Effect of flavonoids on glutathione level, lipid peroxidation and cytochrome P450 CYP1A1 expression in human laryngeal carcinoma cell lines

Food Technology and Biotechnology

Volumn 45, Issue 1, 2007, Pages 69-79

  Durgo, Ksenija ^a   Vuković, Lidija ^b   Rusak, Gordana ^c   Osmak, Maja ^b   Čolić, Jasna Franekić ^a  

^a UNIVERSITY OF ZAGREB   (Croatia)

^b RUDER BO KOVI INSTITUTE   (Croatia)

^c UNIVERSITY OF ZAGREB   (Croatia)

Author keywords

Cytochrome 1A1; Cytotoxicity; Flavonoids; Glutathione; Lipid peroxidation; Tumor cells

Indexed keywords

ANTI-OXIDANT ACTIVITIES; BIOCHEMICAL PATHWAY; BIOLOGICAL EFFECTS; CELL MEMBRANE PERMEABILITY; GLUTATHIONES; LARYNGEAL CARCINOMAS; LIPID PEROXIDATION; TUMOR CELLS;

CELL CULTURE; CELL MEMBRANES; CYTOTOXICITY; FREE RADICALS; LIPIDS; OXIDATIVE STRESS; PEPTIDES; PHENOLS;

FLAVONOIDS;

EID: 33947595267     PISSN: 13309862     EISSN: 13342606     Source Type: Journal    
DOI: None     Document Type: Article

References (38)

1. L.G. Korkina, I.B. Afanas'ev, Antioxidant and chelating properties of flavonoids, Adv. Pharmacol. 38 (1997) 151-163.
2. S.A. Aherne, N.M. O'Brien, Dietary flavonols: Chemistry, food content and metabolism, Nutrition, 18 (2002) 75-81.
3. A.J. Day, M.R.A. Morgan, M.J.C. Rhodes, G. Williamson: The First Step in the Metabolism of Flavonoid Glycosides. In: Dietary Anticarcinogens and Antimutagens: Chemical and Biological Aspects, I.T. Johnson, G.R. Fenwick (Eds.), Royal Chemistry Society, Cambridge, UK (2000) p. 55.
4. J.B. Harborne: Nature, Distribution, and Function of Plant Flavonoids. In: Plant Flavonoids in Biology and Medicine: Biochemical, Pharmacological and Structure-Activity Relationships, V. Cody, E. Middleton, J.B. Harborne (Eds.), Alan R. Liss, New York, USA (1986) p. 15.
5. P. Hodek, P. Trefil, M. Stiborova, Flavonoids - Potent and versatile biologically active compounds interacting with cytochromes P450, Chem. Biol. Interact. 139 (2002) 1-21.
6. N.H.P. Cnubben, I.M.C.M. Rietjens, H. Wortelboer, J. van Zanden, P.J. van Bladeren, The interplay of glutathione-related processes in antioxidant defense, Environ. Toxicol. Pharmacol. 10 (2001) 141-152.
7. L. Cipak, E. Berceliova, H. Paulikova, Effects of flavonoids on glutathione and glutathione-related enzymes in cysplatin-treated L1210 leukemia cells, Neoplasma, 50 (2003) 443-446.
8. A.W. Boots, J.M. Balik, A. Bast, G.R.M.M. Haenen, The reversibility of the glutathionyl-quercetin adduct spreads oxydised quercetin-induced toxicity, Biochem. Biophys. Res. Commun. 338 (2005) 923-929.
9. N.M. O'Brien, J.A. Woods, S.A. Aherne, Y.C. O'Callaghan, Cytotoxicity, genotoxicity and oxidative reactions in cell culture models: Modulatory effects of phytochemicals, Biochem. Soc. Trans. 28 (2000) 22-26.
10. J. Timbrell: Primary Events: Lipid Peroxidation. In: Principles of Biochemical Toxicology, J. Timbrell (Ed.), Taylor and Francis, London, UK (2000) pp. 204-213.
11. J. Torel, J. Cillard, Antioxidant activity of flavonoids and reactivity with peroxy radical, Phytochemistry, 25 (1986) 383-387.
12. J. Terao, M. Piskula, Q. Yao, Protective effect of epicatechin, epicatechin gallate and quercetin on lipid peroxidation in phospholipid bilayers, Arch. Biochem. Biophys. 308 (1994) 278-284.
13. 4 induced microsomal lipid peroxidation, Experientia, 47 (1991) 195-199.
14. M. Osmak, Collateral resistance or sensitivity of human larynx carcinoma HEp2 cells resistant to cis-dichlorodiammineplatinum(II) or vincristine sulfate, Neoplasma, 39 (1992) 197-202.
15. M. Osmak, L. Beketić-Orešković, M. Matulić, J. Sorić, Resistance of human larynx carcinoma cells to cisplatin, gamma irradiation and methotrexate do not involve overexpression of c-myc or c-Ki-ras oncogenes, Mutat. Res. 303 (1993) 113-120.
16. L. Beketić-Orešković, M. Osmak, Human larynx carcinoma cells resistant to cis-diamminedichloroplatinum(II): Cross-resistance pattern, Neoplasma, 41 (1994) 171-176.
17. L. Beketić-Orešković, M. Osmak, Modulation of resistance to cis-diamminedichloroplatinum(II) by amphotericin B and aphidicolin in human larynx carcinoma cells, Cancer Chemother. Pharm. 35 (1995) 327-333.
18. L. Beketić-Orešković, M. Jakšić, S. Orešković, M. Osmak, Hyperthermic modulation of resistance to cis-diammine-dichloroplatinum(II) in human larynx carcinoma cells, Int. J. Hyperth. 13 (1997) 205-214.
19. M. Osmak, D. Nikšić, A. Brozović, A. Ambriović-Ristov, I. Vrhovec, J. Škrk, Drug resistant tumor cells have increased levels of tumor markers for invasion and metastasis, Anti-cancer Res. 19 (1999) 3193-3198.
20. 3 and cox-sackie adenovirus receptor, Int. J. Cancer, 110 (2004) 660-667.
21. G. Mickish, S. Fajta, G. Keilhauer, E. Schlick, R. Tschada, P. Alken, Chemosensitivity testing of primary human renal cell carcinoma by tetrazolium based microculture assay (MTT), Urol. Res. 18 (1990) 131-136.
22. F. Tietze, Enzymatic method for quantitative determination of nanogram amounts of total and oxidized glutathione: Applications to mammalian blood and other tissues, Anal. Biochem. 27 (1969) 502-522.
23. M.M. Bradford, A rapid and sensitive method for the quantification of microgram quantities of protein utilising the principle of protein-dye binding, Anal. Biochem. 72 (1976) 248-254.
24. C. Cereser, S. Boget, P. Parvaz, A. Revol, Thiram-induced cytotoxicity is accompanied by a rapid and drastic oxidation of reduced glutathione with consecutive lipid peroxidation and cell death, Toxicology, 163 (2001) 153-162.
25. S. McCarthy, M. Somayajulu, M. Sikorska, H. Borowy-Borowski, S. Pandey, Paraquat induces oxidative stress and neuronal cell death; Neuroprotection by water soluble coenzyme Q-10, Toxicol. Appl. Pharm. 201 (2004) 21-31.
26. E. Hurna, S. Hurna, Influence of zinc on cadmium induced cytotoxicity in cultured rat liver cells, J. Trace Microprobe Tech. 16 (1998) 437-444.
27. O.H. Lowry, N.J. Rosenbrough, A.L. Farr, R.J. Randall, Protein measurement with the Folin phenol reagent, J. Biol. Chem. 193 (1951) 265-275.
28. G. Rusak, H.O. Gutzeit, J. Ludwig Müller, Structurally related flavonoids with antioxidative properties differentially affect cell cycle progression and apoptosis of human acute leukaemia cells, Nutr. Res. 25 (2005) 141-153.
29. G. Rusak, H.O. Gutzeit, J. Ludwig-Müller, Effects of structurally related flavonoids on hsp gene expression in human promyeloid leukaemia cells, Food Technol. Biotechnol. 40 (2002) 267-273.
30. T. Hirano, M. Gotoh, K. Oka, Natural flavonoids and lignans are potent cytostatic agents against human leukemic HL-60 cells, Life. Sci. 55 (1994) 1061-1069.
31. G. Scambia, F. Ranelletti, P.B. Panici, M. Piantelli, G. Bonanno, R. De Vincenzo, G. Ferrandina, N. Maggiano, N. Capelli, S. Mancuso, Inhibitory effect of quercetin on primary ovarian and endometrial cancers and synergistic antiproliferative activity with cis-diamminedichloroplatinum (II), Gynecol. Oncol. 45 (1992) 13-19.
32. L. Beketić-Orešković, M. Osmak, M. Jakšić, Human larynx carcinoma cells resistant to cis-diamminedichloroplatinum(II): Mechanisms involved in resistance, Neoplasma, 41 (1994) 163-169.
33. S. Devi Priya, C.S. Shyamala Devi, Protective effect of quercetin in cisplatin-induced cell injury in the rat kidney, Indian J. Pharmacol. 31 (1999) 422-426.
34. S.N. Pattipati, A. Singh, S.K. Kulkarni, Reversal of reserpine-induced orofacial dyskinesia and cognitive disfunction by quercetin, Pharmacology, 70 (2004) 59-67.
35. N. Cotelle, Role of flavonoids in oxidative stress, Curr. Top. Med. Chem. 1 (2001) 569-590.
36. K. Shimoi, H. Okada, J. Kaneko, M. Furugori, T. Goda, S. Takase, M. Suzuki, Y. Hara, N. Kinae: Bioavailability and Antioxidant Properties of Luteolin. In: Natural Antioxidants and Anticarcinogens in Nutrition, Health and Disease, J.T. Kumpulainen, J.T. Salonen (Eds.), Royal Society of Chemistry, Finland (1998) pp. 166-174.
37. M.S. Kumar, M.K. Unnikrishnan, S. Patra, K. Murthy, K.K. Srinivasan, Naringin and naringenin inhibit nitrite-inuced methemoglobin formation, Pharmazie, 58 (2003) 564-566.
38. J.F. Young, S.E. Nielsen, J. Haraldsdotir, B. Daneshvar, S.T. Lauridsen, P. Knuthsen, A. Crozier, B. Sandstörm, L.O. Dragsted: Effect of Fruit Intake on Urinary Quercetin Excretion and Biomarkers of Antioxidative Status. In: Natural Antioxidants and Anticarcinogens in Nutrition, Health and Disease, J.T. Kumpulainen, J.T. Salonen (Eds.), Royal Society of Chemistry, Finland (1998) pp. 193-203.