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Volumn 5, Issue 7, 2008, Pages 1607-1622

Profibrotic role of myostatin in peyronie's disease

Author keywords

Fibroblasts; Fibrosis; Myofibroblasts; Penis; Stem cells; TGF 1

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; COLLAGEN; COMPLEMENTARY DNA; MYOSTATIN; SHORT HAIRPIN RNA; TRANSFORMING GROWTH FACTOR BETA1;

EID: 47949089084     PISSN: 17436095     EISSN: 17436109     Source Type: Journal    
DOI: 10.1111/j.1743-6109.2008.00847.x     Document Type: Article
Times cited : (48)

References (55)
  • 1
    • 0347129566 scopus 로고    scopus 로고
    • Sildenafil preserves intracorporeal smooth muscle after radical retropubic prostatectomy
    • Schwartz EJ, Wong P, Graydon RJ. Sildenafil preserves intracorporeal smooth muscle after radical retropubic prostatectomy. J Urol 2004; 171: 771-4.
    • (2004) J Urol , vol.171 , pp. 771-774
    • Schwartz, E.J.1    Wong, P.2    Graydon, R.J.3
  • 2
    • 17144364721 scopus 로고    scopus 로고
    • Histological alterations in cavernous tissue after radical prostatectomy
    • Iacono F, Giannella R, Somma P, Manno G, Fusco F, Mirone V. Histological alterations in cavernous tissue after radical prostatectomy. J Urol 2005; 173: 1673-6.
    • (2005) J Urol , vol.173 , pp. 1673-1676
    • Iacono, F.1    Giannella, R.2    Somma, P.3    Manno, G.4    Fusco, F.5    Mirone, V.6
  • 3
    • 33644983195 scopus 로고    scopus 로고
    • Erectile dysfunction following radical retropubic prostatectomy: Epidemiology, pathophysiology and pharmacological management
    • Nandipati KC, Raina R, Agarwal A, Zippe CD. Erectile dysfunction following radical retropubic prostatectomy: Epidemiology, pathophysiology and pharmacological management. Drugs Aging 2006; 23: 101-17.
    • (2006) Drugs Aging , vol.23 , pp. 101-117
    • Nandipati, K.C.1    Raina, R.2    Agarwal, A.3    Zippe, C.D.4
  • 4
    • 38449119700 scopus 로고    scopus 로고
    • The impact of depression, microvasculopathy, and fibrosis on development of erectile dysfunction in men with systemic sclerosis
    • Ostojic P, Damjanov N. The impact of depression, microvasculopathy, and fibrosis on development of erectile dysfunction in men with systemic sclerosis. Clin Rheumatol 2007; 26: 1671-4.
    • (2007) Clin Rheumatol , vol.26 , pp. 1671-1674
    • Ostojic, P.1    Damjanov, N.2
  • 5
    • 37349121605 scopus 로고    scopus 로고
    • Long-term continuous sildenafil treatment ameliorates corporal veno-occlusive dysfunction (CVOD) induced by cavernosal nerve resection in rats
    • [Epub ahead of print]
    • Kovanecz I, Rambhatla A, Ferrini M, Vernet D, Sanchez S, Rajfer J, Gonzalez-Cadavid N. Long-term continuous sildenafil treatment ameliorates corporal veno-occlusive dysfunction (CVOD) induced by cavernosal nerve resection in rats. Int J Impot Res 2007 [Epub ahead of print].
    • (2007) Int J Impot Res
    • Kovanecz, I.1    Rambhatla, A.2    Ferrini, M.3    Vernet, D.4    Sanchez, S.5    Rajfer, J.6    Gonzalez-Cadavid, N.7
  • 6
    • 38049100849 scopus 로고    scopus 로고
    • Molecular pharmacotherapeutic targeting of PDE5 for preservation of penile health
    • Burnett AL. Molecular pharmacotherapeutic targeting of PDE5 for preservation of penile health. J Androl 2008; 29: 3-14.
    • (2008) J Androl , vol.29 , pp. 3-14
    • Burnett, A.L.1
  • 8
    • 33845341830 scopus 로고    scopus 로고
    • Significance of fibrosis around and/or at external urinary sphincter on pelvic magnetic resonance imaging in patients with postprostatectomy incontinence
    • Tuygun C, Imamoglu A, Keyik B, Alisir I, Yorubulut M. Significance of fibrosis around and/or at external urinary sphincter on pelvic magnetic resonance imaging in patients with postprostatectomy incontinence. Urology 2006; 68: 1308-12.
    • (2006) Urology , vol.68 , pp. 1308-1312
    • Tuygun, C.1    Imamoglu, A.2    Keyik, B.3    Alisir, I.4    Yorubulut, M.5
  • 9
    • 0033256277 scopus 로고    scopus 로고
    • A multivariate analysis of lower urinary tract ageing and urinary symptoms: The role of fibrosis
    • Bercovich E, Barabino G, Pirozzi-Farina F, Deriu M. A multivariate analysis of lower urinary tract ageing and urinary symptoms: The role of fibrosis. Arch Ital Urol Androl 1999; 71: 287-92.
    • (1999) Arch Ital Urol Androl , vol.71 , pp. 287-292
    • Bercovich, E.1    Barabino, G.2    Pirozzi-Farina, F.3    Deriu, M.4
  • 10
    • 33644638349 scopus 로고    scopus 로고
    • Renal fibrosis: New insights into the pathogenesis and therapeutics
    • Liu Y. Renal fibrosis: New insights into the pathogenesis and therapeutics. Kidney Int 2006; 69: 213-7.
    • (2006) Kidney Int , vol.69 , pp. 213-217
    • Liu, Y.1
  • 11
    • 34547476097 scopus 로고    scopus 로고
    • Nitric oxide and vascular remodeling: Spotlight on the kidney
    • Eberhardt W, Pfeilschifter J. Nitric oxide and vascular remodeling: Spotlight on the kidney. Kidney Int Suppl 2007; S9-16.
    • (2007) Kidney Int , Issue.SUPPL.
    • Eberhardt, W.1    Pfeilschifter, J.2
  • 13
    • 21344457266 scopus 로고    scopus 로고
    • Mechanisms of disease: New insights into the cellular and molecular pathology of Peyronie's disease
    • Gonzalez-Cadavid NF, Rajfer J. Mechanisms of disease: New insights into the cellular and molecular pathology of Peyronie's disease. Nat Clin Pract Urol 2005; 2: 291-8.
    • (2005) Nat Clin Pract Urol , vol.2 , pp. 291-298
    • Gonzalez-Cadavid, N.F.1    Rajfer, J.2
  • 15
    • 0030794898 scopus 로고    scopus 로고
    • Peyronie's disease is associated with an increase in transforming growth factor-beta protein expression
    • El-Sakka AI, Hassoba HM, Pillarisetty RJ, Dahiya R, Lue TF. Peyronie's disease is associated with an increase in transforming growth factor-beta protein expression. J Urol 1997; 158: 1391-4.
    • (1997) J Urol , vol.158 , pp. 1391-1394
    • El-Sakka, A.I.1    Hassoba, H.M.2    Pillarisetty, R.J.3    Dahiya, R.4    Lue, T.F.5
  • 16
    • 33846573898 scopus 로고    scopus 로고
    • Fibroblast differentiation in wound healing and fibrosis
    • Darby IA, Hewitson TD. Fibroblast differentiation in wound healing and fibrosis. Int Rev Cytol 2007; 257: 143-79.
    • (2007) Int Rev Cytol , vol.257 , pp. 143-179
    • Darby, I.A.1    Hewitson, T.D.2
  • 17
    • 33847367730 scopus 로고    scopus 로고
    • Liver fibrosis: Cellular mechanisms of progression and resolution
    • Henderson NC, Iredale JP. Liver fibrosis: Cellular mechanisms of progression and resolution. Clin Sci (Lond) 2007; 112: 265-80.
    • (2007) Clin Sci (Lond) , vol.112 , pp. 265-280
    • Henderson, N.C.1    Iredale, J.P.2
  • 20
    • 0036434536 scopus 로고    scopus 로고
    • Effect of nitric oxide on the differentiation of fibroblasts into myofibroblasts in the Peyronie's disease fibrotic plaque and in its rat model
    • Vernet D, Ferrini MG, Valente EG, Magee TR, Bou-Gharios G, Rajfer J, Gonzalez-Cadavid NF. Effect of nitric oxide on the differentiation of fibroblasts into myofibroblasts in the Peyronie's disease fibrotic plaque and in its rat model. Nitric Oxide 2002; 7: 262-76.
    • (2002) Nitric Oxide , vol.7 , pp. 262-276
    • Vernet, D.1    Ferrini, M.G.2    Valente, E.G.3    Magee, T.R.4    Bou-Gharios, G.5    Rajfer, J.6    Gonzalez-Cadavid, N.F.7
  • 21
    • 33644991137 scopus 로고    scopus 로고
    • Effects of long-term vardenafil treatment on the development of fibrotic plaques in a rat model of Peyronie's disease
    • Ferrini MG, Kovanecz I, Nolazco G, Rajfer J, Gonzalez-Cadavid NF. Effects of long-term vardenafil treatment on the development of fibrotic plaques in a rat model of Peyronie's disease. BJU Int 2006; 97: 625-33.
    • (2006) BJU Int , vol.97 , pp. 625-633
    • Ferrini, M.G.1    Kovanecz, I.2    Nolazco, G.3    Rajfer, J.4    Gonzalez-Cadavid, N.F.5
  • 22
    • 1542351289 scopus 로고    scopus 로고
    • L-arginine and phosphodiesterase (PDE) inhibitors counteract fibrosis in the Peyronie's disease fibrotic plaque and related fibroblast cultures
    • Valente EG, Vernet D, Ferrini MG, Qian A, Rajfer J, Gonzalez-Cadavid NF. L-arginine and phosphodiesterase (PDE) inhibitors counteract fibrosis in the Peyronie's disease fibrotic plaque and related fibroblast cultures. Nitric Oxide 2003; 9: 229-44.
    • (2003) Nitric Oxide , vol.9 , pp. 229-244
    • Valente, E.G.1    Vernet, D.2    Ferrini, M.G.3    Qian, A.4    Rajfer, J.5    Gonzalez-Cadavid, N.F.6
  • 23
    • 17144381703 scopus 로고    scopus 로고
    • Peyronie's disease associated with increase in plasminogen activator inhibitor in fibrotic plaque
    • Davila HH, Magee TR, Zuniga FI, Rajfer J, Gonzalez-Cadavid NF. Peyronie's disease associated with increase in plasminogen activator inhibitor in fibrotic plaque. Urology 2005; 65: 645-8.
    • (2005) Urology , vol.65 , pp. 645-648
    • Davila, H.H.1    Magee, T.R.2    Zuniga, F.I.3    Rajfer, J.4    Gonzalez-Cadavid, N.F.5
  • 24
    • 0038310955 scopus 로고    scopus 로고
    • Fibrin as an inducer of fibrosis in the tunica albuginea of the rat: A new animal model of Peyronie's disease
    • Davila HH, Ferrini MG, Rajfer J, Gonzalez-Cadavid NF. Fibrin as an inducer of fibrosis in the tunica albuginea of the rat: A new animal model of Peyronie's disease. BJU Int 2003; 91: 830-8.
    • (2003) BJU Int , vol.91 , pp. 830-838
    • Davila, H.H.1    Ferrini, M.G.2    Rajfer, J.3    Gonzalez-Cadavid, N.F.4
  • 25
    • 6344243407 scopus 로고    scopus 로고
    • Gene transfer of inducible nitric oxide synthase complementary DNA regresses the fibrotic plaque in an animal model of Peyronie's disease
    • Davila HH, Magee TR, Vernet D, Rajfer J, Gonzalez-Cadavid NF. Gene transfer of inducible nitric oxide synthase complementary DNA regresses the fibrotic plaque in an animal model of Peyronie's disease. Biol Reprod 2004; 71: 1568-77.
    • (2004) Biol Reprod , vol.71 , pp. 1568-1577
    • Davila, H.H.1    Magee, T.R.2    Vernet, D.3    Rajfer, J.4    Gonzalez-Cadavid, N.F.5
  • 26
    • 3142619579 scopus 로고    scopus 로고
    • Activins, myostatin and related TGF-beta family members as novel therapeutic targets for endocrine, metabolic and immune disorders
    • Tsuchida K. Activins, myostatin and related TGF-beta family members as novel therapeutic targets for endocrine, metabolic and immune disorders. Curr Drug Targets Immune Endocr Metabol Disord 2004; 4: 157-66.
    • (2004) Curr Drug Targets Immune Endocr Metabol Disord , vol.4 , pp. 157-166
    • Tsuchida, K.1
  • 27
    • 14844337071 scopus 로고    scopus 로고
    • Transforming growth factor-beta and Smad signalling in kidney diseases
    • (Carlton)
    • Wang W, Koka V, Lan HY. Transforming growth factor-beta and Smad signalling in kidney diseases. Nephrology (Carlton) 2005; 10: 48-56.
    • (2005) Nephrology , vol.10 , pp. 48-56
    • Wang, W.1    Koka, V.2    Lan, H.Y.3
  • 28
    • 33645663734 scopus 로고    scopus 로고
    • Bone morphogenetic protein 4 mediates bile duct ligation induced liver fibrosis through activation of Smad1 and ERK1/2 in rat hepatic stellate cells
    • Fan J, Shen H, Sun Y, Li P, Burczynski F, Namaka M, Gong Y. Bone morphogenetic protein 4 mediates bile duct ligation induced liver fibrosis through activation of Smad1 and ERK1/2 in rat hepatic stellate cells. J Cell Physiol 2006; 207: 499-505.
    • (2006) J Cell Physiol , vol.207 , pp. 499-505
    • Fan, J.1    Shen, H.2    Sun, Y.3    Li, P.4    Burczynski, F.5    Namaka, M.6    Gong, Y.7
  • 30
    • 8444243360 scopus 로고    scopus 로고
    • Regulation of muscle mass by myostatin
    • Lee SJ. Regulation of muscle mass by myostatin. Annu Rev Cell Dev Biol 2004; 20: 61-86.
    • (2004) Annu Rev Cell Dev Biol , vol.20 , pp. 61-86
    • Lee, S.J.1
  • 33
    • 0036895736 scopus 로고    scopus 로고
    • Loss of myostatin attenuates severity of muscular dystrophy in mdx mice
    • Wagner KR, McPherron AC, Winik N, Lee SJ. Loss of myostatin attenuates severity of muscular dystrophy in mdx mice. Ann Neurol 2002; 52: 832-6.
    • (2002) Ann Neurol , vol.52 , pp. 832-836
    • Wagner, K.R.1    McPherron, A.C.2    Winik, N.3    Lee, S.J.4
  • 36
    • 34548492947 scopus 로고    scopus 로고
    • Relationships between transforming growth factor-beta1, myostatin, and decorin: Implications for skeletal muscle fibrosis
    • Zhu J, Li Y, Shen W, Qiao C, Ambrosio F, Lavasani M, Nozaki M, Branca MF, Huard J. Relationships between transforming growth factor-beta1, myostatin, and decorin: Implications for skeletal muscle fibrosis. J Biol Chem 2007; 282: 25852-63.
    • (2007) J Biol Chem , vol.282 , pp. 25852-25863
    • Zhu, J.1    Li, Y.2    Shen, W.3    Qiao, C.4    Ambrosio, F.5    Lavasani, M.6    Nozaki, M.7    Branca, M.F.8    Huard, J.9
  • 37
    • 39749159662 scopus 로고    scopus 로고
    • Myostatin promotes a fibrotic phenotypic switch in multipotent C3H 10T1/ 2 cells without affecting their differentiation into myofibroblasts
    • Artaza J, Singh R, Ferrini MG, Braga M, Tsao J, Gonzalez-Cadavid NF. Myostatin promotes a fibrotic phenotypic switch in multipotent C3H 10T1/ 2 cells without affecting their differentiation into myofibroblasts. J Endocrinol 2008; 196: 235-49.
    • (2008) J Endocrinol , vol.196 , pp. 235-249
    • Artaza, J.1    Singh, R.2    Ferrini, M.G.3    Braga, M.4    Tsao, J.5    Gonzalez-Cadavid, N.F.6
  • 41
    • 28144438892 scopus 로고    scopus 로고
    • Evidence that osteogenic progenitor cells in the human tunica albuginea may originate from stem cells: Implications for Peyronie's disease
    • Vernet D, Nolazco G, Cantini L, Magee TR, Qian A, Rajfer J, Gonzalez-Cadavid NF. Evidence that osteogenic progenitor cells in the human tunica albuginea may originate from stem cells: Implications for Peyronie's disease. Biol Reprod 2005; 73: 1199-210.
    • (2005) Biol Reprod , vol.73 , pp. 1199-1210
    • Vernet, D.1    Nolazco, G.2    Cantini, L.3    Magee, T.R.4    Qian, A.5    Rajfer, J.6    Gonzalez-Cadavid, N.F.7
  • 42
    • 4143098278 scopus 로고    scopus 로고
    • Comparison of gene expression profiles between Peyronie's disease and Dupuytren's contracture
    • Qian A, Meals RA, Rajfer J, Gonzalez-Cadavid NF. Comparison of gene expression profiles between Peyronie's disease and Dupuytren's contracture. Urology 2004; 64: 399-404.
    • (2004) Urology , vol.64 , pp. 399-404
    • Qian, A.1    Meals, R.A.2    Rajfer, J.3    Gonzalez-Cadavid, N.F.4
  • 44
    • 0023605130 scopus 로고
    • Mapping of gene transcripts by nuclease protection assays and cDNA primer extension
    • Calzone FJ, Britten RJ, Davidson EH. Mapping of gene transcripts by nuclease protection assays and cDNA primer extension. Methods Enzymol 1987; 152: 611-32.
    • (1987) Methods Enzymol , vol.152 , pp. 611-632
    • Calzone, F.J.1    Britten, R.J.2    Davidson, E.H.3
  • 45
    • 41849111684 scopus 로고    scopus 로고
    • Effect of muscle derived stem cells on the restoration of corpora cavernosa smooth muscle and erectile function in the aged rat
    • Feb 21; [Epub ahead of print]
    • Nolazco G, Kovanecz I, Vernet D, Ferrini M, Gelfand B, Tsao J, Magee T, Rajfer J, Gonzalez-Cadavid NF. Effect of muscle derived stem cells on the restoration of corpora cavernosa smooth muscle and erectile function in the aged rat. BJU Int 2008 Feb 21; [Epub ahead of print].
    • (2008) BJU Int
    • Nolazco, G.1    Kovanecz, I.2    Vernet, D.3    Ferrini, M.4    Gelfand, B.5    Tsao, J.6    Magee, T.7    Rajfer, J.8    Gonzalez-Cadavid, N.F.9
  • 46
    • 34547435196 scopus 로고    scopus 로고
    • Alterations in myostatin expression are associated with changes in cardiac left ventricular mass but not ejection fraction in the mouse
    • Artaza JN, Reisz-Porszasz S, Dow JS, Kloner RA, Tsao J, Bhasin S, Gonzalez-Cadavid NF. Alterations in myostatin expression are associated with changes in cardiac left ventricular mass but not ejection fraction in the mouse. J Endocrinol 2007; 194: 63-76.
    • (2007) J Endocrinol , vol.194 , pp. 63-76
    • Artaza, J.N.1    Reisz-Porszasz, S.2    Dow, J.S.3    Kloner, R.A.4    Tsao, J.5    Bhasin, S.6    Gonzalez-Cadavid, N.F.7
  • 47
    • 1242293760 scopus 로고    scopus 로고
    • Transforming growth factor-beta1 induces the differentiation of myogenic cells into fibrotic cells in injured skeletal muscle: A key event in muscle fibrogenesis
    • Li Y, Foster W, Deasy BM, Chan Y, Prisk V, Tang Y, Cummins J, Huard J. Transforming growth factor-beta1 induces the differentiation of myogenic cells into fibrotic cells in injured skeletal muscle: A key event in muscle fibrogenesis. Am J Pathol 2004; 164: 1007-19.
    • (2004) Am J Pathol , vol.164 , pp. 1007-1019
    • Li, Y.1    Foster, W.2    Deasy, B.M.3    Chan, Y.4    Prisk, V.5    Tang, Y.6    Cummins, J.7    Huard, J.8
  • 48
  • 50
    • 33746610648 scopus 로고    scopus 로고
    • Gene transfer of Smad7 modulates injury-induced conjunctival wound healing in mice
    • Yamanaka O, Ikeda K, Saika S, Miyazaki K, Ooshima A, Ohnishi Y. Gene transfer of Smad7 modulates injury-induced conjunctival wound healing in mice. Mol Vis 2006; 12: 841-51.
    • (2006) Mol Vis , vol.12 , pp. 841-851
    • Yamanaka, O.1    Ikeda, K.2    Saika, S.3    Miyazaki, K.4    Ooshima, A.5    Ohnishi, Y.6
  • 51
    • 33751104222 scopus 로고    scopus 로고
    • cAMP inhibits transforming growth factor-beta-stimulated collagen synthesis via inhibition of extracellular signal-regulated kinase 1/2 and Smad signaling in cardiac fibroblasts
    • Liu X, Sun SQ, Hassid A, Ostrom RS. cAMP inhibits transforming growth factor-beta-stimulated collagen synthesis via inhibition of extracellular signal-regulated kinase 1/2 and Smad signaling in cardiac fibroblasts. Mol Pharmacol 2006; 70: 1992-2003.
    • (2006) Mol Pharmacol , vol.70 , pp. 1992-2003
    • Liu, X.1    Sun, S.Q.2    Hassid, A.3    Ostrom, R.S.4
  • 52
    • 34848830380 scopus 로고    scopus 로고
    • Evolving concepts of liver fibrogenesis provide new diagnostic and therapeutic options
    • Gressner OA, Weiskirchen R, Gressner AM. Evolving concepts of liver fibrogenesis provide new diagnostic and therapeutic options. Comp Hepatol 2007; 6: 7.
    • (2007) Comp Hepatol , vol.6 , pp. 7
    • Gressner, O.A.1    Weiskirchen, R.2    Gressner, A.M.3
  • 53
    • 34347375050 scopus 로고    scopus 로고
    • Renal fibrosis and glomerulosclerosis in a new mouse model of diabetic nephropathy and its regression by bone morphogenic protein-7 and advanced glycation end product inhibitors
    • Sugimoto H, Grahovac G, Zeisberg M, Kalluri R. Renal fibrosis and glomerulosclerosis in a new mouse model of diabetic nephropathy and its regression by bone morphogenic protein-7 and advanced glycation end product inhibitors. Diabetes 2007; 56: 1825-33.
    • (2007) Diabetes , vol.56 , pp. 1825-1833
    • Sugimoto, H.1    Grahovac, G.2    Zeisberg, M.3    Kalluri, R.4
  • 55
    • 34248203088 scopus 로고    scopus 로고
    • The differential regulation of Smad7 in kidney tubule cells by connective tissue growth factor and transforming growth factor-beta1
    • Qi W, Chen X, Twigg S, Zhang Y, Gilbert RE, Kelly DJ, Pollock CA. The differential regulation of Smad7 in kidney tubule cells by connective tissue growth factor and transforming growth factor-beta1. Nephrology (Carlton) 2007; 12: 267-74.
    • (2007) Nephrology (Carlton) , vol.12 , pp. 267-274
    • Qi, W.1    Chen, X.2    Twigg, S.3    Zhang, Y.4    Gilbert, R.E.5    Kelly, D.J.6    Pollock, C.A.7


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