Effects of selective serotonin2 ligands on behaviors evoked by stress in the rat

Pharmacology Biochemistry and Behavior

Volumn 90, Issue 4, 2008, Pages 632-639

  Hawkins, Mike F ^a   Uzelac, Sarah M ^a   Hearn, John K ^a   Baumeister, Alan A ^a  

^a LOUISIANA STATE UNIVERSITY   (United States)

Author keywords

DOI; Ketanserin; Open field; SDZ SER 082; Serotonin agonist; Serotonin antagonist; Serotonin 2 receptor; Spiperone; Stress; Tail pinch

Indexed keywords

4 IODO 2,5 DIMETHOXYAMPHETAMINE; 4,5,7A,8,9,10,11,11A OCTAHYDRO 10 METHYL 7H INDOLO[1,7 BC][2,6]NAPHTHYRIDINE; KETANSERIN; RECEPTOR SUBTYPE; SEROTONIN 2A AGONIST; SEROTONIN 2A RECEPTOR; SEROTONIN 2C AGONIST; SEROTONIN 2C RECEPTOR; SPIPERONE; DOPAMINE RECEPTOR BLOCKING AGENT; SEROTONIN 2 RECEPTOR; SEROTONIN AGONIST; SEROTONIN ANTAGONIST;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ARTICLE; BODY POSTURE; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; DRUG MECHANISM; DRUG RECEPTOR BINDING; DRUG SELECTIVITY; FEEDING BEHAVIOR; HEAD MOVEMENT; ILLUMINATION; MALE; NONHUMAN; OPEN FIELD TEST; PINCH STRENGTH; PRIORITY JOURNAL; RAT; REARING; RECEPTOR AFFINITY; STRESS; VOCALIZATION; ANIMAL; BODY EQUILIBRIUM; DRUG ANTAGONISM; DRUG POTENTIATION; MENTAL STRESS; MOTOR ACTIVITY; PAIN ASSESSMENT; PSYCHOLOGICAL ASPECT; SPRAGUE DAWLEY RAT;

RATTUS;

ANIMALS; BEHAVIOR, ANIMAL; DOPAMINE ANTAGONISTS; DOSE-RESPONSE RELATIONSHIP, DRUG; KETANSERIN; MALE; MOTOR ACTIVITY; PAIN MEASUREMENT; POSTURAL BALANCE; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, SEROTONIN, 5-HT2; SEROTONIN AGONISTS; SEROTONIN ANTAGONISTS; SPIPERONE; STRESS, PSYCHOLOGICAL; VOCALIZATION, ANIMAL;

EID: 48749092620     PISSN: 00913057     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pbb.2008.05.006     Document Type: Article

References (72)

1. Antelman S.M., and Szechtman H. Tail pinch induces eating in sated rats which appears to depend on nigrostriatal dopamine. Science 189 (1975) 731-733
2. 2A receptors regulate sympathetic nerves constricting the cutaneous vascular bed in rabbits and rats. Neuroscience 117 (2003) 939-948
3. Boess F.G., and Martin I.L. Molecular biology of 5-HT receptors. Neuropharmacology 33 3-4 (1994) 275-317
4. Bogeso K.P., Arnt J., Boeck V., Christensen A.V., Hyttel J., and Jensen K.G. Antihypertensive activity in a series of 1-piperazino-3-phenylindans with potent 5-HT2-antagonistic activity. J Med Chem 31 12 (1988) 2247-2256
5. 2A/2C receptor mechanism as shown by ketanserin: 24-h follow-up studies. Prog Neuro-Psychopharmacol Biol Psychiatry 28 (2004) 547-557
6. Brotto L.A., Gorzalka B.B., and Hanson L.A. Effects of housing conditions and 5-HT2A activation on male rat sexual behavior. Physiol Behav 63 (1998) 475-479
7. 2A receptor responsivity. Neuropharmacology 46 (2004) 202-210
8. Chaouloff F., Baudrie V., and Coupry I. Effects of chlorisondamine and restraint on cortical [3H]ketanserin binding, 5-HT2A receptor-mediated head shakes, and behaviours in models of anxiety. Neuropharmacology 33 (1994) 449-456
9. Cornwell-Jones C.A., Palfai T., Krasenbaum D., Byer Jr. E., Clark R., and Kinnard K. Housing influences exploration and social interaction of control and DSP-4-treated rats. Physiol Behav 52 2 (1992) 271-276
10. G-nitro-l-arginine methyl ester reduces stress-related feeding in the rat tail-pinch model. Pharmacol Biochem Behav 60 1 (1998) 91-96
11. Darmani N.A., Shaddy J., and Gerdes C.F. Differential ontogenesis of three DOI-induced behaviors in mice. Physiol Behav 60 (1996) 1495-1500
12. 2C receptor activation. Pharmacol Biochem Behav 72 1-2 (2002) 371-378
13. de Paula Soares V., and Zangrossi Jr. H. Involvement of 5-HT1A and 5-HT2 receptors of the dorsal periaqueductal gray in the regulation of the defensive behaviors generated by the elevated T-maze. Brain Res Bull 64 2 (2004) 181-188
14. De Vry J., Benz U., Schreiber R., and Traber J. Shock-induced ultrasonic vocalization in young adult rats: a model for testing putative anti-anxiety drugs. Eur J Pharmacol 249 (1993) 331-339
15. Dielenberg R.A., and McGregor I.S. Defensive behavior in rats towards predatory odors: a review. Neurosci Biobehav Rev 25 7-8 (2001) 597-609
16. Dursun S.M., and Handley S.L. Similarities in the pharmacology of spontaneous and DOI-induced head-shakes suggest 5HT2A receptors are active under physiological conditions. Psychopharmacology (Berl) 128 2 (1996) 198-205
17. Duxon M.S., Kennett G.A., Lightowler S., Blackburn T.P., and Fone K.C. Activation of 5-HT2B receptors in the medial amygdala causes anxiolysis in the social interaction test in the rat. Neuropharmacology 36 4-5 (1997) 601-608
18. Fantegrossi W.E., Murnane K.S., and Reissig C.J. The behavioral pharmacology of hallucinogens. Biochem Pharmacol 75 (2008) 17-33
19. 2 receptor subtypes to the hyperlocomotor effects of cocaine: Acute and chronic pharmacological analyses. J Pharmacol Exp Ther 310 3 (2004) 1246-1254
20. Fray P.J., Koob G.F., and Iversen S.D. Tail-pinch-elicited behavior in rats: preference, plasticity, and learning. Behav Neural Biol 36 (1982) 108-125
21. Ghoneim O.M., Legerea J.A., Golbraikha A., Tropsha A., and Booth R.G. Novel ligands for the human histamine H1 receptor: synthesis, pharmacology, and comparative molecular field analysis studies of 2-dimethylamino-5-(6)-phenyl-1,2,3,4-tetrahydronaphthalenes. Bio Med Chem 14 (2006) 6640-6658
22. Giorgi O., Lecca D., Piras G., Driscoll P., and Corda M.G. Dissociation between mesocortical dopamine release and fear-related behaviours in two psychogenetically selected lines of rats that differ in coping strategies to aversive conditions. Eur J Neurosci 17 (2003) 2716-2726
23. Granoff M.I., and Ashby Jr. C.R. The effect of the repeated administration of the compound 3,4-methylenedioxymethamphetamine on the response of rats to the 5-HT2A,C receptor agonist (+/-)-1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (DOI). Neuropsychobiology 37 (1998) 36-40
24. Glusa E., and Pertz H.H. Further evidence that 5-HT induced relaxation of pig pulmonary artery is mediated by endothelial 5-HT(2B) receptors. Br J Pharmacol 130 3 (2000) 692-698
25. Griebel G., Perrault G., and Sanger D.J. A comparative study of the effects of selective and non-selective 5-HT2 receptor subtype antagonists in rat and mouse models of anxiety. Neuropharmacology 36 6 (1997) 793-802
26. Hawkins M.F., Uzelac S.U., Baumeister A.A., Hearn J.K., Broussard J.I., and Guillot T.S. Behavioral responses to stress following central and peripheral injection of the 5-HT(2) agonist DOI. Pharmacol Biochem Behav 73 3 (2002) 537-544
27. Hoyer D., Clarke D.E., Fozrd J.R., Hartig P.R., Martin G.R., Mylecharane E.J., et al. VII. International Union of Pharmacology classification of receptors for 5-hydroxytryptamine (serotonin). Pharmacol Rev 46 2 (1994) 157-203
28. Islam A., Thompson K.S., Akhtar S., and Handley S.L. Increased 5-HT2A receptor expression and function following central glucocorticoid receptor knockdown in vivo. Eur J Pharmacol 502 3 (2004) 213-220
29. Izumi T., Suzuki K., Inoue T., Li X.B., Maki Y., Muraki I., et al. Long-lasting change in 5-HT2A receptor-mediated behavior in rats after a single foot shock. Eur J Pharmacol 452 (2002) 199-204
30. Kaur P., and Ahlenius S. Non-serotonergic potentiation by (-)-pindolol of DOI-induced forward locomotion in rats: possible involvement of beta-adrenoceptors?. J Neural Transm 107 (2000) 903-917
31. Kennett G.A., Wood M.D., Bright F., Trail B., Riley G., Holland V., et al. SB 242084, a selective and brain penetrant 5-HT2C receptor antagonist. Neuropharmacology 36 4-5 (1997) 609-620
32. Knight A.R., Misra A., Quirk K., Benwell K., Revell D., Kennett G., et al. Pharmacological cauterization of the agonist radioligand binding site of 5-HT(2A), 5-HT(2B) and 5-HT(2C) receptors. Naunyn Schmiedbergs Arch Pharmacol 370 2 (2004) 114-123
33. Koskinen T., Haapalinna A., and Sirvio J. Alpha-adrenoceptor-mediated modulation of 5-HT2 receptor agonist induced impulsive responding in a 5-choice serial reaction time task. Pharmacol Toxicol 92 5 (2003) 214-225
34. Krebs-Thomson K., and Geyer M.A. The role of 5-HT(1A) receptors in the locomotor-suppressant effects of LSD: WAY-100635 studies of 8-OH-DPAT, DOI and LSD in rats. Behav Pharmacol 7 (1996) 551-559
35. Kursar J.D., Nelson D.L., Wainscott D.B., and Baez M. Molecular cloning, functional expression, and mRNA tissue distribution of the human 5-hydroxytryptamine2B receptor. Mol Pharmacol 46 2 (1994) 227-234
36. 2 receptor antagonists on ethanol- and cocaine-induced locomotion. Pharmacol Biochem Behav 57 1-2 (1997) 325-332
37. 2 ligands and benzodiazepines co-administration: comparison of two animal models of anxiety (the four-plate test and the elevated plus maze). Behav Brain Res 177 (2007) 214-226
38. Millan M.J. The neurobiology and control of anxious states. Prog Neurobiol 70 (2003) 83-244
39. Millan M.J., Canton H., Gobert A., Lejeune F., Rivet J.M., Bervoets K., et al. Novel benzodiazepines acting as antagonists at 5-HT1A autoreceptors: a comparative pharmacological characterization with proposed 5-HT1A antagonists. J Pharmacol Exp Ther 268 1 (1994) 337-352
40. Mitchell P.J., Fairhall S.J., Fretcher A., and Redfern P.H. Effects of single and repeated electroconvulsive shock on the social and agonistic behaviour of resident rats. Neuropharmacology 44 7 (2003) 911-925
41. Miyata S., Hirano S., and Kamei J. Diabetes inhibits the DOI-induced head twitch response in mice. Psychopharmacology 177 (2004) 224-229
42. Mora P.O., Netto C.F., and Graeff F.G. Role of 5-HT2A and 5-HT2C receptor subtypes in the two types of fear generated by the elevated T-maze. Pharmacol Biochem Behav 58 4 (1997) 1051-1057
43. Nakamura K., and Kurasawa M. Anxiolytic effects of aniracetam in three different mouse models of anxiety and the underlying mechanism. Eur J Pharmacol 420 (2001) 33-43
44. Nic Dhonnchadha B.A., Bourin M., and Hascoet M. Anxiolytic-like effects of 5-HT2 ligands on three mouse models of anxiety. Behav Brain Res 140 (2003) 203-214
45. Nic Dhonnchadha B.A., Hascoet M., Jolliet P., and Bourin M. Evidence for a 5-HT2A receptor mode of action in the anxiolytic-like properties of DOI in mice. Behav Brain Res 147 (2003) 175-184
46. Njunge K., and Handley S.L. Effects of 5-HT uptake inhibitors, agonists and antagonists on the burying of harmless objects by mice; a putative test of anxiolytic agents. Br J Pharmacol 104 1 (1991) 105-112
47. Onaivi E.S., Bishop-Robinson C., Darmani N.A., and Sanders-Bush E. Behavioral effects of (+/-)-1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane, (DOI) in the elevated plus-maze test. Life Sci 57 26 (1995) 2455-2466
48. Peng W.H., Wu C.R., Chen C.S., Chen C.F., Leu Z.C., and Hsieh M.T. Anxiolytic effect of berberine on exploratory activity of the mouse in two experimental anxiety models: interaction with drugs acting at 5-HT receptors. Life Sci 75 (2004) 2451-2462
49. Pericic D. Swim stress inhibits 5-HT2A receptor-mediated head twitch behaviour in mice. Psychopharmacology (Berl) 167 (2003) 373-379
50. Petit-Demouliere B., Hascoet M., and Bourin M. Factors triggering abolishment of benzodiazepines effects in the four-plate test-retest in mice. Eur Neuropsychopharm 18 (2008) 41-47
51. Rademacher D.J., Anderson A.P., and Steinpreis R.E. Acute effects of amperozide and paroxetine on social cohesion in male conspecifics. Brain Res Bull 58 2 (2002) 187-191
52. Raghavendra V., and Kulkarni S.K. Melatonin reversal of DOI-induced hypophagia in rats; possible mechanism by suppressing 5-HT(2A) receptor-mediated activation of HPA axis. Brain Res 860 (2000) 112-118
53. Redrobe J.P., and Bourin M. Effects of pretreatment with clonidine, lithium and quinine on the activities of antidepressant drugs in the mouse tail suspension test. Fundam Clin Pharmacol 11 (1997) 381-386
54. 2A subtype receptors in DOI activity in the four-plates test-retest paradigm in mice. Behav Brain Res 166 (2006) 131-139
55. Rogers D.C., Costall B., Domeney A.M., Gerrard P.A., Greener M., Kelly M.E., Hagan J.J., and Hunter A.J. Anxiolytic profile of ropinirole in the rat, mouse and common marmoset. Psychopharmacology (Berl) 151 1 (2000) 91-97
56. Roth B.L., Tandra S., Burgess L.H., Sibley D.R., and Meltzer H.Y. D4 dopamine receptor binding affinity does not distinguish between typical and atypical antipsychotic drugs. Psychopharmacology (Berl) 120 3 (1995) 365-368
57. Samarghandian S., Ohata H., Yamauchi N., and Shibasaki T. Corticotropin-releasing factor as well as opioid and dopamine are involved in tail-pinch-induced food intake of rats. Neuroscience 116 2 (2003) 519-524
58. Sanchez C. Effect of serotonergic drugs on footshock-induced ultrasonic vocalization in adult male rats. Behav Pharmacol 4 (1993) 269-277
59. 1B-adrenoceptors for ketanserin between intact tissue segments and membrane preparations. Eur J Pharmacol 584 (2008) 222-228
60. Schreiber R., Melon C., and De Vry J. The role of 5-HT receptor subtypes in the anxiolytic effects of selective serotonin reuptake inhibitors in the rat ultrasonic vocalization test. Psychopharmacology 135 4 (1998) 383-391
61. Schwinn D.A., Johnston G.I., Page S.O., Mosley M.J., Wilson K.H., Worman N.P., et al. Cloning and pharmacological characterization of human alpha-1-adrenergic receptors: sequence corrections and direct comparison with other species homologues. J Pharmacol Exp Ther 272 1 (1995) 134-142
62. Sokal D.H., Giarola A.S., and Large C.H. Effects of GABA(B), 5-HT(1A), and 5-HT(2) receptor stimulation on activation and inhibition of the rat lateral amygdala following medial geniculate nucleus stimulation in vivo. Brain Res 1031 1 (2005) 141-150
63. Swerdlow N.R., Keith V.A., Braff D.L., and Geyer M.A. Effects of spiperone, raclopride, SCH 23390 and clozapine on apomorphine inhibition of sensorimotor gating of the startle response in the rat. J Pharacol Exp Ther 256 2 (1991) 530-536
64. Tadano T., Hozumi M., Satoh N., Oka R., Hishinuma T., Mizugaki M., et al. Central serotonergic mechanisms on head twitch response induced by benzodiazepine receptor agonists. Pharmacology 62 (2001) 157-162
65. Takao K., Nagatani T., Kitamura Y., Kawasaki K., Hayakawa H., and Yamawaki S. Chronic forced swim stress of rats increases frontal cortical 5-HT2 receptors and the wet-dog shakes they mediate, but not frontal cortical beta-adrenoceptors. Eur J Pharmacol 294 (1995) 721-726
66. Tang L., Todd R.D., Heller A., and O'Malley K.L. Pharmacological and functional chacterization of D2, D3 and D4 dopamine receptors in fibroblast and dopaminergic cell lines. J Pharmacol Exp Ther 268 1 (1994) 495-502
67. To C.T., and Bagdy G. Anxiogenic effect of central CCK administration is attenuated by chronic fluoxetine or ipsapirone treatment. Neuropharmacology 38 2 (1999) 279-282
68. Toll L., Berzetei-Gurske I.P., Polgar W.E., Brandt S.R., Adapa I.D., Rodriguez L., et al. Standard binding and functional assays related to medications development division testing for potential cocaine and opiate narcotic treatment medications. NIDA Res Monogr 178 (1998) 440-466
69. Wax J., McLean J.R., Tessman D.K., McCarthy D.A., and Nuite J.A. Duration of antinociceptive action of morphine, methadone and α-l-acetylmethadol subcutaneously in rats. Res Com Chem Path Pharmacol 12 4 (1975) 613-620
70. Winslow J.T., and Insel T.R. Serotonergic modulation of the rat pup ultrasonic isolation call: Studies with 5HT1 and 5HT2 subtype-selective agonists and antagonists. Psychopharmacology (Berl) 105 (1991) 513-520
71. Yamada S., Nankai M., and Toru M. Acute immobilization stress reduces (+/-) DOI induced 5-HT2-mediated head shakes in rats. Jpn J Psychiatry Neurol 47 (1993) 414-415
72. Yamada S., Watanabe A., Nankai M., and Toru M. Acute immobilization stress reduces (+/-) DOI-induced 5-HT2A receptor-mediated head shakes in rats. Psychopharmacology (Berl) 119 (1995) 9-14