Polymorphisms in the MAOA, MAOB, and COMT genes and aggressive behavior in schizophrenia

American Journal of Medical Genetics - Neuropsychiatric Genetics

Volumn 128 B, Issue 1, 2004, Pages 19-20

  Zammit, Stanley ^a   Jones, Gaynor ^a   Jones, Susan J ^a   Norton, Nadine ^a   Sanders, Robert D ^a   Milham, Charis ^a   McCarthy, Geraldine M ^a   Jones, Lisa A ^a   Cardno, Alastair G ^a   Gray, Marion ^a   Murphy, Kieran C ^a   O'Donovan, Michael C ^a   Owen, Michael J ^a  

^a CARDIFF UNIVERSITY   (United Kingdom)

Author keywords

Aggression; Association; Catecholamines; Epistasis; Functional

Indexed keywords

AMINE OXIDASE (FLAVIN CONTAINING) ISOENZYME A; AMINE OXIDASE (FLAVIN CONTAINING) ISOENZYME B; CATECHOL METHYLTRANSFERASE;

AGGRESSION; ARTICLE; DNA POLYMORPHISM; GENE REPLICATION; GENETIC ASSOCIATION; GENETIC MODEL; GENOTYPE; HUMAN; PRIORITY JOURNAL; RISK FACTOR; SCHIZOPHRENIA; SCORING SYSTEM;

EID: 3042728651     PISSN: 15524841     EISSN: 1552485X     Source Type: Journal    
DOI: 10.1002/ajmg.b.30021     Document Type: Article

References (7)

1. Avramopoulos D, Stefanis NC, Hantoumi I, Smyrnis N, Evdokimidis I, Stefanis CN. 2002. Higher scores of self reported schizotypy in healthy young males carrying the COMT high activity allele. Mol Psychiatry 7:706-711.
2. Caspi A, McClay J, Moffitt TE, Mill J, Martin J, Craig IW, Taylor A, Poulton R. 2002. Role of genotype in cycle of violence in maltreated children. Science 297:851-854.
3. Jones G, Zammit S, Norton N, Hamshere ML, Jones SJ, Milham C, Sanders RD, McCarthy GM, Jones LA, Cardno AG, Gray M, Murphy KC, Owen MJ. 2001. Aggressive behaviour in patients with schizophrenia is associated with catechol-O- methyltransferase genotype. Br J Psychiatry 179:351-355.
4. Kotler M, Barak P, Cohen H, Averbuch IE, Grinshpoon A, Gritsenko I, Nemanov L, Ebstein RP. 1999. Homicidal behavior in schizophrenia associated with a genetic polymorphism determining low COMT activity. Am J Med Genet 88:628-633.
5. Lachman HM, Nolan KA, Mohr P, Saito T, Volavka J. 1998. Association between catechol O-methyltransferase genotype and violence in schizophrenia and schizoaffective disorder. Am J Psychiatry 155:835-837.
6. Strous RD, Bark N, Parsia SS, Volavka J, Lachman HM. 1997. Analysis of a functional catechol-O-methyltransferase gene polymorphism in schizophrenia: Evidence for association with aggressive and antisocial behavior. Psychiatry Res 69:71-77.
7. Yudofsky SC, Silver JM, Jackson W, Endicott J. 1986. The overt aggression scale for the objective rating of verbal and physical aggression. Am J Psychiatry 143:35-39.