Inhibition of toll-like receptor-4, nuclear factor-κB and mitogen-activated protein kinase by lignocaine may involve voltage-sensitive sodium channels

Clinical and Experimental Pharmacology and Physiology

Volumn 35, Issue 9, 2008, Pages 1052-1058

  Lee, Ping Ying ^b   Tsai, Pei Shan ^b   Huang, Ya Hsien ^b   Huang, Chun Jen ^a,b,c  

^a MACKAY MEMORIAL HOSPITAL   (Taiwan)

^b TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^c TAIPEI MEDICAL UNIVERSITY   (Taiwan)

Author keywords

Lignocaine; Mitogen activated protein kinases; Nuclear factor B; Sodium channel; Toll like receptor

Indexed keywords

ACTIN; ENDOTOXIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; LIDOCAINE; LIPOPOLYSACCHARIDE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; SODIUM CHANNEL; STRESS ACTIVATED PROTEIN KINASE; TETRODOTOXIN; TOLL LIKE RECEPTOR 4; VERATRIDINE;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DRUG PROTEIN BINDING; DRUG RECEPTOR BINDING; MACROPHAGE ACTIVATION; MOUSE; NONHUMAN; PROTEIN EXPRESSION; SEPSIS; SYSTEMIC INFLAMMATORY RESPONSE SYNDROME; UPREGULATION;

ANESTHETICS, LOCAL; ANIMALS; CELLS, CULTURED; ENZYME ACTIVATION; LIDOCAINE; LIPOPOLYSACCHARIDES; MICE; MITOGEN-ACTIVATED PROTEIN KINASES; NF-KAPPA B; SODIUM CHANNELS; TETRODOTOXIN; TOLL-LIKE RECEPTOR 4;

EID: 48749125890     PISSN: 03051870     EISSN: 14401681     Source Type: Journal    
DOI: 10.1111/j.1440-1681.2008.04962.x     Document Type: Article

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