COMT158 Polymorphism and Hostility

American Journal of Medical Genetics - Neuropsychiatric Genetics

Volumn 127 B, Issue 1, 2004, Pages 28-29

  Volavka, Jan ^a,b,i   Kennedy, James L ^c   Ni, Xingqun ^c   Czobor, Pal ^a,b   Nolan, Karen ^a,b   Sheitman, Brian ^d,e   Lindenmayer, Jean Pierre ^b,f   Citrome, Leslie ^a,b   McEvoy, Joseph ^g,h   Lieberman, Jeffrey A ^d  

^a NATHAN S KLINE INSTITUTE FOR PSYCHIATRIC RESEARCH   (United States)

^b NEW YORK UNIVERSITY   (United States)

^c UNIVERSITY OF TORONTO   (Canada)

^d UNIVERSITY OF NORTH CAROLINA   (United States)

^e Dorothea Dix Hospital   (United States)

^f MANHATTAN PSYCHIATRIC CENTER   (United States)

^g DUKE UNIVERSITY   (United States)

^h John Umstead Hospital   (United States)

ⁱ NONE   (United States)

Author keywords

Aggression; Catechol O methyltransferase; Schizoaffective disorder; Schizophrenia

Indexed keywords

CATECHOL METHYLTRANSFERASE;

ALLELE; ARTICLE; ENZYME POLYMORPHISM; HOMOZYGOSITY; HOSTILITY; HUMAN; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; SCHIZOAFFECTIVE PSYCHOSIS;

EID: 11144357073     PISSN: 15524841     EISSN: 1552485X     Source Type: Journal    
DOI: 10.1002/ajmg.b.20149     Document Type: Article

References (9)

1. Bilder R, Volavka J, Czobor P, Malhotra A, Kennedy J, Ni X, et al. 2002. Neurocognitive correlates of the COMT Val(158)Met polymorphism in chronic schizophrenia. Biol Psychiatry 52:701.
2. Citrome L, Volavka J, Czobor P, Sheitman B, Lindenmayer J-P, McEvoy J, et al. 2001. Effects of clozapine, olanzapine, risperidone, and haloperidol on hostility in treatment-resistant patients with schizophrenia and schizoaffective disorder. Psychiatric Services 52:1510-1514.
3. Jones G, Zammit S, Norton N, Hamshere ML, Jones SJ, Milham C, et al. 2001. Aggressive behaviour in patients with schizophrenia is associated with catechol-O-methyltransferase genotype. Br J Psychiatry 179:351-355.
4. Kay SR, Opler LA, Lindenmayer JP. 1988. Reliability and validity of the positive and negative syndrome scale for schizophrenics. Psychiatry Res 23:99-110.
5. Kotler M, Barak P, Cohen H, Averbuch IE, Grinshpoon A, Gritsenko I, et al. 1999. Homicidal behavior in schizophrenia associated with a genetic polymorphism determining low catechol O-methyltransferase (COMT) activity. Am J Med Genet 88:628-633.
6. Lachman HM, Nolan KA, Mohr P, Saito T, Volavka J. 1998. Association between catechol O-methyltransferase genotype and violence in schizophrenia and schizoaffective disorder. Am J Psychiatry 155:835-837.
7. Palmatier MA, Kang AM, Kidd KK. 1999. Global variation in the frequencies of functionally different catechol-O-methyltransferase alleles. Biol Psychiatry 46:557-567.
8. Strous RD, Bark N, Parsia SS, Volavka J, Lachman HM. 1997. Analysis of a functional catechol O-methyltransferase gene polymorphism in schizophrenia: Evidence for association with aggressive and antisocial behavior. Psychiatry Res 69:71-77.
9. Volavka J, Czobor P, Sheitman B, Lindenmayer J-P, Citrome L, McEvoy J, et al. 2002. Clozapine, olanzapine, risperidone, and haloperidol in treatment-resistant patients with schizophrenia and schizoaffective disorder. Am J Psychiatry 159:255-262.