Elevated oxidative stress and sensorimotor deficits but normal cognition in mice that cannot synthesize ascorbic acid

Journal of Neurochemistry

Volumn 106, Issue 3, 2008, Pages 1198-1208

  Harrison, Fiona E ^a,b   Yu, Sarah S ^a   Van Den Bossche, Kristen L ^a   Li, Liying ^b   May, James M ^b   McDonald, Michael P ^a,b,c  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b VANDERBILT UNIVERSITY   (United States)

^c UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

Author keywords

Alzheimer's disease; Ascorbic acid; Cognition; Mice; Motor deficits; Oxidative stress

Indexed keywords

ASCORBIC ACID; F4 NEUROPROSTANE; GULONOLACTONE OXIDASE; ISOPROSTANE DERIVATIVE;

ALZHEIMER DISEASE; ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN LEVEL; C57BL 6 MOUSE; COGNITION; CONTROLLED STUDY; KNOCKOUT MOUSE; LIPID PEROXIDATION; MEMORY DISORDER; MOTOR PERFORMANCE; NONHUMAN; OXIDATIVE STRESS; PARKINSON DISEASE; PRIORITY JOURNAL; SCURVY; SENSORIMOTOR NEUROPATHY; SURVIVAL; TASK PERFORMANCE;

ANIMALS; ASCORBIC ACID; ASCORBIC ACID DEFICIENCY; COGNITION; FEMALE; L-GULONOLACTONE OXIDASE; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MOTOR ACTIVITY; MOTOR SKILLS DISORDERS; OXIDATIVE STRESS; PSYCHOMOTOR PERFORMANCE;

GULO; MUS;

EID: 48249123821     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2008.05469.x     Document Type: Article

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