-
1
-
-
84990553409
-
Cytostatic and cytotoxic effects of Pannon (P-30 Protein), a novel anticancer agent
-
Darzynkiewicz Z, Carter SP, Mikulski SM, Ardelt WJ, Shogen K. Cytostatic and cytotoxic effects of Pannon (P-30 Protein), a novel anticancer agent. Cell Tissue Kinetics 1988; 21:169-82.
-
(1988)
Cell Tissue Kinetics
, vol.21
, pp. 169-182
-
-
Darzynkiewicz, Z.1
Carter, S.P.2
Mikulski, S.M.3
Ardelt, W.J.4
Shogen, K.5
-
2
-
-
0025960523
-
Amino acid sequence of an anti-tumor protein from Rana pipiens oocytes and early embryos. Homology to pancreatic ribonuclease
-
Ardelt W, Mikulski SM, Shogen K. Amino acid sequence of an anti-tumor protein from Rana pipiens oocytes and early embryos. Homology to pancreatic ribonuclease. J Biol Chem 1991; 266:245-51.
-
(1991)
J Biol Chem
, vol.266
, pp. 245-251
-
-
Ardelt, W.1
Mikulski, S.M.2
Shogen, K.3
-
3
-
-
0000512084
-
Enzymatic characterization of onconase, a novel ribonuclease with anti-tumor activity
-
Ardelt W, Lee HS, Randolph G, Viera A, Mikulski SM, Shogen K. Enzymatic characterization of onconase, a novel ribonuclease with anti-tumor activity. Protein Sci 1994; 3:137-47.
-
(1994)
Protein Sci
, vol.3
, pp. 137-147
-
-
Ardelt, W.1
Lee, H.S.2
Randolph, G.3
Viera, A.4
Mikulski, S.M.5
Shogen, K.6
-
4
-
-
0028266432
-
Refined 1.7Å X-ray crystallographic structure of P-30 protein, an amphibian ribonuclease with antitumor activity
-
Mosimann SC, Ardelt W, James MNG. Refined 1.7Å X-ray crystallographic structure of P-30 protein, an amphibian ribonuclease with antitumor activity. J Mol Biol 1994; 236:1141-53.
-
(1994)
J Mol Biol
, vol.236
, pp. 1141-1153
-
-
Mosimann, S.C.1
Ardelt, W.2
James, M.N.G.3
-
5
-
-
47749087053
-
Onconase and amphinase, the anti-tumor ribonucleases from Rana pipiens oocytes
-
in press
-
Ardelt W, Shogen K, Darzynkiewicz Z. Onconase and amphinase, the anti-tumor ribonucleases from Rana pipiens oocytes. Curr Pharm Biotechnol 2008; (in press).
-
(2008)
Curr Pharm Biotechnol
-
-
Ardelt, W.1
Shogen, K.2
Darzynkiewicz, Z.3
-
6
-
-
33748536073
-
Natural and engineered ribonucleases as potential cancer therapeutics
-
Arnold U, Ulbrich-Hofmann R. Natural and engineered ribonucleases as potential cancer therapeutics. Biotechnol Lett 2006; 28:1615-22.
-
(2006)
Biotechnol Lett
, vol.28
, pp. 1615-1622
-
-
Arnold, U.1
Ulbrich-Hofmann, R.2
-
7
-
-
27644542234
-
On the track of antitumor ribonucleases
-
Benito A, Ribo M, Vilanova M. On the track of antitumor ribonucleases. Mol BioSyst 2005; 1:294-302.
-
(2005)
Mol BioSyst
, vol.1
, pp. 294-302
-
-
Benito, A.1
Ribo, M.2
Vilanova, M.3
-
8
-
-
38549168927
-
Ribonucleases as novel chemotheraupeutics: The ranpirnase example
-
Lee JE and Raines RT. Ribonucleases as novel chemotheraupeutics: the ranpirnase example. BioDrugs 2008; 22:53-8.
-
(2008)
BioDrugs
, vol.22
, pp. 53-58
-
-
Lee, J.E.1
Raines, R.T.2
-
9
-
-
0026719117
-
Synergism between a novel amphibian oocyte ribonuclease and lovastatin in inducing cytostatic and cytotoxic effects in human lung and pancreatic carcinoma cell lines
-
Mikulski S, Viera A, Darzynkiewicz Z, Shogen K. Synergism between a novel amphibian oocyte ribonuclease and lovastatin in inducing cytostatic and cytotoxic effects in human lung and pancreatic carcinoma cell lines. Br J Cancer 1992; 66:304-10.
-
(1992)
Br J Cancer
, vol.66
, pp. 304-310
-
-
Mikulski, S.1
Viera, A.2
Darzynkiewicz, Z.3
Shogen, K.4
-
10
-
-
0001148620
-
In vitro synergism between a novel amphibian oocytic ribonuclease (ONCONASE) and tamoxifen, lovastatin and cisplatin in human OVCAR-3 ovarian carcinoma cell line
-
Mikulski S, Viera A, Shogen K. In vitro synergism between a novel amphibian oocytic ribonuclease (ONCONASE) and tamoxifen, lovastatin and cisplatin in human OVCAR-3 ovarian carcinoma cell line. Int J Oncol 1992; 1:779-85.
-
(1992)
Int J Oncol
, vol.1
, pp. 779-785
-
-
Mikulski, S.1
Viera, A.2
Shogen, K.3
-
11
-
-
15844415446
-
Enhancement of vincristine cytotoxicity in drug-resistant cells by simultaneous treatment with ONCONASE, an antitumor ribonuclease
-
Rybak SM, Pearson J, Fogler W, Volker K, Spence S, Newton DL, Mikulski SM, Ardelt W, Riggs C, Kung H, Longo D. Enhancement of vincristine cytotoxicity in drug-resistant cells by simultaneous treatment with ONCONASE, an antitumor ribonuclease. JNCI 1996; 88:747-53.
-
(1996)
JNCI
, vol.88
, pp. 747-753
-
-
Rybak, S.M.1
Pearson, J.2
Fogler, W.3
Volker, K.4
Spence, S.5
Newton, D.L.6
Mikulski, S.M.7
Ardelt, W.8
Riggs, C.9
Kung, H.10
Longo, D.11
-
12
-
-
0027256672
-
A cytotoxic ribonuclease. Study of the mechanism of onconase cytotoxicity
-
Wu Y, Mikulski SM, Ardelt W, Rybak SM, Youle RJ. A cytotoxic ribonuclease. Study of the mechanism of onconase cytotoxicity. J Biol Chem 1993; 268:10686-93.
-
(1993)
J Biol Chem
, vol.268
, pp. 10686-10693
-
-
Wu, Y.1
Mikulski, S.M.2
Ardelt, W.3
Rybak, S.M.4
Youle, R.J.5
-
13
-
-
0025020007
-
Striking increase in survival of mice bearing M109 Madison carcinoma treated with a novel protein from amphibian embryos
-
Mikulski SM, Bernstein E, Ardelt W, Shogen K, Menduke K. Striking increase in survival of mice bearing M109 Madison carcinoma treated with a novel protein from amphibian embryos. JNCI 1990; 82:151-3.
-
(1990)
JNCI
, vol.82
, pp. 151-153
-
-
Mikulski, S.M.1
Bernstein, E.2
Ardelt, W.3
Shogen, K.4
Menduke, K.5
-
14
-
-
33847616665
-
Antitumor efficacy of the cytotoxic RNase, ranpirnase, on A549 human lung cancer xenografts of nude mice
-
Lee I, Kalota A, Gewirtz AM, Shogen K. Antitumor efficacy of the cytotoxic RNase, ranpirnase, on A549 human lung cancer xenografts of nude mice. Anticancer Res 2007; 27:299-307.
-
(2007)
Anticancer Res
, vol.27
, pp. 299-307
-
-
Lee, I.1
Kalota, A.2
Gewirtz, A.M.3
Shogen, K.4
-
15
-
-
0036137925
-
Phase II trial of a single weekly intravenous dose of ranpirnase in patients with unresectable malignant mesothelioma
-
Mikulski SM, Constanzi JJ, Vogelzang NJ, McCachren S, Taub RN, Chun H, Mittelman A, Panella T, Puccio C, Fine R, Shogen K. Phase II trial of a single weekly intravenous dose of ranpirnase in patients with unresectable malignant mesothelioma. J Clin Oncol 2002; 20:274-81.
-
(2002)
J Clin Oncol
, vol.20
, pp. 274-281
-
-
Mikulski, S.M.1
Constanzi, J.J.2
Vogelzang, N.J.3
McCachren, S.4
Taub, R.N.5
Chun, H.6
Mittelman, A.7
Panella, T.8
Puccio, C.9
Fine, R.10
Shogen, K.11
-
16
-
-
33344475705
-
Ribonucleases as a novel pro-apoptotic anticancer strategy: Review of the preclinical and clinical data for ranpirnmase
-
Constanzi J, Sidransky D, Navon A, Goldsweig H. Ribonucleases as a novel pro-apoptotic anticancer strategy: review of the preclinical and clinical data for ranpirnmase. Cancer Invest 2005; 23:643-50.
-
(2005)
Cancer Invest
, vol.23
, pp. 643-650
-
-
Constanzi, J.1
Sidransky, D.2
Navon, A.3
Goldsweig, H.4
-
17
-
-
20644466217
-
New agents in the management of advanced mesothelioma
-
Vogelzang NJ, Porta C, Mutt L. New agents in the management of advanced mesothelioma. Semin Oncol 2005; 32:336-50.
-
(2005)
Semin Oncol
, vol.32
, pp. 336-350
-
-
Vogelzang, N.J.1
Porta, C.2
Mutt, L.3
-
18
-
-
33645761337
-
Ranpirnase-an antitumor ribonuclease: Its potential role in malignant mesothelioma
-
Pavlakis N, Vogelzang NJ. Ranpirnase-an antitumor ribonuclease: its potential role in malignant mesothelioma. Expert Opin Biol Ther 2006; 6:1391-9.
-
(2006)
Expert Opin Biol Ther
, vol.6
, pp. 1391-1399
-
-
Pavlakis, N.1
Vogelzang, N.J.2
-
19
-
-
0037439769
-
Secretory ribonucleases are internalized by a dynamin-independent endocytic pathway
-
Haigis MC, Raines RT. Secretory ribonucleases are internalized by a dynamin-independent endocytic pathway. J Cell Sci 2003; 116:313-24.
-
(2003)
J Cell Sci
, vol.116
, pp. 313-324
-
-
Haigis, M.C.1
Raines, R.T.2
-
20
-
-
0037177808
-
Entry into cells and selective degradation of tRNA by a cytotoxic member of the RNase A family
-
Saxena SK, Sirdeshmukh R, Ardelt W, Mikulski SM, Shogen K, Youle RJ. Entry into cells and selective degradation of tRNA by a cytotoxic member of the RNase A family. J Biol Chem 2002; 277:15142-6.
-
(2002)
J Biol Chem
, vol.277
, pp. 15142-15146
-
-
Saxena, S.K.1
Sirdeshmukh, R.2
Ardelt, W.3
Mikulski, S.M.4
Shogen, K.5
Youle, R.J.6
-
21
-
-
0041696477
-
Cytotoxic ribonucleases and RNA interference (RNAi)
-
Ardelt B, Ardelt W, Darzynkiewicz Z. Cytotoxic ribonucleases and RNA interference (RNAi). Cell Cycle 2003; 2:22-4.
-
(2003)
Cell Cycle
, vol.2
, pp. 22-24
-
-
Ardelt, B.1
Ardelt, W.2
Darzynkiewicz, Z.3
-
22
-
-
0031596225
-
KIP and decreased pRb phosphorylation
-
KIP and decreased pRb phosphorylation. Leukemia 1998; 12:1241-8.
-
(1998)
Leukemia
, vol.12
, pp. 1241-1248
-
-
Juan, G.1
Ardelt, B.2
Li, X.3
Mikulski, S.M.4
Shogen, K.5
Ardelt, W.6
Mittelman, A.7
Darzynkiewicz, Z.8
-
23
-
-
0036076883
-
Activation of caspases and serine proteases during apoptosis induced by onconase (Ranpirnase)
-
Grabarek J, Ardelt B, Du L, Darzynkiewicz Z. Activation of caspases and serine proteases during apoptosis induced by onconase (Ranpirnase). Exp Cell Res 2002; 278:61-71.
-
(2002)
Exp Cell Res
, vol.278
, pp. 61-71
-
-
Grabarek, J.1
Ardelt, B.2
Du, L.3
Darzynkiewicz, Z.4
-
24
-
-
0036783252
-
Detection of in situ activation of transglutaminase during apoptosis: Correlation with the cell cycle phase by multiparameter flow- and laser scanning-cytometry
-
Grabarek J, Ardelt B, Kunicki J, Darzynkiewicz Z. Detection of in situ activation of transglutaminase during apoptosis: correlation with the cell cycle phase by multiparameter flow- and laser scanning-cytometry. Cytometry 2002; 49:83-9.
-
(2002)
Cytometry
, vol.49
, pp. 83-89
-
-
Grabarek, J.1
Ardelt, B.2
Kunicki, J.3
Darzynkiewicz, Z.4
-
25
-
-
38149109693
-
Cytostatic and cytotoxic properties of Amphinase, a novel cytotoxic ribonuclease from Rana pipiens oocytes
-
Ardelt B, Ardelt W, Pozarowski P, Kunicki J, Shogen K, Darzynkiewicz Z. Cytostatic and cytotoxic properties of Amphinase, a novel cytotoxic ribonuclease from Rana pipiens oocytes. Cell Cycle 2007; 6:3097-102.
-
(2007)
Cell Cycle
, vol.6
, pp. 3097-3102
-
-
Ardelt, B.1
Ardelt, W.2
Pozarowski, P.3
Kunicki, J.4
Shogen, K.5
Darzynkiewicz, Z.6
-
26
-
-
0031036984
-
Cytometry in cell necrobiology. Analysis of apoptosis and accidental cell death (necrosis)
-
Darzynkiewicz Z, Juan G, Li X, Gorczyca W, Murakami Traganos F. Cytometry in cell necrobiology. Analysis of apoptosis and accidental cell death (necrosis). Cytometry 1997; 27:1-20.
-
(1997)
Cytometry
, vol.27
, pp. 1-20
-
-
Darzynkiewicz, Z.1
Juan, G.2
Li, X.3
Gorczyca, W.4
Murakami Traganos, F.5
-
27
-
-
0026719117
-
Synergism between a novel amphibian oocyte ribonuclease and lovastatin in inducing cytostatic and cytotoxic effects in human lung and pancreatic carcinoma cell lines
-
Mikulski SM, Viera A, Darzynkiewicz Z. Synergism between a novel amphibian oocyte ribonuclease and lovastatin in inducing cytostatic and cytotoxic effects in human lung and pancreatic carcinoma cell lines. Br J Cancer 1992; 66:304-10.
-
(1992)
Br J Cancer
, vol.66
, pp. 304-310
-
-
Mikulski, S.M.1
Viera, A.2
Darzynkiewicz, Z.3
-
28
-
-
0031861178
-
Potentiation of tumor necrosis factor induced apoptosis by onconase
-
Deptala A, Halicka HD, Ardelt W, Mikulski SM, Shogen K, Darzynkiewicz Z. Potentiation of tumor necrosis factor induced apoptosis by onconase. Int J Oncol 1998; 13:11-6.
-
(1998)
Int J Oncol
, vol.13
, pp. 11-16
-
-
Deptala, A.1
Halicka, H.D.2
Ardelt, W.3
Mikulski, S.M.4
Shogen, K.5
Darzynkiewicz, Z.6
-
29
-
-
0036583053
-
Combined effects of onconase and IFNbeta on proliferation, macromolecular syntheses and expression of STAT-1 in JCA-1 cancer cells
-
Tsai SY, Hsieh TC, Ardelt B, Darzynkiewicz Z, Wu JM. Combined effects of onconase and IFNbeta on proliferation, macromolecular syntheses and expression of STAT-1 in JCA-1 cancer cells. Int J Oncol 2002; 20:891-6.
-
(2002)
Int J Oncol
, vol.20
, pp. 891-896
-
-
Tsai, S.Y.1
Hsieh, T.C.2
Ardelt, B.3
Darzynkiewicz, Z.4
Wu, J.M.5
-
30
-
-
84934444689
-
Possible mechanisms of improved response by cytotoxic RNase, Onconase, on 549 human lung cancer xenografts of nude mice
-
Kim DH, Kim EJ, Kalota A, Gewirtz AA, Glickson J, Shogen H, Lee I. Possible mechanisms of improved response by cytotoxic RNase, Onconase, on 549 human lung cancer xenografts of nude mice. Adv Exp Biol Med 2007; 599:53-9.
-
(2007)
Adv Exp Biol Med
, vol.599
, pp. 53-59
-
-
Kim, D.H.1
Kim, E.J.2
Kalota, A.3
Gewirtz, A.A.4
Glickson, J.5
Shogen, H.6
Lee, I.7
-
31
-
-
0033678736
-
Induction of differentiation of leukemic (HL-60) or prostate cancer (LNCaP, JCA-1) cells potentiates frequency of apoptosis triggered by onconase
-
Halicka HD, Murakami T, Papageorgio CN, Mittelman A, Mikulski SM, Shogen K, Darzynkiewicz Z. Induction of differentiation of leukemic (HL-60) or prostate cancer (LNCaP, JCA-1) cells potentiates frequency of apoptosis triggered by onconase. Cell Prolif 2000; 33:407-17.
-
(2000)
Cell Prolif
, vol.33
, pp. 407-417
-
-
Halicka, H.D.1
Murakami, T.2
Papageorgio, C.N.3
Mittelman, A.4
Mikulski, S.M.5
Shogen, K.6
Darzynkiewicz, Z.7
-
32
-
-
34247891723
-
Mild hyperthermia predisposes tumor cells to undergo apoptosis upon treatment with onconase
-
Halicka HD, Ardelt B, Shogen K, Darzynkiewicz Z. Mild hyperthermia predisposes tumor cells to undergo apoptosis upon treatment with onconase. Int J Oncol 2007; 30:841-7.
-
(2007)
Int J Oncol
, vol.30
, pp. 841-847
-
-
Halicka, H.D.1
Ardelt, B.2
Shogen, K.3
Darzynkiewicz, Z.4
-
33
-
-
0029992609
-
Suppression of TNFα-induced apoptosios by NFκB
-
Van Antwerp DJ, Martin SJ, Kafri T, Green DG, Verma IM. Suppression of TNFα-induced apoptosios by NFκB. Science 1996; 274:787-9.
-
(1996)
Science
, vol.274
, pp. 787-789
-
-
Van Antwerp, D.J.1
Martin, S.J.2
Kafri, T.3
Green, D.G.4
Verma, I.M.5
-
34
-
-
0029858387
-
TNF and cancer therapy-induced apoptosis: Potentiation by inhibition of NFκB
-
Wang CY, Mayo MM, Baldwin AS Jr. TNF and cancer therapy-induced apoptosis: potentiation by inhibition of NFκB. Science 1996; 274:784-7.
-
(1996)
Science
, vol.274
, pp. 784-787
-
-
Wang, C.Y.1
Mayo, M.M.2
Baldwin Jr, A.S.3
-
35
-
-
0029976817
-
An essential role for NFκB in preventing TNFα induced cell death
-
Begg AA, Baltimore D. An essential role for NFκB in preventing TNFα induced cell death. Science 1996; 274:782-4.
-
(1996)
Science
, vol.274
, pp. 782-784
-
-
Begg, A.A.1
Baltimore, D.2
-
36
-
-
33846940700
-
The effects of biscoclaurine alkaloid cepharanthine on mammalian cells: Implications for cancer, shock and inflammatory diseases
-
Furusawa S, Wu J. The effects of biscoclaurine alkaloid cepharanthine on mammalian cells: implications for cancer, shock and inflammatory diseases. Life Sciences 2007; 80:1073-9.
-
(2007)
Life Sciences
, vol.80
, pp. 1073-1079
-
-
Furusawa, S.1
Wu, J.2
-
37
-
-
0036808027
-
Seventeen cases of alopecia areata: Combination of SADBE topical immunotherapy with other therapies
-
Morita K, Nakamura M, Nagamachi M, Kishi T, Miyachi Y. Seventeen cases of alopecia areata: combination of SADBE topical immunotherapy with other therapies. J Dermatol 2002; 29:661-4.
-
(2002)
J Dermatol
, vol.29
, pp. 661-664
-
-
Morita, K.1
Nakamura, M.2
Nagamachi, M.3
Kishi, T.4
Miyachi, Y.5
-
38
-
-
0031371323
-
Therapeutic experience of venomous snakebites by the Japanese viper (Agkistrodon halys blomhoffii) with low dose of antivenin: Report of 43 consecutive cases
-
Kimoto T, Suemitsu K, Nakayama H, Komori E, Ohtani M, Ando S. Therapeutic experience of venomous snakebites by the Japanese viper (Agkistrodon halys blomhoffii) with low dose of antivenin: report of 43 consecutive cases. Nippon Geka Hokan 1997; 66:71-7.
-
(1997)
Nippon Geka Hokan
, vol.66
, pp. 71-77
-
-
Kimoto, T.1
Suemitsu, K.2
Nakayama, H.3
Komori, E.4
Ohtani, M.5
Ando, S.6
-
39
-
-
0025337656
-
Effect of cepharanthin on radiotherapy induced leucopenia
-
Ohta T, Morita K. Effect of cepharanthin on radiotherapy induced leucopenia. Rinsho Hoshasen 1990; 35:471-4.
-
(1990)
Rinsho Hoshasen
, vol.35
, pp. 471-474
-
-
Ohta, T.1
Morita, K.2
-
40
-
-
34247898769
-
Antimalarial activity of alkaloids isolated from Stephania rotunda
-
Chea A, Hout S, Bun SS, Tabatadze N, Gasquet M, Azas N, Elias R, Balansard G. Antimalarial activity of alkaloids isolated from Stephania rotunda. J Ethnopharmacol 2007; 12:132-7.
-
(2007)
J Ethnopharmacol
, vol.12
, pp. 132-137
-
-
Chea, A.1
Hout, S.2
Bun, S.S.3
Tabatadze, N.4
Gasquet, M.5
Azas, N.6
Elias, R.7
Balansard, G.8
-
41
-
-
0025824159
-
Cepharanthine (biscoclaurine alkaloid) treatment in endotoxic shock of suckling rats
-
Goto M, Zeller WP, Hurley RM. Cepharanthine (biscoclaurine alkaloid) treatment in endotoxic shock of suckling rats. J Pharm Pharmacol 1991; 43:589-91.
-
(1991)
J Pharm Pharmacol
, vol.43
, pp. 589-591
-
-
Goto, M.1
Zeller, W.P.2
Hurley, R.M.3
-
42
-
-
0019988987
-
In vitro anti-sickling effect on cepharanthine
-
Sato T, Ohnishi ST. In vitro anti-sickling effect on cepharanthine. Eur J Pharmacol 1982; 83:91-5.
-
(1982)
Eur J Pharmacol
, vol.83
, pp. 91-95
-
-
Sato, T.1
Ohnishi, S.T.2
-
43
-
-
0019291607
-
Inhibition by biscoclaurine alkaloid of lipid peroxidation in biological membranes
-
Shiraishi N, Arima T, Aono K, Inouye B, Morimoto Y, Utsumi K. Inhibition by biscoclaurine alkaloid of lipid peroxidation in biological membranes. Physiol Chem Physics 1980; 12:299-305.
-
(1980)
Physiol Chem Physics
, vol.12
, pp. 299-305
-
-
Shiraishi, N.1
Arima, T.2
Aono, K.3
Inouye, B.4
Morimoto, Y.5
Utsumi, K.6
-
44
-
-
0027052766
-
Histamine release inhibition activity of bisbenzylisoquinoline alkaloids
-
Nakamura K, Tsuchiya S, Sugimoto Y, Sugimura Y, Yamada Y. Histamine release inhibition activity of bisbenzylisoquinoline alkaloids. Planta Medica 1992; 58:505-8.
-
(1992)
Planta Medica
, vol.58
, pp. 505-508
-
-
Nakamura, K.1
Tsuchiya, S.2
Sugimoto, Y.3
Sugimura, Y.4
Yamada, Y.5
-
45
-
-
0023574608
-
Mode of the anti-allergic action of cepharanthine on an experimental model of allergic rhinitis
-
Kohno H, Inoue H, Seyama Y, Yamashita S, Akasu M. Mode of the anti-allergic action of cepharanthine on an experimental model of allergic rhinitis. Nippon Yakurigaku Zasshi 1987; 90:205-11.
-
(1987)
Nippon Yakurigaku Zasshi
, vol.90
, pp. 205-211
-
-
Kohno, H.1
Inoue, H.2
Seyama, Y.3
Yamashita, S.4
Akasu, M.5
-
46
-
-
0025611415
-
Reversal of resistance to doxorubicin with cepharanthine in murine P388 leukemia cells
-
Fujimura T, Shibata H, Maekawa I, Furusawa S, Kawauchi H, Sasaki K, Takayanagi Y. Reversal of resistance to doxorubicin with cepharanthine in murine P388 leukemia cells. Japan J Pharmacol 1990; 54:464-7.
-
(1990)
Japan J Pharmacol
, vol.54
, pp. 464-467
-
-
Fujimura, T.1
Shibata, H.2
Maekawa, I.3
Furusawa, S.4
Kawauchi, H.5
Sasaki, K.6
Takayanagi, Y.7
-
47
-
-
0035053728
-
Pharmacological characterization of cepharanthin in chronic idiopathic thrombocytopenic purpura
-
Sato T, Morita I, Fujita H, Ono M, Kimishima A, Tomiyama J, Murota S. Pharmacological characterization of cepharanthin in chronic idiopathic thrombocytopenic purpura. Platelets 2001; 12:156-62.
-
(2001)
Platelets
, vol.12
, pp. 156-162
-
-
Sato, T.1
Morita, I.2
Fujita, H.3
Ono, M.4
Kimishima, A.5
Tomiyama, J.6
Murota, S.7
-
49
-
-
0025789059
-
Cepharanthine inhibits twostage tumor promotion by 12-O-tetradecanoylphorbol 13-acetate and mezerein on skin tumor formation in mice initiated with 7, 12-dimethylbenz[á] anthracene
-
Yasukawa K, Takido M, Takeuchi M, Akasu M, Nakagawa S. Cepharanthine inhibits twostage tumor promotion by 12-O-tetradecanoylphorbol 13-acetate and mezerein on skin tumor formation in mice initiated with 7, 12-dimethylbenz[á] anthracene. J Cancer Res Clin Oncol 1991; 117:421-4.
-
(1991)
J Cancer Res Clin Oncol
, vol.117
, pp. 421-424
-
-
Yasukawa, K.1
Takido, M.2
Takeuchi, M.3
Akasu, M.4
Nakagawa, S.5
-
50
-
-
0032929699
-
Potent antiperoxidation activity of the bisbenzylisoquinoline alkaloid cepharanthine: The amine moiety is responsible for its pH-dependent radical scavenge activity
-
Kogure K, Goto S, Abe K, Ohiwa C, Akasu M, Terada H. Potent antiperoxidation activity of the bisbenzylisoquinoline alkaloid cepharanthine: the amine moiety is responsible for its pH-dependent radical scavenge activity. Biochim Biophys Acta 1999; 1426:133-42.
-
(1999)
Biochim Biophys Acta
, vol.1426
, pp. 133-142
-
-
Kogure, K.1
Goto, S.2
Abe, K.3
Ohiwa, C.4
Akasu, M.5
Terada, H.6
-
51
-
-
0038095189
-
Direct radical scavenging by the bisbenzylisoquinoline alkaloid cepharanthine
-
Kogure K, Tsuchiya K, Abe K, Akasu M, Tamaki T, Fukuzawa K, Terada H. Direct radical scavenging by the bisbenzylisoquinoline alkaloid cepharanthine. Biochim Biophys Acta 2003; 1622:1-5.
-
(2003)
Biochim Biophys Acta
, vol.1622
, pp. 1-5
-
-
Kogure, K.1
Tsuchiya, K.2
Abe, K.3
Akasu, M.4
Tamaki, T.5
Fukuzawa, K.6
Terada, H.7
-
52
-
-
0034779880
-
Protection of T cells from radiation-induced apoptosis by Cepharantin
-
Oyaizu H, Adachi Y, Yasumizu R, Ono M, Ikebukuru K, Fukuhara S, Ikahara S. Protection of T cells from radiation-induced apoptosis by Cepharantin. Int J Immunopharmacol 2001; 1:2091-9.
-
(2001)
Int J Immunopharmacol
, vol.1
, pp. 2091-2099
-
-
Oyaizu, H.1
Adachi, Y.2
Yasumizu, R.3
Ono, M.4
Ikebukuru, K.5
Fukuhara, S.6
Ikahara, S.7
-
53
-
-
42549096557
-
The biscoclaurine alkaloid cepharanthine protects DNA in TK6 lymphoblastoid cells from constitutive oxidative damage
-
Halicka HD, Ita M, Tanaka T, Kurose A, Darzynkiewicz Z. The biscoclaurine alkaloid cepharanthine protects DNA in TK6 lymphoblastoid cells from constitutive oxidative damage. Pharmacol Rep 2008; 60:93-100.
-
(2008)
Pharmacol Rep
, vol.60
, pp. 93-100
-
-
Halicka, H.D.1
Ita, M.2
Tanaka, T.3
Kurose, A.4
Darzynkiewicz, Z.5
-
54
-
-
35948985547
-
Cytometric assessment of DNA damage by exogenous and endogenous oxidants reports the aging-related processes
-
Zhao H, Tanaka T, Halicka HD, Traganos F, Zarebski M, Dobrucki J, Darzynkiewicz Z. Cytometric assessment of DNA damage by exogenous and endogenous oxidants reports the aging-related processes. Cytometry A 2007; 71:905-14.
-
(2007)
Cytometry A
, vol.71
, pp. 905-914
-
-
Zhao, H.1
Tanaka, T.2
Halicka, H.D.3
Traganos, F.4
Zarebski, M.5
Dobrucki, J.6
Darzynkiewicz, Z.7
-
55
-
-
35848957914
-
Cepharanthinenhanced radiosensitivity through the inhibition of radiation-induced nuclear factor-kappaB activity in human oral carcinoma calls
-
Tamatami T, Azuma M, Motegi K, Takamaru N, Kawashima Y, Bando T. Cepharanthinenhanced radiosensitivity through the inhibition of radiation-induced nuclear factor-kappaB activity in human oral carcinoma calls. Int J Oncol 2007; 31:761-8.
-
(2007)
Int J Oncol
, vol.31
, pp. 761-768
-
-
Tamatami, T.1
Azuma, M.2
Motegi, K.3
Takamaru, N.4
Kawashima, Y.5
Bando, T.6
-
56
-
-
38449086203
-
Onconase, an anti-tumor ribonuclease suppresses oxidative stress
-
Ardelt B, Juan G, Burfeind P, Salomon T, Wu JM, Hsieh TC, Li X, Sperry R, Pozarowski P, Shogen K, Ardelt W, Darzynkiewicz Z. Onconase, an anti-tumor ribonuclease suppresses oxidative stress. Int J Oncol 2007; 31:663-9.
-
(2007)
Int J Oncol
, vol.31
, pp. 663-669
-
-
Ardelt, B.1
Juan, G.2
Burfeind, P.3
Salomon, T.4
Wu, J.M.5
Hsieh, T.C.6
Li, X.7
Sperry, R.8
Pozarowski, P.9
Shogen, K.10
Ardelt, W.11
Darzynkiewicz, Z.12
-
57
-
-
34249302795
-
Sustained activation of nuclear factorκB by reactive oxygen species is involved in the pathogenesis of stress-induces gastric damage in rats
-
Jia YT, Ma B, Wei W, Xu Y, Wang Y, Tang HT, Xia ZF. Sustained activation of nuclear factorκB by reactive oxygen species is involved in the pathogenesis of stress-induces gastric damage in rats. Crit Care Med 2007; 35:1582-89.
-
(2007)
Crit Care Med
, vol.35
, pp. 1582-1589
-
-
Jia, Y.T.1
Ma, B.2
Wei, W.3
Xu, Y.4
Wang, Y.5
Tang, H.T.6
Xia, Z.F.7
-
58
-
-
0028980212
-
Activation of NFkappaB in human skin fibroblasts by the oxidative stress generated by UVA radiation
-
Vile GF, Tanef-Ilitschew A, Tyrrel RM. Activation of NFkappaB in human skin fibroblasts by the oxidative stress generated by UVA radiation. Photochem Photobiol 1995; 62:463-8.
-
(1995)
Photochem Photobiol
, vol.62
, pp. 463-468
-
-
Vile, G.F.1
Tanef-Ilitschew, A.2
Tyrrel, R.M.3
-
59
-
-
33947363238
-
Nicotine induces oxidative stress and activates nuclear transcription factor kappa B in rat mesencephalic cells
-
Barr J, Sharma CS, Sarkar S, Wise K, Dong L, Peryakaruppan A, Ramesh GT. Nicotine induces oxidative stress and activates nuclear transcription factor kappa B in rat mesencephalic cells. Mol Cell Biochem 2007; 297:93-9.
-
(2007)
Mol Cell Biochem
, vol.297
, pp. 93-99
-
-
Barr, J.1
Sharma, C.S.2
Sarkar, S.3
Wise, K.4
Dong, L.5
Peryakaruppan, A.6
Ramesh, G.T.7
-
60
-
-
0030660501
-
Multiple redox regulation in NFkappaB transcription factor activation
-
Piette J, Piret B, Bonizzi G, Schoonbroodt S, Merville MP, Legrand-Poels S, Bours V. Multiple redox regulation in NFkappaB transcription factor activation. Biol Chem 1997; 378:1237-45.
-
(1997)
Biol Chem
, vol.378
, pp. 1237-1245
-
-
Piette, J.1
Piret, B.2
Bonizzi, G.3
Schoonbroodt, S.4
Merville, M.P.5
Legrand-Poels, S.6
Bours, V.7
-
61
-
-
0001513802
-
DNA strand breaks occurring during apoptosis: Their early in situ detection by the terminal deoxynucleotidyl transferase and nick translation assays and prevention by serine protease inhibitors
-
Gorczyca W, Bruno S, Darzynkiewicz RJ, Gong J, Darzynkiewicz Z. DNA strand breaks occurring during apoptosis: Their early in situ detection by the terminal deoxynucleotidyl transferase and nick translation assays and prevention by serine protease inhibitors. Int J Oncol 1992; 1:639-48.
-
(1992)
Int J Oncol
, vol.1
, pp. 639-648
-
-
Gorczyca, W.1
Bruno, S.2
Darzynkiewicz, R.J.3
Gong, J.4
Darzynkiewicz, Z.5
-
62
-
-
39749163470
-
Analysis of apoptosis by cytometry using TUNEL assay
-
Darzynkiewicz Z, Galkowski D, Zhao H. Analysis of apoptosis by cytometry using TUNEL assay. Methods 2008; 44:250-4.
-
(2008)
Methods
, vol.44
, pp. 250-254
-
-
Darzynkiewicz, Z.1
Galkowski, D.2
Zhao, H.3
-
63
-
-
0021118703
-
Quantitative analysis of the dose-effect relationship: The combined effects of multiple drugs or enzyme inhibitors
-
Chou TC, Talalay P. Quantitative analysis of the dose-effect relationship: the combined effects of multiple drugs or enzyme inhibitors. Adv Enz Regul 1984; 22:27-55.
-
(1984)
Adv Enz Regul
, vol.22
, pp. 27-55
-
-
Chou, T.C.1
Talalay, P.2
-
64
-
-
37049019490
-
MicroRNAs as potential agents to alter resistance to cytotoxic anticancer therapy
-
Weidhaas JB, Babar I, Nallur SM, Trang P, Roush S, Boehm M, Gillespie E, Slack FJ. MicroRNAs as potential agents to alter resistance to cytotoxic anticancer therapy. Cancer Res 2007; 67:11111-6.
-
(2007)
Cancer Res
, vol.67
, pp. 11111-11116
-
-
Weidhaas, J.B.1
Babar, I.2
Nallur, S.M.3
Trang, P.4
Roush, S.5
Boehm, M.6
Gillespie, E.7
Slack, F.J.8
-
65
-
-
37049010980
-
The guardian's little helper: MicroRNAs in the p53 tumor suppressor network
-
He X, He L, Hannon GJ. The guardian's little helper: microRNAs in the p53 tumor suppressor network. Cancer Res 2007; 67:11099-105.
-
(2007)
Cancer Res
, vol.67
, pp. 11099-11105
-
-
He, X.1
He, L.2
Hannon, G.J.3
-
67
-
-
34250647098
-
Telomerase RNA levels limit the telomere length equilibrium
-
Greider CW. Telomerase RNA levels limit the telomere length equilibrium Cold Spring Harb Symp Quant Biol 2006; 71:225-9.
-
(2006)
Cold Spring Harb Symp Quant Biol
, vol.71
, pp. 225-229
-
-
Greider, C.W.1
-
68
-
-
0029874138
-
The NFκB and IκB proteins: New discoveries and insights
-
Baldwin AS Jr. The NFκB and IκB proteins: New discoveries and insights. Annu Rev Immunol 1996; 14:649-83.
-
(1996)
Annu Rev Immunol
, vol.14
, pp. 649-683
-
-
Baldwin Jr., A.S.1
-
69
-
-
0023112619
-
Effect of recombinant tumor necrosis factor on HL-60 cells: Cell cycle specificity and synergism with actinomycin D
-
Darzynkiewicz Z, Carter SP, Old LJ. Effect of recombinant tumor necrosis factor on HL-60 cells: cell cycle specificity and synergism with actinomycin D. J Cell Physiol 1987; 130:328-35.
-
(1987)
J Cell Physiol
, vol.130
, pp. 328-335
-
-
Darzynkiewicz, Z.1
Carter, S.P.2
Old, L.J.3
-
70
-
-
28944444198
-
Nuclear factorκB
-
Zingarelli N. Nuclear factorκB. Crit Care Med 2005; 33:414-6.
-
(2005)
Crit Care Med
, vol.33
, pp. 414-416
-
-
Zingarelli, N.1
|