17-Beta estradiol and hydroxyestradiols interact via the NF-Kappa B pathway to elevate cyclooxygenase 2 expression and prostaglandin E2 secretion in human bronchial epithelial cells

Toxicological Sciences

Volumn 104, Issue 2, 2008, Pages 294-302

  Ho, Chia Chi ^a   Ling, Yong Chien ^a   Chang, Louis W ^b   Tsai, Hui Ti ^b   Tsai, Ming Hsien ^b   Lin, Pinpin ^a  

^a NATIONAL TSING HUA UNIVERSITY   (Taiwan)

^b NATIONAL HEALTH RESEARCH INSTITUTES   (Taiwan)

Author keywords

Endocrine; Estrogens; Nongenotoxic

Indexed keywords

ACETYLCYSTEINE; ANTIOXIDANT; BAY 117085; CYCLOOXYGENASE 2; ESTRADIOL; ESTRIOL; I KAPPA B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MESSENGER RNA; PROSTAGLANDIN E2;

ANIMAL TISSUE; ARTICLE; BRONCHUS MUCOSA; CANCER RISK; CONTROLLED STUDY; ENZYME ACTIVITY; EPIGENETICS; EPITHELIUM CELL; FEMALE; GENE EXPRESSION REGULATION; GENOTOXICITY; HUMAN; HUMAN CELL; LUNG CANCER; LUNG CARCINOGENESIS; LUNG SLICE; MOLECULAR MECHANICS; NONHUMAN; OXIDATIVE STRESS; PROSTAGLANDIN SYNTHESIS; PROTEIN FUNCTION; PROTEIN INTERACTION; PROTEIN SECRETION; RAT; TISSUE CULTURE;

ACETYLCYSTEINE; ANIMALS; BRONCHI; CYCLOOXYGENASE 2; DINOPROSTONE; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG COMBINATIONS; DRUG SYNERGISM; EPIGENESIS, GENETIC; ESTRADIOL; ESTROGENS; ESTROGENS, CATECHOL; FEMALE; HUMANS; LUNG; NF-KAPPA B; NITRILES; OXIDATIVE STRESS; RATS; RATS, SPRAGUE-DAWLEY; RESPIRATORY MUCOSA; SULFONES;

RATTUS;

EID: 47849091814     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfn096     Document Type: Article

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