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Volumn 9, Issue 10, 2001, Pages 2727-2743
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Synthesis and biological evaluations of quinoline-based HMG-CoA reductase inhibitors
a
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Author keywords
[No Author keywords available]
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Indexed keywords
3,5 DIHYDROXYHEPTENOIC ACID DERIVATIVE;
ACETIC ACID ETHYL ESTER;
ALDEHYDE DERIVATIVE;
ALKYL GROUP;
BENZENE DERIVATIVE;
CARBOXYLIC ACID DERIVATIVE;
COMPACTIN;
CYCLOPROPANE DERIVATIVE;
DESMETHYLMEVALONIC ACID;
ENZYME INHIBITOR;
ETHYL 2 CYCLOPROPYL 4 (4 FLUOROPHENYL) 3 QUINOLINE CARBOXYLIC ACID;
HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE;
HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR;
MEVALONIC ACID;
MEVINOLIN;
PITAVASTATIN;
PRAVASTATIN;
QUINOLINE;
QUINOLINECARBALDEHYDE;
QUINOLINECARBOXYLIC ACID ESTER DERIVATIVE;
UNCLASSIFIED DRUG;
CHEMICAL REACTION;
CONFERENCE PAPER;
DNA FLANKING REGION;
DRUG INHIBITION;
DRUG STRUCTURE;
DRUG SYNTHESIS;
ENZYME INHIBITION;
EVALUATION;
IN VITRO STUDY;
MEDICAL LITERATURE;
POLYMERIZATION;
REACTION ANALYSIS;
SEQUENCE HOMOLOGY;
ANIMALS;
ANTILIPEMIC AGENTS;
CATALYSIS;
CHOLESTEROL;
CHROMATOGRAPHY, HIGH PRESSURE LIQUID;
COMBINATORIAL CHEMISTRY TECHNIQUES;
CYCLIZATION;
HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS;
LIVER;
MAGNETIC RESONANCE SPECTROSCOPY;
MALE;
MASS SPECTROMETRY;
MICROSOMES, LIVER;
MOLECULAR STRUCTURE;
QUINOLINES;
RATS;
RATS, WISTAR;
SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION;
SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION;
STEREOISOMERISM;
STRUCTURE-ACTIVITY RELATIONSHIP;
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EID: 0034840928
PISSN: 09680896
EISSN: None
Source Type: Journal
DOI: 10.1016/S0968-0896(01)00198-5 Document Type: Article |
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Times cited : (95)
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References (51)
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