Changing the Determinants of Protein Stability from Covalent to Non-Covalent Interactions by In Vitro Evolution: A Structural and Energetic Analysis

Journal of Molecular Biology

Volumn 381, Issue 4, 2008, Pages 1040-1054

  Kather, Insa ^a   Jakob, Roman ^a   Dobbek, Holger ^a   Schmid, Franz X ^a  

^a UNIVERSITY OF BAYREUTH   (Germany)

Author keywords

disulfide bonds; evolutionary protein design; phage display; phage gene 3 protein; protein stabilization

Indexed keywords

AMINO ACID; DISULFIDE; GENE 3 PROTEIN; VIRUS PROTEIN;

AMINO ACID SUBSTITUTION; ARTICLE; CHEMICAL BOND; CONFORMATIONAL TRANSITION; COVALENT BOND; CRYSTAL STRUCTURE; DISULFIDE BOND; ENERGY TRANSFER; GENE MUTATION; IN VITRO STUDY; MOLECULAR EVOLUTION; MOLECULAR INTERACTION; MOLECULAR STABILITY; MUTATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN CROSS LINKING; PROTEIN DOMAIN; PROTEIN FOLDING; PROTEIN INTERACTION; PROTEIN STABILITY; PROTEIN STRUCTURE; THERMOSTABILITY; WILD TYPE;

ENTEROBACTERIA PHAGE FD;

EID: 48449105553     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmb.2008.06.073     Document Type: Article

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