Effects of plant stanol esters on serum cholesterol concentrations, relative markers of cholesterol metabolism and endothelial function in type 1 diabetes

Atherosclerosis

Volumn 199, Issue 2, 2008, Pages 432-439

  Hallikainen, Maarit ^a   Lyyra Laitinen, Tiina ^b   Laitinen, Tomi ^b   Moilanen, Leena ^b   Miettinen, Tatu A ^c   Gylling, Helena ^a,b  

^a UNIVERSITY OF EASTERN FINLAND   (Finland)

^b KUOPIO UNIVERSITY HOSPITAL   (Finland)

^c UNIVERSITY OF HELSINKI   (Finland)

Author keywords

Cholesterol; Endothelial function; Plant stanols; Plant sterols; Type 1 diabetes

Indexed keywords

BIOLOGICAL MARKER; CAMPESTEROL; CHOLESTEROL; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LOW DENSITY LIPOPROTEIN CHOLESTEROL; PHYTOSTEROL; SITOSTEROL; STANOL ESTER; TRIACYLGLYCEROL;

ADULT; ARTERY DIAMETER; ARTERY DILATATION; ARTICLE; BRACHIAL ARTERY; CHOLESTEROL BLOOD LEVEL; CHOLESTEROL METABOLISM; CLINICAL ARTICLE; CLINICAL TRIAL; CONCENTRATION RESPONSE; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CORRELATION ANALYSIS; DOUBLE BLIND PROCEDURE; DRUG EFFECT; ENDOTHELIUM; FEMALE; HUMAN; HYPOTHESIS; INSULIN DEPENDENT DIABETES MELLITUS; LIPID BLOOD LEVEL; MALE; PARALLEL DESIGN; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; TREATMENT DURATION; TRIACYLGLYCEROL BLOOD LEVEL;

ADULT; BLOOD PRESSURE; CHOLESTEROL, LDL; DIABETES MELLITUS, TYPE 1; DOUBLE-BLIND METHOD; ENDOTHELIUM; FEMALE; HUMANS; INTERVENTION STUDIES; MALE; MIDDLE AGED; PHYTOSTEROLS; SITOSTEROLS; TREATMENT OUTCOME; TRIGLYCERIDES;

EID: 47649117096     PISSN: 00219150     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.atherosclerosis.2007.10.033     Document Type: Article

References (42)

1. Roper N.A., Bilous R.W., Kelly W.F., Unwin N.C., and Connolly V.M. Cause-specific mortality in a population with diabetes: South Tees Diabetes Mortality Study. Diabetes Care 25 (2002) 43-48
2. Soedamah-Muthu S.S., Fuller J.H., Mulnier H.E., et al. High risk of cardiovascular disease in patients with type 1 diabetes in the U.K.: a cohort study using the general practice research database. Diabetes Care 29 (2006) 798-804
3. Järvisalo M., Raitakari O., Gylling H., and Miettinen T.A. Cholesterol absorption and synthesis in children with type 1 diabetes. Diabetes Care 29 (2006) 2300-2304
4. Gylling H., and Miettinen T.A. Cholesterol absorption and cholesterol and bile acid synthesis in two brothers with IDDM and diarrhea. Diabetes Care 17 (1994) 1345-1347
5. Kojima H., Hidaka H., Matsumura K., et al. Effect of glycemic control on plasma plant sterol levels and post-heparin diamine oxidase activity in type 1 diabetic patients. Atherosclerosis 145 (1999) 389-397
6. Miettinen T.A., Gylling H., Tuominen J., Simonen P., and Koivisto V. Low synthesis and high absorption of cholesterol characterize type 1 diabetes. Diabetes Care 27 (2004) 53-58
7. Gylling H., Tuominen J.A., Koivisto V.A., and Miettinen T.A. Cholesterol metabolism in type 1 diabetes. Diabetes 53 (2004) 2217-2222
8. Gylling H., Laaksonen D.E., Atalay M., et al. Markers of absorption and synthesis of cholesterol in men with type 1 diabetes. Diabetes Metab Res Rev 23 (2006) 372-377
9. Katan M.B., Grundy S.M., Jones P., et al. Efficacy and safety of plant stanols and sterols in the management of blood cholesterol levels. Mayo Clin Proc 78 (2003) 965-978
10. Gylling H., and Miettinen T.A. Serum cholesterol and cholesterol and lipoprotein metabolism in hypercholesterolaemic NIDDM patients before and during sitostanol ester-margarine treatment. Diabetologia 37 (1994) 773-780
11. Glueck C.J., Speirs J., Tracy T., et al. Relationships of serum plant sterols (phytosterols) and cholesterol in 595 hypercholesterolemic subjects, and familial aggregation of phytosterols, cholesterol, and premature coronary heart disease in hyperphytosterolemic probands and their first-degree relatives. Metabolism 40 (1991) 842-848
12. Sutherland W.H.F., Williams M.J.A., Hye E.R., et al. Association of plasma noncholesterol sterol levels with severity of coronary artery disease. Nutr Metab Cardiovasc Dis 8 (1998) 386-391
13. Sudhop T., Gottwald B.M., and von Bergmann K. Serum plant sterols as a potential risk factor for coronary heart disease. Metabolism 51 (2002) 1519-1521
14. Rajaratnam R.A., Gylling H., and Miettinen T.A. Independent association of serum squalene and noncholesterol sterols with coronary artery disease in postmenopausal women. J Am Coll Cardiol 35 (2000) 1185-1191
15. Assmann G., Cullen P., Erbey J.R., et al. Elevation in plasma sitosterol concentration is associated with an increased risk for coronary events in the PROCAM study. Circulation Suppl 108 (2003) IV-730
16. Rastas M., Seppänen R., Knuts L.-R., Karvetti R.-L., and Varo P. Nutrient composition of foods (1993), Publications of the Social Insurance Institution, Helsinki
17. Friedewald W.T., Levy R.I., and Fredrickson D.S. Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge. Clin Chem 18 (1972) 499-502
18. Miettinen T.A. Cholesterol metabolism during ketoconazole treatment in man. J Lipid Res 29 (1988) 43-51
19. Corretti M.C., Anderson T.J., Benjamin E.J., et al. Guidelines for the ultrasound assessment of endothelial-dependent flow-mediated vasodilation of the brachial artery: a report of the International Brachial Artery Reactivity Task Force. J Am Coll Cardiol 39 (2002) 257-265
20. Lyyra-Laitinen T., Vanninen J., Kiviniemi V., Vanninen E., and Laitinen T. Comparison of three edge detection methods in the analysis of brachial artery diameter from ultrasound images. Biomed Tech (Berl) Suppl 50 (2005) 1416-1417
21. Simonen P., Gylling H., and Miettinen T.A. The validity of serum squalene and non-cholesterol sterols as surrogate markers of cholesterol synthesis and absorption in type 2 diabetes. Atherosclerosis 197 (2008) 883-888
22. Simonen P.P., Gylling H.K., and Miettinen T.A. Diabetes contributes to cholesterol metabolism regardless of obesity. Diabetes Care 25 (2002) 1511-1515
23. Pihlajamäki J., Gylling H., Miettinen T.A., and Laakso M. Insulin resistance is associated with increased cholesterol synthesis and decreased cholesterol absorption in normoglycemic men. J Lipid Res 45 (2004) 507-517
24. Hallikainen M., Lyyra-Laitinen T., Laitinen T., et al. Endothelial function in hypercholesterolemic subjects: effects of plant stanol and sterol esters. Atherosclerosis 188 (2006) 425-432
25. Gylling H., Hallikainen M., Kolehmainen M., et al. Cholesterol synthesis prevails over absorption in metabolic syndrome. Transl Res: J Lab & Clin Med 149 (2007) 310-316
26. Hallikainen M., Kolehmainen M., Schwab U., et al. Serum adipokines are associated with cholesterol metabolism in the metabolic syndrome. Clin Chim Acta 383 (2007) 126-132
27. Laclaustra M., Frangi A.F., Frangi A.G., Casasnovas J.A., and Cia P. Association of endothelial function and vascular data with LDL-c and HDL-c in a homogeneous population of middle-aged, healthy military men: evidence for a critical role of optimal lipid levels. Int J Cardiol (2007). http://dx.doi.org/10.1016/j.ijcard.2007.03.001
28. Kaufmann R.L., Assal J., Soeldner J.S., et al. Plasma lipid levels in diabetic children. Effect of diet restricted in cholesterol and saturated fats. Diabetes 24 (1975) 672-679
29. Hollenbeck C.B., Connor W.E., Riddle M.C., Alaupovic P., and Leklem J.E. The effects of a high-carbohydrate low-fat cholesterol-restricted diet on plasma lipid, lipoprotein, and apoprotein concentrations in insulin-dependent (type I) diabetes mellitus. Metabolism 34 (1985) 559-566
30. Perrotti N., Santoro D., Genovese S., et al. Effect of digestible carbohydrates on glucose control in insulin-dependent diabetic patients. Diabetes Care 7 (1984) 354-359
31. Georgopoulos A., Bantle J.P., Noutsou M., Swaim W.R., and Parker S.J. Differences in the metabolism of postprandial lipoproteins after a high-monounsaturated-fat versus a high-carbohydrate diet in patients with type 1 diabetes mellitus. Arterioscler Thromb Vasc Biol 18 (1998) 773-782
32. Donaghue K.C., Pena M.M., Chan A.K., et al. Beneficial effects of increasing monounsaturated fat intake in adolescents with type 1 diabetes. Diabetes Res Clin Pract 48 (2000) 193-199
33. Strychar I., Ishac A., Rivard M., et al. Impact of a high-monounsaturated-fat diet on lipid profile in subjects with type 1 diabetes. JADA 103 (2003) 467-474
34. Ebeling P., Yki-Järvinen H., Aro A., et al. Glucose and lipid metabolism and insulin sensitivity in type 1 diabetes: the effect of guar gum. Am J Clin Nutr 48 (1988) 98-103
35. Vuorinen-Markkola H., Sinisalo M., and Koivisto V.A. Guar gum in insulin-dependent diabetes: effects on glycemic control and serum lipoproteins. Am J Clin Nutr 56 (1992) 1056-1060
36. Stephenson T.J., Setchell K.D., Kendall C.W., et al. Effect of soy protein-rich diet on renal function in young adults with insulin-dependent diabetes mellitus. Clin Nephrol 64 (2005) 1-11
37. Miettinen T.A., Klett E.L., Gylling H., Isoniemi H., and Patel S.B. Liver transplantation in a patient with sitosterolemia and cirrhosis. Gastroenterology 130 (2006) 542-547
38. Rask-Madsen C., and King G.L. Mechanisms of disease: endothelial dysfunction in insulin resistance and diabetes. Nat Clin Pract Endocrinol Metab 3 (2007) 46-56
39. Davignon J. Beneficial cardiovascular pleiotropic effects of statins. Circulation 109 (2004) 339-343
40. Ambring A., Friberg P., Axelsen M., et al. Effects of Mediterranean inspired diet on blood lipids, vascular function and oxidative stress in healthy subjects. Clin Sci 106 (2004) 519-525
41. de Jongh S., Vissers M.N., Rol P., et al. Plant sterols lower LDL cholesterol without improving endothelial function in prepubertal children with familial hypercholesterolaemia. J Inherit Metab Dis 26 (2003) 343-351
42. Law M. Plant sterol and stanol margarines and health. BMJ 320 (2000) 861-864