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Volumn 8, Issue 11, 2008, Pages 937-953

Overview of experimental and conventional pharmacological approaches in the treatment of sleep and wake disorders

Author keywords

CNS; Excessive daytime sleepiness; Hypothalamus; Insomnia; Sleep

Indexed keywords

ALPHA AMINO 3 HYDROXY 5 METHYL 4 ISOXAZOLEPROPIONIC ACID; ALPRAZOLAM; BARBITURIC ACID DERIVATIVE; BENZODIAZEPINE; BROMPHENIRAMINE; CLONAZEPAM; CX 717; DIAZEPAM; DIMENHYDRINATE; DIMETAPP; DIPHENHYDRAMINE; DOXYLAMINE; ESTAZOLAM; GLUTAMATE RECEPTOR AGONIST; HISTAMINE H3 RECEPTOR ANTAGONIST; HORMONE RECEPTOR BLOCKING AGENT; MELATONIN DERIVATIVE; MIDAZOLAM; NYQUIL; OREXIN ANTAGONIST; OXAZEPAM; OXYBATE SODIUM; PARACETAMOL; PICROTOXIN; PROSTAGLANDIN D2; RAMELTEON; SEROTONIN 2A ANTAGONIST; SEROTONIN ANTAGONIST; SINGLET; TEMAZEPAM; TRAZODONE; TROPISETRON; UNINDEXED DRUG; ZALEPLON; ZOLPIDEM; ZOLPIDEM TARTRATE;

EID: 48249105817     PISSN: 15680266     EISSN: None     Source Type: Journal    
DOI: 10.2174/156802608784936755     Document Type: Review
Times cited : (15)

References (108)
  • 1
    • 34548493708 scopus 로고    scopus 로고
    • Behavioral and physiological consequences of sleep restriction
    • Banks, S.; Dinges, D.F. Behavioral and physiological consequences of sleep restriction. J. Clin. Sleep Med. 2007, 3(5), 519-28.
    • (2007) J. Clin. Sleep Med , vol.3 , Issue.5 , pp. 519-528
    • Banks, S.1    Dinges, D.F.2
  • 2
    • 0019473135 scopus 로고
    • Cumulative effects of sleep restriction on daytime sleepiness
    • Carskadon, M.A.; Dement, W.C. Cumulative effects of sleep restriction on daytime sleepiness. Psychophysiology 1981, 18(2)107-13.
    • (1981) Psychophysiology , vol.18 , Issue.2 , pp. 107-113
    • Carskadon, M.A.1    Dement, W.C.2
  • 3
    • 34248998491 scopus 로고    scopus 로고
    • Obstructive sleep apnea, daytime sleepiness, and type 2 diabetes
    • Chasens, E.R. Obstructive sleep apnea, daytime sleepiness, and type 2 diabetes. Diabetes Educ. 2007, 33(3), 475-82.
    • (2007) Diabetes Educ , vol.33 , Issue.3 , pp. 475-482
    • Chasens, E.R.1
  • 5
    • 27544452392 scopus 로고    scopus 로고
    • Disorders of glucose metabolism in sleep apnea
    • Punjabi, N.M.; Polotsky, V.Y. Disorders of glucose metabolism in sleep apnea. J. Appl. Physiol. 2005, 99(5), 1998-2007.
    • (2005) J. Appl. Physiol , vol.99 , Issue.5 , pp. 1998-2007
    • Punjabi, N.M.1    Polotsky, V.Y.2
  • 6
    • 27544478983 scopus 로고    scopus 로고
    • Sleep loss: A novel risk factor for insulin resistance and Type 2 diabetes
    • Spiegel, K.; Knutson, K.; Leproult, R.; Tasali, E.; Van Cauter, E. Sleep loss: A novel risk factor for insulin resistance and Type 2 diabetes. J. Appl. Physiol. 2005, 99(5), 2008-19.
    • (2005) J. Appl. Physiol , vol.99 , Issue.5 , pp. 2008-2019
    • Spiegel, K.1    Knutson, K.2    Leproult, R.3    Tasali, E.4    Van Cauter, E.5
  • 8
    • 0020368354 scopus 로고
    • A two process model of sleep regulation
    • Borbely, A.A. A two process model of sleep regulation. Hum. Neurobiol. 1982, 1(3), 195-204.
    • (1982) Hum. Neurobiol , vol.1 , Issue.3 , pp. 195-204
    • Borbely, A.A.1
  • 9
    • 0027453277 scopus 로고
    • Effect of SCN lesions on sleep in squirrel monkeys: Evidence for opponent processes in sleep-wake regulation
    • Edgar, D.M.; Dement, W.C.; Fuller, C.A. Effect of SCN lesions on sleep in squirrel monkeys: Evidence for opponent processes in sleep-wake regulation. J. Neurosci. 1993, 13(3), 1065-79.
    • (1993) J. Neurosci , vol.13 , Issue.3 , pp. 1065-1079
    • Edgar, D.M.1    Dement, W.C.2    Fuller, C.A.3
  • 10
    • 0015119210 scopus 로고
    • Clock mutants of Drosophila melanogaster
    • Konopka, R.J.; Benzer, S. Clock mutants of Drosophila melanogaster. Proc. Natl Acad Sci. USA 1971, 68(9), 2112-6.
    • (1971) Proc. Natl Acad Sci. USA , vol.68 , Issue.9 , pp. 2112-2116
    • Konopka, R.J.1    Benzer, S.2
  • 12
    • 0033847103 scopus 로고    scopus 로고
    • Targeted disruption of the mPer3 gene: Subtle effects on circadian clock function
    • Shearman, L.P.; Jin, X.W.; Lee, C.G.; Reppert, S.M.; Weaver, D.R.; Targeted disruption of the mPer3 gene: Subtle effects on circadian clock function. Mol. Cell. Biol. 2000, 20(17), 6269-75.
    • (2000) Mol. Cell. Biol , vol.20 , Issue.17 , pp. 6269-6275
    • Shearman, L.P.1    Jin, X.W.2    Lee, C.G.3    Reppert, S.M.4    Weaver, D.R.5
  • 13
    • 14644435678 scopus 로고    scopus 로고
    • The hypothalamic integrator for circadian rhythms
    • Saper, C.B.; Lu, J.; Chou, T.C.; Gooley, J. The hypothalamic integrator for circadian rhythms. Trends Neurosci. 2005, 28(3), 152-7.
    • (2005) Trends Neurosci , vol.28 , Issue.3 , pp. 152-157
    • Saper, C.B.1    Lu, J.2    Chou, T.C.3    Gooley, J.4
  • 15
    • 0027445242 scopus 로고
    • Thalamocortical oscillations in the sleeping and aroused brain
    • Steriade, M.; McCormick, D.A.; Sejnowski, T.J. Thalamocortical oscillations in the sleeping and aroused brain. Science 1993, 262(5134), 679-85.
    • (1993) Science , vol.262 , Issue.5134 , pp. 679-685
    • Steriade, M.1    McCormick, D.A.2    Sejnowski, T.J.3
  • 16
    • 14644408095 scopus 로고    scopus 로고
    • Genetics of normal and pathological sleep in humans
    • Dauviltiers, Y.; Maret S.; Tafti, M. Genetics of normal and pathological sleep in humans. Sleep Med. Rev. 2005, 9(2), 91-100.
    • (2005) Sleep Med. Rev , vol.9 , Issue.2 , pp. 91-100
    • Dauviltiers, Y.1    Maret, S.2    Tafti, M.3
  • 17
    • 1642436839 scopus 로고    scopus 로고
    • Hereditary Creutzfeldt-Jakob disease and fatal familial insomnia
    • Gambetti, P.; Parchi, P.; Chen, S.G. Hereditary Creutzfeldt-Jakob disease and fatal familial insomnia. Clin. Lab. Med. 2003, 23(1), 43-64.
    • (2003) Clin. Lab. Med , vol.23 , Issue.1 , pp. 43-64
    • Gambetti, P.1    Parchi, P.2    Chen, S.G.3
  • 18
    • 24144441743 scopus 로고    scopus 로고
    • Fatal familial insomnia: A model disease in sleep physiopathology
    • Montagna, P.; Fatal familial insomnia: A model disease in sleep physiopathology. Sleep Med. Rev. 2005, 9(5), 339-53.
    • (2005) Sleep Med. Rev , vol.9 , Issue.5 , pp. 339-353
    • Montagna, P.1
  • 19
    • 0020503776 scopus 로고
    • Relationships in sleep characteristics of identical and fraternal twins
    • Webb, W.B.; Campbell, S.S. Relationships in sleep characteristics of identical and fraternal twins. Arch. Gen. Psychiatry 1983, 40(10), 1093-5.
    • (1983) Arch. Gen. Psychiatry , vol.40 , Issue.10 , pp. 1093-1095
    • Webb, W.B.1    Campbell, S.S.2
  • 20
    • 0033529520 scopus 로고    scopus 로고
    • The sleep disorder canine narcolepsy is caused by a mutation in the hypocretin (orexin) receptor2 gene
    • Lin, L.; Faraco, J.; Li, R.; Kadotani, H.; Rogers, W.; Lin, X.; Qiu, X.; de Jong, P.J.; Nishino, S.; Mignot E. The sleep disorder canine narcolepsy is caused by a mutation in the hypocretin (orexin) receptor2 gene. Cell 1999, 698(3), 365-76.
    • (1999) Cell , vol.698 , Issue.3 , pp. 365-376
    • Lin, L.1    Faraco, J.2    Li, R.3    Kadotani, H.4    Rogers, W.5    Lin, X.6    Qiu, X.7    de Jong, P.J.8    Nishino, S.9    Mignot, E.10
  • 22
    • 0033971611 scopus 로고    scopus 로고
    • Hypocretin (orexin) deficiency in human mrcolepsy
    • Nishino, S.; Ripley, B.; Overeem, S.; Lammers, G.J.; Mignot, E. Hypocretin (orexin) deficiency in human mrcolepsy. Lancet 2000, 355(9197), 39-40.
    • (2000) Lancet , vol.355 , Issue.9197 , pp. 39-40
    • Nishino, S.1    Ripley, B.2    Overeem, S.3    Lammers, G.J.4    Mignot, E.5
  • 25
    • 0020331686 scopus 로고
    • Prostaglandin- D2 Induces Sleep When Micro-Injected Into the Preoptic Area of Conscious Rats
    • Ueno, R.; Ishikawa, Y.; Nakayama, T.; Hayaishi, O. Prostaglandin- D2 Induces Sleep When Micro-Injected Into the Preoptic Area of Conscious Rats. Biochem. Biophys. Res. Commun. 1982, 109(2), 576-82.
    • (1982) Biochem. Biophys. Res. Commun , vol.109 , Issue.2 , pp. 576-582
    • Ueno, R.1    Ishikawa, Y.2    Nakayama, T.3    Hayaishi, O.4
  • 26
    • 33846931612 scopus 로고    scopus 로고
    • Prostaglandins and adenosine in the regulation of sleep and wakefulness
    • Huang, Z.L.; Urade, Y.; Hayaish, O. Prostaglandins and adenosine in the regulation of sleep and wakefulness. Curr. Opin. Pharmacol. 2007, 7(1), 33-8.
    • (2007) Curr. Opin. Pharmacol , vol.7 , Issue.1 , pp. 33-38
    • Huang, Z.L.1    Urade, Y.2    Hayaish, O.3
  • 30
    • 0033546155 scopus 로고    scopus 로고
    • Metabolic deficiencies in alcohol dehydrogenase Adh1, Adh3, and Adh4 null mutant mice. Overlapping roles of Adh1 and Adh4 in ethanol clearance and metabolism of retinol to retmoic acid
    • Deltour, L.; Foglio, M.H.; Duester, G. Metabolic deficiencies in alcohol dehydrogenase Adh1, Adh3, and Adh4 null mutant mice. Overlapping roles of Adh1 and Adh4 in ethanol clearance and metabolism of retinol to retmoic acid. J. Biol. Chem. 1999, 274(24), 16796-801.
    • (1999) J. Biol. Chem , vol.274 , Issue.24 , pp. 16796-16801
    • Deltour, L.1    Foglio, M.H.2    Duester, G.3
  • 31
    • 0034484828 scopus 로고    scopus 로고
    • Altered behavior and alcohol tolerance in transgenic mice lacking MAO A: A comparison with effects of MAO A inhibitor clorgyline
    • Popova, N.K.; Vishnivetskaya, G.B.; Ivanova, E.A.; Skrinskaya, J.A.; Seif, I. Altered behavior and alcohol tolerance in transgenic mice lacking MAO A: A comparison with effects of MAO A inhibitor clorgyline. Pharmacol. Biochem. Behav. 2000, 67(4), 719-27.
    • (2000) Pharmacol. Biochem. Behav , vol.67 , Issue.4 , pp. 719-727
    • Popova, N.K.1    Vishnivetskaya, G.B.2    Ivanova, E.A.3    Skrinskaya, J.A.4    Seif, I.5
  • 37
    • 35548953757 scopus 로고    scopus 로고
    • CB1 receptors: Emerging evidence for central and peripheral mechanisms that regulate energy balance, metabolism, and cardiovascular health
    • Cota, D. CB1 receptors: Emerging evidence for central and peripheral mechanisms that regulate energy balance, metabolism, and cardiovascular health. Diabetes Metab. Res. Rev. 2007, 23(7), 507-17.
    • (2007) Diabetes Metab. Res. Rev , vol.23 , Issue.7 , pp. 507-517
    • Cota, D.1
  • 38
    • 0037123684 scopus 로고    scopus 로고
    • Intensification of the development of ethanol dependence in mice lacking doparnine D(3) receptor
    • Narita, M.; Soma, M.; Tamaki, H.; Narita, M.; Suzuki, T. Intensification of the development of ethanol dependence in mice lacking doparnine D(3) receptor. Neurosci. Lett. 2002, 324(2), 129-32.
    • (2002) Neurosci. Lett , vol.324 , Issue.2 , pp. 129-132
    • Narita, M.1    Soma, M.2    Tamaki, H.3    Narita, M.4    Suzuki, T.5
  • 39
    • 33646586398 scopus 로고    scopus 로고
    • Signaling mediated by the dopamine D2 receptor potentiates circadian regulation by CLOCK:BMAL1
    • Yujnovsky, I.; Hirayama, J.; Doi, M.; Borrelli, E.; Sassone-Corsi, P. Signaling mediated by the dopamine D2 receptor potentiates circadian regulation by CLOCK:BMAL1. Proc. Natl. Acad. Sci. USA 2006; 103(16), 6386-91.
    • (2006) Proc. Natl. Acad. Sci. USA , vol.103 , Issue.16 , pp. 6386-6391
    • Yujnovsky, I.1    Hirayama, J.2    Doi, M.3    Borrelli, E.4    Sassone-Corsi, P.5
  • 40
    • 0037207457 scopus 로고    scopus 로고
    • Deletion of the alphal or beta2 subunit of GABAA receptors reduces actions of alcohol and other drugs
    • Blednov, Y.A.; Jung, S.; Alva, H.; Wallace, D.; Rosahl, T.; Whiting, P.J.; Harris, R.A. Deletion of the alphal or beta2 subunit of GABAA receptors reduces actions of alcohol and other drugs. J. Pharmacol. Exp. Ther. 2003, 304(1), 30-6.
    • (2003) J. Pharmacol. Exp. Ther , vol.304 , Issue.1 , pp. 30-36
    • Blednov, Y.A.1    Jung, S.2    Alva, H.3    Wallace, D.4    Rosahl, T.5    Whiting, P.J.6    Harris, R.A.7
  • 42
    • 33645229309 scopus 로고    scopus 로고
    • Altered sleep-wake characteristics and lack of arousal response to H3 receptor antagonist in histamine H1 receptor knockout mice
    • Huang, Z.L.; Mochizuki, T.; Qu, W.M.; Hong, Z.Y.; Watanabe, T.; Urade, Y.; Hayaishi, O. Altered sleep-wake characteristics and lack of arousal response to H3 receptor antagonist in histamine H1 receptor knockout mice. Proc. Natl. Acad Sci. USA 2006, 103(12), 4687-92.
    • (2006) Proc. Natl. Acad Sci. USA , vol.103 , Issue.12 , pp. 4687-4692
    • Huang, Z.L.1    Mochizuki, T.2    Qu, W.M.3    Hong, Z.Y.4    Watanabe, T.5    Urade, Y.6    Hayaishi, O.7
  • 45
    • 0037073892 scopus 로고    scopus 로고
    • Panda, S.; Sato, T.K.; Castrucci, A.M.; Rollag, M.D.; DeGrip, W.J.; Hogenesch, J.B.; Provencio, I.; Kay, S.A. Melanopsin (Opn4) requirement for normal light-induced circadian phase shifting. Science 2002, 298(5601), 2213-6.
    • Panda, S.; Sato, T.K.; Castrucci, A.M.; Rollag, M.D.; DeGrip, W.J.; Hogenesch, J.B.; Provencio, I.; Kay, S.A. Melanopsin (Opn4) requirement for normal light-induced circadian phase shifting. Science 2002, 298(5601), 2213-6.
  • 49
    • 33645108005 scopus 로고    scopus 로고
    • Kv3 potassium channels control the duration of dfferent arousal states by distinct stochastic and clock-like mechanisms
    • Joho, R.H.; Marks, G.A.; Espinosa, F. Kv3 potassium channels control the duration of dfferent arousal states by distinct stochastic and clock-like mechanisms. Eur. J. Neurosci. 2006, 23(6), 1567-74.
    • (2006) Eur. J. Neurosci , vol.23 , Issue.6 , pp. 1567-1574
    • Joho, R.H.1    Marks, G.A.2    Espinosa, F.3
  • 51
    • 0042626226 scopus 로고    scopus 로고
    • BMAL1-dependent circadian oscillation of nuclear CLOCK: Posttranslational events induced by dimerization of transcriptional activators of the mammalian clock system
    • Kondratov, R.V.; Chernov, M.V.; Kondratova, A.A.; Gorbacheva, V.Y.; Gudkov, A.V.; Antoch, M.P. BMAL1-dependent circadian oscillation of nuclear CLOCK: Posttranslational events induced by dimerization of transcriptional activators of the mammalian clock system. Genes Dev. 2003, 17(15), 1921-32.
    • (2003) Genes Dev , vol.17 , Issue.15 , pp. 1921-1932
    • Kondratov, R.V.1    Chernov, M.V.2    Kondratova, A.A.3    Gorbacheva, V.Y.4    Gudkov, A.V.5    Antoch, M.P.6
  • 55
    • 0033598780 scopus 로고    scopus 로고
    • Altered emotional and locomotor responses in mice deficient in the transcription factor CREM
    • Maldonado, R.; Smadja, C.; Mazzucchelli, C.; Sassone-Corsi, P. Altered emotional and locomotor responses in mice deficient in the transcription factor CREM. Proc. Natl. Acad. Sci. USA 1999, 96(24), 14094-9.
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , Issue.24 , pp. 14094-14099
    • Maldonado, R.1    Smadja, C.2    Mazzucchelli, C.3    Sassone-Corsi, P.4
  • 57
    • 0034651090 scopus 로고    scopus 로고
    • The transcription factor DBP affects circadian sleep consolidation and rhythmic EEG activity
    • Franken, P.; Lopez-Molina, L.; Marcacci, L.; Schibler, U.; Tafti, M. The transcription factor DBP affects circadian sleep consolidation and rhythmic EEG activity. J Neurosci. 2000, 20(2), 617-25.
    • (2000) J Neurosci , vol.20 , Issue.2 , pp. 617-625
    • Franken, P.1    Lopez-Molina, L.2    Marcacci, L.3    Schibler, U.4    Tafti, M.5
  • 58
    • 0036895745 scopus 로고    scopus 로고
    • Loss of photic entrainment and altered free-running circadian rhythms in math5-/- mice
    • Wee, R.; Castrucci, A.M.; Provencio, I.; Gan, L.; Van Gelder, R.N. Loss of photic entrainment and altered free-running circadian rhythms in math5-/- mice. J. Neurosci. 2002, 22(23), 10427-33.
    • (2002) J. Neurosci , vol.22 , Issue.23 , pp. 10427-10433
    • Wee, R.1    Castrucci, A.M.2    Provencio, I.3    Gan, L.4    Van Gelder, R.N.5
  • 61
    • 0034989269 scopus 로고    scopus 로고
    • Differential functions of mPer1, mPer2, and mPer3 in the SCN circadian clock
    • Bae, K.; Jin, X.; Maywood, E.S.; Hastings, M.H.; Reppert, S.M.; Weaver, D.R. Differential functions of mPer1, mPer2, and mPer3 in the SCN circadian clock. Neuron 2001, 30(2), 525-36.
    • (2001) Neuron , vol.30 , Issue.2 , pp. 525-536
    • Bae, K.1    Jin, X.2    Maywood, E.S.3    Hastings, M.H.4    Reppert, S.M.5    Weaver, D.R.6
  • 63
    • 0021677452 scopus 로고
    • Differential Sleep-Promoting Effects of 5 Sleep Substances Nocturnally Infused in Unrestrained Rats
    • Inoue, S.; Honda, K.; Komoda, Y.; Uchizono, K.; Ueno, R.; Hayaishi, O. Differential Sleep-Promoting Effects of 5 Sleep Substances Nocturnally Infused in Unrestrained Rats. Proc. Natl. Acad. Sci. USA Biol. Sci. 1984, 81(19), 6240-4.
    • (1984) Proc. Natl. Acad. Sci. USA Biol. Sci , vol.81 , Issue.19 , pp. 6240-6244
    • Inoue, S.1    Honda, K.2    Komoda, Y.3    Uchizono, K.4    Ueno, R.5    Hayaishi, O.6
  • 66
    • 2342474973 scopus 로고    scopus 로고
    • Genes for prostaglandin D synthase and receptor as well as adenosine A(2A) receptor are involved in the homeostatic regulation of NREM sleep
    • Hayaishi, O.; Urade, Y.; Eguchi, N.; Huang, Z.L. Genes for prostaglandin D synthase and receptor as well as adenosine A(2A) receptor are involved in the homeostatic regulation of NREM sleep. Arch. Italiennes de Biol. 2004, 142(4), 533-9.
    • (2004) Arch. Italiennes de Biol , vol.142 , Issue.4 , pp. 533-539
    • Hayaishi, O.1    Urade, Y.2    Eguchi, N.3    Huang, Z.L.4
  • 67
    • 34250796764 scopus 로고    scopus 로고
    • Barcelo, A.; de la Pena, M.; Barbe, F.; Pierola, J.; Bosch, M.; Agusti, A.G.N. Prostaglandin D synthase (beta trace) levels in sleep apnea patients with and without sleepiness. Sleep Med. 2007, 8(5), 509-11.
    • Barcelo, A.; de la Pena, M.; Barbe, F.; Pierola, J.; Bosch, M.; Agusti, A.G.N. Prostaglandin D synthase (beta trace) levels in sleep apnea patients with and without sleepiness. Sleep Med. 2007, 8(5), 509-11.
  • 68
    • 0025696564 scopus 로고
    • The somnogenic T lymphocyte suppressor prostaglandin D2 is selectively elevated in cerebrospinal fluid of advanced sleeping sickness patients
    • Pentreath, V.W.; Rees, K.; Owolabi, O.A.; Philip, K.A.; Dona, F. The somnogenic T lymphocyte suppressor prostaglandin D2 is selectively elevated in cerebrospinal fluid of advanced sleeping sickness patients. Trans. Royal Soc. Trop. Med. Hygiene 1990, 84, 795-9.
    • (1990) Trans. Royal Soc. Trop. Med. Hygiene , vol.84 , pp. 795-799
    • Pentreath, V.W.1    Rees, K.2    Owolabi, O.A.3    Philip, K.A.4    Dona, F.5
  • 69
    • 0004452705 scopus 로고    scopus 로고
    • Circadian Disorders of the Sleep-Wake Cycle
    • Kryger MH, Roth T, Dement WC, editors, 3rd ed. Philadelphia: W.B. Saunders Company;
    • Baker, S.K.; Zee, P.C. Circadian Disorders of the Sleep-Wake Cycle. In: Kryger MH, Roth T, Dement WC, editors. Principles and Practice of Sleep Medicine. 3rd ed. Philadelphia: W.B. Saunders Company; 2000. p. 606-14.
    • (2000) Principles and Practice of Sleep Medicine , pp. 606-614
    • Baker, S.K.1    Zee, P.C.2
  • 70
    • 0141743929 scopus 로고    scopus 로고
    • A length polymrphism in the circadian clock gene Per3 is linked to delayed sleep phase syndrome and extreme diurnal preference
    • Archer, S.N.; Robillard, D.L.; Skene, D.J.; Smits, M.; Williams, A.; Arendt, J.; von Schantz, M. A length polymrphism in the circadian clock gene Per3 is linked to delayed sleep phase syndrome and extreme diurnal preference. Sleep 2003, 26, A109.
    • (2003) Sleep , vol.26
    • Archer, S.N.1    Robillard, D.L.2    Skene, D.J.3    Smits, M.4    Williams, A.5    Arendt, J.6    von Schantz, M.7
  • 71
    • 48249094712 scopus 로고    scopus 로고
    • PER3 polymorphism predictsusceptibility to sleep deprivation-induced impairment of early morning executive performance
    • Groeger, J.; Lo, J.; Viola, A.; von Schantz, M.; Archer, S.; Dijk, D. PER3 polymorphism predictsusceptibility to sleep deprivation-induced impairment of early morning executive performance. Sleep 2007, 30, A54.
    • (2007) Sleep , vol.30
    • Groeger, J.1    Lo, J.2    Viola, A.3    von Schantz, M.4    Archer, S.5    Dijk, D.6
  • 74
    • 48249114487 scopus 로고    scopus 로고
    • Age-related change in the association between a variable number tandem repeat polymorphism in the (PER3) gene and preferred timing of sleep and waking activities
    • Jones, K.H.; Ellis, J.; von Schantz, M.; Skene, D.J.; Dijk, D.; Archer, S.N. Age-related change in the association between a variable number tandem repeat polymorphism in the (PER3) gene and preferred timing of sleep and waking activities. J. Sleep Res. 2006, 15, 97-8.
    • (2006) J. Sleep Res , vol.15 , pp. 97-98
    • Jones, K.H.1    Ellis, J.2    von Schantz, M.3    Skene, D.J.4    Dijk, D.5    Archer, S.N.6
  • 75
    • 0037686260 scopus 로고    scopus 로고
    • Genetics and Molecular Biology of Rhythms in Drosophila and Other Insects
    • Hall JC. Genetics and Molecular Biology of Rhythms in Drosophila and Other Insects. Advances in genetics 2003;48:1-280.
    • (2003) Advances in genetics , vol.48 , pp. 1-280
    • Hall, J.C.1
  • 76
    • 0344642958 scopus 로고    scopus 로고
    • Expression of mCLOCK and Other Circadian Clock-Relevant Proteins in the Mouse Suprachiasmatic Nuclei
    • Maywood, E.S.; O'Brien, J.A.; Hastings, M.H. Expression of mCLOCK and Other Circadian Clock-Relevant Proteins in the Mouse Suprachiasmatic Nuclei. J. Neuroendocrinol. 2003, 15(4), 329-34.
    • (2003) J. Neuroendocrinol , vol.15 , Issue.4 , pp. 329-334
    • Maywood, E.S.1    O'Brien, J.A.2    Hastings, M.H.3
  • 77
    • 33947319818 scopus 로고    scopus 로고
    • AMPA receptor potentiators as cognitive enhancers
    • O'Neill, M.J.; Dix, S. AMPA receptor potentiators as cognitive enhancers. Idrugs 2007, 10(3), 185-92.
    • (2007) Idrugs , vol.10 , Issue.3 , pp. 185-192
    • O'Neill, M.J.1    Dix, S.2
  • 78
    • 48249139949 scopus 로고    scopus 로고
    • Is translational research monkey business: The journey of a novel AMPAKINE (CX 717) from primate to a human phase 1B study with a cognitive impairment model
    • Tollefson, G.; Mansbach, H.; Deadwyler, S. Is translational research monkey business: The journey of a novel AMPAKINE (CX 717) from primate to a human phase 1B study with a cognitive impairment model. Neuropsychopharmacology 2005, 30, S83-S84.
    • (2005) Neuropsychopharmacology , vol.30
    • Tollefson, G.1    Mansbach, H.2    Deadwyler, S.3
  • 79
    • 33845268266 scopus 로고    scopus 로고
    • Insufficient sleep reversibly alters bidirectional synaptic plasticity and NMDA receptor function
    • Kopp, C.; Longordo, F.; Nicholson, J.R.; Luthi, A. Insufficient sleep reversibly alters bidirectional synaptic plasticity and NMDA receptor function. J. Neurosci. 2006, 26(48), 12456-65.
    • (2006) J. Neurosci , vol.26 , Issue.48 , pp. 12456-12465
    • Kopp, C.1    Longordo, F.2    Nicholson, J.R.3    Luthi, A.4
  • 80
    • 0029670123 scopus 로고    scopus 로고
    • Which GABA(A)-receptor subtypes really occur in the brain?
    • McKernan, R.M.; Whiting, P.J. Which GABA(A)-receptor subtypes really occur in the brain? Trends Neurosci. 1996, 19(4), 139-43.
    • (1996) Trends Neurosci , vol.19 , Issue.4 , pp. 139-143
    • McKernan, R.M.1    Whiting, P.J.2
  • 81
    • 0031799363 scopus 로고    scopus 로고
    • International Union of Pharmacology. XV. Subtypes of gamma-aminobutyric acid(A) receptors: Classification on the basis of subunit structure and receptor function
    • Barnard, E.A.; Skolnick, P.; Olsen, R.W.; Mohler, H.; Sieghart, W.; Biggio, G.; Braestrup, C.; Bateson, A.N.; Langer, S.Z. International Union of Pharmacology. XV. Subtypes of gamma-aminobutyric acid(A) receptors: Classification on the basis of subunit structure and receptor function. Pharmacol. Rev. 1998, 50(2), 291-313.
    • (1998) Pharmacol. Rev , vol.50 , Issue.2 , pp. 291-313
    • Barnard, E.A.1    Skolnick, P.2    Olsen, R.W.3    Mohler, H.4    Sieghart, W.5    Biggio, G.6    Braestrup, C.7    Bateson, A.N.8    Langer, S.Z.9
  • 83
    • 70449548389 scopus 로고
    • Effect of lesions of the pontile reticular formation on sleep in the cat]
    • Jouvet M.; MOUNIER D. [Effect of lesions of the pontile reticular formation on sleep in the cat]. C R Seances Soc. Biol Fil. 1960, 154, 2301-5.
    • (1960) C R Seances Soc. Biol Fil , vol.154 , pp. 2301-2305
    • Jouvet, M.1    MOUNIER, D.2
  • 84
    • 0028198059 scopus 로고
    • Hypothalarno-Preoptic Histaminergic Projections in Sleep-Wake Control in the Cat
    • Lin, J.S.; Sakai, K.; Jouvet, M. Hypothalarno-Preoptic Histaminergic Projections in Sleep-Wake Control in the Cat. Eur. J. Neurosci. 1994, 6(4), 618-25.
    • (1994) Eur. J. Neurosci , vol.6 , Issue.4 , pp. 618-625
    • Lin, J.S.1    Sakai, K.2    Jouvet, M.3
  • 86
    • 0026659695 scopus 로고
    • Neurobiological structure of the revised limit cycle reciprocal interaction model of REM cycle control
    • McCarley, R.W.; Massaquoi, S.G. Neurobiological structure of the revised limit cycle reciprocal interaction model of REM cycle control. J. Sleep Res. 1992, 1(2), 132-7.
    • (1992) J. Sleep Res , vol.1 , Issue.2 , pp. 132-137
    • McCarley, R.W.1    Massaquoi, S.G.2
  • 87
    • 0027325747 scopus 로고
    • Mechanisms of Oscillatory Activity in Guinea-Pig Nucleus-Reticularis Thalami In-Vitro - A Mammalian Pacemaker
    • Bal, T.; Mccormick, D.A. Mechanisms of Oscillatory Activity in Guinea-Pig Nucleus-Reticularis Thalami In-Vitro - A Mammalian Pacemaker. J. Physiol. London 1993, 468, 669-91.
    • (1993) J. Physiol. London , vol.468 , pp. 669-691
    • Bal, T.1    Mccormick, D.A.2
  • 88
    • 0026003378 scopus 로고
    • Serotonin and Noradrenaline Excite Gabaergic Neurons of the Guinea-Pig and Cat Nucleus Reticularis Thalami
    • Mccormick, D.A.; Wang, Z. Serotonin and Noradrenaline Excite Gabaergic Neurons of the Guinea-Pig and Cat Nucleus Reticularis Thalami. J. Physiol.-London 1991, 442, 235-55.
    • (1991) J. Physiol.-London , vol.442 , pp. 235-255
    • Mccormick, D.A.1    Wang, Z.2
  • 89
    • 0025753001 scopus 로고
    • Paradoxical Sleep and Its Chemical Structural Substrates in the Brain
    • Jones, B.E. Paradoxical Sleep and Its Chemical Structural Substrates in the Brain. Neuroscience 1991, 40(3), 637-56.
    • (1991) Neuroscience , vol.40 , Issue.3 , pp. 637-656
    • Jones, B.E.1
  • 90
    • 1542568317 scopus 로고    scopus 로고
    • Arousal systems
    • 438-S451
    • Jones, B.E. Arousal systems. Front. Biosci. 2003, 8, 438-S451.
    • (2003) Front. Biosci , vol.8
    • Jones, B.E.1
  • 91
    • 0026587198 scopus 로고
    • Cellular Mechanisms Underlying Cholinergic and Noradrenergic Modulation of Neuronal Firing Mode in the Cat and Guinea-Pig Dorsal Lateral Geruculate-Nucleus
    • Mccormick, D.A. Cellular Mechanisms Underlying Cholinergic and Noradrenergic Modulation of Neuronal Firing Mode in the Cat and Guinea-Pig Dorsal Lateral Geruculate-Nucleus. J. Neurosci. 1992, 12(1), 278-89.
    • (1992) J. Neurosci , vol.12 , Issue.1 , pp. 278-289
    • Mccormick, D.A.1
  • 92
    • 0025723466 scopus 로고
    • Actions of Norepinephrine in the Cerebral-Cortex and Thalamus - Implications for Function of the Central Noradrenergic System
    • Mccormick, D.A.; Pape, H.C.; Williamson, A. Actions of Norepinephrine in the Cerebral-Cortex and Thalamus - Implications for Function of the Central Noradrenergic System. Prog. Brain Res. 1991, 88, 293-305.
    • (1991) Prog. Brain Res , vol.88 , pp. 293-305
    • Mccormick, D.A.1    Pape, H.C.2    Williamson, A.3
  • 95
    • 16544367049 scopus 로고    scopus 로고
    • Pharmacologic management of insomnia
    • Walsh, J.K. Pharmacologic management of insomnia. J. Clin. Psychiatry 2004, 65(Suppl 16), 41-5.
    • (2004) J. Clin. Psychiatry , vol.65 , Issue.SUPPL. 16 , pp. 41-45
    • Walsh, J.K.1
  • 96
    • 4444323559 scopus 로고    scopus 로고
    • Hypnotic' prescription patterns in a large managed-care population
    • Roehrs, T.; Roth, T. 'Hypnotic' prescription patterns in a large managed-care population. Sleep Med. 2004, 5(5), 463-6.
    • (2004) Sleep Med , vol.5 , Issue.5 , pp. 463-466
    • Roehrs, T.1    Roth, T.2
  • 98
    • 17444420295 scopus 로고    scopus 로고
    • Benefit-risk assessment of zaleplon in the treatment of insomnia
    • Barbera, J.; Shaprio, C. Benefit-risk assessment of zaleplon in the treatment of insomnia. Drug Safety 2005, 28(4), 301-18.
    • (2005) Drug Safety , vol.28 , Issue.4 , pp. 301-318
    • Barbera, J.1    Shaprio, C.2
  • 99
    • 0019460842 scopus 로고
    • Spontaneous and Melatonin-Induced Testicular Regression in Male Golden-Hamsters - Augmented Sensitivity of the Old Male to Melatonin Inhibition
    • Chen, H.J. Spontaneous and Melatonin-Induced Testicular Regression in Male Golden-Hamsters - Augmented Sensitivity of the Old Male to Melatonin Inhibition. Neuroendocrinology 1981, 33(l), 43-6.
    • (1981) Neuroendocrinology , vol.33 , Issue.L , pp. 43-46
    • Chen, H.J.1
  • 100
    • 0142229958 scopus 로고    scopus 로고
    • Clock genes in calendar cells as the basis of annual timekeeping in mammals - a unifying hypothesis
    • Lincoln, G.A.; Andersson, H Loudon A. Clock genes in calendar cells as the basis of annual timekeeping in mammals - a unifying hypothesis. J. Endocrinol. 2003, 179(1), 1-13.
    • (2003) J. Endocrinol , vol.179 , Issue.1 , pp. 1-13
    • Lincoln, G.A.1    Andersson, H.2    Loudon, A.3
  • 101
    • 0030778136 scopus 로고    scopus 로고
    • Sleeppromoting effects of melatonin: At what dose, in whom, under what conditions, and by what mechanisms?
    • Sack, R.L.; Hughes, R.J.; Edgar, D.M.; Lewy, A.J. Sleeppromoting effects of melatonin: At what dose, in whom, under what conditions, and by what mechanisms? Sleep 1997, 20(10), 908-15.
    • (1997) Sleep , vol.20 , Issue.10 , pp. 908-915
    • Sack, R.L.1    Hughes, R.J.2    Edgar, D.M.3    Lewy, A.J.4
  • 102
    • 29844447353 scopus 로고    scopus 로고
    • An efficacy, safety, and dose-response study of Ramelteon in patients with chronic primary insomnia
    • Erman, M.; Seiden, D.; Zammit, G.; Sainati, S.; Zhang, J. An efficacy, safety, and dose-response study of Ramelteon in patients with chronic primary insomnia. Sleep Med. 2006, 7(l), 17-24.
    • (2006) Sleep Med , vol.7 , Issue.L , pp. 17-24
    • Erman, M.1    Seiden, D.2    Zammit, G.3    Sainati, S.4    Zhang, J.5
  • 103
    • 33646925615 scopus 로고    scopus 로고
    • Effects of ramelteon on patient-reported sleep latency in older adults with chronic insomnia
    • Roth, T.; Seiden, D.; Sainati, S.; Wang-Weigand, S.; Zhang, J.; Zee, P. Effects of ramelteon on patient-reported sleep latency in older adults with chronic insomnia. Sleep Med. 2006, 7(4), 312-8.
    • (2006) Sleep Med , vol.7 , Issue.4 , pp. 312-318
    • Roth, T.1    Seiden, D.2    Sainati, S.3    Wang-Weigand, S.4    Zhang, J.5    Zee, P.6
  • 104
    • 18044381335 scopus 로고    scopus 로고
    • Dopaminergic-adrenergic interactions in the wake promoting mechanism of modafinil
    • Wisor, J.P.; Eriksson, K.S. Dopaminergic-adrenergic interactions in the wake promoting mechanism of modafinil. Neuroscience 2005, 132(4), 1027-34.
    • (2005) Neuroscience , vol.132 , Issue.4 , pp. 1027-1034
    • Wisor, J.P.1    Eriksson, K.S.2
  • 105
    • 0025609959 scopus 로고
    • The Effects of Gamma-Hydroxybutyrate on the Sleep of Narcolepsy Patients - A Double-Blind-Study
    • Scrima, L.; Hartman, P.G.; Johnson, F.H.; Thomas, E.E.; Hiller, F.C. The Effects of Gamma-Hydroxybutyrate on the Sleep of Narcolepsy Patients - A Double-Blind-Study. Sleep 1990 13(6), 479-90.
    • (1990) Sleep , vol.13 , Issue.6 , pp. 479-490
    • Scrima, L.1    Hartman, P.G.2    Johnson, F.H.3    Thomas, E.E.4    Hiller, F.C.5
  • 108
    • 34447519030 scopus 로고    scopus 로고
    • Histamine H-3 receptor ligands break ground in a remarkable plethora of therapeutic areas
    • Wijtmans, M.; Leurs, R.; de Esch, I. Histamine H-3 receptor ligands break ground in a remarkable plethora of therapeutic areas. Expert Opin. Invest. Drugs 2007, 16(7)967-85.
    • (2007) Expert Opin. Invest. Drugs , vol.16 , Issue.7 , pp. 967-985
    • Wijtmans, M.1    Leurs, R.2    de Esch, I.3


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