Dynamic single-molecule force spectroscopy: Bond rupture analysis with variable spacer length

Journal of Physics Condensed Matter

Volumn 15, Issue 18, 2003, Pages

  Friedsam, Claudia ^a   Wehle, Angelika K ^a   Kühner, Ferdinand ^a   Gaub, Hermann E ^a  

^a UNIVERSITY OF MUNICH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

DISSOCIATION; ERROR ANALYSIS; MONTE CARLO METHODS; PROBABILITY DENSITY FUNCTION; SPECTROSCOPIC ANALYSIS;

DYNAMIC FORCE SPECTROSCOPY;

POLYMERS;

EID: 0037621477     PISSN: 09538984     EISSN: None     Source Type: Journal    
DOI: 10.1088/0953-8984/15/18/305     Document Type: Conference Paper

References (43)

1. Bell G I 1978 Science 200 618-27
2. Evans E, Berk D and Leung A 1991 Biophys. J. 59 838-48
3. Evans E and Ritchie K 1997 Biophys. J. 72 1541-55 Israilev S, Stepaniants S, Balsera M, Ono Y and Schulten K 1997 Biophys. J. 72 1568-81 Grubmüller H, Heymann B and Tavan P 1996 Science 271 997-9
4. Evans E and Ritchie K 1997 Biophys. J. 72 1541-55 Israilev S, Stepaniants S, Balsera M, Ono Y and Schulten K 1997 Biophys. J. 72 1568-81 Grubmüller H, Heymann B and Tavan P 1996 Science 271 997-9
5. Evans E and Ritchie K 1997 Biophys. J. 72 1541-55 Israilev S, Stepaniants S, Balsera M, Ono Y and Schulten K 1997 Biophys. J. 72 1568-81 Grubmüller H, Heymann B and Tavan P 1996 Science 271 997-9
6. Rief M, Oesterhelt F, Heymann B and Gaub H E 1997 Science 275 1295-7 Grandbois M, Beyer M, Rief M, Clausen-Schaumann H and Gaub H E 1999 Science 283 1727-30 Rief M, Pascual J. Saraste M and Gaub H E 1999 J. Mol. Biol. 286 553-61 Merkel R, Nassoy P, Leung A, Ritchie K and Evans E 1999 Nature 397 50-3 Strunz T, Oroszlan K, Shafer R and Gutherodt H-J 1999 Proc. Natl Acad. Sci. USA 96 11277-82 Dammer U, Hegner M, Anselmetti D, Wagner P, Dreier M, Huber W and Güntherodt H-J 1996 Biophys. J. 70 2437-41 Dettmann W, Grandbois M, André S, Benoit M, Wehle A, Kaltner H, Gabius H-J and Gaub H E 2000 Arch. Biochem. Biophys. 383 157-70 Evans E and Ludwig F 2000 Phys. Condens. Malter A 12 315-20 Krüger D, Fuchs H, Rousseau R, Marx D and Parrinello M 2002 Phys. Rev. Lett. 89 186402-(1-4) Allemand J-F, Bensimon D, Jullien L, Bensimon A and Croquette V Biophys. J. 73 2064-70 Thomson N H, Fritz M, Radmacher M, Schmidt C F and Hansma P K 1996 Biophys. J. 70 2421-31
7. Rief M, Oesterhelt F, Heymann B and Gaub H E 1997 Science 275 1295-7 Grandbois M, Beyer M, Rief M, Clausen-Schaumann H and Gaub H E 1999 Science 283 1727-30 Rief M, Pascual J. Saraste M and Gaub H E 1999 J. Mol. Biol. 286 553-61 Merkel R, Nassoy P, Leung A, Ritchie K and Evans E 1999 Nature 397 50-3 Strunz T, Oroszlan K, Shafer R and Gutherodt H-J 1999 Proc. Natl Acad. Sci. USA 96 11277-82 Dammer U, Hegner M, Anselmetti D, Wagner P, Dreier M, Huber W and Güntherodt H-J 1996 Biophys. J. 70 2437-41 Dettmann W, Grandbois M, André S, Benoit M, Wehle A, Kaltner H, Gabius H-J and Gaub H E 2000 Arch. Biochem. Biophys. 383 157-70 Evans E and Ludwig F 2000 Phys. Condens. Malter A 12 315-20 Krüger D, Fuchs H, Rousseau R, Marx D and Parrinello M 2002 Phys. Rev. Lett. 89 186402-(1-4) Allemand J-F, Bensimon D, Jullien L, Bensimon A and Croquette V Biophys. J. 73 2064-70 Thomson N H, Fritz M, Radmacher M, Schmidt C F and Hansma P K 1996 Biophys. J. 70 2421-31
8. Rief M, Oesterhelt F, Heymann B and Gaub H E 1997 Science 275 1295-7 Grandbois M, Beyer M, Rief M, Clausen-Schaumann H and Gaub H E 1999 Science 283 1727-30 Rief M, Pascual J. Saraste M and Gaub H E 1999 J. Mol. Biol. 286 553-61 Merkel R, Nassoy P, Leung A, Ritchie K and Evans E 1999 Nature 397 50-3 Strunz T, Oroszlan K, Shafer R and Gutherodt H-J 1999 Proc. Natl Acad. Sci. USA 96 11277-82 Dammer U, Hegner M, Anselmetti D, Wagner P, Dreier M, Huber W and Güntherodt H-J 1996 Biophys. J. 70 2437-41 Dettmann W, Grandbois M, André S, Benoit M, Wehle A, Kaltner H, Gabius H-J and Gaub H E 2000 Arch. Biochem. Biophys. 383 157-70 Evans E and Ludwig F 2000 Phys. Condens. Malter A 12 315-20 Krüger D, Fuchs H, Rousseau R, Marx D and Parrinello M 2002 Phys. Rev. Lett. 89 186402-(1-4) Allemand J-F, Bensimon D, Jullien L, Bensimon A and Croquette V Biophys. J. 73 2064-70 Thomson N H, Fritz M, Radmacher M, Schmidt C F and Hansma P K 1996 Biophys. J. 70 2421-31
9. Rief M, Oesterhelt F, Heymann B and Gaub H E 1997 Science 275 1295-7 Grandbois M, Beyer M, Rief M, Clausen-Schaumann H and Gaub H E 1999 Science 283 1727-30 Rief M, Pascual J. Saraste M and Gaub H E 1999 J. Mol. Biol. 286 553-61 Merkel R, Nassoy P, Leung A, Ritchie K and Evans E 1999 Nature 397 50-3 Strunz T, Oroszlan K, Shafer R and Gutherodt H-J 1999 Proc. Natl Acad. Sci. USA 96 11277-82 Dammer U, Hegner M, Anselmetti D, Wagner P, Dreier M, Huber W and Güntherodt H-J 1996 Biophys. J. 70 2437-41 Dettmann W, Grandbois M, André S, Benoit M, Wehle A, Kaltner H, Gabius H-J and Gaub H E 2000 Arch. Biochem. Biophys. 383 157-70 Evans E and Ludwig F 2000 Phys. Condens. Malter A 12 315-20 Krüger D, Fuchs H, Rousseau R, Marx D and Parrinello M 2002 Phys. Rev. Lett. 89 186402-(1-4) Allemand J-F, Bensimon D, Jullien L, Bensimon A and Croquette V Biophys. J. 73 2064-70 Thomson N H, Fritz M, Radmacher M, Schmidt C F and Hansma P K 1996 Biophys. J. 70 2421-31
10. Rief M, Oesterhelt F, Heymann B and Gaub H E 1997 Science 275 1295-7 Grandbois M, Beyer M, Rief M, Clausen-Schaumann H and Gaub H E 1999 Science 283 1727-30 Rief M, Pascual J. Saraste M and Gaub H E 1999 J. Mol. Biol. 286 553-61 Merkel R, Nassoy P, Leung A, Ritchie K and Evans E 1999 Nature 397 50-3 Strunz T, Oroszlan K, Shafer R and Gutherodt H-J 1999 Proc. Natl Acad. Sci. USA 96 11277-82 Dammer U, Hegner M, Anselmetti D, Wagner P, Dreier M, Huber W and Güntherodt H-J 1996 Biophys. J. 70 2437-41 Dettmann W, Grandbois M, André S, Benoit M, Wehle A, Kaltner H, Gabius H-J and Gaub H E 2000 Arch. Biochem. Biophys. 383 157-70 Evans E and Ludwig F 2000 Phys. Condens. Malter A 12 315-20 Krüger D, Fuchs H, Rousseau R, Marx D and Parrinello M 2002 Phys. Rev. Lett. 89 186402-(1-4) Allemand J-F, Bensimon D, Jullien L, Bensimon A and Croquette V Biophys. J. 73 2064-70 Thomson N H, Fritz M, Radmacher M, Schmidt C F and Hansma P K 1996 Biophys. J. 70 2421-31
11. Rief M, Oesterhelt F, Heymann B and Gaub H E 1997 Science 275 1295-7 Grandbois M, Beyer M, Rief M, Clausen-Schaumann H and Gaub H E 1999 Science 283 1727-30 Rief M, Pascual J. Saraste M and Gaub H E 1999 J. Mol. Biol. 286 553-61 Merkel R, Nassoy P, Leung A, Ritchie K and Evans E 1999 Nature 397 50-3 Strunz T, Oroszlan K, Shafer R and Gutherodt H-J 1999 Proc. Natl Acad. Sci. USA 96 11277-82 Dammer U, Hegner M, Anselmetti D, Wagner P, Dreier M, Huber W and Güntherodt H-J 1996 Biophys. J. 70 2437-41 Dettmann W, Grandbois M, André S, Benoit M, Wehle A, Kaltner H, Gabius H-J and Gaub H E 2000 Arch. Biochem. Biophys. 383 157-70 Evans E and Ludwig F 2000 Phys. Condens. Malter A 12 315-20 Krüger D, Fuchs H, Rousseau R, Marx D and Parrinello M 2002 Phys. Rev. Lett. 89 186402-(1-4) Allemand J-F, Bensimon D, Jullien L, Bensimon A and Croquette V Biophys. J. 73 2064-70 Thomson N H, Fritz M, Radmacher M, Schmidt C F and Hansma P K 1996 Biophys. J. 70 2421-31
12. Rief M, Oesterhelt F, Heymann B and Gaub H E 1997 Science 275 1295-7 Grandbois M, Beyer M, Rief M, Clausen-Schaumann H and Gaub H E 1999 Science 283 1727-30 Rief M, Pascual J. Saraste M and Gaub H E 1999 J. Mol. Biol. 286 553-61 Merkel R, Nassoy P, Leung A, Ritchie K and Evans E 1999 Nature 397 50-3 Strunz T, Oroszlan K, Shafer R and Gutherodt H-J 1999 Proc. Natl Acad. Sci. USA 96 11277-82 Dammer U, Hegner M, Anselmetti D, Wagner P, Dreier M, Huber W and Güntherodt H-J 1996 Biophys. J. 70 2437-41 Dettmann W, Grandbois M, André S, Benoit M, Wehle A, Kaltner H, Gabius H-J and Gaub H E 2000 Arch. Biochem. Biophys. 383 157-70 Evans E and Ludwig F 2000 Phys. Condens. Malter A 12 315-20 Krüger D, Fuchs H, Rousseau R, Marx D and Parrinello M 2002 Phys. Rev. Lett. 89 186402-(1-4) Allemand J-F, Bensimon D, Jullien L, Bensimon A and Croquette V Biophys. J. 73 2064-70 Thomson N H, Fritz M, Radmacher M, Schmidt C F and Hansma P K 1996 Biophys. J. 70 2421-31
13. Rief M, Oesterhelt F, Heymann B and Gaub H E 1997 Science 275 1295-7 Grandbois M, Beyer M, Rief M, Clausen-Schaumann H and Gaub H E 1999 Science 283 1727-30 Rief M, Pascual J. Saraste M and Gaub H E 1999 J. Mol. Biol. 286 553-61 Merkel R, Nassoy P, Leung A, Ritchie K and Evans E 1999 Nature 397 50-3 Strunz T, Oroszlan K, Shafer R and Gutherodt H-J 1999 Proc. Natl Acad. Sci. USA 96 11277-82 Dammer U, Hegner M, Anselmetti D, Wagner P, Dreier M, Huber W and Güntherodt H-J 1996 Biophys. J. 70 2437-41 Dettmann W, Grandbois M, André S, Benoit M, Wehle A, Kaltner H, Gabius H-J and Gaub H E 2000 Arch. Biochem. Biophys. 383 157-70 Evans E and Ludwig F 2000 Phys. Condens. Malter A 12 315-20 Krüger D, Fuchs H, Rousseau R, Marx D and Parrinello M 2002 Phys. Rev. Lett. 89 186402-(1-4) Allemand J-F, Bensimon D, Jullien L, Bensimon A and Croquette V Biophys. J. 73 2064-70 Thomson N H, Fritz M, Radmacher M, Schmidt C F and Hansma P K 1996 Biophys. J. 70 2421-31
14. Rief M, Oesterhelt F, Heymann B and Gaub H E 1997 Science 275 1295-7 Grandbois M, Beyer M, Rief M, Clausen-Schaumann H and Gaub H E 1999 Science 283 1727-30 Rief M, Pascual J. Saraste M and Gaub H E 1999 J. Mol. Biol. 286 553-61 Merkel R, Nassoy P, Leung A, Ritchie K and Evans E 1999 Nature 397 50-3 Strunz T, Oroszlan K, Shafer R and Gutherodt H-J 1999 Proc. Natl Acad. Sci. USA 96 11277-82 Dammer U, Hegner M, Anselmetti D, Wagner P, Dreier M, Huber W and Güntherodt H-J 1996 Biophys. J. 70 2437-41 Dettmann W, Grandbois M, André S, Benoit M, Wehle A, Kaltner H, Gabius H-J and Gaub H E 2000 Arch. Biochem. Biophys. 383 157-70 Evans E and Ludwig F 2000 Phys. Condens. Malter A 12 315-20 Krüger D, Fuchs H, Rousseau R, Marx D and Parrinello M 2002 Phys. Rev. Lett. 89 186402-(1-4) Allemand J-F, Bensimon D, Jullien L, Bensimon A and Croquette V Biophys. J. 73 2064-70 Thomson N H, Fritz M, Radmacher M, Schmidt C F and Hansma P K 1996 Biophys. J. 70 2421-31
15. Rief M, Oesterhelt F, Heymann B and Gaub H E 1997 Science 275 1295-7 Grandbois M, Beyer M, Rief M, Clausen-Schaumann H and Gaub H E 1999 Science 283 1727-30 Rief M, Pascual J. Saraste M and Gaub H E 1999 J. Mol. Biol. 286 553-61 Merkel R, Nassoy P, Leung A, Ritchie K and Evans E 1999 Nature 397 50-3 Strunz T, Oroszlan K, Shafer R and Gutherodt H-J 1999 Proc. Natl Acad. Sci. USA 96 11277-82 Dammer U, Hegner M, Anselmetti D, Wagner P, Dreier M, Huber W and Güntherodt H-J 1996 Biophys. J. 70 2437-41 Dettmann W, Grandbois M, André S, Benoit M, Wehle A, Kaltner H, Gabius H-J and Gaub H E 2000 Arch. Biochem. Biophys. 383 157-70 Evans E and Ludwig F 2000 Phys. Condens. Malter A 12 315-20 Krüger D, Fuchs H, Rousseau R, Marx D and Parrinello M 2002 Phys. Rev. Lett. 89 186402-(1-4) Allemand J-F, Bensimon D, Jullien L, Bensimon A and Croquette V Biophys. J. 73 2064-70 Thomson N H, Fritz M, Radmacher M, Schmidt C F and Hansma P K 1996 Biophys. J. 70 2421-31
16. Rief M, Oesterhelt F, Heymann B and Gaub H E 1997 Science 275 1295-7 Grandbois M, Beyer M, Rief M, Clausen-Schaumann H and Gaub H E 1999 Science 283 1727-30 Rief M, Pascual J. Saraste M and Gaub H E 1999 J. Mol. Biol. 286 553-61 Merkel R, Nassoy P, Leung A, Ritchie K and Evans E 1999 Nature 397 50-3 Strunz T, Oroszlan K, Shafer R and Gutherodt H-J 1999 Proc. Natl Acad. Sci. USA 96 11277-82 Dammer U, Hegner M, Anselmetti D, Wagner P, Dreier M, Huber W and Güntherodt H-J 1996 Biophys. J. 70 2437-41 Dettmann W, Grandbois M, André S, Benoit M, Wehle A, Kaltner H, Gabius H-J and Gaub H E 2000 Arch. Biochem. Biophys. 383 157-70 Evans E and Ludwig F 2000 Phys. Condens. Malter A 12 315-20 Krüger D, Fuchs H, Rousseau R, Marx D and Parrinello M 2002 Phys. Rev. Lett. 89 186402-(1-4) Allemand J-F, Bensimon D, Jullien L, Bensimon A and Croquette V Biophys. J. 73 2064-70 Thomson N H, Fritz M, Radmacher M, Schmidt C F and Hansma P K 1996 Biophys. J. 70 2421-31
17. Evans E and Ritchie K 1999 Biophys. J. 76 2439-47
18. Evans E 2001 Annu. Rev. Biomol. Struct. 30 105-28 Evans E 1999 Biophys. Chem. 82 83-97 Evans E 1998 Faraday Discuss. 111 1-16 Heymann B and Grubmüller H 2000 Phys. Rev. Lett. 84 6126-9 Heymann B and Grubmüller H 2001 Biophys. J. 81 1295-313 Heymann B and Grubmüller H 1999 Chem. Phys. Lett. 303 1-9 Balsera M, Stepaniants S, Israilev S, Oono Y and Schulten K J 1997 Biophys. J. 73 1281-7 Boresch S and Karplus M 1995 J. Mol. Biol 254 801 Shillcock J and Seifert U 1998 Phys. Rev. E 57 7301-4 Seifert U 2000 Phys. Rev. Lett. 84 2750-3
19. Evans E 2001 Annu. Rev. Biomol. Struct. 30 105-28 Evans E 1999 Biophys. Chem. 82 83-97 Evans E 1998 Faraday Discuss. 111 1-16 Heymann B and Grubmüller H 2000 Phys. Rev. Lett. 84 6126-9 Heymann B and Grubmüller H 2001 Biophys. J. 81 1295-313 Heymann B and Grubmüller H 1999 Chem. Phys. Lett. 303 1-9 Balsera M, Stepaniants S, Israilev S, Oono Y and Schulten K J 1997 Biophys. J. 73 1281-7 Boresch S and Karplus M 1995 J. Mol. Biol 254 801 Shillcock J and Seifert U 1998 Phys. Rev. E 57 7301-4 Seifert U 2000 Phys. Rev. Lett. 84 2750-3
20. Evans E 2001 Annu. Rev. Biomol. Struct. 30 105-28 Evans E 1999 Biophys. Chem. 82 83-97 Evans E 1998 Faraday Discuss. 111 1-16 Heymann B and Grubmüller H 2000 Phys. Rev. Lett. 84 6126-9 Heymann B and Grubmüller H 2001 Biophys. J. 81 1295-313 Heymann B and Grubmüller H 1999 Chem. Phys. Lett. 303 1-9 Balsera M, Stepaniants S, Israilev S, Oono Y and Schulten K J 1997 Biophys. J. 73 1281-7 Boresch S and Karplus M 1995 J. Mol. Biol 254 801 Shillcock J and Seifert U 1998 Phys. Rev. E 57 7301-4 Seifert U 2000 Phys. Rev. Lett. 84 2750-3
21. Evans E 2001 Annu. Rev. Biomol. Struct. 30 105-28 Evans E 1999 Biophys. Chem. 82 83-97 Evans E 1998 Faraday Discuss. 111 1-16 Heymann B and Grubmüller H 2000 Phys. Rev. Lett. 84 6126-9 Heymann B and Grubmüller H 2001 Biophys. J. 81 1295-313 Heymann B and Grubmüller H 1999 Chem. Phys. Lett. 303 1-9 Balsera M, Stepaniants S, Israilev S, Oono Y and Schulten K J 1997 Biophys. J. 73 1281-7 Boresch S and Karplus M 1995 J. Mol. Biol 254 801 Shillcock J and Seifert U 1998 Phys. Rev. E 57 7301-4 Seifert U 2000 Phys. Rev. Lett. 84 2750-3
22. Evans E 2001 Annu. Rev. Biomol. Struct. 30 105-28 Evans E 1999 Biophys. Chem. 82 83-97 Evans E 1998 Faraday Discuss. 111 1-16 Heymann B and Grubmüller H 2000 Phys. Rev. Lett. 84 6126-9 Heymann B and Grubmüller H 2001 Biophys. J. 81 1295-313 Heymann B and Grubmüller H 1999 Chem. Phys. Lett. 303 1-9 Balsera M, Stepaniants S, Israilev S, Oono Y and Schulten K J 1997 Biophys. J. 73 1281-7 Boresch S and Karplus M 1995 J. Mol. Biol 254 801 Shillcock J and Seifert U 1998 Phys. Rev. E 57 7301-4 Seifert U 2000 Phys. Rev. Lett. 84 2750-3
23. Evans E 2001 Annu. Rev. Biomol. Struct. 30 105-28 Evans E 1999 Biophys. Chem. 82 83-97 Evans E 1998 Faraday Discuss. 111 1-16 Heymann B and Grubmüller H 2000 Phys. Rev. Lett. 84 6126-9 Heymann B and Grubmüller H 2001 Biophys. J. 81 1295-313 Heymann B and Grubmüller H 1999 Chem. Phys. Lett. 303 1-9 Balsera M, Stepaniants S, Israilev S, Oono Y and Schulten K J 1997 Biophys. J. 73 1281-7 Boresch S and Karplus M 1995 J. Mol. Biol 254 801 Shillcock J and Seifert U 1998 Phys. Rev. E 57 7301-4 Seifert U 2000 Phys. Rev. Lett. 84 2750-3
24. Evans E 2001 Annu. Rev. Biomol. Struct. 30 105-28 Evans E 1999 Biophys. Chem. 82 83-97 Evans E 1998 Faraday Discuss. 111 1-16 Heymann B and Grubmüller H 2000 Phys. Rev. Lett. 84 6126-9 Heymann B and Grubmüller H 2001 Biophys. J. 81 1295-313 Heymann B and Grubmüller H 1999 Chem. Phys. Lett. 303 1-9 Balsera M, Stepaniants S, Israilev S, Oono Y and Schulten K J 1997 Biophys. J. 73 1281-7 Boresch S and Karplus M 1995 J. Mol. Biol 254 801 Shillcock J and Seifert U 1998 Phys. Rev. E 57 7301-4 Seifert U 2000 Phys. Rev. Lett. 84 2750-3
25. Evans E 2001 Annu. Rev. Biomol. Struct. 30 105-28 Evans E 1999 Biophys. Chem. 82 83-97 Evans E 1998 Faraday Discuss. 111 1-16 Heymann B and Grubmüller H 2000 Phys. Rev. Lett. 84 6126-9 Heymann B and Grubmüller H 2001 Biophys. J. 81 1295-313 Heymann B and Grubmüller H 1999 Chem. Phys. Lett. 303 1-9 Balsera M, Stepaniants S, Israilev S, Oono Y and Schulten K J 1997 Biophys. J. 73 1281-7 Boresch S and Karplus M 1995 J. Mol. Biol 254 801 Shillcock J and Seifert U 1998 Phys. Rev. E 57 7301-4 Seifert U 2000 Phys. Rev. Lett. 84 2750-3
26. Evans E 2001 Annu. Rev. Biomol. Struct. 30 105-28 Evans E 1999 Biophys. Chem. 82 83-97 Evans E 1998 Faraday Discuss. 111 1-16 Heymann B and Grubmüller H 2000 Phys. Rev. Lett. 84 6126-9 Heymann B and Grubmüller H 2001 Biophys. J. 81 1295-313 Heymann B and Grubmüller H 1999 Chem. Phys. Lett. 303 1-9 Balsera M, Stepaniants S, Israilev S, Oono Y and Schulten K J 1997 Biophys. J. 73 1281-7 Boresch S and Karplus M 1995 J. Mol. Biol 254 801 Shillcock J and Seifert U 1998 Phys. Rev. E 57 7301-4 Seifert U 2000 Phys. Rev. Lett. 84 2750-3
27. Evans E 2001 Annu. Rev. Biomol. Struct. 30 105-28 Evans E 1999 Biophys. Chem. 82 83-97 Evans E 1998 Faraday Discuss. 111 1-16 Heymann B and Grubmüller H 2000 Phys. Rev. Lett. 84 6126-9 Heymann B and Grubmüller H 2001 Biophys. J. 81 1295-313 Heymann B and Grubmüller H 1999 Chem. Phys. Lett. 303 1-9 Balsera M, Stepaniants S, Israilev S, Oono Y and Schulten K J 1997 Biophys. J. 73 1281-7 Boresch S and Karplus M 1995 J. Mol. Biol 254 801 Shillcock J and Seifert U 1998 Phys. Rev. E 57 7301-4 Seifert U 2000 Phys. Rev. Lett. 84 2750-3
28. Arrhenius S 1889 Z. Phys. Chem. Lpz. 4 226 Van't Hoff J H 1884 Etudes de Dynamiques Chimiques (Amsterdam: Muller) p 114
29. Arrhenius S 1889 Z. Phys. Chem. Lpz. 4 226 Van't Hoff J H 1884 Etudes de Dynamiques Chimiques (Amsterdam: Muller) p 114
30. Kramers H A 1940 Physica (Utrecht) 7 284 Hänggi P, Talkner P and Borkovec M 1990 Rev. Mod. Phys. 62
31. Kramers H A 1940 Physica (Utrecht) 7 284 Hänggi P, Talkner P and Borkovec M 1990 Rev. Mod. Phys. 62
32. Rief M, Oautel M, Oesterhelt F, Femandez J M and Gaub H E 1997 Science 275 1295-8 Smith S B, Cui Y and Bustamante C 1996 Science 271 795-8
33. Rief M, Oautel M, Oesterhelt F, Femandez J M and Gaub H E 1997 Science 275 1295-8 Smith S B, Cui Y and Bustamante C 1996 Science 271 795-8
34. In the meantime there are alternative polymer models: Livadaru L, Netz R R and Kreuzer H J 2003 J. Chem. Phys. 118 1404 Netz R R and Andelman D 2002 Encyclopedia of Electrochemistry ed M Urbakh and E Giladi (New York Wiley - VCH) Fleck C. Netz R R and von Grünberg H H 2002 Biophys. J. 82 76
35. In the meantime there are alternative polymer models: Livadaru L, Netz R R and Kreuzer H J 2003 J. Chem. Phys. 118 1404 Netz R R and Andelman D 2002 Encyclopedia of Electrochemistry ed M Urbakh and E Giladi (New York Wiley - VCH) Fleck C. Netz R R and von Grünberg H H 2002 Biophys. J. 82 76
36. In the meantime there are alternative polymer models: Livadaru L, Netz R R and Kreuzer H J 2003 J. Chem. Phys. 118 1404 Netz R R and Andelman D 2002 Encyclopedia of Electrochemistry ed M Urbakh and E Giladi (New York Wiley - VCH) Fleck C. Netz R R and von Grünberg H H 2002 Biophys. J. 82 76
37. Cluzel P, Lebrun A, Heller C, Lavery R, Vivoy J-L, Chateny D and Caron F 1996 Science 271 792-4 Rief M. Fernandez J M and Gaub H E 1998 Phys. Rev. Lett. 81 4764-7
38. Cluzel P, Lebrun A, Heller C, Lavery R, Vivoy J-L, Chateny D and Caron F 1996 Science 271 792-4 Rief M. Fernandez J M and Gaub H E 1998 Phys. Rev. Lett. 81 4764-7
39. Oesterhelt F, Rief M and Gaub H E 1999 New J. Phys. 1 6.1-6.11 Tadokoro H 1990 Structure of Crystalline Polymers (Malabar, FL: Krieger)
40. Oesterhelt F, Rief M and Gaub H E 1999 New J. Phys. 1 6.1-6.11 Tadokoro H 1990 Structure of Crystalline Polymers (Malabar, FL: Krieger)
41. James W 2000 Encyclopedia of Analytical Chemistry ed R A Meyers pp 4848-71
42. Wiegand T W, Williams P B and Dreskin S C 1996 J. Immunol. 157 221-30
43. Liss M, Petersen B, Wolf H and Prohaska E 2002 Anal. Chem. 74 4488-95