Increase of carcinogenic risk via enhancement of cyclooxygenase-2 expression and hydroxyestradiol accumulation in human lung cells as a result of interaction between BaP and 17-beta estradiol

Carcinogenesis

Volumn 28, Issue 7, 2007, Pages 1606-1612

  Chang, Louis W ^a   Chang, Yun Ching ^a,b   Ho, Chia Chi ^a,b   Tsai, Ming Hsien ^a   Lin, Pinpin ^a,b  

^a NATIONAL HEALTH RESEARCH INSTITUTES   (Taiwan)

^b CHUNG SHAN MEDICAL UNIVERSITY   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

2 HYDROXYESTRADIOL; 4 HYDROXYESTRADIOL; AROMATIC HYDROCARBON RECEPTOR; BENZO[A]PYRENE; CYCLOOXYGENASE 2; CYTOCHROME P450 1A1; CYTOCHROME P450 1B1; ESTRADIOL; ESTRIOL; ESTROGEN RECEPTOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MESSENGER RNA; PROSTAGLANDIN E2;

ANIMAL TISSUE; ARTICLE; BRONCHUS MUCOSA; CANCER RISK; CARCINOGENICITY; CHEMICAL CARCINOGENESIS; CONTROLLED STUDY; ESTROGEN ACTIVITY; ESTROGEN METABOLISM; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENOTOXICITY; HUMAN; HUMAN CELL; LUNG CANCER; LUNG CARCINOGENESIS; LUNG SLICE; MALE; NONHUMAN; PRIORITY JOURNAL; PROSTAGLANDIN RELEASE; PROTEIN EXPRESSION; PROTEIN FUNCTION; RAT; REPORTER GENE; UPREGULATION;

AIR POLLUTANTS; ANIMALS; ARYL HYDROCARBON HYDROXYLASES; BENZO(A)PYRENE; BRONCHI; CARCINOGENS, ENVIRONMENTAL; CELLS, CULTURED; CYCLOOXYGENASE 2; CYTOCHROME P-450 CYP1A1; DINOPROSTONE; DRUG SYNERGISM; ENZYME ACTIVATION; EPITHELIAL CELLS; ESTRADIOL; HUMANS; LUNG; MALE; MEMBRANE PROTEINS; NF-KAPPA B; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, ESTRADIOL; UP-REGULATION;

EID: 34547749483     PISSN: 01433334     EISSN: 14602180     Source Type: Journal    
DOI: 10.1093/carcin/bgm013     Document Type: Article

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