Design, synthesis, and structure-affinity relationship studies in NK1 receptor ligands based on azole-fused quinolinecarboxamide moieties

Bioorganic and Medicinal Chemistry

Volumn 16, Issue 14, 2008, Pages 6850-6859

  Cappelli, Andrea ^a   Giuliani, Germano ^a   Anzini, Maurizio ^a   Riitano, Daniela ^b   Giorgi, Gianluca ^a   Vomero, Salvatore ^a  

^a UNIVERSITY OF SIENA   (Italy)

^b ISTITUTO SUPERIORE DI SANITÀ   (Italy)

Author keywords

Amide derivatives; Neurokinin; NK1 receptor; Substance P; Synthesis

Indexed keywords

3 QUINOLINECARBOXAMIDE DERIVATIVE; AMIDE; NEUROKININ 1 RECEPTOR; PYRROLE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BINDING SITE; CONTROLLED STUDY; DRUG BINDING; DRUG DESIGN; DRUG STRUCTURE; DRUG SYNTHESIS; NONHUMAN; STRUCTURE ACTIVITY RELATION;

AMIDES; AZOLES; BINDING SITES; DRUG DESIGN; HUMANS; LIGANDS; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP; QUINOLINES; RECEPTORS, NEUROKININ-1;

EID: 48949115546     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2008.05.067     Document Type: Article

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