-
1
-
-
0032553587
-
High-resolution protein design with backbone freedom
-
Harbury, P.B., Plecs, J.J., Tidor, B., Alber, T. & Kim, P.S. (1998) High-resolution protein design with backbone freedom. Science 282, 1462-1467.
-
(1998)
Science
, vol.282
, pp. 1462-1467
-
-
Harbury, P.B.1
Plecs, J.J.2
Tidor, B.3
Alber, T.4
Kim, P.S.5
-
2
-
-
0030779405
-
A designed four helix bundle protein with native-like structure
-
Schafmeister, C.E., LaPorte, S.L., Miercke, L.J. & Stroud, R.M. (1997) A designed four helix bundle protein with native-like structure. Nat. Struct. Biol. 4, 1039-1046.
-
(1997)
Nat. Struct. Biol.
, vol.4
, pp. 1039-1046
-
-
Schafmeister, C.E.1
LaPorte, S.L.2
Miercke, L.J.3
Stroud, R.M.4
-
3
-
-
0033545937
-
Solution structure and dynamics of a de novo designed three-helix bundle protein
-
Walsh, S.T., Cheng, H., Bryson, J.W., Roder, H. & DeGrado, W.F. (1999) Solution structure and dynamics of a de novo designed three-helix bundle protein. Proc. Natl Acad. Sci. USA 96, 5486-5491.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 5486-5491
-
-
Walsh, S.T.1
Cheng, H.2
Bryson, J.W.3
Roder, H.4
DeGrado, W.F.5
-
4
-
-
0032835617
-
De novo design and structural characterization of proteins and metalloproteins
-
DeGrado, W.F., Summa, C.M., Pavone, V., Nastri, F. & Lombardi, A. (1999) De novo design and structural characterization of proteins and metalloproteins. Annu. Rev. Biochem. 68, 779-819.
-
(1999)
Annu. Rev. Biochem.
, vol.68
, pp. 779-819
-
-
DeGrado, W.F.1
Summa, C.M.2
Pavone, V.3
Nastri, F.4
Lombardi, A.5
-
5
-
-
0033775264
-
Molecular Breeding: The natural approach to protein design
-
Ness, J.E., Del Cardayre, S.B., Minshull, J. & Stemmer, W.P. (2001) Molecular Breeding: The natural approach to protein design. Adv. Protein Chem. 55, 261-286.
-
(2001)
Adv. Protein Chem.
, vol.55
, pp. 261-286
-
-
Ness, J.E.1
Del Cardayre, S.B.2
Minshull, J.3
Stemmer, W.P.4
-
6
-
-
0033779402
-
Temperature adaptation of enzymes: Lessons from laboratory evolution
-
Wintrode, P.L. & Arnold, F.H. (2001) Temperature adaptation of enzymes: lessons from laboratory evolution. Adv. Protein Chem. 55, 161-226.
-
(2001)
Adv. Protein Chem.
, vol.55
, pp. 161-226
-
-
Wintrode, P.L.1
Arnold, F.H.2
-
7
-
-
23444436172
-
Protein design by binary patterning of polar and nonpolar amino acids
-
Kametkar, S., Schiffer, J.M., Xiong, H., Babik, J.M. & Hecht, M.H. (1993) Protein design by binary patterning of polar and nonpolar amino acids. Science 262, 1680-1685.
-
(1993)
Science
, vol.262
, pp. 1680-1685
-
-
Kametkar, S.1
Schiffer, J.M.2
Xiong, H.3
Babik, J.M.4
Hecht, M.H.5
-
8
-
-
0035424708
-
Exploring protein interactions by interaction-induced folding of proteins from complementary peptide fragments
-
Michnick, S.W. (2001) Exploring protein interactions by interaction-induced folding of proteins from complementary peptide fragments. Curr. Opin. Struct. Biol. 11, 472-477.
-
(2001)
Curr. Opin. Struct. Biol.
, vol.11
, pp. 472-477
-
-
Michnick, S.W.1
-
9
-
-
0031729179
-
Selecting proteins with improved stability by a phage-based method
-
Sieber, V., Pluckthun, A. & Schmid, F.X. (1998) Selecting proteins with improved stability by a phage-based method. Nat. Biotechnol. 16, 955-960.
-
(1998)
Nat. Biotechnol.
, vol.16
, pp. 955-960
-
-
Sieber, V.1
Pluckthun, A.2
Schmid, F.X.3
-
10
-
-
0031759422
-
Proteolytic selection for protein folding using filamentous bacteriophages
-
Kristensen, P. & Winter, G. (1998) Proteolytic selection for protein folding using filamentous bacteriophages. Fold. Des. 3, 321-328.
-
(1998)
Fold. Des.
, vol.3
, pp. 321-328
-
-
Kristensen, P.1
Winter, G.2
-
11
-
-
0033533503
-
Core-directed protein design. I. An experimental method for selecting stable proteins from combinatorial libraries
-
Finucane, M.D., Tuna, M., Lees, J.H. & Woolfson, D.N. (1999) Core-directed protein design. I. An experimental method for selecting stable proteins from combinatorial libraries. Biochemistry 38, 11604-11612.
-
(1999)
Biochemistry
, vol.38
, pp. 11604-11612
-
-
Finucane, M.D.1
Tuna, M.2
Lees, J.H.3
Woolfson, D.N.4
-
12
-
-
0033533387
-
Core-directed protein design. II. Rescue of a multiply mutated and destabilized variant of ubiquitin
-
Finucane, M.D. & Woolfson, D.N. (1999) Core-directed protein design. II. Rescue of a multiply mutated and destabilized variant of ubiquitin. Biochemistry 38, 11613-11623.
-
(1999)
Biochemistry
, vol.38
, pp. 11613-11623
-
-
Finucane, M.D.1
Woolfson, D.N.2
-
13
-
-
0030992890
-
De novo design of the hydrophobic core of ubiqutiin
-
Lazars, G.A., Desjarlais, J.R. & Handel, T.M. (1997) De novo design of the hydrophobic core of ubiqutiin. Protein Sci. 6, 1167-1178.
-
(1997)
Protein Sci.
, vol.6
, pp. 1167-1178
-
-
Lazars, G.A.1
Desjarlais, J.R.2
Handel, T.M.3
-
14
-
-
0034682869
-
Automatic protein design with all atom force-fields by exact and heuristic optimization
-
Wernisch, L., Hery, S. & Wodak, S.J. (2000) Automatic protein design with all atom force-fields by exact and heuristic optimization. J. Mol. Biol. 301, 713-736.
-
(2000)
J. Mol. Biol.
, vol.301
, pp. 713-736
-
-
Wernisch, L.1
Hery, S.2
Wodak, S.J.3
-
15
-
-
0036310988
-
Origins of the high stability of an in vitro-selected cold-shock protein
-
Martin, A., Kather, I. & Schmid, F.X. (2002) Origins of the high stability of an in vitro-selected cold-shock protein. J. Mol. Biol. 318, 1341-1349.
-
(2002)
J. Mol. Biol.
, vol.318
, pp. 1341-1349
-
-
Martin, A.1
Kather, I.2
Schmid, F.X.3
-
16
-
-
0036398105
-
Directed evolution of barnase stability using proteolytic selection
-
Pedersen, J.S., Otzen, D.E. & Kristensen, P. (2002) Directed evolution of barnase stability using proteolytic selection. J. Mol. Biol. 323, 115-123.
-
(2002)
J. Mol. Biol.
, vol.323
, pp. 115-123
-
-
Pedersen, J.S.1
Otzen, D.E.2
Kristensen, P.3
-
17
-
-
0034730144
-
Novel folded protein domains generated by combinatorial shuffling of polypeptide segments
-
Riechmann, L. & Winter, G. (2000) Novel folded protein domains generated by combinatorial shuffling of polypeptide segments. Proc. Natl Acad. Sci. USA 97, 10068-10073.
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 10068-10073
-
-
Riechmann, L.1
Winter, G.2
-
18
-
-
0036405903
-
Redesign of a four-helix bundle protein by phage display coupled with proteolysis and structural characterization by NMR and X-ray crystallography
-
Chu, R.A., Takei, J., Knowles, J.R., Andrykovitch, M., Pei, W., Kajava, A.V., Steinbach, P., Ji, X. & Bai, Y. (2002) Redesign of a four-helix bundle protein by phage display coupled with proteolysis and structural characterization by NMR and X-ray crystallography. J. Mol. Biol. 323, 253-262.
-
(2002)
J. Mol. Biol.
, vol.323
, pp. 253-262
-
-
Chu, R.A.1
Takei, J.2
Knowles, J.R.3
Andrykovitch, M.4
Pei, W.5
Kajava, A.V.6
Steinbach, P.7
Ji, X.8
Bai, Y.9
-
19
-
-
0023812695
-
Characterization of a helical protein designed from first principles
-
Regan, L. & DeGrado, W.F. (1988) Characterization of a helical protein designed from first principles. Science 241, 976-978.
-
(1988)
Science
, vol.241
, pp. 976-978
-
-
Regan, L.1
DeGrado, W.F.2
-
20
-
-
23444436172
-
Protein design by binary patterning of polar and nonpolar amino acids
-
Kamtekar, S., Schiffer, J.M., Xiong, H., Babik, J.M. & Hecht, M.H. (1993) Protein design by binary patterning of polar and nonpolar amino acids. Science 262, 1680-1685.
-
(1993)
Science
, vol.262
, pp. 1680-1685
-
-
Kamtekar, S.1
Schiffer, J.M.2
Xiong, H.3
Babik, J.M.4
Hecht, M.H.5
-
21
-
-
0029154811
-
Native-like and structurally characterized designed alpha-helical bundles
-
Betz, S.F., Bryson, J.W. & DeGrado, W.F. (1995) Native-like and structurally characterized designed alpha-helical bundles. Curr. Opin. Struct. Biol. 5, 457-463.
-
(1995)
Curr. Opin. Struct. Biol.
, vol.5
, pp. 457-463
-
-
Betz, S.F.1
Bryson, J.W.2
DeGrado, W.F.3
-
22
-
-
0034964196
-
Computer-based redesign of a protein folding pathway
-
Nauli, S., Kuhlman, B. & Baker, D. (2001) Computer-based redesign of a protein folding pathway. Nat. Struct. Biol. 8, 602-605.
-
(2001)
Nat. Struct. Biol.
, vol.8
, pp. 602-605
-
-
Nauli, S.1
Kuhlman, B.2
Baker, D.3
-
23
-
-
0036892410
-
Crystal structures and increased stabilization of the protein G variants with switched folding pathways NuG1 and NuG2
-
Nauli, S., Kuhlman, B., Trong, I.L., Stenkamp, R.E., Teller, D. & Baker, D. (2002) Crystal structures and increased stabilization of the protein G variants with switched folding pathways NuG1 and NuG2. Protein Sci. 11, 2924-2931.
-
(2002)
Protein Sci.
, vol.11
, pp. 2924-2931
-
-
Nauli, S.1
Kuhlman, B.2
Trong, I.L.3
Stenkamp, R.E.4
Teller, D.5
Baker, D.6
-
24
-
-
0031779918
-
Design, structure and stability of a hyperthermophilic protein variant
-
Malakauskas, S.M. & Mayo, S.L., (1998) Design, structure and stability of a hyperthermophilic protein variant. Nat. Struct. Biol. 5, 470-475.
-
(1998)
Nat. Struct. Biol.
, vol.5
, pp. 470-475
-
-
Malakauskas, S.M.1
Mayo, S.L.2
-
25
-
-
0029008590
-
A buried polar interaction imparts structural uniqueness in a designed heterodimeric coiled coil
-
Lumb, K.J. & Kim, P.S. (1995) A buried polar interaction imparts structural uniqueness in a designed heterodimeric coiled coil. Biochemistry 34, 8642-8648.
-
(1995)
Biochemistry
, vol.34
, pp. 8642-8648
-
-
Lumb, K.J.1
Kim, P.S.2
-
26
-
-
0037108164
-
Populating partially unfolded forms by hydrogen exchange-directed protein engineering
-
Takei, J., Pei, W., Vu, D. & Bai, Y. (2002) Populating partially unfolded forms by hydrogen exchange-directed protein engineering. Biochemistry 41, 12308-12312.
-
(2002)
Biochemistry
, vol.41
, pp. 12308-12312
-
-
Takei, J.1
Pei, W.2
Vu, D.3
Bai, Y.4
-
27
-
-
0030793767
-
De novo protein design: Fully automated sequence selection
-
Dahiyat, B.I. & Mayo, S.L. (1997) De novo protein design: fully automated sequence selection. Science 278, 82-87.
-
(1997)
Science
, vol.278
, pp. 82-87
-
-
Dahiyat, B.I.1
Mayo, S.L.2
-
28
-
-
0035896029
-
Generalized dead-end elimination algorithms make large-scale protein side-chain structure prediction tractable: Implications for protein design and structural genomics
-
Looger, L.L. & Hellinga, H.W. (2001) Generalized dead-end elimination algorithms make large-scale protein side-chain structure prediction tractable: implications for protein design and structural genomics. J. Mol. Biol. 307, 429-445.
-
(2001)
J. Mol. Biol.
, vol.307
, pp. 429-445
-
-
Looger, L.L.1
Hellinga, H.W.2
-
29
-
-
0028858499
-
De novo design of the hydrophobic cores of protiens
-
Desjarlais, J.R. & Handel, T.M. (1995) De novo design of the hydrophobic cores of protiens. Protein Sci. 4, 2006-2018.
-
(1995)
Protein Sci.
, vol.4
, pp. 2006-2018
-
-
Desjarlais, J.R.1
Handel, T.M.2
-
30
-
-
0028048679
-
Core-packing constraints, hydrophobicity and protein design
-
Baldwin, E.P. & Matthews, B.W. (1994) Core-packing constraints, hydrophobicity and protein design. Curr. Opin. Biotechnol. 5, 396-402.
-
(1994)
Curr. Opin. Biotechnol.
, vol.5
, pp. 396-402
-
-
Baldwin, E.P.1
Matthews, B.W.2
-
31
-
-
0030762021
-
Coupling backbone flexibility and amino acid sequence selection in protein design
-
Su, A. & Mayo, S.L. (1997) Coupling backbone flexibility and amino acid sequence selection in protein design. Protein Sci. 6, 1701-1707.
-
(1997)
Protein Sci.
, vol.6
, pp. 1701-1707
-
-
Su, A.1
Mayo, S.L.2
-
32
-
-
0033516509
-
Side-chain and backbone flexibility in protein core design
-
Desjarlais, J.R. & Handel, T.M. (1999) Side-chain and backbone flexibility in protein core design. J. Mol. Biol. 289, 305-318.
-
(1999)
J. Mol. Biol.
, vol.289
, pp. 305-318
-
-
Desjarlais, J.R.1
Handel, T.M.2
-
33
-
-
0033536602
-
Evolutionarily conserved pathways of energetic connectivity in protein families
-
Lockless, S.W. & Ranganathan, R. (1999) Evolutionarily conserved pathways of energetic connectivity in protein families. Science 286, 295-299.
-
(1999)
Science
, vol.286
, pp. 295-299
-
-
Lockless, S.W.1
Ranganathan, R.2
-
34
-
-
0036667733
-
Knowledge-based potential functions in protein design
-
Russ, W.P. & Ranganathan, R. (2002) Knowledge-based potential functions in protein design. Curr. Opin. Struct. Biol. 12, 447-452.
-
(2002)
Curr. Opin. Struct. Biol.
, vol.12
, pp. 447-452
-
-
Russ, W.P.1
Ranganathan, R.2
-
35
-
-
0036667732
-
Energy estimation in protein design
-
Mendes, J., Guerois, R. & Serrano, L. (2002) Energy estimation in protein design. Curr. Opin. Struct. Biol. 12, 441-446.
-
(2002)
Curr. Opin. Struct. Biol.
, vol.12
, pp. 441-446
-
-
Mendes, J.1
Guerois, R.2
Serrano, L.3
|