Cellular energetic status supervises the synthesis of bis-diphosphoinositol tetrakisphosphate independently of AMP-activated protein kinase

Molecular Pharmacology

Volumn 74, Issue 2, 2008, Pages 527-536

  Choi, Kuicheon ^a,b   Mollapour, Elahe ^a   Choi, Jae H ^a   Shears, Stephen B ^a  

^a NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

^b UNIVERSITY OF TEXAS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 2 (2 CHLORO 4 IODOANILINO) N CYCLOPROPYLMETHOXY 3,4 DIFLUOROBENZAMIDE; BIS DIPHOSPHOINOSITOL TETRAKISPHOSPHATE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHOPROTEIN; SMALL INTERFERING RNA;

ANIMAL CELL; ARTICLE; CELL ENERGY; CONTROLLED STUDY; EMBRYO; ENZYME ACTIVITY; HUMAN; HUMAN CELL; HYPEROSMOTIC STRESS; NONHUMAN; PRIORITY JOURNAL; PROTEIN SYNTHESIS;

ANIMALS; CELLS, CULTURED; ENERGY METABOLISM; HUMANS; INOSITOL PHOSPHATES; MALE; MAP KINASE SIGNALING SYSTEM; MULTIENZYME COMPLEXES; MYOCYTES, SMOOTH MUSCLE; PROTEIN KINASE INHIBITORS; PROTEIN-SERINE-THREONINE KINASES; RATS;

EID: 47949131441     PISSN: 0026895X     EISSN: 15210111     Source Type: Journal    
DOI: 10.1124/mol.107.044628     Document Type: Article

References (37)

1. Al-Hakim AK, Goransson O, Deak M, Toth R, Campbell DG, Morrice NA, Prescott AR, and Alessi DR (2005) 14-3-3 cooperates with LKB1 to regulate the activity and localization of QSK and SIK. J Cell Sci 118:5661- 5673.
2. Ali N, Duden R, Bembenek ME, and Shears SB (1995) The interaction of coatomer with inositol polyphosphates is conserved in Saccharomyces cerevisiae. Biochem J 310:279-284.
3. Bain J, Plater L, Elliott M, Shpiro N, Hastie J, McLauchlan H, Klevernic I, Arthur S, Alessi D, and Cohen P (2007) The selectivity of protein kinase inhibitors: a further update. Biochem J 408:297-315.
4. Belfield A and Goldberg DM (1969) Application of a continuous spectrophotometric assay for 5′nucleotidase activity in normal subjects and patients with liver and bone disease. Clin Chem 15:931-939.
5. Bennett M, Onnebo SM, Azevedo C, and Saiardi A (2006) Inositol pyrophosphates: metabolism and signaling. Cell Mol Life Sci 63:552-564.
6. Bhandari R, Saiardi A, Ahmadibeni Y, Snowman AM, Resnick AC, Kristiansen TZ, Molina H, Pandey A, Werner JK Jr, Juluri KR, et al. (2007) Protein pyrophosphorylation by inositol pyrophosphates is a posttranslational event. Proc Natl Acad Sci U S A 104:15305-15310.
7. Biemans-Oldehinkel E, Mahmood NA, and Poolman B (2006) A sensor for intracellular ionic strength. Proc Natl Acad Sci USA 103:10624- 10629.
8. Carling D, Clarke PR, Zammit V, and Hardie DG (1989) Purification and characterization of the AMP-activated protein kinase. Copurification of acetyl-CoA carboxylase kinase and 3-hydroxy-3-methylglutaryl-CoA reductase kinase activities. Eur J Biochem 186:129-136.
9. Choi JH, Williams J, Cho J, Falck JR, and Shears SB (2007) Purification, sequencing, and molecular identification of a mammalian PP-InsP5 kinase that is activated when cells are exposed to hyperosmotic stress. J Biol Chem 282:30763-30775.
10. 8 operates within highly restricted contexts. Cell Signal 17:1533-1541.
11. Daval M, Diot-Dupuy F, Bazin R, Hainault I, Viollet B, Vaulont S, Hajduch E, Ferre P, and Foufelle F (2005) Anti-lipolytic action of AMP-activated protein kinase in rodent adipocytes. J Biol Chem 280:25250-25257.
12. Dokladda K, Green KA, Pan DA, and Hardie DG (2005) PD98059 and U0126 activate AMP-activated protein kinase by increasing the cellular AMP:ATP ratio and not via inhibition of the MAP kinase pathway. FEBS Lett 579:236-240.
13. Epperson S, Gustafsson A, Gonzalez A, Villegas S, Meszaros J, and Brunton L (2005) Pharmacology of G-protein-linked signaling in cardiac fibroblasts, in Interstitial Fibrosis in Heart Failure pp 83-97, New York, Springer.
14. Fridy PC, Otto JC, and York JD (2007) Cloning and characterization of two human VIP1-like inositol hexakisphosphate and diphosphoinositol pentakisphosphate kinases. J Biol Chem 282:30754-30762.
15. Fryer LG, Parbu-Patel A, and Carling D (2002) The anti-diabetic drugs rosiglitazone and metformin stimulate AMP-activated protein kinase through distinct signaling pathways. J Biol Chem 277:25226-25232.
16. Hardie DG and Hawley SA (2001) AMP-activated protein kinase: the energy charge hypothesis revisited. Bioessays 23:1112-1119.
17. Henin N, Vincent MF, and Van den BG (1996) Stimulation ofrat liver AMP-activated protein kinase by AMP analogues. Biochim Biophys Acta 1290:197-203.
18. Inoki K, Zhu T, and Guan KL (2003) TSC2 mediates cellular energy response to control cell growth and survival. Cell 115:577-590.
19. Irvine RF and Schell M (2001) Back in the water: the return of the inositol phosphates. Nat Rev Mol Cell Biol 2:327-338.
20. Laussmann T, Reddy KM, Reddy KK, Falck JR, and Vogel G (1997) Diphopho-myo-inositol phosphates from Dictyostelium identified as D-6-diphospho-myo-inositol pentakisphosphate and D-5,6-bisdiphospho- myo-inositol tetrakisphosphate. Bio-chem J 322:31-33.
21. Lee YS, Mulugu S, York JD, and O'Shea EK (2007) Regulation of a cyclin-CDK-CDK inhibitor complex by inositol pyrophosphates. Science 316:109-112.
22. Luiken JJ, Coort SL, Willems J, Coumans WA, Bonen A, van der Vusse GJ, and Glatz JF (2003) Contraction-induced fatty acid translocase/CD36 translocation in rat cardiac myocytes is mediated through AMP-activated protein kinase signaling. Diabetes 52:1627-1634.
23. Luo HR, Huang YE, Chen JC, Sairardi A, Iijima M, Ye K, Huang Y, Nagata E, Devreotes P, and Snyder SH (2003) Inositol pyrophosphates mediate chemotaxis in Dictyostelium via pleckstrin homology domain-PtdIns(3,4,5)P3 interactions. Cell 114:559-572.
24. Marsin AS, Bertrand L, Rider MH, Deprez J, Beauloye C, Vincent MF, Van den BG, Carling D, and Hue L (2000) Phosphorylation and activation of heart PFK-2 by AMPK has a role in the stimulation of glycolysis during ischaemia. Curr Biol 10:1247-1255.
25. Menniti FS, Miller RN, Putney JW Jr, and Shears SB (1993) Turnover of inositol polyphosphate pyrophosphates in pancreatoma cells. J Biol Chem 268:3850-3856.
26. Merrill GF, Kurth EJ, Hardie DG, and Winder WW (1997) AICA riboside increases AMP-activated protein kinase, fatty acid oxidation, and glucose uptake in rat muscle. Am J Physiol 273:E1107-E1112.
27. Miyoshi N, Oubrahim H, Chock PB, and Stadtman ER (2006) Age-dependent cell death and the role of ATP in hydrogen peroxide-induced apoptosis and necrosis. Proc Natl Acad Sci U S A 103:1727-1731.
28. Nagata E, Luo HR, Saiardi A, Bae BI, Suzuki N, and Snyder SH (2005) Inositol hexakisphosphate kinase-2, a physiologic mediator of cell death. J Biol Chem 280:1634-1640.
29. Pesesse X, Choi K, Zhang T, and Shears SB (2004) Signalling by higher inositol polyphosphates: synthesis of bis-diphosphoinositol tetrakisphosphate ("InsP8") is selectively activated by hyperosmotic stress. J Biol Chem 279:43378-43381.
30. Safrany ST, Caffrey JJ, Yang X, Bembenek ME, Moyer MB, Burkhart WA, and Shears SB (1998) A novel context for the "MutT" module, a guardian of cell integrity, in a diphosphoinositol polyphosphate phosphohydrolase. EMBO J 17: 6599-6607.
31. 2- adrenergic receptors through a cAMP-mediated, A-kinase-independent mechanism. EMBO J 17:1710-1716.
32. Saiardi A, Bhandari A, Resnick R, Cain A, Snowman AM, and Snyder SH (2004) Inositol pyrophosphate: physiologic phosphorylation of proteins. Science 306: 2101-2105.
33. Sofer A, Lei K, Johannessen CM, and Ellisen LW (2005) Regulation of MTOR and cell growth in response to energy stress by REDD1. Mol Cell Biol 25:5834-5845.
34. Swinnen JV, Beckers A, Brusselmans K, Organe S, Segers J, Timmermans L, Vanderhoydonc F, Deboel L, Derua R, Waelkens E, et al. (2005) Mimicry of a cellular low energy status blocks tumor cell anabolism and suppresses the malignant phenotype. Cancer Res 65:2441-2448.
35. Yin W, Mu J, and Birnbaum MJ (2003) Role of AMP-activated protein kinase in cyclic AMP-dependent lipolysis In 3T3-L1 adipocytes. J Biol Chem 278:43074-43080.
36. Yung HW, Wyttenbach A, and Tolkovsky AM (2004) Aggravation of necrotic death of glucose-deprived cells by the MEK1 inhibitors U0126 and PD184161 through depletion of ATP. Biochem Pharmacol 68:351-360.
37. Zakaria M and Brown PR (1981) High-performance liquid chromatography of nucleotides, nucleosides and bases. J Chromatogr 226:267-290.