Force-based Analysis of Multidimensional Energy Landscapes: Application of Dynamic Force Spectroscopy and Steered Molecular Dynamics Simulations to an Antibody Fragment-Peptide Complex

Journal of Molecular Biology

Volumn 381, Issue 5, 2008, Pages 1253-1266

  Morfill, Julia ^a   Neumann, Jan ^a   Blank, Kerstin ^a   Steinbach, Uta ^a   Puchner, Elias M ^a   Gottschalk, Kay E ^a   Gaub, Hermann E ^a  

^a UNIVERSITY OF MUNICH   (Germany)

Author keywords

antibody antigen interaction; atomic force microscope; energy landscape; molecular dynamics simulations; single molecule force spectroscopy

Indexed keywords

PEPTIDE DERIVATIVE; SINGLE CHAIN FRAGMENT VARIABLE ANTIBODY;

ANTIGEN ANTIBODY COMPLEX; ANTIGEN ANTIBODY REACTION; ARTICLE; ATOMIC FORCE MICROSCOPY; DISSOCIATION CONSTANT; HYDROGEN BOND; MOLECULAR DYNAMICS; PEPTIDE ANALYSIS; PRIORITY JOURNAL; SIMULATION; SPECTROSCOPY; SURFACE PLASMON RESONANCE;

EID: 48749094946     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmb.2008.06.065     Document Type: Article

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