Activation of microglia by endotoxin suppresses the secretion of glial cell line-derived neurotrophic factor (GDNF) through the action of protein kinase Cα (PKCα) and mitogen-activated protein kinases (MAPKs)

Journal of Neuroscience Research

Volumn 86, Issue 9, 2008, Pages 1959-1971

  Matsushita, Yuichi ^a   Nakajima, Kazuyuki ^a,b   Tohyama, Yoko ^a   Kurihara, Tadashi ^a   Kohsaka, Shinichi ^b  

^a SOKA UNIVERSITY   (Japan)

^b NATIONAL INSTITUTE OF NEUROSCIENCE   (Japan)

Author keywords

GDNF; Microglia; Secretion; Signal transduction

Indexed keywords

ENDOTOXIN; GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR; LIPOPOLYSACCHARIDE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN KINASE C ALPHA; STRESS ACTIVATED PROTEIN KINASE;

ARTICLE; CELL ACTIVATION; CELL CULTURE; CULTURE MEDIUM; ENZYME ACTIVITY; IMMUNOBLOTTING; MICROGLIA; MOLECULAR SIZE; PRIORITY JOURNAL; PROTEIN SECRETION; PROTEIN SYNTHESIS; SIGNAL TRANSDUCTION;

ACTINS; ANIMALS; ANIMALS, NEWBORN; BRAIN; BRAIN-DERIVED NEUROTROPHIC FACTOR; DNA PRIMERS; ENDOTOXINS; ENZYME INHIBITORS; GLIAL CELL LINE-DERIVED NEUROTROPHIC FACTOR; IMMUNOHISTOCHEMISTRY; LIPOPOLYSACCHARIDES; MICROGLIA; MITOGEN-ACTIVATED PROTEIN KINASES; NERVE GROWTH FACTORS; PROTEIN KINASE C-ALPHA; RATS; TETRADECANOYLPHORBOL ACETATE;

EID: 48249138170     PISSN: 03604012     EISSN: 10974547     Source Type: Journal    
DOI: 10.1002/jnr.21657     Document Type: Article

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