Pichia stipitis xylose reductase helps detoxifying lignocellulosic hydrolysate by reducing 5-hydroxymethyl-furfural (HMF)

Biotechnology for Biofuels

Volumn 1, Issue , 2008, Pages

  Almeida, João R M ^a   Modig, Tobias ^a   Röder, Anja ^a,b   Lidén, Gunnar ^a   Gorwa Grauslund, Marie F ^a  

^a LUND UNIVERSITY   (Sweden)

^b UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

5 HYDROXYMETHYL FURFURAL (HMF); ANAEROBIC (UASB); BATCH FERMENTATIONS; CONTROL STRAIN; CONVERSION RATES; FURALDEHYDE; IN-VITRO; IN-VIVO; LIGNOCELLULOSIC HYDROLYSATES; OVER-EXPRESSION; PICHIA STIPITIS; REDUCTION ACTIVITY; S. CEREVISIAE; SACCHAROMYCES CEREVISIAE STRAINS; XYLOSE REDUCTASE (XR);

ALDEHYDES; ARSENIC COMPOUNDS; BIOCHEMICAL ENGINEERING; ENZYMES; FERMENTATION; FOOD ADDITIVES; FURFURAL; METHANOL; SUGAR SUBSTITUTES;

STRAIN;

DETOXIFICATION; FERMENTATION; SUGAR; YEAST;

PICHIA STIPITIS; SACCHAROMYCES CEREVISIAE;

EID: 47949108963     PISSN: None     EISSN: None     Source Type: Journal    
DOI: 10.1186/1754-6834-1-12     Document Type: Article

References (36)

1. Hahn-Hägerdal B Karhumaa K Fonseca C Spencer-Martins I Gorwa-Grauslund MF Towards industrial pentose-fermenting yeast strains Applied Microbiology and Biotechnology 2007, 74:937-953. 10.1007/ s00253-006-0827-2 17294186
2. Almeida JRM Modig T Petersson A Hahn-Hägerdal B Lidén G Gorwa-Grauslund MF Increased tolerance and conversion of inhibitors in lignocellulosic hydrolysates by Saccharomyces cerevisiae Journal of Chemical Technology & Biotechnology 2007, 82:340-349. 10.1002/ jctb.1676
3. Chu BC Lee H Genetic improvement of Saccharomyces cerevisiae for xylose fermentation Biotechnol Adv 2007. 17524590
4. Öhgren K Bengtsson O Gorwa-Grauslund MF Galbe M Hahn-Hägerdal B Zacchi G Simultaneous saccharification and co-fermentation of glucose and xylose in steam-pretreated corn stover at high fiber content with Saccharomyces cerevisiae TMB3400 J Biotechnol 2006, 126:488-98. 16828190 10.1016/j.jbiotec.2006.05.001
5. Olsson L Soerensen HR Dam BP Christensen H Krogh KM Meyer AS Separate and simultaneous enzymatic hydrolysis and fermentation of wheat hemicellulose with recombinant xylose utilizing Saccharomyces cerevisiae Appl Biochem Biotechnol 2006, 129-132:117-129. 10.1385/ABAB:129:1:117 16915635
6. Sedlak M Ho NW Production of ethanol from cellulosic biomass hydrolysates using genetically engineered Saccharomyces yeast capable of cofermenting glucose and xylose Appl Biochem Biotechnol 2004, 113-116:403-416. 10.1385/ABAB:114:1-3:403 15054267
7. Hahn-Hägerdal B Pamment N Microbial pentose metabolism Appl Biochem Biotechnol 2004, 113-116:1207-1209. 10.1385/ABAB:116:1-3:1207 15054228
8. Katahira S Mizuike A Fukuda H Kondo A Ethanol fermentation from lignocellulosic hydrolysate by a recombinant xylose- and cellooligosaccharide-assimilating yeast strain Appl Microbiol Biotechnol 2006, 72:1136-1143. 10.1007/s00253-006-0402-x 16575564
9. Palmqvist E Hahn-Hägerdal B Fermentation of lignocellulosic hydrolysates. II: Inhibitors and mechanisms of inhibition Bioresource Technology 2000, 74:25-33. 10.1016/S0960-8524(99)00161-3
10. Klinke HB Thomsen AB Ahring BK Inhibition of ethanol-producing yeast and bacteria by degradation products produced during pre-treatment of biomass Appl Microbiol Biotechnol 2004, 66:10-26. 10.1007/ s00253-004-1642-2 15300416
11. Verduyn C Postma E Scheffers WA Van Dijken JP Effect of benzoic acid on metabolic fluxes in yeasts: A continuous-culture study on the regulation of respiration and alcoholic fermentation Yeast 1992, 8:501-517. 10.1002/ yea.320080703 1523884
12. Petersson A Almeida JRM Modig T Karhumaa K Hahn-Hägerdal B Gorwa-Grauslund MF Liden G A 5-hydroxymethyl furfural reducing enzyme encoded by the Saccharomyces cerevisiae ADH6 gene conveys HMF tolerance Yeast 2006, 23:455-464. 10.1002/yea.1370 16652391
13. Liu ZL Slininger PJ Dien BS Berhow MA Kurtzman CP Gorsich SW Adaptive response of yeasts to furfural and 5-hydroxymethylfurfural and new chemical evidence for HMF conversion to 2,5-bis-hydroxymethylfuran J Ind Microbiol Biotechnol 2004, 31:345-352. 15338422
14. Larsson S Nilvebrant NO Jonsson LJ Effect of overexpression of Saccharomyces cerevisiae Pad1p on the resistance to phenylacrylic acids and lignocellulose hydrolysates under aerobic and oxygen-limited conditions Appl Microbiol Biotechnol 2001, 57:167-174. 11693915
15. Larsson S Cassland P Jonsson LJ Development of a Saccharomyces cerevisiae strain with enhanced resistance to phenolic fermentation inhibitors in lignocellulose hydrolysates by heterologous expression of laccase Appl Environ Microbiol 2001, 67:1163-1170. 92709 11229906 10.1128/AEM.67.3.1163-1170.2001
16. Modig T Almeida JRM Gorwa-Grauslund MF Liden G Variability of Saccharomyces cerevisiae strain response to lignocellulose hydrolysate Biotechnology and Bioengineering 2008. 10.1002/bit.21789
17. Nilsson A Gorwa-Grauslund MF Hahn-Hägerdal B Liden G Cofactor dependence in furan reduction by Saccharomyces cerevisiae in fermentation of acid-hydrolyzed lignocellulose Appl Environ Microbiol 2005, 71:7866-7871. 1317483 16332761 10.1128/AEM.71.12.7866-7871.2005
18. Almeida JRM Röder A Modig T Laadan B Lidén G Gorwa-Grauslund MF NADH- vs. NADPH-coupled reduction of 5-hydroxymethyl-furfural (HMF) and its implications on product distribution in Saccharomyces cerevisiae Appl Microbiol Biotechnol 2008, 78(6):939-45. 101007/s00253-008-1364 18330568
19. Laadan B Almeida JR Radstrom P Hahn-Hägerdal B Gorwa-Grauslund M Identification of an NADH-dependent 5-hydroxymethylfurfural-reducing alcohol dehydrogenase in Saccharomyces cerevisiae Yeast 2008, 25:191-198. 10.1002/yea.1578 18302314
20. Wahlbom CF van Zyl WH Jonsson LJ Hahn-Hägerdal B Otero RR Generation of the improved recombinant xylose-utilizing Saccharomyces cerevisiae TMB 3400 by random mutagenesis and physiological comparison with Pichia stipitis CBS 6054 FEMS Yeast Res 2003, 3:319-326. 10.1016/ S1567-1356(02)00206-4 12689639
21. Verduyn C Van Kleef R Frank J Schreuder H Van Dijken JP Scheffers WA Properties of the NAD(P)H-dependent xylose reductase from the xylose-fermenting yeast Pichia stipitis Biochem J 1985, 226:669-677. 1144764 3921014
22. Jeppsson M Traff K Johansson B Hahn-Hägerdal B Gorwa-Grauslund MF Effect of enhanced xylose reductase activity on xylose consumption and product distribution in xylose-fermenting recombinant Saccharomyces cerevisiae FEMS Yeast Res 2003, 3:167-175. 10.1016/S1567-1356(02)00186-1 12702449
23. Rizzi M Erlemann P Bui-Thanh N-A Dellweg H Xylose fermentation by yeasts. 4. Purification and kinetic studies of xylose reductase from Pichia stipitis Applied Microbiology and Biotechnology 1988, 29:148-154.
24. Eisenthal R Enzyme Assays: A Practical Approach Oxford: Oxford University Press 1992.
25. Amore R Kotter P Kuster C Ciriacy M Hollenberg CP Cloning and expression in Saccharomyces cerevisiae of the NAD(P)H-dependent xylose reductase-encoding gene (XYL1) from the xylose-assimilating yeast Pichia stipitis Gene 1991, 109:89-97. 10.1016/0378-1119(91)90592-Y 1756986
26. Hallborn J Walfridsson M Airaksinen U Ojamo H Hahn-Hägerdal B Penttila M Kerasnen S Xylitol production by recombinant Saccharomyces cerevisiae Biotechnology (N Y) 1991, 9:1090-1095. 10.1038/nbt1191-1090 1367625
27. Takuma S Nakashima N Tantirungkij M Kinoshita S Okada H Seki T Yoshida T Isolation of xylose reductase gene of Pichia stipitis and its expression in Saccharomyces cerevisiae Appl Biochem Biotechnol 1991, 28-29:327-340. 1929370 10.1007/BF02922612
28. Taherzadeh MJ Gustafsson L Niklasson C Liden G Physiological effects of 5-hydroxymethylfurfural on Saccharomyces cerevisiae Appl Microbiol Biotechnol 2000, 53:701-708. 10.1007/s002530000328 10919330
29. Modig T Liden G Taherzadeh MJ Inhibition effects of furfural on alcohol dehydrogenase, aldehyde dehydrogenase and pyruvate dehydrogenase Biochem J 2002, 363:769-776. 1222530 11964178 10.1042/0264-6021:3630769
30. Taherzadeh MJ Liden G Gustafsson L Niklasson C The effects of pantothenate deficiency and acetate addition on anaerobic batch fermentation of glucose by Saccharomyces cerevisiae Appl Microbiol Biotechnol 1996, 46:176-182. 10.1007/s002530050801 8987648
31. Nilsson A Taherzadeh MJ Liden G Use of dynamic step response for control of fed-batch conversion of lignocellulosic hydrolyzates to ethanol J Biotechnol 2001, 89:41-53. 10.1016/S0168-1656(01)00283-8 11472798
32. Smiley K Bolen P Demonstration of D-xylose reductase and D-xylitol dehydrogenase in Pachysolen tannophilus Biotechnol Lett 1982, 9.
33. Wahlbom CF Hahn-Hägerdal B Furfural, 5-hydroxymethyl furfural, and acetoin act as external electron acceptors during anaerobic fermentation of xylose in recombinant Saccharomyces cerevisiae Biotechnol Bioeng 2002, 78:172-178. 10.1002/bit.10188 11870608
34. Eliasson A Christensson C Wahlbom CF Hahn-Hägerdal B Anaerobic xylose fermentation by recombinant Saccharomyces cerevisiae carrying XYL1, XYL2, and XKS1 in mineral medium chemostat cultures Appl Environ Microbiol 2000, 66:3381-3386. 92159 10919795 10.1128/ AEM.66.8.3381-3386.2000
35. Westhuizen van der TJ Pretorius IS The value of electrophoretic fingerprinting and karyotyping in wine yeast breeding programmes Antonie Van Leeuwenhoek 1992, 61:249-257. 10.1007/BF00713932 1497329
36. Entian K-D Koetter P Yeast mutant and plasmid collections Academic Press, London, United Kingdom 1998.