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Volumn 5, Issue , 2008, Pages

Dominant negative mutant cyclin T1 proteins inhibit HIV transcription by specifically degrading Tat

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN D1; CYCLIN T1; MUTANT PROTEIN; POSITIVE TRANSCRIPTION ELONGATION FACTOR B; PROTEASOME INHIBITOR; TRANSACTIVATOR PROTEIN; CCNT1 PROTEIN, HUMAN; CYCLINE;

EID: 48649095343     PISSN: None     EISSN: 17424690     Source Type: Journal    
DOI: 10.1186/1742-4690-5-63     Document Type: Article
Times cited : (19)

References (46)
  • 1
    • 0032701796 scopus 로고    scopus 로고
    • Tackling Tat
    • 10.1006/jmbi.1999.3060 10550206
    • Karn J Tackling Tat J Mol Biol 1999, 293:235-254. 10.1006/jmbi.1999.3060 10550206
    • (1999) J Mol Biol , vol.293 , pp. 235-254
    • Karn, J.1
  • 2
    • 0033604520 scopus 로고    scopus 로고
    • Tat transactivation: A model for the regulation of eukaryotic transcriptional elongation
    • 10.1006/viro.1999.9944 10562489
    • Taube R Fujinaga K Wimmer J Barboric M Peterlin BM Tat transactivation: a model for the regulation of eukaryotic transcriptional elongation Virology 1999, 264:245-253. 10.1006/viro.1999.9944 10562489
    • (1999) Virology , vol.264 , pp. 245-253
    • Taube, R.1    Fujinaga, K.2    Wimmer, J.3    Barboric, M.4    Peterlin, B.M.5
  • 3
    • 0032401752 scopus 로고    scopus 로고
    • Recruitment of a protein complex containing Tat and cyclin T1 to TAR governs the species specificity of HIV-1 Tat
    • 1171053 9843510 10.1093/emboj/17.23.7056
    • Bieniasz PD Grdina TA Bogerd HP Cullen BR Recruitment of a protein complex containing Tat and cyclin T1 to TAR governs the species specificity of HIV-1 Tat Embo J 1998, 17:7056-7065. 1171053 9843510 10.1093/emboj/17.23.7056
    • (1998) Embo J , vol.17 , pp. 7056-7065
    • Bieniasz, P.D.1    Grdina, T.A.2    Bogerd, H.P.3    Cullen, B.R.4
  • 4
    • 0033574077 scopus 로고    scopus 로고
    • Interactions between human cyclin T, Tat, and the transactivation response element (TAR) are disrupted by a cysteine to tyrosine substitution found in mouse cyclin T
    • 15455 9990016 10.1073/pnas.96.4.1285
    • Fujinaga K Taube R Wimmer J Cujec TP Peterlin BM Interactions between human cyclin T, Tat, and the transactivation response element (TAR) are disrupted by a cysteine to tyrosine substitution found in mouse cyclin T Proc Natl Acad Sci USA 1999, 96:1285-1290. 15455 9990016 10.1073/ pnas.96.4.1285
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 1285-1290
    • Fujinaga, K.1    Taube, R.2    Wimmer, J.3    Cujec, T.P.4    Peterlin, B.M.5
  • 5
    • 0032533253 scopus 로고    scopus 로고
    • The interaction between HIV-1 Tat and human cyclin T1 requires zinc and a critical cysteine residue that is not conserved in the murine CycT1 protein
    • 317238 9832504 10.1101/gad.12.22.3512
    • Garber ME Wei P KewalRamani VN Mayall TP Herrmann CH Rice AP Littman DR Jones KA The interaction between HIV-1 Tat and human cyclin T1 requires zinc and a critical cysteine residue that is not conserved in the murine CycT1 protein Genes Dev 1998, 12:3512-3527. 317238 9832504 10.1101/ gad.12.22.3512
    • (1998) Genes Dev , vol.12 , pp. 3512-3527
    • Garber, M.E.1    Wei, P.2    KewalRamani, V.N.3    Mayall, T.P.4    Herrmann, C.H.5    Rice, A.P.6    Littman, D.R.7    Jones, K.A.8
  • 6
    • 0036275982 scopus 로고    scopus 로고
    • Phosphorylation of the RNA polymerase II carboxyl-terminal domain by CDK9 is directly responsible for human immunodeficiency virus type 1 Tat-activated transcriptional elongation
    • 133925 12052871 10.1128/MCB.22.13.4622-4637.2002
    • Kim YK Bourgeois CF Isel C Churcher MJ Karn J Phosphorylation of the RNA polymerase II carboxyl-terminal domain by CDK9 is directly responsible for human immunodeficiency virus type 1 Tat-activated transcriptional elongation Mol Cell Biol 2002, 22:4622-4637. 133925 12052871 10.1128/ MCB.22.13.4622-4637.2002
    • (2002) Mol Cell Biol , vol.22 , pp. 4622-4637
    • Kim, Y.K.1    Bourgeois, C.F.2    Isel, C.3    Churcher, M.J.4    Karn, J.5
  • 7
    • 0032031706 scopus 로고    scopus 로고
    • Identification of multiple cyclin subunits of human P-TEFb
    • 316581 9499409 10.1101/gad.12.5.755
    • Peng J Zhu Y Milton JT Price DH Identification of multiple cyclin subunits of human P-TEFb Genes Dev 1998, 12:755-762. 316581 9499409 10.1101/gad.12.5.755
    • (1998) Genes Dev , vol.12 , pp. 755-762
    • Peng, J.1    Zhu, Y.2    Milton, J.T.3    Price, D.H.4
  • 8
    • 0033597346 scopus 로고    scopus 로고
    • Role of the human and murine cyclin T proteins in regulating HIV-1 tat-activation
    • 10.1006/jmbi.1999.2664 10329126
    • Kwak YT Ivanov D Guo J Nee E Gaynor RB Role of the human and murine cyclin T proteins in regulating HIV-1 tat-activation J Mol Biol 1999, 288:57-69. 10.1006/jmbi.1999.2664 10329126
    • (1999) J Mol Biol , vol.288 , pp. 57-69
    • Kwak, Y.T.1    Ivanov, D.2    Guo, J.3    Nee, E.4    Gaynor, R.B.5
  • 9
    • 0033597175 scopus 로고    scopus 로고
    • Cyclin T1 domains involved in complex formation with Tat and TAR RNA are critical for tat-activation
    • 10.1006/jmbi.1999.2663 10329125
    • Ivanov D Kwak YT Nee E Guo J Garcia-Martinez LF Gaynor RB Cyclin T1 domains involved in complex formation with Tat and TAR RNA are critical for tat-activation J Mol Biol 1999, 288:41-56. 10.1006/jmbi.1999.2663 10329125
    • (1999) J Mol Biol , vol.288 , pp. 41-56
    • Ivanov, D.1    Kwak, Y.T.2    Nee, E.3    Guo, J.4    Garcia-Martinez, L.F.5    Gaynor, R.B.6
  • 10
    • 0034602250 scopus 로고    scopus 로고
    • HIV-1 TAR RNA enhances the interaction between Tat and cyclin T1
    • 10.1074/jbc.M006804200 10944537
    • Zhang J Tamilarasu N Hwang S Garber ME Huq I Jones KA Rana TM HIV-1 TAR RNA enhances the interaction between Tat and cyclin T1 J Biol Chem 2000, 275:34314-34319. 10.1074/jbc.M006804200 10944537
    • (2000) J Biol Chem , vol.275 , pp. 34314-34319
    • Zhang, J.1    Tamilarasu, N.2    Hwang, S.3    Garber, M.E.4    Huq, I.5    Jones, K.A.6    Rana, T.M.7
  • 11
    • 33749234198 scopus 로고    scopus 로고
    • The Yin and Yang of P-TEFb regulation: Implications for human immunodeficiency virus gene expression and global control of cell growth and differentiation
    • 1594588 16959964 10.1128/MMBR.00011-06
    • Zhou Q Yik JH The Yin and Yang of P-TEFb regulation: Implications for human immunodeficiency virus gene expression and global control of cell growth and differentiation Microbiol Mol Biol Rev 2006, 70:646-659. 1594588 16959964 10.1128/MMBR.00011-06
    • (2006) Microbiol Mol Biol Rev , vol.70 , pp. 646-659
    • Zhou, Q.1    Yik, J.H.2
  • 13
    • 0038111978 scopus 로고    scopus 로고
    • MAQ1 and 7SK RNA interact with CDK9/cyclin T complexes in a transcription-dependent manner
    • 162212 12832472 10.1128/MCB.23.14.4859-4869.2003
    • Michels AA Nguyen VT Fraldi A Labas V Edwards M Bonnet F Lania L Bensaude O MAQ1 and 7SK RNA interact with CDK9/cyclin T complexes in a transcription-dependent manner Mol Cell Biol 2003, 23:4859-4869. 162212 12832472 10.1128/MCB.23.14.4859-4869.2003
    • (2003) Mol Cell Biol , vol.23 , pp. 4859-4869
    • Michels, A.A.1    Nguyen, V.T.2    Fraldi, A.3    Labas, V.4    Edwards, M.5    Bonnet, F.6    Lania, L.7    Bensaude, O.8
  • 15
    • 21644468867 scopus 로고    scopus 로고
    • Identification of a cyclin T-binding domain in Hexim1 and biochemical analysis of its binding competition with HIV-1 Tat
    • 10.1074/jbc.M501431200 15855166
    • Schulte A Czudnochowski N Barboric M Schonichen A Blazek D Peterlin BM Geyer M Identification of a cyclin T-binding domain in Hexim1 and biochemical analysis of its binding competition with HIV-1 Tat J Biol Chem 2005, 280:24968-24977. 10.1074/jbc.M501431200 15855166
    • (2005) J Biol Chem , vol.280 , pp. 24968-24977
    • Schulte, A.1    Czudnochowski, N.2    Barboric, M.3    Schonichen, A.4    Blazek, D.5    Peterlin, B.M.6    Geyer, M.7
  • 16
    • 0033529211 scopus 로고    scopus 로고
    • Recruitment of cyclin T1/P-TEFb to an HIV type 1 long terminal repeat promoter proximal RNA target is both necessary and sufficient for full activation of transcription
    • 22140 10393900 10.1073/pnas.96.14.7791
    • Bieniasz PD Grdina TA Bogerd HP Cullen BR Recruitment of cyclin T1/ P-TEFb to an HIV type 1 long terminal repeat promoter proximal RNA target is both necessary and sufficient for full activation of transcription Proc Natl Acad Sci USA 1999, 96:7791-7796. 22140 10393900 10.1073/pnas.96.14.7791
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 7791-7796
    • Bieniasz, P.D.1    Grdina, T.A.2    Bogerd, H.P.3    Cullen, B.R.4
  • 17
    • 0032450548 scopus 로고    scopus 로고
    • HIV-1 Tat interacts with cyclin T1 to direct the P-TEFb CTD kinase complex to TAR RNA
    • 10.1101/sqb.1998.63.371 10384302
    • Garber ME Wei P Jones KA HIV-1 Tat interacts with cyclin T1 to direct the P-TEFb CTD kinase complex to TAR RNA Cold Spring Harb Symp Quant Biol 1998, 63:371-380. 10.1101/sqb.1998.63.371 10384302
    • (1998) Cold Spring Harb Symp Quant Biol , vol.63 , pp. 371-380
    • Garber, M.E.1    Wei, P.2    Jones, K.A.3
  • 18
    • 34250196457 scopus 로고    scopus 로고
    • Cyclin box structure of the P-TEFb subunit cyclin T1 derived from a fusion complex with EIAV tat
    • 10.1016/j.jmb.2007.04.077 17540406
    • Anand K Schulte A Fujinaga K Scheffzek K Geyer M Cyclin box structure of the P-TEFb subunit cyclin T1 derived from a fusion complex with EIAV tat J Mol Biol 2007, 370:826-836. 10.1016/j.jmb.2007.04.077 17540406
    • (2007) J Mol Biol , vol.370 , pp. 826-836
    • Anand, K.1    Schulte, A.2    Fujinaga, K.3    Scheffzek, K.4    Geyer, M.5
  • 19
    • 35448950935 scopus 로고    scopus 로고
    • Structure of the Cyclin T binding domain of Hexim1 and molecular basis for its recognition of P-TEFb
    • 1955226 17724342 10.1073/pnas.0701848104
    • Dames SA Schonichen A Schulte A Barboric M Peterlin BM Grzesiek S Geyer M Structure of the Cyclin T binding domain of Hexim1 and molecular basis for its recognition of P-TEFb Proc Natl Acad Sci USA 2007, 104:14312-14317. 1955226 17724342 10.1073/pnas.0701848104
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 14312-14317
    • Dames, S.A.1    Schonichen, A.2    Schulte, A.3    Barboric, M.4    Peterlin, B.M.5    Grzesiek, S.6    Geyer, M.7
  • 21
  • 22
    • 0036008846 scopus 로고    scopus 로고
    • Structure-based computational database screening, in vitro assay, and NMR assessment of compounds that target TAR RNA
    • 10.1016/S1074-5521(02)00106-0 11880033
    • Lind KE Du Z Fujinaga K Peterlin BM James TL Structure-based computational database screening, in vitro assay, and NMR assessment of compounds that target TAR RNA Chem Biol 2002, 9:185-193. 10.1016/ S1074-5521(02)00106-0 11880033
    • (2002) Chem Biol , vol.9 , pp. 185-193
    • Lind, K.E.1    Du, Z.2    Fujinaga, K.3    Peterlin, B.M.4    James, T.L.5
  • 24
    • 33646534201 scopus 로고    scopus 로고
    • Inhibitors of HIV-1 Tat-mediated transactivation
    • 10.2174/092986706776872989 16712471
    • Richter SN Palu G Inhibitors of HIV-1 Tat-mediated transactivation Curr Med Chem 2006, 13:1305-1315. 10.2174/092986706776872989 16712471
    • (2006) Curr Med Chem , vol.13 , pp. 1305-1315
    • Richter, S.N.1    Palu, G.2
  • 25
    • 27944474355 scopus 로고    scopus 로고
    • Indirubin-3′-monoxime, a derivative of a Chinese antileukemia medicine, inhibits P-TEFb function and HIV-1 replication
    • 16284457
    • Heredia A Davis C Bamba D Le N Gwarzo MY Sadowska M Gallo RC Redfield RR Indirubin-3′-monoxime, a derivative of a Chinese antileukemia medicine, inhibits P-TEFb function and HIV-1 replication Aids 2005, 19:2087-2095. 16284457
    • (2005) Aids , vol.19 , pp. 2087-2095
    • Heredia, A.1    Davis, C.2    Bamba, D.3    Le, N.4    Gwarzo, M.Y.5    Sadowska, M.6    Gallo, R.C.7    Redfield, R.R.8
  • 26
    • 0141866666 scopus 로고    scopus 로고
    • Discovery of a small molecule Tat-trans-activation-responsive RNA antagonist that potently inhibits human immunodeficiency virus-1 replication
    • 10.1074/jbc.M301749200 12857725
    • Hwang S Tamilarasu N Kibler K Cao H Ali A Ping YH Jeang KT Rana TM Discovery of a small molecule Tat-trans-activation-responsive RNA antagonist that potently inhibits human immunodeficiency virus-1 replication J Biol Chem 2003, 278:39092-39103. 10.1074/jbc.M301749200 12857725
    • (2003) J Biol Chem , vol.278 , pp. 39092-39103
    • Hwang, S.1    Tamilarasu, N.2    Kibler, K.3    Cao, H.4    Ali, A.5    Ping, Y.H.6    Jeang, K.T.7    Rana, T.M.8
  • 27
    • 0034608946 scopus 로고    scopus 로고
    • Inhibition of the RNA-dependent transactivation and replication of human immunodeficiency virus type 1 by a fluoroquinoline derivative K-37
    • 10.1006/viro.2000.0396 10873784
    • Okamoto H Cujec TP Okamoto M Peterlin BM Baba M Okamoto T Inhibition of the RNA-dependent transactivation and replication of human immunodeficiency virus type 1 by a fluoroquinoline derivative K-37 Virology 2000, 272:402-408. 10.1006/viro.2000.0396 10873784
    • (2000) Virology , vol.272 , pp. 402-408
    • Okamoto, H.1    Cujec, T.P.2    Okamoto, M.3    Peterlin, B.M.4    Baba, M.5    Okamoto, T.6
  • 28
    • 0037458719 scopus 로고    scopus 로고
    • Tat and trans-activation-responsive (TAR) RNA-independent induction of HIV-1 long terminal repeat by human and murine cyclin T1 requires Sp1
    • 10.1074/jbc.M209162200 12458222
    • Yedavalli VS Benkirane M Jeang KT Tat and trans-activation-responsive (TAR) RNA-independent induction of HIV-1 long terminal repeat by human and murine cyclin T1 requires Sp1 J Biol Chem 2003, 278:6404-6410. 10.1074/jbc.M209162200 12458222
    • (2003) J Biol Chem , vol.278 , pp. 6404-6410
    • Yedavalli, V.S.1    Benkirane, M.2    Jeang, K.T.3
  • 29
    • 0043067987 scopus 로고    scopus 로고
    • Functional inactivation of Cdk9 through oligomerization chain reaction
    • 10.1038/sj.onc.1206785 12894230
    • Napolitano G Mazzocco A Fraldi A Majello B Lania L Functional inactivation of Cdk9 through oligomerization chain reaction Oncogene 2003, 22:4882-4888. 10.1038/sj.onc.1206785 12894230
    • (2003) Oncogene , vol.22 , pp. 4882-4888
    • Napolitano, G.1    Mazzocco, A.2    Fraldi, A.3    Majello, B.4    Lania, L.5
  • 30
    • 0036838641 scopus 로고    scopus 로고
    • Optimized chimeras between kinase-inactive mutant Cdk9 and truncated cyclin T1 proteins efficiently inhibit Tat transactivation and human immunodeficiency virus gene expression
    • 136629 12368330 10.1128/JVI.76.21.10873-10881.2002
    • Fujinaga K Irwin D Geyer M Peterlin BM Optimized chimeras between kinase-inactive mutant Cdk9 and truncated cyclin T1 proteins efficiently inhibit Tat transactivation and human immunodeficiency virus gene expression J Virol 2002, 76:10873-10881. 136629 12368330 10.1128/ JVI.76.21.10873-10881.2002
    • (2002) J Virol , vol.76 , pp. 10873-10881
    • Fujinaga, K.1    Irwin, D.2    Geyer, M.3    Peterlin, B.M.4
  • 31
    • 17144430455 scopus 로고    scopus 로고
    • Granulin and granulin repeats interact with the Tat.P-TEFb complex and inhibit Tat transactivation
    • 10.1074/jbc.M409575200 15653695
    • Hoque M Tian B Mathews MB Pe'ery T Granulin and granulin repeats interact with the Tat.P-TEFb complex and inhibit Tat transactivation J Biol Chem 2005, 280:13648-13657. 10.1074/jbc.M409575200 15653695
    • (2005) J Biol Chem , vol.280 , pp. 13648-13657
    • Hoque, M.1    Tian, B.2    Mathews, M.B.3    Pe'ery, T.4
  • 32
    • 0037371643 scopus 로고    scopus 로고
    • The growth factor granulin interacts with cyclin T1 and modulates P-TEFb-dependent transcription
    • 151712 12588988 10.1128/MCB.23.5.1688-1702.2003
    • Hoque M Young TM Lee CG Serrero G Mathews MB Pe'ery T The growth factor granulin interacts with cyclin T1 and modulates P-TEFb-dependent transcription Mol Cell Biol 2003, 23:1688-1702. 151712 12588988 10.1128/ MCB.23.5.1688-1702.2003
    • (2003) Mol Cell Biol , vol.23 , pp. 1688-1702
    • Hoque, M.1    Young, T.M.2    Lee, C.G.3    Serrero, G.4    Mathews, M.B.5    Pe'ery, T.6
  • 33
    • 0042692788 scopus 로고    scopus 로고
    • The human I-mfa domain-containing protein, HIC, interacts with cyclin T1 and modulates P-TEFb-dependent transcription
    • 193714 12944466 10.1128/MCB.23.18.6373-6384.2003
    • Young TM Wang Q Pe'ery T Mathews MB The human I-mfa domain-containing protein, HIC, interacts with cyclin T1 and modulates P-TEFb-dependent transcription Mol Cell Biol 2003, 23:6373-6384. 193714 12944466 10.1128/ MCB.23.18.6373-6384.2003
    • (2003) Mol Cell Biol , vol.23 , pp. 6373-6384
    • Young, T.M.1    Wang, Q.2    Pe'ery, T.3    Mathews, M.B.4
  • 34
    • 0037449785 scopus 로고    scopus 로고
    • Inhibition of Tat-mediated transactivation and HIV-1 replication by human anti-hCyclinT1 intrabodies
    • 10.1074/jbc.M208297200 12401780
    • Bai J Sui J Zhu RY Tallarico AS Gennari F Zhang D Marasco WA Inhibition of Tat-mediated transactivation and HIV-1 replication by human anti-hCyclinT1 intrabodies J Biol Chem 2003, 278:1433-1442. 10.1074/ jbc.M208297200 12401780
    • (2003) J Biol Chem , vol.278 , pp. 1433-1442
    • Bai, J.1    Sui, J.2    Zhu, R.Y.3    Tallarico, A.S.4    Gennari, F.5    Zhang, D.6    Marasco, W.A.7
  • 35
    • 0035943710 scopus 로고    scopus 로고
    • Flavopiridol inactivates P-TEFb and blocks most RNA polymerase II transcription in vivo
    • 10.1074/jbc.M102306200 11431468
    • Chao SH Price DH Flavopiridol inactivates P-TEFb and blocks most RNA polymerase II transcription in vivo J Biol Chem 2001, 276:31793-31799. 10.1074/jbc.M102306200 11431468
    • (2001) J Biol Chem , vol.276 , pp. 31793-31799
    • Chao, S.H.1    Price, D.H.2
  • 36
    • 0032548918 scopus 로고    scopus 로고
    • A novel CDK9-associated C-type cyclin interacts directly with HIV-1 Tat and mediates its high-affinity, loop-specific binding to TAR RNA
    • 10.1016/S0092-8674(00)80939-3 9491887
    • Wei P Garber ME Fang SM Fischer WH Jones KA A novel CDK9-associated C-type cyclin interacts directly with HIV-1 Tat and mediates its high-affinity, loop-specific binding to TAR RNA Cell 1998, 92:451-462. 10.1016/S0092-8674(00)80939-3 9491887
    • (1998) Cell , vol.92 , pp. 451-462
    • Wei, P.1    Garber, M.E.2    Fang, S.M.3    Fischer, W.H.4    Jones, K.A.5
  • 37
    • 2942715351 scopus 로고    scopus 로고
    • VP16 and ubiquitin; binding of P-TEFb via its activation domain and ubiquitin facilitates elongation of transcription of target genes
    • 10.1016/j.cub.2004.06.020 15203006
    • Kurosu T Peterlin BM VP16 and ubiquitin; binding of P-TEFb via its activation domain and ubiquitin facilitates elongation of transcription of target genes Curr Biol 2004, 14:1112-1116. 10.1016/j.cub.2004.06.020 15203006
    • (2004) Curr Biol , vol.14 , pp. 1112-1116
    • Kurosu, T.1    Peterlin, B.M.2
  • 38
    • 0036891860 scopus 로고    scopus 로고
    • A minimal chimera of human cyclin T1 and tat binds TAR and activates human immunodeficiency virus transcription in murine cells
    • 136680 12438619 10.1128/JVI.76.24.12934-12939.2002
    • Fujinaga K Irwin D Taube R Zhang F Geyer M Peterlin BM A minimal chimera of human cyclin T1 and tat binds TAR and activates human immunodeficiency virus transcription in murine cells J Virol 2002, 76:12934-12939. 136680 12438619 10.1128/JVI.76.24.12934-12939.2002
    • (2002) J Virol , vol.76 , pp. 12934-12939
    • Fujinaga, K.1    Irwin, D.2    Taube, R.3    Zhang, F.4    Geyer, M.5    Peterlin, B.M.6
  • 39
    • 0033986157 scopus 로고    scopus 로고
    • Interactions between equine cyclin T1, Tat, and TAR are disrupted by a leucine-to-valine substitution found in human cyclin T1
    • 111610 10623752 10.1128/JVI.74.2.892-898.2000
    • Taube R Fujinaga K Irwin D Wimmer J Geyer M Peterlin BM Interactions between equine cyclin T1, Tat, and TAR are disrupted by a leucine-to-valine substitution found in human cyclin T1 J Virol 2000, 74:892-898. 111610 10623752 10.1128/JVI.74.2.892-898.2000
    • (2000) J Virol , vol.74 , pp. 892-898
    • Taube, R.1    Fujinaga, K.2    Irwin, D.3    Wimmer, J.4    Geyer, M.5    Peterlin, B.M.6
  • 40
    • 3242769187 scopus 로고    scopus 로고
    • Cellular control of gene expression by T-type cyclin/CDK9 complexes
    • 10.1016/j.gene.2004.05.007 15276198
    • Garriga J Grana X Cellular control of gene expression by T-type cyclin/ CDK9 complexes Gene 2004, 337:15-23. 10.1016/j.gene.2004.05.007 15276198
    • (2004) Gene , vol.337 , pp. 15-23
    • Garriga, J.1    Grana, X.2
  • 41
    • 33746403681 scopus 로고    scopus 로고
    • Controlling the elongation phase of transcription with P-TEFb
    • 10.1016/j.molcel.2006.06.014 16885020
    • Peterlin BM Price DH Controlling the elongation phase of transcription with P-TEFb Mol Cell 2006, 23:297-305. 10.1016/j.molcel.2006.06.014 16885020
    • (2006) Mol Cell , vol.23 , pp. 297-305
    • Peterlin, B.M.1    Price, D.H.2
  • 42
    • 33747605357 scopus 로고    scopus 로고
    • Recruitment of TFIIH to the HIV LTR is a rate-limiting step in the emergence of HIV from latency
    • 1538560 16874302 10.1038/sj.emboj.7601248
    • Kim YK Bourgeois CF Pearson R Tyagi M West MJ Wong J Wu SY Chiang CM Karn J Recruitment of TFIIH to the HIV LTR is a rate-limiting step in the emergence of HIV from latency Embo J 2006, 25:3596-3604. 1538560 16874302 10.1038/sj.emboj.7601248
    • (2006) Embo J , vol.25 , pp. 3596-3604
    • Kim, Y.K.1    Bourgeois, C.F.2    Pearson, R.3    Tyagi, M.4    West, M.J.5    Wong, J.6    Wu, S.Y.7    Chiang, C.M.8    Karn, J.9
  • 43
    • 0346095303 scopus 로고    scopus 로고
    • Dynamics of Human Immunodeficiency Virus Transcription: P-TEFb Phosphorylates RD and Dissociates Negative Effectors from the Transactivation Response Element
    • 343783 14701750 10.1128/MCB.24.2.787-795.2004
    • Fujinaga K Irwin D Huang Y Taube R Kurosu T Peterlin BM Dynamics of Human Immunodeficiency Virus Transcription: P-TEFb Phosphorylates RD and Dissociates Negative Effectors from the Transactivation Response Element Mol Cell Biol 2004, 24:787-795. 343783 14701750 10.1128/ MCB.24.2.787-795.2004
    • (2004) Mol Cell Biol , vol.24 , pp. 787-795
    • Fujinaga, K.1    Irwin, D.2    Huang, Y.3    Taube, R.4    Kurosu, T.5    Peterlin, B.M.6
  • 44
    • 0031710033 scopus 로고    scopus 로고
    • A third-generation lentivirus vector with a conditional packaging system
    • 110254 9765382
    • Dull T Zufferey R Kelly M Mandel RJ Nguyen M Trono D Naldini L A third-generation lentivirus vector with a conditional packaging system J Virol 1998, 72:8463-8471. 110254 9765382
    • (1998) J Virol , vol.72 , pp. 8463-8471
    • Dull, T.1    Zufferey, R.2    Kelly, M.3    Mandel, R.J.4    Nguyen, M.5    Trono, D.6    Naldini, L.7
  • 45
    • 37149031062 scopus 로고    scopus 로고
    • CBF-1 promotes transcriptional silencing during the establishment of HIV-1 latency
    • 10.1038/sj.emboj.7601928 18007589
    • Tyagi M Karn J CBF-1 promotes transcriptional silencing during the establishment of HIV-1 latency EMBO J 2007, 26:4985-4995. 10.1038/ sj.emboj.7601928 18007589
    • (2007) EMBO J , vol.26 , pp. 4985-4995
    • Tyagi, M.1    Karn, J.2
  • 46
    • 0029996147 scopus 로고    scopus 로고
    • In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector
    • 10.1126/science.272.5259.263 8602510
    • Naldini L Blomer U Gallay P Ory D Mulligan R Gage FH Verma IM Trono D In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector Science 1996, 272:263-267. 10.1126/ science.272.5259.263 8602510
    • (1996) Science , vol.272 , pp. 263-267
    • Naldini, L.1    Blomer, U.2    Gallay, P.3    Ory, D.4    Mulligan, R.5    Gage, F.H.6    Verma, I.M.7    Trono, D.8


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