An official ATS conference proceedings: Advances in small-animal imaging application to lung pathophysiology

Proceedings of the American Thoracic Society

Volumn 5, Issue 5, 2008, Pages 591-600

  Brown, Robert H ^a   Irvin, Charles G ^a   Allen III, Gilman B ^a   Shapiro, Steven D ^a   Martin, William J ^a   Kolb, Martin R J ^a   Hyde, Dallas M ^a   Nieman, Gary F ^a   Cody, Dianna D ^a   Ishii, Masaru ^a   Kadlecek, Stephen J ^a   Driehuys, Bastiaan ^a   Rizi, Rahim R ^a   Wu, Anna M ^a   Weber, Wolfgang A ^a   Stout, David B ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

MOLECULAR MARKER;

ACUTE LUNG INJURY; ANIMAL EXPERIMENT; ANIMAL MODEL; CHRONIC OBSTRUCTIVE LUNG DISEASE; CONFERENCE PAPER; CONTROLLED STUDY; DIAGNOSTIC IMAGING; EMPHYSEMA; EXPERIMENTAL MODEL; INTERSTITIAL LUNG DISEASE; LUNG DISEASE; MICRO POSITRON EMISSION TOMOGRAPHY; MICRO-COMPUTED TOMOGRAPHY; MICROSCOPY; MOLECULAR IMAGING; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; OPTICAL IMAGING; PATHOPHYSIOLOGY; POSITRON EMISSION TOMOGRAPHY; VIDEOMICROSCOPY;

ANIMALS; CONGRESSES AS TOPIC; DIAGNOSTIC IMAGING; DISEASE MODELS, ANIMAL; LUNG DISEASES; REPRODUCIBILITY OF RESULTS; RESPIRATION;

EID: 47749142075     PISSN: 15463222     EISSN: None     Source Type: Journal    
DOI: 10.1513/pats.200708-116ST     Document Type: Conference Paper

References (65)

1. Corry DB, Irvin CG. Promise and pitfalls in animal-based asthma research: building a better mousetrap. Immunol Res 2006;35:279-294.
2. Shore SA. Modeling airway remodeling: the winner by a nose? Am J Respir Crit Care Med 2003;168:910-911.
3. Persson CG. Con: mice are not a good model of human airway disease. Am J Respir Crit Care Med 2002;166:6-7. [Discussion, p. 8.]
4. Wenzel S, Holgate ST. The mouse trap: It still yields few answers in asthma. Am J Respir Crit Care Med 2006;174:1173-1176. [Discussion, pp. 1176-1178.]
5. Gelfand EW. Pro: mice are a good model of human airway disease. Am J Respir Crit Care Med 2002;166:5-6. [Discussion, pp. 7-8.]
6. Shapiro SD. Animal models of asthma: pro: allergic avoidance of animal (model[s]) is not anoption. Am J Respir Crit Care Med 2006;174:1171-1173.
7. Paigen K. A miracle enough: the power of mice. Nat Med 1995;1:215-220.
8. Bates JH, Irvin CG. Measuring lung function in mice: the phenotyping uncertainty principle. J Appl Physiol 2003;94:1297-1306.
9. McParland BE, Macklem PT, Pare PD. Airway wall remodeling: friend or foe? J Appl Physiol 2003;95:426-434.
10. Lundblad LK, Thompson-Figueroa J, Leclair T, Sullivan MJ, Poynter ME, Irvin CG, Bates JH. Tumor necrosis factor-alpha overexpression in lung disease: a single cause behind a complex phenotype. Am J Respir Crit Care Med 2005;171:1363-1370.
11. Tomioka S, Bates JH, Irvin CG. Airway and tissue mechanics in a murine model of asthma: alveolar capsule vs. forced oscillations. J Appl Physiol 2002;93:263-270.
12. Shapiro SD, Ingenito EP. The pathogenesis of chronic obstructive pulmonary disease: advances in the past 100 years. Am J Respir Cell Mol Biol 2005;32:367-372.
13. Mahadeva R, Shapiro SD. Chronic obstructive pulmonary disease *3: experimental animal models of pulmonary emphysema. Thorax 2002;57:908-914.
14. Brusselle GG, Bracke KR, Maes T, D'hulst AI, Moerloose KB, Joos GF, Pauwels RA. Murine models of COPD. Pulm Pharmacol Ther 2006;19:155-165.
15. Shapiro SD. Transgenic and gene-targeted mice as models for chronic obstructive pulmonary disease. Eur Respir J 2007;29:375-378.
16. Snider GL, Lucey EC, Stone PJ. Animal models of emphysema. Am Rev Respir Dis 1986;133:149-169.
17. Lee CG, Homer RJ, Zhu Z, Lanone S, Wang X, Koteliansky V, Shipley JM, Gotwals P, Noble P, Chen Q, et al. Interleukin-13 induces tissue fibrosis by selectively stimulating and activating transforming growth factor beta(1). J Exp Med 2001;194:809-821.
18. Wang Z, Zheng T, Zhu Z, Homer RJ, Riese RJ, Chapman HA Jr, Shapiro SD, Elias JA. Interferon gamma induction of pulmonary emphysema in the adult murine lung. J Exp Med 2000;192:1587-1600.
19. Fujita M, Shannon JM, Irvin CG, Fagan KA, Cool C, Augustin A, Mason RJ. Overexpression of tumor necrosis factor-alpha produces an increase in lung volumes and pulmonary hypertension. Am J Physiol Lung Cell Mol Physiol 2001;280:L39-L49.
20. Soutiere SE, Mitzner W. On defining total lung capacity in the mouse. J Appl Physiol 2004;96:1658-1664.
21. Noble PW, Homer RJ. Back to the future: historical perspective on the pathogenesis of idiopathic pulmonary fibrosis. Am J Respir Cell Mol Biol 2005;33:113-120.
22. Strieter RM. Con: inflammatory mechanisms are not a minor component of the pathogenesis of idiopathic pulmonary fibrosis. Am J Respir Crit Care Med 2002;165:1206-1207. [Discussion, pp. 1207-1208.]
23. Chua F, Gauldie J, Laurent GJ. Pulmonary fibrosis: searching for model answers. Am J Respir Cell Mol Biol 2005;33:9-13.
24. Borzone G, Moreno R, Urrea R, Meneses M, Oyarzun M, Lisboa C. Bleomycin-induced chronic lung damage does not resemble human idiopathic pulmonary fibrosis. Am J Respir Crit Care Med 2001;163:1648-1653.
25. Kolb M, Bonniaud P, Galt T, Sime PJ, Kelly MM, Margetts PJ, Gauldie J. Differences in the fibrogenic response after transfer of active transforming growth factor-beta1 gene to lungs of "fibrosis-prone" and "fibrosis-resistant" mouse strains. Am J Respir Cell Mol Biol 2002;27:141-150.
26. Bernard GR, Artigas A, Brigham KL, Carlet J, Falke K, Hudson L, Lamy M, Legall JR, Morris A, Spragg R. The American-European Consensus Conference on ARDS: definitions, mechanisms, relevant outcomes, and clinical trial coordination. Am J Respir Crit Care Med 1994;149:818-824.
27. Ware LB, Matthay MA. The acute respiratory distress syndrome. N Engl J Med 2000;342:1334-1349.
28. Zhou Z, Kozlowski J, Schuster DP. Physiologic, biochemical, and imaging characterization of acute lung injury in mice. Am J Respir Crit Care Med 2005;172:344-351.
29. Allen GB, Leclair T, Cloutier M, Thompson-Figueroa J, Bates JH. The response to recruitment worsens with progression of lung injury and fibrin accumulation in a mouse model of acid aspiration. Am J Physiol Lung Cell Mol Physiol 2007;293:L1580-L1589.
30. Neumann P, Berglund JE, Fernandez Mondejar E, Magnusson A, Hedenstierna G. Dynamics of lung collapse and recruitment during prolonged breathing in porcine lung injury. J Appl Physiol 1998;85:1533-1543.
31. Neumann P, Berglund JE, Mondejar EF, Magnusson A, Hedenstierna G. Effect of different pressure levels on the dynamics of lung collapse and recruitment in oleic-acid-induced lung injury. Am J Respir Crit Care Med 1998;158:1636-1643.
32. Allen GB, Pavone LA, DiRocco JD, Bates JH, Nieman GF. Pulmonary impedance and alveolar instability during injurious ventilation in rats. J Appl Physiol 2005;99:723-730.
33. Weibel ER, Limacher W, Bachofen H. Electron microscopy of rapidly frozen lungs: evaluation on the basis of standard criteria. J Appl Physiol 1982;53:516-527.
34. Halter JM, Steinberg JM, Schiller HJ, DaSilva M, Gatto LA, Landas S, Nieman GF. Positive end-expiratory pressure after a recruitment maneuver prevents both alveolar collapse and recruitment/derecruitment. Am J Respir Crit Care Med 2003;167:1620-1626.
35. Albert MS, Cates GD, Driehuys B, Happer W, Saam B, Springer CS Jr, Wishnia A. Biological magnetic resonance imaging using laserpolarized 129Xe. Nature 1994;370:199-201.
36. Golman K, Olsson LE, Axelsson O, Mansson S, Karlsson M, Petersson JS. Molecular imaging using hyperpolarized 13C. Br J Radiol 2003;76(Spec No 2):S118-S127.
37. Johnson GA, Cofer GP, Hedlund LW, Maronpot RR, Suddarth SA. Registered (1)H and (3)He magnetic resonance microscopy of the lung. Magn Reson Med 2001;45:365-370.
38. Deninger AJ, Mansson S, Petersson JS, Pettersson G, Magnusson P, Svensson J, Fridlund B, Hansson G, Erjefeldt I, Wollmer P, et al. Quantitative measurement of regional lung ventilation using 3He MRI. Magn Reson Med 2002;48:223-232.
39. Fischer MC, Kadlecek S, Yu J, Ishii M, Emami K, Vahdat V, Lipson DA, Rizi RR. Measurements of regional alveolar oxygen pressure using hyperpolarized 3He MRI. Acad Radiol 2005;12:1430-1439.
40. Chen XJ, Hedlund LW, Moller HE, Chawla MS, Maronpot RR, Johnson GA. Detection of emphysema in rat lungs by using magnetic resonance measurements of 3He diffusion. Proc Natl Acad Sci USA 2000;97:11478-11481.
41. Driehuys B, Cofer GP, Pollaro J, Mackel JB, Hedlund LW, Johnson GA. Imaging alveolar-capillary gas transfer using hyperpolarized 129Xe MRI. Proc Natl Acad Sci USA 2006;103:18278-18283.
42. Ruppert K, Mata JF, Brookeman JR, Hagspiel KD, Mugler JP III. Exploring lung function with hyperpolarized (129)Xe nuclear magnetic resonance. Magn Reson Med 2004;51:676-687.
43. Beckmann N, Tigani B, Ekatodramis D, Borer R, Mazzoni L, Fozard JR. Pulmonary edema induced by allergen challenge in the rat: noninvasive assessment by magnetic resonance imaging. Magn Reson Med 2001;45:88-95.
44. Gewalt SL, Glover GH, Hedlund LW, Cofer GP, MacFall JR, Johnson GA. MR microscopy of the rat lung using projection reconstruction. Magn Reson Med 1993;29:99-106.
45. Hatabu H, Gaa J, Kim D, Li W, Prasad PV, Edelman RR. Pulmonary perfusion: qualitative assessment with dynamic contrast-enhanced MRI using ultra-short TE and inversion recovery turbo FLASH. Magn Reson Med 1996;36:503-508.
46. Cody DD, Nelson CL, Bradley WM, Wislez M, Juroske D, Price RE, Zhou X, Bekele BN, Kurie JM. Murine lung tumor measurement using respiratory-gated micro-computed tomography. Invest Radiol 2005;40:263-269.
47. Cavanaugh D, Johnson E, Price RE, Kurie J, Travis EL, Cody DD. In vivo respiratory-gated micro-CT imaging in small-animal oncology models. Mol Imaging 2004;3:55-62.
48. Guerrero T, Castillo R, Sanders K, Price R, Komaki R, Cody D. Novel method to calculate pulmonary compliance images in rodents from computed tomography acquired at constant pressures. Phys Med Biol 2006;51:1101-1112.
49. Mukundan S Jr, Ghaghada KB, Badea CT, Kao CY, Hedlund LW, Provenzale JM, Johnson GA, Chen E, Bellamkonda RV, Annapragada A. A liposomal nanoscale contrast agent for preclinical CT in mice. AJR Am J Roentgenol 2006;186:300-307.
50. Kneussl MP, Richardson JB. Alpha-adrenergic receptors in human and canine tracheal and bronchial smooth muscle. J Appl Physiol 1978;45:307-311.
51. Chow PL, Stout DB, Komisopoulou E, Chatziioannou AF. A method of image registration for small animal, multi-modality imaging. Phys Med Biol 2006;51:379-390.
52. Fueger BJ, Czernin J, Hildebrandt I, Tran C, Halpern BS, Stout D, Phelps ME, Weber WA. Impact of animal handling on the results of 18F-FDG PET studies in mice. J Nucl Med 2006;47:999-1006.
53. Waldherr C, Mellinghoff IK, Tran C, Halpern BS, Rozengurt N, Safaei A, Weber WA, Stout D, Satyamurthy N, Barrio J, et al. Monitoring antiproliferative responses to kinase inhibitor therapy in mice with 3′-deoxy-3′-18F-fluorothymidine PET. J Nucl Med 2005;46:114-120.
54. Venisnik KM, Olafsen T, Loening AM, Iyer M, Gambhir SS, Wu AM. Bifunctional antibody-Renilla luciferase fusion protein for in vivo optical detection of tumors. Protein Eng Des Sel 2006;19:453-460.
55. Hildebrandt IJ, Iyer M, Wagner E, Gambhir SS. Optical imaging of transferrin targeted PEI/DNA complexes in living subjects. Gene Ther 2003;10:758-764.
56. Rice BW, Cable MD, Nelson MB. In vivo imaging of light-emitting probes. J Biomed Opt 2001;6:432-440.
57. de Boer J, van Blitterswijk C, Lowik C. Bioluminescent imaging: emerging technology for non-invasive imaging of bone tissue engineering. Biomaterials 2006;27:1851-1858.
58. Weissleder R. Molecular imaging in cancer. Science 2006;312:1168-1171.
59. Wu AM, Senter PD. Arming antibodies: prospects and challenges for immunoconjugates. Nat Biotechnol 2005;23:1137-1146.
60. Herschman HR. Molecular imaging: looking at problems, seeing solutions. Science 2003;302:605-608.
61. Blasberg RG, Tjuvajev JG. Molecular-genetic imaging: current and future perspectives. J Clin Invest 2003;111:1620-1629.
62. Gross S, Piwnica-Worms D. Real-time imaging of ligand-induced IKK activation in intact cells and in living mice. Nat Methods 2005;2:607-614.
63. Weber WA. Positron emission tomography as an imaging biomarker. J Clin Oncol 2006;24:3282-3292.
64. Schiller HJ, McCann UG 2nd, Carney DE, Gatto LA, Steinberg JM, Nieman GF. Altered alveolar mechanics in the acutely injured lung. Crit Care Med 2001;29:1049-1055.
65. 18F-fluorothymidine PET. J Nucl Med 2005;46:114-120.