Lactobacillus acidophilus 74-2 and butyrate induce cyclooxygenase (COX)-1 expression in gastric cancer cells

Immunopharmacology and Immunotoxicology

Volumn 30, Issue 3, 2008, Pages 503-518

  Mahkonen, Anna ^a   Putaala, Heli ^b   Mustonen, Harri ^a   Rautonen, Nina ^b   Puolakkainen, Pauli ^a  

^a HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

^b Danisco Finland Oy   (Finland)

Author keywords

Butyrate; Cyclo Oxygenases (COXs); Gastric Cancer; Osmotic Stress; Probiotics

Indexed keywords

BUTYRIC ACID; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; PROBIOTIC AGENT;

ARTICLE; BACTERIAL STRAIN; BIFIDOBACTERIUM ANIMALIS; BIFIDOBACTERIUM LACTIS 420; CANCER CELL CULTURE; CELL FREE SYSTEM; CELL PROTECTION; CONTROLLED STUDY; CULTURE MEDIUM; HUMAN; HUMAN CELL; HYPEROSMOLARITY; LACTOBACILLUS ACIDOPHILUS; LACTOBACILLUS ACIDOPHILUS 74 2; METASTASIS; OSMOTIC STRESS; PREDICTION; PRIORITY JOURNAL; PROGNOSIS; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; STOMACH ADENOCARCINOMA; STOMACH PROTECTION; SUPERNATANT; UPREGULATION;

ADENOCARCINOMA; BIFIDOBACTERIUM; BUTYRATES; CELL LINE, TUMOR; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; ENZYME INDUCTION; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; LACTOBACILLUS ACIDOPHILUS; NEOPLASM METASTASIS; OSMOTIC PRESSURE; POLYMERASE CHAIN REACTION; PROBIOTICS; RNA, MESSENGER; SALINE SOLUTION, HYPERTONIC; STOMACH NEOPLASMS; TIME FACTORS;

BIFIDOBACTERIUM ANIMALIS SUBSP. LACTIS; LACTOBACILLUS ACIDOPHILUS;

EID: 48349127439     PISSN: 08923973     EISSN: 15322513     Source Type: Journal    
DOI: 10.1080/08923970802135229     Document Type: Article

References (44)

1. Gill, H.S.; Guarner, F.. Probiotics and human health: a clinical perspective. Postgrad. Med. J. 80, 516-526, 2004.
2. Commane, D.; Hughes, R; Shortt, C.; Rowland I. The potential mechanisms involved in the anti-carcinogenic action of probiotics. Mutat. Res. 591, 276-289, 2005.
3. Rafter, J. Probiotics and colon cancer. Best Pract. Res. Clin. Gastroenterol. 17, 849-859, 2003.
4. Burns, A.J.; Rowland, I.R. Antigenotoxicity of probiotics and prebiotics on faecal water-induced DNA damage in human colon adenocarcinoma cells. Mutat. Res. 551, 233-243, 2004.
5. Oberreuther-Moschner, D.L.; Jahreis, G.; Rechkemmer, G.; Pool-Zobel, B.L. Dietary intervention with the probiotics Lactobacillus acidophilus 145 and Bifidobacterium longum 913 modulates the potential of human faecal water to induce damage in HT29clone19A cells. Br. J. Nutr. 91, 925-932, 2004.
6. Simmons, D.L.; Botting, R.M.; Hla, T. Cyclooxygenase isozymes: The biology of prostaglandin synthesis and inhibition. Pharmacol. Rev. 56, 387-437, 2004.
7. Xie, W.L.; Chipman, J.G.; Robertson, D.L.; Erikson, R.L.; Simmons, D.L. Expression of a mitogen-responsive gene encoding prostaglandin synthase is regulated by mRNA splicing. Proc. Natl .Acad. Sci. U. S. A. 88, 2692-6, 1991.
8. DuBois, R.N.; Tsujii, M.; Bishop, P.; Awad, J.A.; Makita, K.; Lanahan, A. Cloning and characterization of a growth factor-inducible cyclo-oxygenase gene from rat intestinal epithelial cells. Am. J. Physiol. 266, G822-G827, 1994.
9. Arias-Negrete, S.; Keller, K.; Chadee, K. Proinflammatory cytokines regulate cyclooxygenase-2 mRNA expression in human macrophages. Biochem. Biophys. Res. Commun. 208, 582-589, 1995.
10. Moeckel, G.W.; Zhang, L.; Fogo, A.B.; Hao, C.M.; Pozzi, A.; Breyer, M.D. COX2 activity promotes organic osmolyte accumulation and adaptation of renal medullary interstitial cells to hypertonic stress. J. Biol. Chem. 278, 19352-19357, 2003.
11. Moran, E.M. Epidemiological and clinical aspects of nonsteroidal anti-inflammatory drugs and cancer risks. J. Environ. Pathol. Toxicol. Oncol. 21, 193-201, 2002.
12. Sinicrope, F.A. Targeting cyclooxygenase-2 for prevention and therapy of colorectal cancer. Mol. Carcinog .45, 447-454, 2006.
13. Qin, N.; Zhang, S.P.; Reitz, T.L.; Mei, J.M.; Flores, C.M. Cloning, expression, and functional characterization of human cyclooxygenase-1 splicing variants: Evidence for intron 1 retention. J. Pharmacol. Exp. Ther. 315, 1298-1305, 2005.
14. Chandrasekharan, N.V.; Dai, H.; Roos, K.L.; Evanson, N.K.; Tomsik, J.; Elton, T.S.; Simmons, D.L. COX-3, a cyclooxygenase-1 variant inhibited by acetaminophen and other analgesic/antipyretic drugs: cloning, structure, and expression. Proc. Natl. Acad. Sci. U. S. A. 99, 13926-31, 2002.
15. Nurmi, J.T.; Puolakkainen, P.A.; Rautonen, N.E. Intron 1 retaining cyclooxygenase 1 splice variant is induced by osmotic stress in human intestinal epithelial cells. Prostaglandins Leukot. Essent. Fatty Acids 73, 343-350, 2005.
16. Cummings, J.H.; Macfarlane, G.T. Role of intestinal bacteria in nutrient metabolism. J. Parenter. Enteral. Nutr. 21, 357-365, 1997.
17. Tong, X.; Yin, L.; Giardina, C. Butyrate suppresses Cox-2 activation in colon cancer cells through HDAC inhibition. Biochem. Biophys. Res. Commun. 317, 463-71, 2004.
18. Nurmi, J.T.; Puolakkainen, P.A.; Rautonen, N.E. Bifidobacterium Lactis sp. 420 up-regulates cyclooxygenase (Cox)-1 and down-regulates Cox-2 gene expression in a Caco-2 cell culture model. Nutr. Cancer 51, 83-92, 2005.
19. Barranco, S.C.; Townsend, C.M., Jr.; Quraishi, M.A.; Burger, N.L.; Nevill, H.C.; Howell, K.H.; Boerwinkle, W.R. Heterogeneous responses of an in vitro model of human stomach cancer to anticancer drugs. Invest. New Drugs 1, 117-127, 1983.
20. Park, J.G.; Frucht, H.; LaRocca, R.V.; Bliss, D.P., Jr.; Kurita, Y.; Chen, T.R.; Henslee, J.G.; Trepel, J.B.; Jensen, R.T.; Johnson, B.E. Characteristics of cell lines established from human gastric carcinoma. Cancer. Res. 50, 2773-2780, 1990.
21. Apajalahti, J.H.; Kettunen, H.; Kettunen, A.; Holben, W.E.; Nurminen, P.H.; Rautonen, N.; Mutanen, M. Culture-independent microbial community analysis reveals that insulin in the diet primarily affects previously unknown bacteria in the mouse cecum. Appl. Environ. Microbiol. 68, 4986-4995, 2002.
22. Hirayama, K.; Rafter, J. The role of probiotic bacteria in cancer prevention. Microbes Infect. 2, 681-686, 2000.
23. Geier, M.S.; Butler, R.N.; Howarth, G.S. Probiotics, prebiotics and synbiotics: A role in chemoprevention for colorectal cancer? Cancer Biol. Ther. 5, 1265-1269, 2006.
24. Ljungh, A; Wadstrom, T. Lactic acid bacteria as probiotics. Curr. Issues Intest. Microbiol. 7, 73-89, 2006.
25. Myllyluoma, E.; Ahlroos, T.; Veijola L.; Rautelin, H.; Tynkkynen, S.; Korpela, R. Effects of anti-Helicobacter pylori treatment and probiotic supplementation on intestinal microbiota. Int. J. Antimicrob. Agents 29, 66-72, 2007.
26. Myllyluoma, E.; Veijola, L.; Ahlroos T.; Tynkkynen, S.; Kankuri, E.; Vapaatalo, H.; Rautelin, H.; Korpela, R. Probiotic supplementation improves tolerance to Helicobacter pylori eradication therapy - A placebo-controlled, double-blind randomized pilot study. Aliment Pharmacol. Ther. 21, 1263-1272, 2005.
27. Putaala, H.; Salusjärvi, T.; Nordström, M.; Saarinen, M.; Ouwehand, A.; Bech-Hansen, E.; Rautonen, N.. Effect of four probiotic strains and Escherichia coli O157:H7 on tight junction integrity and cyclo-oxygenase expression in differentiated Caco-2 cells. submitted for publication, 2008.
28. Miller, S.J. Cellular and physiological effects of short-chain fatty acids. Mini. Rev. Med. Chem. 4, 839-45, 2004.
29. Litvak, D.A.; Hwang, K.O.; Evers, B.M.; Townsend, C.M., Jr.. Induction of apoptosis in human gastric cancer by sodium butyrate. Anticancer Res. 20, 779-784, 2000.
30. Zhang, Z.H.; Ouyang, Q.; Gan, H.T. Targeting cyclooxygenase-2 with sodium butyrate and NSAIDs on colorectal adenoma/carcinoma cells. World J. Gastroenterol. 10, 2954-7, 2004.
31. Shi, H.; Xu, J.M.; Hu, N.Z.; Xie, H.J. Prognostic significance of expression of cyclooxygenase-2 and vascular endothelial growth factor in human gastric carcinoma. World J .Gastroenterol. 9, 1421-1426, 2003.
32. Mrena, J.; Wiksten, J.P.; Thiel, A.; Kokkola, A.; Pohjola, L.; Lundin, J.; Nordling, S.; Ristimaki, A.; Haglund, C. Cyclooxygenase-2 is an independent prognostic factor in gastric cancer and its expression is regulated by the messenger RNA stability factor HuR. Clin. Cancer Res. 11, 7362-7368, 2005.
33. Saukkonen, K.; Rintahaka, J.; Sivula, A.; Buskens, C.J.; van Rees, B.P.; Rio, M.C.; Haglund, C.; van Lanschot, J.J.; Offerhaus, G.J.; Ristimaki, A. Cyclooxygenase-2 and gastric carcinogenesis. APMIS 111, 915-925, 2003.
34. Masferrer, J.L.; Leahy, K.M.; Koki, A.T.; Zweifel, B.S.; Settle, S.L.; Woerner, B.M.; Edwards, D.A.; Flickinger, A.G.; Moore, R.J.; Seibert, K. Antiangiogenic and antitumor activities of cyclooxygenase-2 inhibitors. Cancer Res. 60, 1306-1311, 2000.
35. Tsujii, M.; Kawano, S.; DuBois, R.N. Cyclooxygenase-2 expression in human colon cancer cells increases metastatic potential. Proc. Natl. Acad. Sci. U. S. A. 94, 3336-3340, 1997.
36. Tsujii, M; Kawano, S; Tsuji, S; Sawaoka, H; Hori, M; DuBois, RN. Cyclooxygenase regulates angiogenesis induced by colon cancer cells. Cell 93, 705-716, 1998.
37. Lin, MT; Zuon, CY; Chang, CC; Chen, ST; Chen, CP; Lin, BR; Wang, MY; Jeng, YM; Chang, K.J.; Lee, P.H.; Chen, W.J.; Kuo, M.L. Cyr61 induces gastric cancer cell motility/invasion via activation of the integrin/nuclear factor-kappaB/cyclooxygenase-2 signaling pathway. Clin. Cancer Res. 11, 5809-5820, 2005.
38. Oshima, M.; Dinchuk, J.E.; Kargman, S.L.; Oshima, H.; Hancock, B.; Kwong, E.; Trzaskos, J.M.; Evans, J.F.; Taketo, M.M. Suppression of intestinal polyposis in Apc delta716 knockout mice by inhibition of cyclooxygenase 2 (COX-2). Cell 87, 803-809, 1996.
39. Giardiello, F.M.; Hamilton, S.R.; Krush, A.J.; Piantadosi, S.; Hylind, L.M.; Celano, P.; Booker, S.V.; Robinson, C.R.; Offerhaus, G.J. Treatment of colonic and rectal adenomas with sulindac in familial adenomatous polyposis. N. Engl. J. Med. 328, 1313-1316, 1993.
40. Kune, G.A.; Kune, S.; Watson, L.F. Colorectal cancer risk, chronic illnesses, operations, and medications: Case control results from the Melbourne Colorectal Cancer Study. Cancer Res. 48, 4399-4404, 1988.
41. Zaridze, D.; Borisova, E.; Maximovitch, D.; Chkhikvadze, V. Aspirin protects against gastric cancer: Results of a case-control study from Moscow, Russia. Int. J. Cancer 82, 473-476, 1999.
42. Gonzalez-Perez, A.; Garcia Rodriguez, L.A.; Lopez-Ridaura, R. Effects of non-steroidal anti-inflammatory drugs on cancer sites other than the colon and rectum: a meta-analysis. BMC Cancer 3, 28, 2003.
43. Wambura, C.; Aoyama, N.; Shirasaka, D.; Sakai, T.; Ikemura, T.; Sakashita, M.; Maekawa, S.; Kuroda, K.; Inoue, T.; Ebara, S.; Miyamoto, M.; Kasuga, M. Effect of Helicobacter pylori-induced cyclooxygenase-2 on gastric epithelial cell kinetics: Implication for gastric carcinogenesis. Helicobacter 7, 129-138, 2002.
44. Sung, J.J.; Leung, W.K.; Go, M.Y.; To, K.F..; Cheng, A.S.; Ng, E.K.; Chan, F.K. Cyclooxygenase-2 expression in Helicobacter pylori-associated premalignant and malignant gastric lesions. Am. J. Pathol. 157, 729-735, 2000.