Potent antiperoxidation activity of the bisbenzylisoquinoline alkaloid cepharanthine: The amine moiety is responsible for its pH-dependent radical scavenge activity

Biochimica et Biophysica Acta - General Subjects

Volumn 1426, Issue 1, 1999, Pages 133-142

  Kogure, Kentaro ^a   Goto, Satoru ^a   Abe, Kazutoyo ^a   Ohiwa, Chie ^a   Akasu, Michinori ^b   Terada, Hiroshi ^a  

^a UNIVERSITY OF TOKUSHIMA   (Japan)

^b Kaken Shoyaku Co Ltd   (Japan)

Author keywords

Bisbenzylisoquinoline alkaloid; Cepharanthine; Lipid peroxidation; Radical scavenger

Indexed keywords

1,1 DIPHENYL 2 PICRYLHYDRAZYL; ALPHA TOCOPHEROL; BISBENZYLISOQUINOLINE ALKALOID; CEPHARANTHINE; LIPOSOME; RADICAL;

ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; ELECTRON SPIN RESONANCE; IN VITRO STUDY; LIPID PEROXIDATION; LIVER MITOCHONDRION; MALE; MEMBRANE FLUIDITY; NONHUMAN; OXYGEN CONSUMPTION; PH; PRIORITY JOURNAL; RAT; STRUCTURE ACTIVITY RELATION;

ALKALOIDS; AMINES; ANIMALS; ANTIOXIDANTS; BEPRIDIL; FREE RADICAL SCAVENGERS; HYDROGEN-ION CONCENTRATION; LIPID PEROXIDATION; MALE; MEMBRANE FLUIDITY; MITOCHONDRIA, LIVER; PICRATES; RATS; RATS, WISTAR;

EID: 0032929699     PISSN: 03044165     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-4165(98)00146-9     Document Type: Article

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