Analysis of cell cycle in mouse bone marrow cells following acute in vivo exposure to56Fe ions

Journal of Radiation Research

Volumn 49, Issue 4, 2008, Pages 437-443

  Rithidech, Kanokporn Noy ^a   Golightly, Marc ^a   Whorton, Elbert ^b  

^a STONY BROOK UNIVERSITY   (United States)

^b UNIVERSITY OF TEXAS MEDICAL BRANCH   (United States)

Author keywords

56Fe ions; Cell cycle; HZE particles; in vivo; Mouse bone marrow

Indexed keywords

BONE; CELL DEATH; GAMMA RAYS; IONS; IRRADIATION; MAMMALS; STRAIN;

56FE ION; BONE MARROW; BONE MARROW CELLS; CELL CYCLE; CELL/B.E; FE-IONS; HZE PARTICLES; IN-VIVO; MOUSE BONE MARROW; MOUSE BONES;

GERMANIUM ALLOYS;

MUS;

EID: 47749116874     PISSN: 04493060     EISSN: 13499157     Source Type: Journal    
DOI: 10.1269/jrr.07109     Document Type: Article

References (21)

1. Scholz, M., Kraft-Weyrather, W., Ritter, S. and Kraft, G. (1989) Cell cycle delays induced by heavy ion irradiation of synchronous mammalian cells. Adv. Space Res. 9: 91-96.
2. Bird, R. P. and Burki, H. J. (1975) Survival of synchronized Chinese hamster cells exposed to radiation of different linear-energy transfer. Int. J Radiat. Biol. Relat. Stud. Phys. Chem. Med. 27: 105-120.
3. Ritter, S., Nasonova, E. and Gudowska-Novak, E. (2002) Effect of LET on the yield and quality of chromosomal damage in metaphase cells: a time-course study. Int. J of Radiat. Biol. 78: 191-202.
4. George, K., Wu, H., Willingham, V. and Cucinotta, F. A. (2001) The effect of space radiation on the induction of chromosome damage. Phys. Med. 17 Suppl 1: 222-225.
5. Durante, M., Furusawa, Y., George, K., Gialanella, G., Greco, O., Grossi, G., Matsufuji, N., Pugliese, M. and Yang, T. C. (1998) Rejoining and misrejoining of radiation-induced chromatin breaks. IV. Charged particles. Radiat. Res. 149: 446-454.
6. Nasonova, E. and Ritter, S. (2004) Cytogenetic effects of densely ionising radiation in human lymphocytes: impact of cell cycle delays. Cytogenet. Genome. Res. 104: 216-220.
7. Lee, R., Nasonova, E. and Ritter, S. (2005) Chromosome aberration yields and apoptosis in human lymphocytes irradiated with Fe-ions of differing LET. Adv. Space Res. 35: 268-275.
8. Ritter, S., Nasonova, E., Furusawa, Y. and Ando, K. (2002) Relationship between aberration yield and mitotic delay in human lymphocytes exposed to 200 MeV/u Fe-ions or X-rays. J. Radiat. Res. 43 Suppl: S175-179.
9. Goto, S., Watanabe, M. and Yatagai, F. (2002) Delayed cell cycle progression in human lymphoblastoid cells after exposure to high-LET radiation correlates with extremely localized DNA damage. Radiat. Res. 158: 678-686.
10. Brooks, A. L., Bao, S., Rithidech, K., Chrisler, W. B., Couch, L. A. and Braby, L. A. (2001) Induction and repair of HZE induced cytogenetic damage. Phys. Med. 17 Suppl 1: 183-184.
11. Bouffler, S. D., Breckon, G. and Cox, R. (1996) Chromosomal mechanisms in murine radiation acute myeloid leukaemogenesis. Carcinogenesis 17: 655-659.
12. Rithidech, K. N., Cronkite, E. P. and Bond, V. P. (1999) Advantages of the CBA mouse in leukemogenesis research. Blood Cells Mol. Dis. 25: 38-45.
13. Ponnaiya, B., Cornforth, M. N. and Ullrich, R. L. (1997) Radiation-induced chromosomal instability in BALB/c and C57BL/6 mice: the difference is as clear as black and white. Radiat. Res. 147: 121-125.
14. Chang, P. Y., Torous, D., Lutze-Mann, L. and Winegar, R. (2000) Impact of p53 status on heavy-ion radiation-induced micronuclei in circulating erythrocytes. Mutat. Res. 466: 87-96.
15. Tucker, J. D., Marples, B., Ramsey, M. J. and Lutze-Mann, L. H. (2004) Persistence of chromosome aberrations in mice acutely exposed to 56Fe+26 ions. Radiat. Res. 161: 648-655.
16. Tsoupas, N., Bellavia, S., Bonati, R., Brown, K., Chaing, I. H., Gardner, C. J., Jao, S., Marneris, I., A., M., Phillips, D. et al. (2004) Results from the commissioning of the NSRL beam transfer line at BNL. Proceedings of EPAC, Lucerne, Switzerland.
17. Loucas, B. D. and Cornforth, M. N. (2001) Complex chromosome exchanges induced by gamma rays in human lymphocytes: an mFISH study. Radiat Res. 155: 660-671.
18. Vermes, I., Haanen, C., Steffens-Nakken, H. and Reutellingsperger, C. (1995) A novel assay for apoptosis Flow cytometric detection of phosphatidylserine expression on early apoptotic cells using fluorescein labelled Annexin V. J of Immunol. Methods 184: 39-51.
19. Kadhim, M. A. (2003) Role of genetic background in induced instability. Oncogene, 22: 6994-6999.
20. Yasuda, H., Komiyama, T. and Fujitaka, K. (2002) Probability of cell hits in selected organs and tissues by high-LET particles at the ISS orbit. Adv. Space Res. 30: 1011-1015.
21. Vazquez, M. E. and Kirk, E. (2000) In vitro neurotoxic effects of 1 GeV/n iron particles assessed in retinal explants. Adv. Space Res. 25: 2041-2049.