Screening for stable mutants with amino acid pairs substituted for the disulfide bond between residues 14 and 38 of bovine pancreatic trypsin inhibitor (BPTI)

Journal of Biological Chemistry

Volumn 277, Issue 52, 2002, Pages 51043-51048

  Hagihara, Yoshihisa ^a   Shiraki, Kentaro ^b   Nakamura, Tsutomu ^a   Uegaki, Koichi ^a   Takagi, Masahiro ^b   Imanaka, Tadayuki ^c   Yumoto, Noboru ^a  

^a NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY AIST   (Japan)

^b JAPAN ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY   (Japan)

^c KYOTO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; CHEMICAL BONDS; ENZYME INHIBITION; MUTAGENESIS; PROTEINS; THERMODYNAMICS;

DISULFIDE BONDS;

BIOCHEMISTRY;

AMINO ACID; APROTININ; CYSTEINE; DISULFIDE; RECOMBINANT PROTEIN; TRYPSIN;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANALYTIC METHOD; ARTICLE; CONTROLLED STUDY; DISULFIDE BOND; ENTHALPY; NONHUMAN; PRIORITY JOURNAL; PROTEIN FOLDING; PROTEIN RENATURATION; PROTEIN STABILITY; SCREENING;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMALS; APROTININ; CATTLE; CIRCULAR DICHROISM; CLONING, MOLECULAR; DISULFIDES; ENTROPY; GENE LIBRARY; MUTAGENESIS, SITE-DIRECTED; PROTEIN CONFORMATION; PROTEIN DENATURATION; THERMODYNAMICS;

BOVINAE;

EID: 0347297568     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M208893200     Document Type: Article

References (38)

1. Staley, J. P., and Kim, P. S. (1992) Proc. Natl. Acad. Sci. U. S. A. 89, 1519-1523
2. Zavodszky, M., Chen, C. W., Huang, J. K., Zolkiewski, M., Wen, L., and Krishnamoorthi, R. (2001) Protein Sci. 10, 149-160
3. Tachibana, H., Ohta, K, Sawano, H., Koumoto, Y., and Segawa, S. (1994) Biochemistry 33, 15008-15016
4. Mayr, L. M., Willbold, D., Landt, O., and Schmid, F. X. (1994) Protein Sci. 3, 227-239
5. Ohhashi, Y., Hagihara, Y., Kozhukh, G., Hoshino, M., Hasegawa, K., Yamaguchi, I., Naiki, H., and Goto, Y. (2002) J. Biochem. (Tokyo) 131, 45-52
6. Ramm, K, Gehrig, P., and Plückthun, A. (1999) J. Mol. Biol. 290, 535-546
7. Goto, Y., and Hamaguchi, K. (1979) J. Biochem. (Tokyo) 86, 1433-1441
8. Kieke, M. C, Shusta, E. V., Boder, E. T., Teyton, L., Wittrup, K. D., and Kranz, D. M. (1999) Proc. Natl. Acad. Sci. U. S. A. 96, 5651-5656
9. Shusta, E. V., Holler, P. D., Kieke, M. C, Kranz, D. M., and Wittrup, K. D., (2000) Nat. Biotechnol. 18, 754-759
10. Hagihara, Y., and Kim, P. S. (2002) Proc. Natl. Acad. Sci. U. S. A. 99, 6619-6624
11. Ellgaard, L., Molinari, M., and Helenius, A. (1999) Science 286, 1882-1888
12. Hendershot, L., Bole, D., Kohler, G., and Kearney, J. F. (1987) J. Cell Biol. 104, 761-767
13. Trombetta, E. S., and Helenius, A. (2000) J. Cell Biol. 148, 1123-1129
14. Blond-Elguindi, S., Cwirla, S. E., Dower, W. J., Lipshutz, R. J., Sprang, S. R., Sambrook, J. F., and Gething, M. J. (1993) Cell 75, 717-728
15. Kowalski, J. M., Parekh, R. N., Mao, J., and Wittrup, K. D. (1998) J. Biol. Chem. 273, 19453-19458
16. Kowalski, J. M., Parekh, R. N., and Wittrup, K. D. (1998) Biochemistry 37, 1264-1273
17. Kjeldsen, T., Ludvigsen, S., Diers, I., Balschmidt, P., Sørensen, A. R., and Kaarsholm, N. C. (2002) J. Biol. Chem. 277, 18245-18248
18. Hong, E., Davidson, A. R., and Kaiser, C. A. (1996) J. Cell Biol. 135, 623-633
19. Weissman, J. S., and Kim, P. S. (1995) Nat. Struct. Biol. 2, 1123-1130
20. Kuroda, Y., and Kim, P. S. (2000) J. Mol. Biol. 298, 493-501
21. Moses, E., and Hinz, H. J. (1983) J. Mol. Biol. 170, 765-776
22. Schwarz, H., Hinz, H. J., Mehlich, A., Tschesche, H., and Wenzel, H. R. (1987) Biochemistry 26, 3544-3551
23. Hurle, M. R., Marks, C. B., Kosen, P. A., Anderson, S., and Kuntz, I. D. (1990) Biochemistry 29, 4410-4419
24. Liu, Y., Breslauer, K., and Anderson, S. (1997) Biochemistry 36, 5323-5335
25. Mumberg, D., Müller, R., and Funk, M. (1994) Nucleic Acids Res. 22, 5767-5768
26. Clements, J. M., Catlin, G. H., Price, M. J., and Edwards, R. M. (1991) Gene 106, 267-271
27. Sambrook, J., and Russell, D. W. (2001) Molecular Cloning: A Laboratory Manual, 3rd Ed, Cold Spring Harbor Laboratory Press, Plainview, NY
28. Doering, D. S., and Matsudaira, P. (1996) Biochemistry 35, 12677-12685
29. Yu, M. H., Weissman, J. S., and Kim, P. S. (1995) J. Mol. Biol. 249, 388-397
30. Kassell, B. (1970) Methods Enzymol. 19, 844-853
31. Edelhoch, H. (1967) Biochemistry 6, 1948-1954
32. Castro, M. J., and Anderson, S. (1996) Biochemistry 35, 11435-11446
33. Makhatadze, G. I., Kim, K. S., Woodward, C., and Privalov, P. L. (1993) Protein Sci. 2, 2028-2036
34. Proba, K., Wörn, A., Honegger, A., and Plückthun, A. (1998) J. Mol. Biol. 275, 245-253
35. Pace, C. N., Grimsley, G. R., Thomson, J. A., and Barnett, B. J. (1988) J. Biol. Chem. 263, 11820-11825
36. Kuroki, R., Inaka, K., Taniyama, Y., Kidokoro, S., Matsushima, M., Kikuchi, M., and Yutani, K. (1992) Biochemistry 31, 8323-8328
37. Rudolph, R., and Lilie, H. (1996) FASEB J. 10, 49-56
38. Fink, A. L. (1998) Folding Des. 3, R9-R23