Relation between COMT and aggression: A moving target?

Psychiatrie

Volumn 12, Issue 2, 2008, Pages 72-73

  Volavka, Jan ^a  

^a NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Aggression; COMT; Schizophrenia; Violence

Indexed keywords

CATECHOL METHYLTRANSFERASE;

AGGRESSION; AGGRESSIVENESS; ARTICLE; BEHAVIOR DISORDER; DISEASE SEVERITY; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; GENOTYPE; HUMAN; IMPULSIVENESS; NONHUMAN; PSYCHOLOGIC ASSESSMENT; PSYCHOSIS; SCHIZOPHRENIA; VIOLENCE;

EID: 47749087477     PISSN: 12117579     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (18)

1. Barratt ES. "Measuring and predicting aggression within the context of a personality theory." Journal of Neuropsychiatry and Clinical Neurosciences 3 (1991): S35-S39.
2. Gogos JA, Morgan M, Luine V et al. "Catechol-O-methyltransferase- deficient mice exhibit sexually dimorphic changes in catecholamine levels and behavior." Proceedings of the National Academy of Sciences of the United States of America 95 (1998): 9991-9996.
3. Han DH, Kee BS, Min KJ et al. "Effects of catechol-O- methyltransferase Val158Met polymorphism on the cognitive stability and aggression in the first-onset schizophrenic patients." Neuroreport 17 (2006): 9S-99.
4. Hare RD. "Psychopathy and antisocial personality disorder: a case of diagnostic confusion." Psychiatric Times February (1996): 39-40.
5. Hosak L, Libiger J, Cizek J et al. "The COMT Val158Met polymorphism is associated with novelty seeking in Czech methamphetamine abusers: preliminary results." Neuro.Endocrinol.Lett. 27 (2006): 799-802.
6. Kotler M, Barak P, Cohen H et al. "Homicidal behavior in schizophrenia associated with a genetic polymorphism determining low catechol O-methyltransferase (COMT) activity." Am.J.Med.Genet. 88 (1999): 628-633.
7. Lachman HM, Nolan KA, Mohr P et al. "Association between catechol O-methyltransferase genotype and violence in schizophrenia and schizoaffective disorder." American Journal of Psychiatry 155 (1998): 835-837.
8. Lachman HM, Papolos DF, Saito T et al. "Human catechol-O-methyl- transferase pharmacogenetics: description of a functional polymorphism and its potential application to neuropsychiatric disorders." Pharmacogenetics 6 (1996): 243-250.
9. Nolan, K. A., P. Czobor, B. B. Roy et al., "Characteristics of assaultive behavior among psychiatric inpatients." Psychiatr.Serv. 54 (2003): 1012-1016.
10. Nolan KA, Volavka J, Mohr P et al. "Psychopathy and violent behavior among patients with schizophrenia or schizoaffective disorder." Psychiatric Services 50 (1999): 787-792.
11. Rujescu D, Giegling I, Gietl A et al. "A functional single nucleotide polymorphism (V158M) in the COMT gene is associated with aggressive personality traits." Biol.Psychiatry 54 (2003): 34-39.
12. Strous, R. D., N. Bark, S. S. Parsia et al. "Analysis of a functional catechol O-methyltransferase gene polymorphism in schizophrenia: evidence for association with aggressive and antisocial behavior. Psychiatry Research 69 (1997): 71-77.
13. Strous RD, Nolan KA, Lapidus R et al. "Aggressive behavior in schizophrenia is associated with the low enzyme activity COMT polymorphism: A replication study." Am.J.Med.Genet. 120B (2003): 29-34.
14. Swanson JW, Van Dorn RA, Swartz MS et al. "Alternative Pathways to Violence in Persons with Schizophrenia: The Role of Childhood Antisocial Behavior Problems." Law Hum.Behav. (2007).
15. Volavka J. Neurobiology of Violence. Washington, DC: American Psychiatric Publishing, Inc., 2002.
16. Volavka J et al. COMT158 polymorphism and hostility. American Journal of Medical Genetics (Neuropsychiatric Genetics) (2004); 127B(1):28-29.
17. Yudofsky SC, Silver JM, Jackson W et al., "The Overt Aggression Scale for the objective rating of verbal and physical aggression." American Journal of Psychiatry 143 (1986): 35-39.
18. Zammit S, Jones G, Jones SJ et al. "Polymorphisms in the MAOA, MAOB, and COMT genes and aggressive behavior in schizophrenia." Am J Med.Genet.B Neuropsychiatr.Genet. 128B (2004): 19-20.