메뉴 건너뛰기




Volumn 289, Issue , 2008, Pages 208-216

What can we Learn from the Disrupted in Schizophrenia 1 Interactome: Lessons for Target Identification and Disease Biology?

Author keywords

Glutamatergic neurotransmission; Measurable cognitive deficits; Physiological enzymatic role; Psychotic and cognitive symptoms; Schizophrenia and bipolar disorders

Indexed keywords

DISC1 PROTEIN, HUMAN; MICROTUBULE ASSOCIATED PROTEIN; NDE1 PROTEIN, HUMAN; NERVE PROTEIN; NEUROLEPTIC AGENT;

EID: 48849099092     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1002/9780470751251.ch17     Document Type: Chapter
Times cited : (21)

References (27)
  • 1
    • 33748686575 scopus 로고    scopus 로고
    • Cyclic nucleotide phosphodiesterases: molecular regulation to clinical use
    • Bender AT, Beavo JA 2006 Cyclic nucleotide phosphodiesterases: molecular regulation to clinical use. Pharmacol Rev 58:488-520.
    • (2006) Pharmacol Rev , vol.58 , pp. 488-520
    • Bender, A.T.1    Beavo, J.A.2
  • 2
    • 3242806757 scopus 로고    scopus 로고
    • Clinical phenotypes associated with DISC1, a candidate gene for schizophrenia
    • Blackwood DH, Muir WJ 2004 Clinical phenotypes associated with DISC1, a candidate gene for schizophrenia. Neurotox Res 6:35-41.
    • (2004) Neurotox Res , vol.6 , pp. 35-41
    • Blackwood, D.H.1    Muir, W.J.2
  • 3
    • 10744229990 scopus 로고    scopus 로고
    • Disrupted in Schizophrenia 1 and Nudel form a neurodevelopmentally regulated protein complex: implications for schizophrenia and other major neurological disorders
    • Brandon NJ, Handford EJ, Schurov I et al 2004 Disrupted in Schizophrenia 1 and Nudel form a neurodevelopmentally regulated protein complex: implications for schizophrenia and other major neurological disorders. Mol Cell Neurosci 25:42-55.
    • (2004) Mol Cell Neurosci , vol.25 , pp. 42-55
    • Brandon, N.J.1    Handford, E.J.2    Schurov, I.3
  • 4
    • 24044449980 scopus 로고    scopus 로고
    • DISC1 and neurocognitive function in schizophrenia
    • Burdick KE, Hodgkinson CA, Szeszko PR et al 2005 DISC1 and neurocognitive function in schizophrenia. Neuroreport 16:1399-1402.
    • (2005) Neuroreport , vol.16 , pp. 1399-1402
    • Burdick, K.E.1    Hodgkinson, C.A.2    Szeszko, P.R.3
  • 5
    • 20844463251 scopus 로고    scopus 로고
    • Variation in DISC1 affects hippocampal structure and function and increases risk for schizophrenia
    • Callicott JH, Straub RE, Pezawas L et al 2005 Variation in DISC1 affects hippocampal structure and function and increases risk for schizophrenia. Proc Natl Acad Sci USA 102:8627-8632.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 8627-8632
    • Callicott, J.H.1    Straub, R.E.2    Pezawas, L.3
  • 6
    • 33845748185 scopus 로고    scopus 로고
    • Disrupted in Schizophrenia 1 interactome: evidence for the close connectivity of risk genes and a potential synaptic basis for schizophrenia
    • Camargo LM, Collura V, Rain JC et al 2007 Disrupted in Schizophrenia 1 interactome: evidence for the close connectivity of risk genes and a potential synaptic basis for schizophrenia. Mol Psychiatry 12:74-86.
    • (2007) Mol Psychiatry , vol.12 , pp. 74-86
    • Camargo, L.M.1    Collura, V.2    Rain, J.C.3
  • 7
    • 27744554247 scopus 로고    scopus 로고
    • Association of DISC1/TRAX haplotypes with schizophrenia, reduced prefrontal gray matter, and impaired short- and long-term memory
    • Cannon TD, Hennah W, van Erp TG et al 2005 Association of DISC1/TRAX haplotypes with schizophrenia, reduced prefrontal gray matter, and impaired short- and long-term memory. Arch Gen Psychiatry 62:1205-1213.
    • (2005) Arch Gen Psychiatry , vol.62 , pp. 1205-1213
    • Cannon, T.D.1    Hennah, W.2    van Erp, T.G.3
  • 8
    • 33644617753 scopus 로고    scopus 로고
    • Analysis of the human protein interactome and comparison with yeast, worm and fly interaction datasets
    • Gandhi TK, Zhong J, Mathivanan S et al 2006 Analysis of the human protein interactome and comparison with yeast, worm and fly interaction datasets. Nat Genet 38:285-293.
    • (2006) Nat Genet , vol.38 , pp. 285-293
    • Gandhi, T.K.1    Zhong, J.2    Mathivanan, S.3
  • 9
    • 12344327212 scopus 로고    scopus 로고
    • Schizophrenia genes, gene expression, and neuropathology:on the matter of their convergence
    • Harrison PJ, Weinberger DR 2005 Schizophrenia genes, gene expression, and neuropathology:on the matter of their convergence. Mol Psychiatry 10:40-68.
    • (2005) Mol Psychiatry , vol.10 , pp. 40-68
    • Harrison, P.J.1    Weinberger, D.R.2
  • 10
    • 20144374692 scopus 로고    scopus 로고
    • Inhibition of NUDEL (nuclear distribution element-like)-oligopeptidase activity by disrupted-in-schizophrenia 1
    • Hayashi MA, Portaro FC, Bastos MF et al 2005 Inhibition of NUDEL (nuclear distribution element-like)-oligopeptidase activity by disrupted-in-schizophrenia 1. Proc Natl Acad Sci USA 102:3828-3833.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 3828-3833
    • Hayashi, M.A.1    Portaro, F.C.2    Bastos, M.F.3
  • 11
    • 33745221854 scopus 로고    scopus 로고
    • A review of Disrupted-In-Schizophrenia-1 (DISC1): neurodevelopment, cognition, and mental conditions
    • Ishizuka K, Paek M, Kamiya A, Sawa A 2006 A review of Disrupted-In-Schizophrenia-1 (DISC1): neurodevelopment, cognition, and mental conditions. Biol Psychiatry 59:1189-1197.
    • (2006) Biol Psychiatry , vol.59 , pp. 1189-1197
    • Ishizuka, K.1    Paek, M.2    Kamiya, A.3    Sawa, A.4
  • 12
    • 3042822399 scopus 로고    scopus 로고
    • Plakins: goliaths that link cell junctions and the cytoskeleton
    • Jefferson JJ, Leung CL, Liem RK 2004 Plakins: goliaths that link cell junctions and the cytoskeleton. Nat Rev Mol Cell Biol 5:542-553.
    • (2004) Nat Rev Mol Cell Biol , vol.5 , pp. 542-553
    • Jefferson, J.J.1    Leung, C.L.2    Liem, R.K.3
  • 13
    • 28544453286 scopus 로고    scopus 로고
    • A schizophrenia-associated mutation of DISC1 perturbs cerebral cortex development
    • Kamiya A, Kubo K, Tomoda T et al 2005 A schizophrenia-associated mutation of DISC1 perturbs cerebral cortex development. Nat Cell Biol 7:1167-1178.
    • (2005) Nat Cell Biol , vol.7 , pp. 1167-1178
    • Kamiya, A.1    Kubo, K.2    Tomoda, T.3
  • 14
    • 33750388150 scopus 로고    scopus 로고
    • DISC1-NDEL1/NUDEL protein interaction, an essential component for neurite outgrowth, is modulated by genetic variations of DISC1
    • Kamiya A, Tomoda T, Chang J et al 2006 DISC1-NDEL1/NUDEL protein interaction, an essential component for neurite outgrowth, is modulated by genetic variations of DISC1. Hum Mol Genet 15:3313-3323.
    • (2006) Hum Mol Genet , vol.15 , pp. 3313-3323
    • Kamiya, A.1    Tomoda, T.2    Chang, J.3
  • 15
    • 33744985583 scopus 로고    scopus 로고
    • DISC1 immunoreactivity at the light and ultrastructural level in the human neocortex
    • Kirkpatrick B, Xu L, Cascella N, Ozeki Y, Sawa A, Roberts RC 2006 DISC1 immunoreactivity at the light and ultrastructural level in the human neocortex. J Comp Neurol 497:436-450.
    • (2006) J Comp Neurol , vol.497 , pp. 436-450
    • Kirkpatrick, B.1    Xu, L.2    Cascella, N.3    Ozeki, Y.4    Sawa, A.5    Roberts, R.C.6
  • 16
    • 0034702026 scopus 로고    scopus 로고
    • Disruption of two novel genes by a translocation co-segregating with schizophrenia
    • Millar JK, Wilson-Annan JC, Anderson S et al 2000 Disruption of two novel genes by a translocation co-segregating with schizophrenia. Hum Mol Genet 9:1415-1423.
    • (2000) Hum Mol Genet , vol.9 , pp. 1415-1423
    • Millar, J.K.1    Wilson-Annan, J.C.2    Anderson, S.3
  • 17
    • 27944502874 scopus 로고    scopus 로고
    • DISC1 and PDE4B are interacting genetic factors in schizophrenia that regulate cAMP signaling
    • Millar JK, Pickard BS, Mackie S et al 2005a DISC1 and PDE4B are interacting genetic factors in schizophrenia that regulate cAMP signaling. Science 310:1187-1191.
    • (2005) Science , vol.310 , pp. 1187-1191
    • Millar, J.K.1    Pickard, B.S.2    Mackie, S.3
  • 18
    • 28344457312 scopus 로고    scopus 로고
    • Disrupted in schizophrenia 1 (DISC1):subcellular targeting and induction of ring mitochondria
    • Millar JK, James R, Christie S, Porteous DJ 2005b Disrupted in schizophrenia 1 (DISC1):subcellular targeting and induction of ring mitochondria. Mol Cell Neurosci 30:477-484.
    • (2005) Mol Cell Neurosci , vol.30 , pp. 477-484
    • Millar, J.K.1    James, R.2    Christie, S.3    Porteous, D.J.4
  • 19
    • 0033588176 scopus 로고    scopus 로고
    • Mice with reduced NMDA receptor expression display behaviors related to schizophrenia
    • Mohn AR, Gainetdinov RR, Caron MG, Koller BH 1999 Mice with reduced NMDA receptor expression display behaviors related to schizophrenia. Cell 98:427-436.
    • (1999) Cell , vol.98 , pp. 427-436
    • Mohn, A.R.1    Gainetdinov, R.R.2    Caron, M.G.3    Koller, B.H.4
  • 20
    • 0037422609 scopus 로고    scopus 로고
    • Disrupted-in-Schizophrenia-1 (DISC-1): mutant truncation prevents binding to NudE-like (NUDEL) and inhibits neurite outgrowth
    • Ozeki Y, Tomoda T, Kleiderlein J et al 2003 Disrupted-in-Schizophrenia-1 (DISC-1): mutant truncation prevents binding to NudE-like (NUDEL) and inhibits neurite outgrowth. Proc Natl Acad Sci USA 100:289-294.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 289-294
    • Ozeki, Y.1    Tomoda, T.2    Kleiderlein, J.3
  • 21
    • 33745712343 scopus 로고    scopus 로고
    • The genetics and biology of DISC1-an emerging role in psychosis and cognition
    • Porteous DJ, Thomson P, Brandon NJ, Millar JK 2006 The genetics and biology of DISC1-an emerging role in psychosis and cognition. Biol Psychiatry 60:123-131.
    • (2006) Biol Psychiatry , vol.60 , pp. 123-131
    • Porteous, D.J.1    Thomson, P.2    Brandon, N.J.3    Millar, J.K.4
  • 22
    • 13444306480 scopus 로고    scopus 로고
    • Transient N-methyl-D-aspartate receptor blockade in early development causes lasting cognitive deficits relevant to schizophrenia
    • Stefani MR, Moghaddam B 2005 Transient N-methyl-D-aspartate receptor blockade in early development causes lasting cognitive deficits relevant to schizophrenia. Biol Psychiatry 57:433-436.
    • (2005) Biol Psychiatry , vol.57 , pp. 433-436
    • Stefani, M.R.1    Moghaddam, B.2
  • 23
    • 2342512304 scopus 로고    scopus 로고
    • Dysbindin-1 is reduced in intrinsic, glutamatergic terminals of the hippocampal formation in schizophrenia
    • Talbot K, Eidem WL, Tinsley CL et al 2004 Dysbindin-1 is reduced in intrinsic, glutamatergic terminals of the hippocampal formation in schizophrenia. J Clin Invest 113:1353-1363.
    • (2004) J Clin Invest , vol.113 , pp. 1353-1363
    • Talbot, K.1    Eidem, W.L.2    Tinsley, C.L.3
  • 24
    • 33749563041 scopus 로고    scopus 로고
    • Dysbindin-1 is a synaptic and microtubular protein that binds brain snapin
    • Talbot K, Cho DS, Ong WY et al 2006 Dysbindin-1 is a synaptic and microtubular protein that binds brain snapin. Hum Mol Genet 15:3041-3054.
    • (2006) Hum Mol Genet , vol.15 , pp. 3041-3054
    • Talbot, K.1    Cho, D.S.2    Ong, W.Y.3
  • 25
    • 12344254627 scopus 로고    scopus 로고
    • Phenotype of schizophrenia: a review and formulation
    • Tamminga CA, Holcomb HH 2005 Phenotype of schizophrenia: a review and formulation. Mol Psychiatry 10:27-39.
    • (2005) Mol Psychiatry , vol.10 , pp. 27-39
    • Tamminga, C.A.1    Holcomb, H.H.2
  • 26
    • 33846149648 scopus 로고    scopus 로고
    • DISC1 regulates the transport of the NUDEL/LIS1/14-3-3epsilon complex through kinesin-1
    • Taya S, Shinoda T, Tsuboi D et al 2007 DISC1 regulates the transport of the NUDEL/LIS1/14-3-3epsilon complex through kinesin-1. J Neurosci 27:15-26.
    • (2007) J Neurosci , vol.27 , pp. 15-26
    • Taya, S.1    Shinoda, T.2    Tsuboi, D.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.