltan Tekkök, S.1
Brown, A.M.2
Ransom, B.R.3
-
5
-
-
0029990892
-
Selective distribution of lactate dehydrogenase isoenzymes in neurons and astrocytes of human brain
-
Bittar PG, Charnay Y, Pellerin L, Bouras C, Magistretti PJ. 1996. Selective distribution of lactate dehydrogenase isoenzymes in neurons and astrocytes of human brain. J Cereb Blood Flow Metab 16:1079-1089.
-
(1996)
J Cereb Blood Flow Metab
, vol.16
, pp. 1079-1089
-
-
Bittar, P.G.1
Charnay, Y.2
Pellerin, L.3
Bouras, C.4
Magistretti, P.J.5
-
6
-
-
0345700729
-
Local lactate perfusion of the ventromedial hypothalamus suppresses hypoglycemic counterregulation
-
Borg MA, Tamborlane WV, Shulman GI, Sherwin RS. 2003. Local lactate perfusion of the ventromedial hypothalamus suppresses hypoglycemic counterregulation. Diabetes 52:663-666.
-
(2003)
Diabetes
, vol.52
, pp. 663-666
-
-
Borg, M.A.1
Tamborlane, W.V.2
Shulman, G.I.3
Sherwin, R.S.4
-
8
-
-
0242406757
-
Lactate is a preferential oxidative energy substrate over glucose for neurons in culture
-
Bouzier-Sore AK, Voisin P, Canioni P, Magistretti PJ, Pellerin L. 2003. Lactate is a preferential oxidative energy substrate over glucose for neurons in culture. J Cereb Blood Flow Metab 23:1298-1306.
-
(2003)
J Cereb Blood Flow Metab
, vol.23
, pp. 1298-1306
-
-
Bouzier-Sore, A.K.1
Voisin, P.2
Canioni, P.3
Magistretti, P.J.4
Pellerin, L.5
-
9
-
-
0030774069
-
Comparison of lactate transport in astroglial cells and monocarboxylate transporter 1 (MCT 1) expressing Xenopus laevis oocytes. Expression of two different monocarboxylate transporters in astroglial cells and neurons
-
Bröer S, Rahman B, Pellegri G, Pellerin L, Martin JL, Verleysdonk S, Hamprecht B, Magistretti PJ. 1997. Comparison of lactate transport in astroglial cells and monocarboxylate transporter 1 (MCT 1) expressing Xenopus laevis oocytes. Expression of two different monocarboxylate transporters in astroglial cells and neurons. J Biol Chem 272:30096-30102.
-
(1997)
J Biol Chem
, vol.272
, pp. 30096-30102
-
-
Bröer, S.1
Rahman, B.2
Pellegri, G.3
Pellerin, L.4
Martin, J.L.5
Verleysdonk, S.6
Hamprecht, B.7
Magistretti, P.J.8
-
10
-
-
0032127127
-
Characterization of the monocarboxylate transporter 1 expressed in Xenopus laevis oocytes by changes in cytosolic pH
-
Bröer S, Schneider HP, Bröer A, Rahman B, Hamprecht B, Deitmer JW. 1998. Characterization of the monocarboxylate transporter 1 expressed in Xenopus laevis oocytes by changes in cytosolic pH. Biochem J 333:167-174.
-
(1998)
Biochem J
, vol.333
, pp. 167-174
-
-
Bröer, S.1
Schneider, H.P.2
Bröer, A.3
Rahman, B.4
Hamprecht, B.5
Deitmer, J.W.6
-
11
-
-
0039351371
-
Characterization of the high-affinity monocarboxylate transporter MCT2 in Xenopus laevis oocytes
-
Bröer S, Bröer A, Schneider HP, Stegen C, Halestrap AP, Deitmer JW. 1999. Characterization of the high-affinity monocarboxylate transporter MCT2 in Xenopus laevis oocytes. Biochem J 341:529-535.
-
(1999)
Biochem J
, vol.341
, pp. 529-535
-
-
Bröer, S.1
Bröer, A.2
Schneider, H.P.3
Stegen, C.4
Halestrap, A.P.5
Deitmer, J.W.6
-
12
-
-
0035577691
-
Metabolic substrates other than glucose support axon function in central white matter
-
Brown AM, Wender R, Ransom BR. 2001. Metabolic substrates other than glucose support axon function in central white matter. J Neurosci Res 66:839-843.
-
(2001)
J Neurosci Res
, vol.66
, pp. 839-843
-
-
Brown, A.M.1
Wender, R.2
Ransom, B.R.3
-
13
-
-
0037497019
-
Glycogen regulation and functional role in mouse white matter
-
549.2
-
Brown AM, Baltan Tekkök S, Ransom BR. 2003. Glycogen regulation and functional role in mouse white matter. J Physiol 549.2:501-512.
-
(2003)
J Physiol
, pp. 501-512
-
-
Brown, A.M.1
Baltan Tekkök, S.2
Ransom, B.R.3
-
14
-
-
2942534211
-
Energy transfer from astrocytes to axons: The role of CNS glycogen
-
Brown AM, Baltan Tekkök S, Ransom B. 2004a. Energy transfer from astrocytes to axons: the role of CNS glycogen. Neurochem Int 45:529-536.
-
(2004)
Neurochem Int
, vol.45
, pp. 529-536
-
-
Brown, A.M.1
Baltan Tekkök, S.2
Ransom, B.3
-
15
-
-
33751582492
-
Metabolic coupling between glia and neurons
-
Hatton GI, Parpura V, editors. Norwall, MA: Kluwer.
-
Brown AM, Baltan Tekkök S, Ransom BR. 2004b. Metabolic coupling between glia and neurons. In: Hatton GI, Parpura V, editors. Glial neuronal signaling. Norwall, MA: Kluwer. p 279-296.
-
(2004)
Glial Neuronal Signaling
, pp. 279-296
-
-
Brown, A.M.1
Baltan Tekkök, S.2
Ransom, B.R.3
-
16
-
-
0035906537
-
Further studies on the effects of topical lactate on amino acid efflux from the ischemic rat cortex
-
Cassady CJ, Phillis JW, O'Regan MH. 2001. Further studies on the effects of topical lactate on amino acid efflux from the ischemic rat cortex. Brain Res 901:30-37.
-
(2001)
Brain Res
, vol.901
, pp. 30-37
-
-
Cassady, C.J.1
Phillis, J.W.2
O'Regan, M.H.3
-
17
-
-
0035281837
-
Neuroprotective role of monocarbpxylate transport during glucose deprivation in slice cultures of rat hippocampus
-
Cater HL, Benham CD, Sundstrom LE. 2001. Neuroprotective role of monocarbpxylate transport during glucose deprivation in slice cultures of rat hippocampus. J Physiol 531:459-466.
-
(2001)
J Physiol
, vol.531
, pp. 459-466
-
-
Cater, H.L.1
Benham, C.D.2
Sundstrom, L.E.3
-
18
-
-
0242574396
-
Energy substrates for neurons during neural activity: A critical review of the astrocyte-neuron lactate shuttle hypothesis
-
Chih CP, Roberts EL. 2003. Energy substrates for neurons during neural activity: a critical review of the astrocyte-neuron lactate shuttle hypothesis. J Cereb Blood Flow Metab 23:1263-1281.
-
(2003)
J Cereb Blood Flow Metab
, vol.23
, pp. 1263-1281
-
-
Chih, C.P.1
Roberts, E.L.2
-
19
-
-
0035478762
-
Do active cerebral neurons really use lactate rather than glucose?
-
Chih C, Lipton P, Roberts EL. 2001. Do active cerebral neurons really use lactate rather than glucose? Trends Neurosci 24;573-578.
-
(2001)
Trends Neurosci
, vol.24
, pp. 573-578
-
-
Chih, C.1
Lipton, P.2
Roberts, E.L.3
-
20
-
-
0037963512
-
Cell-specific expression pattern of monocarboxylate transporters in astrocytes and neurons observed in different mouse brain cortical cell cultures
-
Debernardi R, Pierre K, Lengacher S, Magistretti PJ, Pellerin L. 2003. Cell-specific expression pattern of monocarboxylate transporters in astrocytes and neurons observed in different mouse brain cortical cell cultures. J Neurosci Res 73:141-155.
-
(2003)
J Neurosci Res
, vol.73
, pp. 141-155
-
-
Debernardi, R.1
Pierre, K.2
Lengacher, S.3
Magistretti, P.J.4
Pellerin, L.5
-
21
-
-
0027216810
-
Glycogen in astrocytes: Possible function as lactate supply for neighboring cells
-
Dringen R, Gebhardt R, Hamprecht B. 1993. Glycogen in astrocytes: possible function as lactate supply for neighboring cells. Brain Res 623: 208-214.
-
(1993)
Brain Res
, vol.623
, pp. 208-214
-
-
Dringen, R.1
Gebhardt, R.2
Hamprecht, B.3
-
22
-
-
0036374171
-
Identification of putative mammalian D-lactate dehydrogenase enzymes
-
Flick MJ, Konieczny SF. 2002. Identification of putative mammalian D-lactate dehydrogenase enzymes. Biochem Biophys Res Commun 295: 910-916.
-
(2002)
Biochem Biophys Res Commun
, vol.295
, pp. 910-916
-
-
Flick, M.J.1
Konieczny, S.F.2
-
23
-
-
0031440995
-
Endogenous monocarboxylates sustain hippocampal synaptic function and morphological integrity during energy deprivation
-
Izumi Y, Benz AM, Katsuki H, Zorumski CF. 1997. Endogenous monocarboxylates sustain hippocampal synaptic function and morphological integrity during energy deprivation. J Neurosci 17:9448-9457.
-
(1997)
J Neurosci
, vol.17
, pp. 9448-9457
-
-
Izumi, Y.1
Benz, A.M.2
Katsuki, H.3
Zorumski, C.F.4
-
24
-
-
0030044996
-
The kinetics, substrate, and inhibitor specificity of the monocarboxylate (lactate) transporter of rat liver cells determined using the fluorescent intracellular pH indicator, 2′,7′-bis(-carboxyethyl)-5(6)- carboxyfluorescein
-
Jackson VN, Halestrap AP. 1996. The kinetics, substrate, and inhibitor specificity of the monocarboxylate (lactate) transporter of rat liver cells determined using the fluorescent intracellular pH indicator, 2′,7′-bis(-carboxyethyl)-5(6)-carboxyfluorescein. J Biol Chem 271:861-868.
-
(1996)
J Biol Chem
, vol.271
, pp. 861-868
-
-
Jackson, V.N.1
Halestrap, A.P.2
-
25
-
-
0031719871
-
Monocarboxylate transporter expression in mouse brain
-
Koehler-Stec EM, Simpson IA, Vannucci SJ, Landschulz KT, Landschulz WH. 1998. Monocarboxylate transporter expression in mouse brain. Am J Physiol 275:E516-E524.
-
(1998)
Am J Physiol
, vol.275
-
-
Koehler-Stec, E.M.1
Simpson, I.A.2
Vannucci, S.J.3
Landschulz, K.T.4
Landschulz, W.H.5
-
26
-
-
0020582922
-
Lactate uptake and release in the presence of glucose by sympathetic ganglia of chicken embryos and by neuronal and non-neuronal cultures prepared from these ganglia
-
Larrabee MG. 1983. Lactate uptake and release in the presence of glucose by sympathetic ganglia of chicken embryos and by neuronal and non-neuronal cultures prepared from these ganglia. J Neurochem 40:1237-1250.
-
(1983)
J Neurochem
, vol.40
, pp. 1237-1250
-
-
Larrabee, M.G.1
-
27
-
-
0029661937
-
2 production between glucose and lactate in excised sympathetic ganglia, with implications for brain
-
2 production between glucose and lactate in excised sympathetic ganglia, with implications for brain. J Neurochem 67:1726-1734.
-
(1996)
J Neurochem
, vol.67
, pp. 1726-1734
-
-
Larrabee, M.G.1
-
28
-
-
0000017491
-
Brain energy metabolism: An integrated cellular perspective
-
Bloom FE, Kupfer DJ, editors. New York: Raven Press
-
Magistretti PJ, Pellerin L, Martin JL. 1995. Brain energy metabolism: an integrated cellular perspective. In: Bloom FE, Kupfer DJ, editors. Psychopharmacology: the fourth generation of progress. New York: Raven Press, p 657-670.
-
(1995)
Psychopharmacology: The Fourth Generation of Progress
, pp. 657-670
-
-
Magistretti, P.J.1
Pellerin, L.2
Martin, J.L.3
-
29
-
-
0001316349
-
Substances which support respiration and metabolic response to electrical impulses in human cerebral tissues
-
McIlwain H. 1953. Substances which support respiration and metabolic response to electrical impulses in human cerebral tissues. J Neurol Neurosurg Psychiatry 16:257-266.
-
(1953)
J Neurol Neurosurg Psychiatry
, vol.16
, pp. 257-266
-
-
McIlwain, H.1
-
31
-
-
0035576881
-
α-cyano-4-hydroxycinnamate decreases both glucose and lactate metabolism in neurons and astrocytes: Implications for lactate as an energy substrate for neurons
-
McKenna MC, Hopkins IB, Carey A. 2001. α-Cyano-4-hydroxycinnamate decreases both glucose and lactate metabolism in neurons and astrocytes: implications for lactate as an energy substrate for neurons. J Neurosci Res 66:747-754.
-
(2001)
J Neurosci Res
, vol.66
, pp. 747-754
-
-
McKenna, M.C.1
Hopkins, I.B.2
Carey, A.3
-
32
-
-
0027244386
-
Carrier-mediated transport of lactic acid in cultured neurons and astrocytes
-
Nedergaard M, Goldman SA. 1993. Carrier-mediated transport of lactic acid in cultured neurons and astrocytes. Am J Physiol 265:R282-289.
-
(1993)
Am J Physiol
, vol.265
-
-
Nedergaard, M.1
Goldman, S.A.2
-
33
-
-
0141533205
-
New roles for astrocytes: Redefining the functional architecture of the brain
-
Nedergaard M, Ransom B, Goldman SA. 2003. New roles for astrocytes: redefining the functional architecture of the brain. Trends Neurosci 26: 523-530.
-
(2003)
Trends Neurosci
, vol.26
, pp. 523-530
-
-
Nedergaard, M.1
Ransom, B.2
Goldman, S.A.3
-
34
-
-
0028080101
-
Glutamate uptake into astrocytes stimulates aerobic glycolysis: A mechanism coupling neuronal activity to glucose utilization
-
Pellerin L, Magistretti PJ. 1994. Glutamate uptake into astrocytes stimulates aerobic glycolysis: a mechanism coupling neuronal activity to glucose utilization. Proc Natl Acad Sci U S A 91:10625-10629.
-
(1994)
Proc Natl Acad Sci U S A
, vol.91
, pp. 10625-10629
-
-
Pellerin, L.1
Magistretti, P.J.2
-
36
-
-
1642457265
-
Neuroenergetics: Calling upon astrocytes to satisfy hungry neurons
-
Pellerin L, Magistretti PJ. 2004. Neuroenergetics: calling upon astrocytes to satisfy hungry neurons. Neuroscientist 10:53-62.
-
(2004)
Neuroscientist
, vol.10
, pp. 53-62
-
-
Pellerin, L.1
Magistretti, P.J.2
-
37
-
-
0032584084
-
Expression of monocarboxylate transporter mRNAs in mouse brain: Support for a distinct role of lactate as an energy substrate for the neonatal vs. adult brain
-
Pellerin L, Pellegri G, Martin JL, Magistretti PJ. 1998a. Expression of monocarboxylate transporter mRNAs in mouse brain: support for a distinct role of lactate as an energy substrate for the neonatal vs. adult brain. Proc Natl Acad Sci U S A 95:3990-3995.
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 3990-3995
-
-
Pellerin, L.1
Pellegri, G.2
Martin, J.L.3
Magistretti, P.J.4
-
38
-
-
0031731776
-
Evidence supporting the existence of an activity-dependent astrocyte-neuron lactate shuttle
-
Pellerin L, Pellegri G, Bittar PG, Charnay Y, Bouras C, Martin JL, Stella N, Magistretti PJ. 1998b. Evidence supporting the existence of an activity-dependent astrocyte-neuron lactate shuttle. Dev Neurosci 20: 291-299.
-
(1998)
Dev Neurosci
, vol.20
, pp. 291-299
-
-
Pellerin, L.1
Pellegri, G.2
Bittar, P.G.3
Charnay, Y.4
Bouras, C.5
Martin, J.L.6
Stella, N.7
Magistretti, P.J.8
-
39
-
-
12244262261
-
Cellular and subcellular distribution of monocarboxylate transporters in cultured brain cells and in the adult brain
-
Pellerin L, Halestrap AP, Pierre K. 2005. Cellular and subcellular distribution of monocarboxylate transporters in cultured brain cells and in the adult brain. J Neurosci Res 79:55-64.
-
(2005)
J Neurosci Res
, vol.79
, pp. 55-64
-
-
Pellerin, L.1
Halestrap, A.P.2
Pierre, K.3
-
40
-
-
0034721575
-
Cell-specific localization of monocarboxylate transporters, MCT1 and MCT2, in the adult mouse brain revealed by double immunohistochemical labeling and confocal microscopy
-
Pierre K, Pellerin L, Debernardi R, Riederer BM, Magistretti PJ. 2000. Cell-specific localization of monocarboxylate transporters, MCT1 and MCT2, in the adult mouse brain revealed by double immunohistochemical labeling and confocal microscopy. Neuroscience 100:617-627.
-
(2000)
Neuroscience
, vol.100
, pp. 617-627
-
-
Pierre, K.1
Pellerin, L.2
Debernardi, R.3
Riederer, B.M.4
Magistretti, P.J.5
-
41
-
-
0036254152
-
MCT2 is a major neuronal monocarboxylate transporter in the adult mouse brain
-
Pierre K, Magistretti PJ, Pellerin L. 2002. MCT2 is a major neuronal monocarboxylate transporter in the adult mouse brain. J Cereb Blood Flow Metab 22:586-595.
-
(2002)
J Cereb Blood Flow Metab
, vol.22
, pp. 586-595
-
-
Pierre, K.1
Magistretti, P.J.2
Pellerin, L.3
-
42
-
-
27444433942
-
Optic nerve injury
-
Drance SM Drance SM, editors. Amsterdam: Kugler Publications
-
Ransom BR. 1995. Optic nerve injury. In: Drance SM Drance SM, editors. Optic nerve in injury. Amsterdam: Kugler Publications, p 181-198.
-
(1995)
Optic Nerve in Injury
, pp. 181-198
-
-
Ransom, B.R.1
-
43
-
-
0035577774
-
Lactate reduces glutamate-induced neurotoxicity in rat cortex
-
Ros J, Pecinska N, Alessandri B, Landolt H, Fillenz M. 2001. Lactate reduces glutamate-induced neurotoxicity in rat cortex. J Neurosci Res 66:790-794.
-
(2001)
J Neurosci Res
, vol.66
, pp. 790-794
-
-
Ros, J.1
Pecinska, N.2
Alessandri, B.3
Landolt, H.4
Fillenz, M.5
-
44
-
-
0030982027
-
Brain lactate is an obligatory aerobic energy substrate for functional recovery after hypoxia: Further in vitro validation
-
Schurr A, Payne RS, Miller JJ, Rigor BM. 1997. Brain lactate is an obligatory aerobic energy substrate for functional recovery after hypoxia: further in vitro validation. J Neurochem 69:423-426.
-
(1997)
J Neurochem
, vol.69
, pp. 423-426
-
-
Schurr, A.1
Payne, R.S.2
Miller, J.J.3
Rigor, B.M.4
-
45
-
-
0032929864
-
An increase in lactate output by brain tissue serves to meet the energy needs of glutamate-activated neurons
-
Schurr A, Miller JJ, Payne RS, Rigor BM. 1999. An increase in lactate output by brain tissue serves to meet the energy needs of glutamate-activated neurons. J Neurosci 19:34-39.
-
(1999)
J Neurosci
, vol.19
, pp. 34-39
-
-
Schurr, A.1
Miller, J.J.2
Payne, R.S.3
Rigor, B.M.4
-
47
-
-
0025728907
-
Compound action potential of nerve recorded by suction electrode: A theoretical and experimental analysis
-
Stys PK, Ransom BR, Waxman SG. 1991. Compound action potential of nerve recorded by suction electrode: a theoretical and experimental analysis. Brain Res 546:18-32.
-
(1991)
Brain Res
, vol.546
, pp. 18-32
-
-
Stys, P.K.1
Ransom, B.R.2
Waxman, S.G.3
-
48
-
-
0028210971
-
Glial cells transform glucose to alanine, which fuels the neurons in the honeybee retina
-
Tsacopoulos M, Veuthey AL, Saravelos SG, Perrottet P, Tsoupras G. 1994. Glial cells transform glucose to alanine, which fuels the neurons in the honeybee retina. J Neurosci 14:1339-1351.
-
(1994)
J Neurosci
, vol.14
, pp. 1339-1351
-
-
Tsacopoulos, M.1
Veuthey, A.L.2
Saravelos, S.G.3
Perrottet, P.4
Tsoupras, G.5
-
49
-
-
0029927343
-
Metabolic coupling between glia and neurons
-
Tsacopoulos M, Magistretti PJ. 1996. Metabolic coupling between glia and neurons. J Neurosci 16:877-885.
-
(1996)
J Neurosci
, vol.16
, pp. 877-885
-
-
Tsacopoulos, M.1
Magistretti, P.J.2
-
50
-
-
0034666454
-
Astrocytic glycogen influences axon function and survival during glucose deprivation in central white matter
-
Wender R, Brown AM, Fern R, Swanson RA, Farrell K, Ransom BR. 2000. Astrocytic glycogen influences axon function and survival during glucose deprivation in central white matter. J Neurosci 20:6804-6810.
-
(2000)
J Neurosci
, vol.20
, pp. 6804-6810
-
-
Wender, R.1
Brown, A.M.2
Fern, R.3
Swanson, R.A.4
Farrell, K.5
Ransom, B.R.6
|