-
1
-
-
0030003487
-
Granules in glial cells of patients with Alzheimer's disease are immunopositive for C-terminal sequences of beta-amyloid protein
-
H. Akiyama, C. Schwab, H. Kondo, H. Mori, F. Kametani, K. Ikeda and P.L. McGeer, Granules in glial cells of patients with Alzheimer's disease are immunopositive for C-terminal sequences of beta-amyloid protein, Neurosci Lett 206 (1996), 169-172.
-
(1996)
Neurosci Lett
, vol.206
, pp. 169-172
-
-
Akiyama, H.1
Schwab, C.2
Kondo, H.3
Mori, H.4
Kametani, F.5
Ikeda, K.6
McGeer, P.L.7
-
2
-
-
0034130707
-
Cell mediators of inflammation in the Alzheimer disease brain
-
H. Akiyama, T. Arai, H. Kondo, E. Tanno, C. Haga and K. Ikeda, Cell mediators of inflammation in the Alzheimer disease brain, Alzheimer Dis Assoc Disord 4 (2000), S47-S53.
-
(2000)
Alzheimer Dis Assoc Disord
, vol.4
-
-
Akiyama, H.1
Arai, T.2
Kondo, H.3
Tanno, E.4
Haga, C.5
Ikeda, K.6
-
3
-
-
1942452266
-
Specificity of mechanisms for plaque removal after A beta immunotherapy for Alzheimer disease
-
H. Akiyama and P.L. McGeer, Specificity of mechanisms for plaque removal after A beta immunotherapy for Alzheimer disease, Nat Med 10 (2004), 117-118.
-
(2004)
Nat Med
, vol.10
, pp. 117-118
-
-
Akiyama, H.1
McGeer, P.L.2
-
4
-
-
0030038809
-
Scavenging of Alzheimer's amyloid beta-protein by microglia in culture
-
M.D. Ard, G.M. Cole, J. Wei, A.P. Mehrle and J.D. Fratkin, Scavenging of Alzheimer's amyloid beta-protein by microglia in culture, J Neurosci Res 43 (1996), 190-202.
-
(1996)
J Neurosci Res
, vol.43
, pp. 190-202
-
-
Ard, M.D.1
Cole, G.M.2
Wei, J.3
Mehrle, A.P.4
Fratkin, J.D.5
-
5
-
-
0033835996
-
Peripherally administered antibodies against amyloid beta-peptide enter the central nervous system and reduce pathology in a mouse model of Alzheimer disease
-
F. Bard, C. Cannon, R. Barbour, R.L. Burke, D. Games, H. Grajeda, T. Guido, K. Hu, Huang, J. K. Johnson-Wood, K. Khan, D. Kholodenko, M. Lee, I. Lieberburg, R. Motter, M. Nguyen, F. Soriano, N. Vasquez, K. Weiss, B. Welch, P. Seubert, D. Schenk and T. Yednock, Peripherally administered antibodies against amyloid beta-peptide enter the central nervous system and reduce pathology in a mouse model of Alzheimer disease, Nat Med 6 (2000), 916-919.
-
(2000)
Nat Med
, vol.6
, pp. 916-919
-
-
Bard, F.1
Cannon, C.2
Barbour, R.3
Burke, R.L.4
Games, D.5
Grajeda, H.6
Guido, T.7
Hu, K.8
Huang9
Johnson-Wood, J.K.10
Khan, K.11
Kholodenko, D.12
Lee, M.13
Lieberburg, I.14
Motter, R.15
Nguyen, M.16
Soriano, F.17
Vasquez, N.18
Weiss, K.19
Welch, B.20
Seubert, P.21
Schenk, D.22
Yednock, T.23
more..
-
6
-
-
0030039871
-
Expression of the macrophage scavenger receptor, a multifunctional lipoprotein receptor, in microglia associated with senile plaques in Alzheimer's disease
-
R.H. Christie, M. Freeman and B.T. Hyman, Expression of the macrophage scavenger receptor, a multifunctional lipoprotein receptor, in microglia associated with senile plaques in Alzheimer's disease, Am J Pathol 148 (1996), 399-403.
-
(1996)
Am J Pathol
, vol.148
, pp. 399-403
-
-
Christie, R.H.1
Freeman, M.2
Hyman, B.T.3
-
7
-
-
0033527637
-
Uptake, degradation, and release of fibrillar and soluble forms of Alzheimer's amyloid beta-peptide by microglial cells
-
H. Chung, M.I. Brazil, T.T. Soe and F.R. Maxfield, Uptake, degradation, and release of fibrillar and soluble forms of Alzheimer's amyloid beta-peptide by microglial cells, J Biol Chem 274 (1999), 32301-32308.
-
(1999)
J Biol Chem
, vol.274
, pp. 32301-32308
-
-
Chung, H.1
Brazil, M.I.2
Soe, T.T.3
Maxfield, F.R.4
-
8
-
-
18144453796
-
Astrocytes regulate microglial phagocytosis of senile plaque cores of Alzheimer's disease
-
D.A. DeWitt, G. Perry, M. Cohen, C. Doller and J. Silver, Astrocytes regulate microglial phagocytosis of senile plaque cores of Alzheimer's disease, Exp Neurol 149 (1998), 329-340.
-
(1998)
Exp Neurol
, vol.149
, pp. 329-340
-
-
DeWitt, D.A.1
Perry, G.2
Cohen, M.3
Doller, C.4
Silver, J.5
-
9
-
-
0035696328
-
Intrahippocampal LPS injections reduce Abeta load in APP+PS1 transgenic mice
-
G. DiCarlo, D. Wilcock, D. Henderson, M. Gordon and D. Morgan, Intrahippocampal LPS injections reduce Abeta load in APP+PS1 transgenic mice, Neurobiol Aging 22 (2001), 1007-1012.
-
(2001)
Neurobiol Aging
, vol.22
, pp. 1007-1012
-
-
DiCarlo, G.1
Wilcock, D.2
Henderson, D.3
Gordon, M.4
Morgan, D.5
-
10
-
-
21444454120
-
Ineffective phagocytosis of amyloid-beta by macrophages of Alzheimer's disease patients
-
M. Fiala, J. Lin, J. Ringman, V. Kermani-Arab, G. Tsao, A. Patel, A.S. Lossinsky, M.C. Graves, A. Gustavson, J. Sayre, E. Sofroni, T. Suarez, F. Chiappelli and G. Bernard, Ineffective phagocytosis of amyloid-beta by macrophages of Alzheimer's disease patients, J Alzheimers Dis 7 (2005), 221-232.
-
(2005)
J Alzheimers Dis
, vol.7
, pp. 221-232
-
-
Fiala, M.1
Lin, J.2
Ringman, J.3
Kermani-Arab, V.4
Tsao, G.5
Patel, A.6
Lossinsky, A.S.7
Graves, M.C.8
Gustavson, A.9
Sayre, J.10
Sofroni, E.11
Suarez, T.12
Chiappelli, F.13
Bernard, G.14
-
11
-
-
0026783591
-
Ultrastructure of the microglia that phagocytose amyloid and the microglia that produce beta-amyloid fibrils
-
J. Frackowiak, H.M. Wisniewski, J. Wegiel, G.S. Merz, K. Iqbal and K.C. Wang, Ultrastructure of the microglia that phagocytose amyloid and the microglia that produce beta-amyloid fibrils, Acta Neuropathol 84 (1992), 225-233.
-
(1992)
Acta Neuropathol
, vol.84
, pp. 225-233
-
-
Frackowiak, J.1
Wisniewski, H.M.2
Wegiel, J.3
Merz, G.S.4
Iqbal, K.5
Wang, K.C.6
-
12
-
-
0037135111
-
The amyloid hypothesis of Alzheimer's disease: Progress and problems on the road to therapeutics
-
J. Hardy and D.J. Selkoe, The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics, Science 297 (2002), 353-356.
-
(2002)
Science
, vol.297
, pp. 353-356
-
-
Hardy, J.1
Selkoe, D.J.2
-
13
-
-
34247502763
-
Microglial activation is required for Abeta clearance after intracranial injection of lipopolysaccharide in APP transgenic mice
-
D.L. Herber, M. Mercer, L.M. Roth, K. Symmonds, J. Maloney, N. Wilson, M.J. Freeman, D. Morgan and M.N. Gordon, Microglial activation is required for Abeta clearance after intracranial injection of lipopolysaccharide in APP transgenic mice, J Neuroimmune Pharmacol 2 (2007), 222-231.
-
(2007)
J Neuroimmune Pharmacol
, vol.2
, pp. 222-231
-
-
Herber, D.L.1
Mercer, M.2
Roth, L.M.3
Symmonds, K.4
Maloney, J.5
Wilson, N.6
Freeman, M.J.7
Morgan, D.8
Gordon, M.N.9
-
14
-
-
0024436506
-
Relationship of microglia and astrocytes to amyloid deposits of Alzheimer disease
-
S. Itagaki, P.L. McGeer, H. Akiyama, S. Zhu and D. Selkoe, Relationship of microglia and astrocytes to amyloid deposits of Alzheimer disease, J Neuroimmunol 24 (1989), 173-182.
-
(1989)
J Neuroimmunol
, vol.24
, pp. 173-182
-
-
Itagaki, S.1
McGeer, P.L.2
Akiyama, H.3
Zhu, S.4
Selkoe, D.5
-
15
-
-
27344441173
-
Metabolism of amyloid-beta peptide and Alzheimer's disease
-
N. Iwata, M. Higuchi and T.C. Saido, Metabolism of amyloid-beta peptide and Alzheimer's disease, Pharmacol Ther 108 (2005), 129-148.
-
(2005)
Pharmacol Ther
, vol.108
, pp. 129-148
-
-
Iwata, N.1
Higuchi, M.2
Saido, T.C.3
-
16
-
-
13644255246
-
Modulation of human microglia and THP-1 cell toxicity by cytokines endogenous to the nervous system
-
A. Klegeris, C.J. Bissonnette and P.L. McGeer, Modulation of human microglia and THP-1 cell toxicity by cytokines endogenous to the nervous system, Neurobiol Aging 26 (2005), 673-682.
-
(2005)
Neurobiol Aging
, vol.26
, pp. 673-682
-
-
Klegeris, A.1
Bissonnette, C.J.2
McGeer, P.L.3
-
17
-
-
33750121865
-
Alpha-synuclein and its disease-causing mutants induce ICAM-1 and IL-6 in human astrocytes and astrocytoma cells
-
A. Klegeris, B.I. Giasson, H. Zhang, J. Maguire, S. Pelech and P.L. McGeer, Alpha-synuclein and its disease-causing mutants induce ICAM-1 and IL-6 in human astrocytes and astrocytoma cells, FASEB J 20 (2006), 2000-2008.
-
(2006)
FASEB J
, vol.20
, pp. 2000-2008
-
-
Klegeris, A.1
Giasson, B.I.2
Zhang, H.3
Maguire, J.4
Pelech, S.5
McGeer, P.L.6
-
18
-
-
3142781310
-
Apolipoprotein E promotes astrocyte colocalization and degradation of deposited amyloid-beta peptides
-
M. Koistinaho, S. Lin, X. Wu, M. Esterman, D. Koger, J. Hanson, R. Higgs, F. Liu, S. Malkani, K.R. Bales and S.M. Paul, Apolipoprotein E promotes astrocyte colocalization and degradation of deposited amyloid-beta peptides, Nat Med 10 (2004), 719-726.
-
(2004)
Nat Med
, vol.10
, pp. 719-726
-
-
Koistinaho, M.1
Lin, S.2
Wu, X.3
Esterman, M.4
Koger, D.5
Hanson, J.6
Higgs, R.7
Liu, F.8
Malkani, S.9
Bales, K.R.10
Paul, S.M.11
-
19
-
-
0023633015
-
Reactive microglia in patients with senile dementia of the Alzheimer type are positive for the histocompatibility glycoprotein HLA-DR
-
P.L. McGeer, S. Itagaki, H. Tago and E.G. McGeer, Reactive microglia in patients with senile dementia of the Alzheimer type are positive for the histocompatibility glycoprotein HLA-DR, Neurosci Lett 79 (1987), 195-200.
-
(1987)
Neurosci Lett
, vol.79
, pp. 195-200
-
-
McGeer, P.L.1
Itagaki, S.2
Tago, H.3
McGeer, E.G.4
-
20
-
-
0142012147
-
Microglial overexpression of the M-CSF receptor augments phagocytosis of opsonized Abeta
-
O.M. Mitrasinovic and G.M. Jr. Murphy, Microglial overexpression of the M-CSF receptor augments phagocytosis of opsonized Abeta, Neurobiol Aging 24 (2003), 807-815.
-
(2003)
Neurobiol Aging
, vol.24
, pp. 807-815
-
-
Mitrasinovic, O.M.1
Murphy Jr., G.M.2
-
21
-
-
24644438615
-
Dynamic complexity of the microglial activation response in transgenic models of amyloid deposition: Implications for Alzheimer therapeutics
-
D. Morgan, M.N. Gordon, J. Tan, D. Wilcock and A.M. Rojiani, Dynamic complexity of the microglial activation response in transgenic models of amyloid deposition: implications for Alzheimer therapeutics, J Neuropathol Exp Neurol 64 (2005), 743-753.
-
(2005)
J Neuropathol Exp Neurol
, vol.64
, pp. 743-753
-
-
Morgan, D.1
Gordon, M.N.2
Tan, J.3
Wilcock, D.4
Rojiani, A.M.5
-
22
-
-
33748757401
-
Regression stage senile plaques in the natural course of Alzheimer's disease
-
T. Oide, T. Kinoshita and K. Arima, Regression stage senile plaques in the natural course of Alzheimer's disease, Neuropathol Appl Neurobiol 32 (2006), 539-556.
-
(2006)
Neuropathol Appl Neurobiol
, vol.32
, pp. 539-556
-
-
Oide, T.1
Kinoshita, T.2
Arima, K.3
-
23
-
-
0030664076
-
Slow degradation of aggregates of the Alzheimer's disease amyloid beta-protein by microglial cells
-
D.M. Paresce, H. Chung and F.R. Maxfield, Slow degradation of aggregates of the Alzheimer's disease amyloid beta-protein by microglial cells, J Biol Chem 272 (1997), 29390-29397.
-
(1997)
J Biol Chem
, vol.272
, pp. 29390-29397
-
-
Paresce, D.M.1
Chung, H.2
Maxfield, F.R.3
-
24
-
-
37349114621
-
Transplanted astrocytes internalize deposited beta-amyloid peptides in a transgenic mouse model of Alzheimer's disease
-
R. Pihlaja, J. Koistinaho, T. Malm, H. Sikkila, S. Vainio and M. Koistinaho, Transplanted astrocytes internalize deposited beta-amyloid peptides in a transgenic mouse model of Alzheimer's disease, Glia 56 (2008), 154-163.
-
(2008)
Glia
, vol.56
, pp. 154-163
-
-
Pihlaja, R.1
Koistinaho, J.2
Malm, T.3
Sikkila, H.4
Vainio, S.5
Koistinaho, M.6
-
25
-
-
0028849635
-
Amyloid beta protein (A beta) removal by neuroglial cells in culture
-
L.M. Shaffer, M.D. Dority, R. Gupta-Bansal, R.C. Frederickson, S.G. Younkin and K.R. Brunden, Amyloid beta protein (A beta) removal by neuroglial cells in culture, Neurobiol Aging 16 (1995), 737-745.
-
(1995)
Neurobiol Aging
, vol.16
, pp. 737-745
-
-
Shaffer, L.M.1
Dority, M.D.2
Gupta-Bansal, R.3
Frederickson, R.C.4
Younkin, S.G.5
Brunden, K.R.6
-
26
-
-
0037394788
-
Adult mouse astrocytes degrade amyloid-beta in vitro and in situ
-
T. Wyss-Coray, J.D. Loike, T.C. Brionne, E. Lu, R. Anankov, F. Yan, S.C. Silverstein and J. Husemann, Adult mouse astrocytes degrade amyloid-beta in vitro and in situ, Nat Med 9 (2003), 453-457.
-
(2003)
Nat Med
, vol.9
, pp. 453-457
-
-
Wyss-Coray, T.1
Loike, J.D.2
Brionne, T.C.3
Lu, E.4
Anankov, R.5
Yan, F.6
Silverstein, S.C.7
Husemann, J.8
-
27
-
-
33748748708
-
Curcuminoids enhance amyloid-beta uptake by macrophages of Alzheimer's disease patients
-
L. Zhang, M. Fiala, J. Cashman, J. Sayre, A. Espinosa, M. Mahanian, J. Zaghi, V. Badmaev, M.C. Graves, G. Bernard and M, Rosenthal, Curcuminoids enhance amyloid-beta uptake by macrophages of Alzheimer's disease patients, J Alzheimers Dis 10 (2006), 1-7.
-
(2006)
J Alzheimers Dis
, vol.10
, pp. 1-7
-
-
Zhang, L.1
Fiala, M.2
Cashman, J.3
Sayre, J.4
Espinosa, A.5
Mahanian, M.6
Zaghi, J.7
Badmaev, V.8
Graves, M.C.9
Bernard, G.10
Rosenthal, M.11
|