Psychiatric morbidity in patients with Parkinson's disease following bilateral subthalamic deep brain stimulation: Literature review

Acta Neuropsychiatrica

Volumn 20, Issue 4, 2008, Pages 182-192

  Meagher, Linton J ^a   Ilchef, Ralf ^a   Silberstein, Paul ^a   Cook, Raymond J ^a   Wasson, Daniel ^b   Malhi, Gin S ^a  

^a ROYAL NORTH SHORE HOSPITAL   (Australia)

^b North Shore Private Hospital   (Australia)

Author keywords

Deep brain stimulation; Parkinson's disease; Psychiatry; Subthalamic nucleus

Indexed keywords

ANTIDEPRESSANT AGENT;

ANXIETY DISORDER; APATHY; BRAIN DEPTH STIMULATION; DELIRIUM; DEMENTIA; DEPRESSION; DISEASE ASSOCIATION; HUMAN; HYPOMANIA; MENTAL DISEASE; MORBIDITY; PARKINSON DISEASE; REVIEW; SUBTHALAMIC NUCLEUS; SUICIDE; VISUAL HALLUCINATION;

EID: 47649104057     PISSN: 09242708     EISSN: 16015215     Source Type: Journal    
DOI: 10.1111/j.1601-5215.2008.00287.x     Document Type: Review

References (84)

1. Pollak P, Benabid AL, Gross C et al. Effects of the stimulation of the subthalamic nucleus in Parkinson's disease. Rev Neurol 1993 149 : 175 176.
2. Krack P, Batir A, Van Blercom N et al. Five-year follow-up of bilateral stimulation of the subthalamic nucleus in advanced Parkinson's disease. N Engl J Med 2003 349 : 1925 1934.
3. Rodriguez-Oroz MC, Obeso JA, Lang AE et al. Bilateral deep brain stimulation in Parkinson's disease: a multicentre study with 4 years follow-up. Brain 2005 128 : 2240 2249.
4. Kleiner-Fisman G, Herzog J, Fisman DN et al. Subthalamic nucleus deep brain stimulation: summary and meta-analysis of outcomes. Mov Disord 2006 21 (Suppl. 14 S290 S304.
5. Hilker R, Portman AT, Voges J et al. Disease progression continues in patients with advanced Parkinson's disease and effective subthalamic nucleus stimulation. J Neurol Neurosurg Psychiatry 2005 76 : 1217.
6. Pahwa R, Factor SA, Lyons KE et al. Practice parameter: treatment of Parkinson disease with motor fluctuations and dyskinesia (an evidence-based review): report of the Quality Standards Subcommittee of the American Academy of Neurology. Neurology 2006 66 : 983 995.
7. Yelnik J. Functional anatomy of the basal ganglia. Mov Disord 2002 17 (Suppl. 3 S15 S21.
8. Parent A, Hazrati LN. Functional anatomy of the basal ganglia. II. The place of subthalamic nucleus and external pallidum in basal ganglia circuitry. Brain Res Brain Res Rev 1995 20 : 128 154.
9. DeLong MR, Crutcher MD, Georgopoulos AP. Primate globus pallidus and subthalamic nucleus: functional organization. J Neurophysiol 1985 53 : 530 543.
10. Wichmann T, Bergman H, DeLong MR. The primate subthalamic nucleus. I. Functional properties in intact animals. J Neurophysiol 1994 72 : 494 506.
11. Hartmann-von Monakow, Akert K, Künzle H. Projections of the precentral motor cortex and other cortical areas of the frontal lobe to the subthalamic nucleus in the monkey. Exp Brain Res 1978 33 : 395 403.
12. Woolf NJ, Butcher LL. Cholinergic systems in the rat brain: III. Projections from the pontomesencephalic tegmentum to the thalamus, tectum, basal ganglia, and basal forebrain. Brain Res Bull 1986 16 : 603 637.
13. Sadikot AF, Parent A, Smith Y, Bolam JP. Efferent connections of the centromedian and parafascicular thalamic nuclei in the squirrel monkey: a light and electron microscopic study of the thalamostriatal projection in relation to striatal heterogeneity. J Comp Neurol 1992 320 : 228 242.
14. Mori S, Takino T, Yamada H, Sano Y. Immunohistochemical demonstration of serotonin nerve fibers in the subthalamic nucleus of the rat, cat and monkey. Neurosci Lett 1985 62 : 305 309.
15. Temel Y, Blokland A, Steinbusch HW, Visser-Vandewalle V. The functional role of the subthalamic nucleus in cognitive and limbic circuits. Prog Neurobiol 2005 76 : 393 413.
16. Perlmutter JS, Mink JW. Deep brain stimulation. Ann Rev Neurosci 2006 29 : 229 257.
17. McIntyre CC, Grill WM, Sherman DL, Thakor NV. Cellular effects of deep brain stimulation: model-based analysis of activation and inhibition. J Neurophysiol 2004 91 : 1457 1469.
18. Hashimoto T, Elder CM, Okun MS, Patrick SK, Vitek JL. Stimulation of the subthalamic nucleus changes the firing pattern of pallidal neurons. J Neurosci 2003 23 : 1916 1923.
19. Vitek JL. Mechanisms of deep brain stimulation: excitation or inhibition. Mov Disord 2002 17 (Suppl. 3 S69 S72.
20. Giovannoni G, O'Sullivan JD, Turner K, Manson AJ, Lees AJL. Hedonistic homeostatic dysregulation in patients with Parkinson's disease on dopamine replacement therapies. J Neurol Neurosurg Psychiatry 2000 68 : 423 428.
21. Brooks DJ, Piccini P. Imaging in Parkinson's disease: the role of monoamines in behaviour. Biol Psychiatry 2006 59 : 908 918.
22. Dujardin K, Blairy S, Defebvre L et al. Subthalamic nucleus stimulation induces deficits in decoding emotional facial expressions in Parkinson's disease. J Neurol Neurosurg Psychiatry 2004 75 : 202 208.
23. Kopell BH, Greenberg B, Rezai AR. Deep brain stimulation for psychiatric disorders. J Clin Neurophysiol 2004 21 : 51 67.
24. Anderson KE, Mullins J. Behavioral changes associated with deep brain stimulation surgery for Parkinson's disease. Curr Neurol Neurosci Rep 2003 3 : 306 313.
25. Mallet L, Mesnage V, Houeto JL et al. Compulsions, Parkinson's disease, and stimulation. Lancet 2002 360 : 1302 1304.
26. Malhi GS, Berk M. Does dopamine dysfunction drive depression? Acta Psychiatr Scand 2007 433 : 116 124.
27. Menza MA, Sage J, Marshall E et al. Mood changes and 'on-off' phenomena in Parkinson's disease. Mov Disord 1990 5 : 148 151.
28. Maricle RA, Nutt JG, Valentine RJ, Carter JH. Dose-response relationship of levodopa with mood and anxiety in fluctuating Parkinson's disease: a double blind, placebo-controlled study. Neurology 1995 45 : 1757 1760.
29. Ferreri F, Agbokou C, Gauthier S. Recognition and management of neuropsychiatric complications in Parkinson's disease. CMAJ 2006 175 : 1545 1552.
30. Lagopoulos J, Malhi GS, Ivanovski B, Cahill CM, Morris JGL. A matter of motion or an emotional matter? Management of depression in Parkinson's disease. Expert Rev Neurother 2005 6 : 803 810.
31. Aarsland D, Larsen JP, Lim NG et al. Range of neuropsychiatric disturbances in patients with Parkinson's disease. J Neurol Neurosurg Psychiatry 1999 67 : 492 496.
32. Woods SP, Fields JA, Troster AI. Neuropsychological sequelae of subthalamic nucleus deep brain stimulation in Parkinson's disease: a critical review. Neuropsychol Rev 2002 12 : 111 126.
33. Saint-Cyr JA, Albanese A. STN DBS in PD: selection criteria for surgery should include cognitive and psychiatric factors. Neurology 2006 66 : 1799 1800.
34. Temel Y, Kessels A, Tan S, Topdag A, Boon P, Visser-Vandewalle V. Behavioural changes after bilateral subthalamic stimulation in advanced Parkinson disease: a systematic review. Parkinsonism Relat Disord 2006 12 : 265 272.
35. Benabid AL, Chabardes S, Seigneuret E. Deep-brain stimulation in Parkinson's disease: long-term efficacy and safety - what happened this year? Curr Opin Neurol 2005 18 : 623 630.
36. Smeding HMM, Speelman JD, Koning-Haanstra M et al. Neuropsychological effects of bilateral STN stimulation in Parkinson disease: a controlled study. Neurology 2006 66 : 1830 1836.
37. Morrison CE, Borod JC, Perrine K et al. Neuropsychological functioning following bilateral subthalamic nucleus stimulation in Parkinson's disease. Arch Clin Neuropsychol 2004 19 : 165 181.
38. Castelli L, Perozzo P, Zibetti M et al. Chronic deep brain stimulation of the subthalamic nucleus for Parkinson's disease: effects on cognition, mood, anxiety and personality traits. Eur Neurol 2006 55 : 136 144.
39. Funkiewiez A, Ardouin C, Caputo E et al. Long term effects of bilateral subthalamic nucleus stimulation on cognitive function, mood, and behaviour in Parkinson's disease. J Neurol Neurosurg Psychiatry 2004 75 : 834 839.
40. De Gaspari D, Siri C, Landi A et al. Clinical and neuropsychological follow up at 12 months in patients with complicated Parkinson's disease treated with subcutaneous apomorphine infusion or deep brain stimulation of the subthalamic nucleus. J Neurol Neurosurg Psychiatry 2006 77 : 450 453.
41. Kleiner-Fisman G, Fisman DN, Sime E, Saint-Cyr JA, Lozano AM, Lang AE. Long-term follow up of bilateral deep brain stimulation of the subthalamic nucleus in patients with advanced Parkinson disease. J Neurosurg 2003 99 : 489 495.
42. Saint-Cyr JA, Trepanier LL, Kumar R et al. Neuropsychological consequences of chronic bilateral stimulation of the subthalamic nucleus in Parkinson's disease. Brain 2000 123 : 2091 2108.
43. Witt K, Pulkowski U, Herzog J et al. Deep brain stimulation of the subthalamic nucleus improves cognitive flexibility but impairs response inhibition in Parkinson disease. Arch Neurol 2004 61 : 697 700.
44. Funkiewiez A, Ardouin C, Cools R et al. Effects of levodopa and subthalamic nucleus stimulation on cognitive and affective functioning in Parkinson's disease. Mov Disord 2006 21 : 1656 1662.
45. Schroeder U, Kuehler A, Haslinger B et al. Subthalamic nucleus stimulation affects striato-anterior cingulate cortex circuit in a response conflict task: a PET study. Brain 2002 125 : 1995 2004.
46. Gaudreau JD, Gagnon P. Psychotogenic drugs and delirium pathogenesis: the central role of the thalamus. Med Hypotheses 2005 64 : 471 475.
47. Young J, Inouye SK. Delirium in older people. BMJ 2007 334 : 842 846.
48. Pandharipande P, Ely EW. Sedative and analgesic medications: risk factors for delirium and sleep disturbances in the critically ill. Crit Care Clin 2006 22 : 313 327.
49. White S, Calver BL, Newsway V et al. Enzymes of drug metabolism during delirium. Age Ageing 2005 34 : 603 608.
50. Caeiro L, Ferro JM, Claro MI, Coelho J, Albuquerque R, Figuera ML. Delirium in acute stroke: a preliminary study of the role of anticholinergic medications. Eur J Neurol 2004 11 : 699 704.
51. Krack P, Pollak P, Limousin P, Hoffmann D, Benazzouz A, Benabid AL. Inhibition of levodopa effects by internal pallidal stimulation. Mov Disord 1998 13 : 648 652.
52. Witt K, Daniels C, Herzog J et al. Differential effects of L-dopa and subthalamic stimulation on depressive symptoms and hedonic tone in Parkinson's disease. J Neuropsychiatry Clin Neurosci 2006 18 : 397 401.
53. Voon V, Saint-Cyr J, Lozano AM, Moro E, Poon YY, Lang AE. Psychiatric symptoms in patients with Parkinson disease presenting for deep brain stimulation surgery. J Neurosurg 2005 103 : 246 251.
54. Berney A, Vingerhoets F, Perrin A et al. Effect on mood of subthalamic DBS for Parkinson's disease: a consecutive series of 24 patients. Neurology 2002 59 : 1427 1429.
55. Okun MS, Green J, Saben R, Gross R, Foote KD, Vitek JL. Mood changes with deep brain stimulation of STN and GPi: results of a pilot study. J Neurol Neurosurg Psychiatry 2003 74 : 1584 1586.
56. Deuschl G, Schade-Brittinger C, Krack P et al. A randomized trial of deep-brain stimulation for Parkinson's disease. N Engl J Med 2006 355 : 896 908.
57. Voon V, Kubu C, Krack P, Houeto JL, Troster AI. Deep brain stimulation: neuropsychological and neuropsychiatric issues. Mov Disord 2006 21 (Suppl. 14 S305 S327.
58. Chou KL, Hurtig HI, Jaggi JL, Baltuch GH, Pelchat RJ, Weintraub D. Electroconvulsive therapy for depression in a Parkinson's disease patient with bilateral subthalamic nucleus deep brain stimulators. Parkinsonism Relat Disord 2005 11 : 4036.
59. Mayberg HS, Lozano AM. Penfield revisited? Understanding and modifying behavior by deep brain stimulation for PD. Neurology 2002 59 : 1298 1299.
60. Jimenez F, Velasco F, Salin-Pascual R et al. A patient with a resistant major depression disorder treated with deep brain stimulation in the inferior thalamic peduncle. Neurosurgery 2005 57 : 585 593.
61. Mayberg HS, Lozano AM, Voon V et al. Deep brain stimulation for treatment-resistant depression. Neuron 2005 45 : 651 660.
62. Voon V, Krack P, Lang A et al. Frequency and risk factors for suicidal outcomes following subthalamic deep brain stimulation for Parkinson's disease: a multicenter retrospective survey. Neurology 2006 66 (Suppl. 2 195.
63. Burkhard PR, Vingerhoets FJ, Berney A et al. Suicide after successful deep brain stimulation for movement disorders. Neurology 2004 63 : 2170.
64. Inskip H, Harris C, Barraclough B. Lifetime risk of suicide for affective disorder, alcoholism and schizophrenia. Br J Psychiatry 1998 172 : 35 37.
65. Myslobodsky M, Lalonde FM, Hicks L. Are patients with Parkinson's disease suicidal? J Geriatr Psychiatry Neurol 2001 14 : 120 124.
66. Balash Y, Merims D, Giladi N. Suicidal thoughts in patients with Parkinson's disease treated by deep brain stimulation of the subthalamic nuclei: two case reports and review of the literature. Acta Neuropsychiatr 2007 19 : 208 210.
67. Mandat TS, Hurwitz T, Honey CR. Hypomania as an adverse effect of subthalamic nucleus stimulation: report of two cases. Acta Neurochir 2006 148 : 895 897.
68. Funkiewiez A, Ardouin C, Krack P et al. Acute psychotropic effects of bilateral subthalamic nucleus stimulation and levodopa in Parkinson's disease. Mov Disord 2003 18 : 524 530.
69. Houeto JL, Mesnage V, Mallet L et al. Behavioural disorders, Parkinson's disease and subthalamic stimulation. J Neurol Neurosurg Psychiatry 2002 72 : 701 707.
70. Romito LM, Raja M, Daniele A et al. Transient mania with hypersexuality after surgery for high frequency stimulation of the subthalamic nucleus in Parkinson's disease. Mov Disord 2002 17 : 1371 1374.
71. Herzog J, Reiff J, Krack P et al. Manic episode with psychotic symptoms induced by subthalamic nucleus stimulation in a patient with Parkinson's disease. Mov Disord 2003 18 : 1382 1384.
72. Lawrence AD, Evans AH, Lees AJ. Compulsive use of dopamine replacement therapy in Parkinson's disease: reward systems gone awry? Lancet Neurol 2003 2 : 595 604.
73. Ulla M, Thobois S, Lemaire JJ et al. Manic behaviour induced by deep-brain stimulation in Parkinson's disease: evidence of substantia nigra implication? J Neurol Neurosurg Psychiatry 2006 77 : 1363 1366.
74. Daniele A, Albanese A, Contarino MF et al. Cognitive and behavioural effects of chronic stimulation of the subthalamic nucleus in patients with Parkinson's disease. J Neurol Neurosurg Psychiatry 2003 74 : 175 182.
75. Schupbach WM, Maltete D, Houeto JL et al. Neurosurgery at an earlier stage of Parkinson disease: a randomized, controlled trial. Neurology 2007 68 : 267 271.
76. Ardouin C, Voon V, Worbe Y et al. Pathological gambling in Parkinson's disease improves on chronic subthalamic nucleus stimulation. Mov Disord 2006 22 : 1941 1946.
77. Schupbach M, Gargiulo M, Welter ML et al. Neurosurgery in Parkinson disease: a distressed mind in a repaired body? Neurology 2006 66 : 1811 1816.
78. ClinicalTrials.gov [database on the internet]. U.S. National Institutes of Health. The Mood/Cognitive Effects of STN vs. GPi Deep Brain Stimulation in Parkinson's Disease [updated December 2007; cited 21 December 2007]. Available from : http://clinicaltrials.gov/ct2/show/NCT00360009.
79. Bezerra ML, Martinez JV, Nasser JA. Transient acute depression induced by high-frequency deep-brain stimulation. N Engl J Med 1999 341 : 1003.
80. Vitek JL, Bakay RA, Freeman A et al. Randomized trial of pallidotomy versus medical therapy for Parkinson's disease. Ann Neurol 2003 53 : 558 569.
81. Haldane M, Frangou S. Functional neuroimaging studies in mood disorders. Acta Neuropsychiatr 2006 18 : 88 99.
82. Lagopoulos J, Malhi GS, Ivanovski B et al. Cerebrovascular autoregulation as a neuroimaging tool. Acta Neuropsychiatr 2006 18 : 100 104.
83. Malhi GS, Lagopoulos J. Cutting edge neuropsychiatry. Acta Neuropsychiatr 2007 19 : 380 381.
84. Williams LJ, Jacka FN, Pasco JA, Dodd S, Berk M. Depression and pain: an overview. Acta Neuropsychiatr 2006 18 : 79 87.