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Volumn 159, Issue 2, 2008, Pages 267-273

Skin sensitization: Strategies for the assessment and management of risk

Author keywords

Legislation; Local lymph node assay; Risk assessment; Risk management; Skin sensitization

Indexed keywords

1 CHLORO 2,4 DINITROBENZENE; 2 BROMO 2 BROMOMETHYLGLUTARONITRILE; ALLERGEN; ANILINE; CHEMICAL AGENT; EUGENOL; PHENYLENEDIAMINE;

EID: 47549111125     PISSN: 00070963     EISSN: 13652133     Source Type: Journal    
DOI: 10.1111/j.1365-2133.2008.08625.x     Document Type: Review
Times cited : (38)

References (66)
  • 3
    • 27144479286 scopus 로고    scopus 로고
    • Hapten-protein binding: From theory to practical application in the in vitro prediction of skin sensitisation
    • Divkovic M, Pease CM, Gerberick GF, Basketter DA. Hapten-protein binding: from theory to practical application in the in vitro prediction of skin sensitisation. Contact Dermatitis 2005 53 : 189 200.
    • (2005) Contact Dermatitis , vol.53 , pp. 189-200
    • Divkovic, M.1    Pease, C.M.2    Gerberick, G.F.3    Basketter, D.A.4
  • 4
    • 84895316581 scopus 로고    scopus 로고
    • Mechanisms in allergic contact dermatitis
    • In: Frosch, P.J., Menné, T., Lepoittevin, J-P, eds4th edn. Heidelberg: Springer-Verlag
    • Rustemeyer T, Hoogstraten IMW, von Blomberg BME, Scheper RJ. Mechanisms in allergic contact dermatitis. In : Contact Dermatitis (Frosch PJ, Menné T, Lepoittevin J-P, eds 4th edn. Heidelberg : Springer-Verlag, 2006 11 44.
    • (2006) Contact Dermatitis , pp. 11-44
    • Rustemeyer, T.1    Hoogstraten, I.M.W.2    Von Blomberg, B.M.E.3    Scheper, R.J.4
  • 5
    • 0003550611 scopus 로고
    • Organization for Economic Cooperation and Development. Available at: (last accessed 21 February 2008).
    • Organization for Economic Cooperation and Development. Guidelines for Testing of Chemicals No. 406. Skin Sensitisation. 1992. Available at: http://www.oecd.org (last accessed 21 February 2008).
    • (1992) Guidelines for Testing of Chemicals No. 406. Skin Sensitisation.
  • 6
    • 0001267196 scopus 로고
    • Delayed contact hypersensitivity in the guinea pig
    • Buehler EV. Delayed contact hypersensitivity in the guinea pig. Arch Dermatol 1965 91 : 171 7.
    • (1965) Arch Dermatol , vol.91 , pp. 171-7
    • Buehler, E.V.1
  • 9
    • 0025734927 scopus 로고
    • Skin sensitization - A critical review of predictive test methods in animals and man
    • Botham PA, Basketter DA, Maurer T et al. Skin sensitization - a critical review of predictive test methods in animals and man. Food Chem Toxicol 1991 29 : 275 86.
    • (1991) Food Chem Toxicol , vol.29 , pp. 275-86
    • Botham, P.A.1    Basketter, D.A.2    Maurer, T.3
  • 10
    • 0033796803 scopus 로고    scopus 로고
    • Comparison of the sensitivities of the Buehler test and the guinea pig maximization test for predictive testing of contact allergy
    • Frankild S, Vølund A, Wahlberg JE, Andersen KE. Comparison of the sensitivities of the Buehler test and the guinea pig maximization test for predictive testing of contact allergy. Acta Derm Venereol (Stockh) 2000 80 : 256 62.
    • (2000) Acta Derm Venereol (Stockh) , vol.80 , pp. 256-62
    • Frankild, S.1    Vølund, A.2    Wahlberg, J.E.3    Andersen, K.E.4
  • 11
    • 0003188912 scopus 로고
    • Council Directive 67/548/EEC on the approximation of the laws, regulations and administrative provisions relating to the classification, packaging and labelling of dangerous substances
    • EEC
    • EEC Council Directive 67/548/EEC on the approximation of the laws, regulations and administrative provisions relating to the classification, packaging and labelling of dangerous substances. Off J Eur Commun 1967 196 : 1 98.
    • (1967) Off J Eur Commun , vol.196 , pp. 1-98
  • 12
    • 0032588393 scopus 로고    scopus 로고
    • Classification criteria for skin sensitizing chemicals: A commentary
    • Basketter DA, Flyvholm MA, Menné T. Classification criteria for skin sensitizing chemicals: a commentary. Contact Dermatitis 1999 40 : 175 82.
    • (1999) Contact Dermatitis , vol.40 , pp. 175-82
    • Basketter, D.A.1    Flyvholm, M.A.2    Menné, T.3
  • 13
    • 0026504266 scopus 로고
    • The murine local lymph node assay; Collaborative studies and new directions: A commentary
    • Kimber I, Basketter DA. The murine local lymph node assay; collaborative studies and new directions: a commentary. Food Chem Toxicol 1992 30 : 165 9.
    • (1992) Food Chem Toxicol , vol.30 , pp. 165-9
    • Kimber, I.1    Basketter, D.A.2
  • 14
    • 0027340223 scopus 로고
    • Results with OECD recommended positive control sensitizers in the maximisation, Buehler and local lymph node assays
    • Basketter DA, Selbie E, Scholes EW et al. Results with OECD recommended positive control sensitizers in the maximisation, Buehler and local lymph node assays. Food Chem Toxicol 1993 31 : 63 7.
    • (1993) Food Chem Toxicol , vol.31 , pp. 63-7
    • Basketter, D.A.1    Selbie, E.2    Scholes, E.W.3
  • 15
    • 34447334269 scopus 로고    scopus 로고
    • The local lymph node assay - A viable alternative to currently accepted skin sensitization tests
    • Basketter DA, Gerberick GF, Kimber I, Loveless SE. The local lymph node assay - a viable alternative to currently accepted skin sensitization tests. Food Chem Toxicol 1996 108 : 141 52.
    • (1996) Food Chem Toxicol , vol.108 , pp. 141-52
    • Basketter, D.A.1    Gerberick, G.F.2    Kimber, I.3    Loveless, S.E.4
  • 16
    • 0036230510 scopus 로고    scopus 로고
    • Local lymph node assay - Validation, conduct and use in practice: A commentary
    • Basketter DA, Evans P, Fielder RJ et al. Local lymph node assay - validation, conduct and use in practice: a commentary. Food Chem Toxicol 2002 40 : 593 8.
    • (2002) Food Chem Toxicol , vol.40 , pp. 593-8
    • Basketter, D.A.1    Evans, P.2    Fielder, R.J.3
  • 17
    • 0033395381 scopus 로고    scopus 로고
    • Thresholds for classification as a skin sensitiser in the local lymph node assay: A statistical evaluation
    • Basketter DA, Lea L, Cooper K et al. Thresholds for classification as a skin sensitiser in the local lymph node assay: a statistical evaluation. Food Chem Toxicol 1999 37 : 1167 74.
    • (1999) Food Chem Toxicol , vol.37 , pp. 1167-74
    • Basketter, D.A.1    Lea, L.2    Cooper, K.3
  • 18
    • 33645720142 scopus 로고    scopus 로고
    • The local lymph node assay and skin sensitisation: A cut-down screen to reduce animal requirements
    • Kimber I, Dearman RJ, Betts CJ et al. The local lymph node assay and skin sensitisation: a cut-down screen to reduce animal requirements. Contact Dermatitis 2006 54 : 181 5.
    • (2006) Contact Dermatitis , vol.54 , pp. 181-5
    • Kimber, I.1    Dearman, R.J.2    Betts, C.J.3
  • 19
    • 0030474949 scopus 로고    scopus 로고
    • The local lymph node assay: Status of validation
    • Chamberlain M, Basketter DA. The local lymph node assay: status of validation. Food Chem Toxicol 1996 34 : 999 1002.
    • (1996) Food Chem Toxicol , vol.34 , pp. 999-1002
    • Chamberlain, M.1    Basketter, D.A.2
  • 20
    • 0034011305 scopus 로고    scopus 로고
    • Local lymph node assay: Validation assessment for regulatory purposes
    • Gerberick GF, Ryan CA, Kimber I et al. Local lymph node assay: validation assessment for regulatory purposes. Am J Contact Dermat 2000 11 : 3 18.
    • (2000) Am J Contact Dermat , vol.11 , pp. 3-18
    • Gerberick, G.F.1    Ryan, C.A.2    Kimber, I.3
  • 21
    • 0035697810 scopus 로고    scopus 로고
    • ICCVAM evaluation of the murine local lymph node assay
    • II. Conclusions and recommendations of an independent scientific peer review panel.
    • Dean JH, Twerdok LE, Tice RR, Sailstad DM, Hattan DG, Stokes WS. ICCVAM evaluation of the murine local lymph node assay. II. Conclusions and recommendations of an independent scientific peer review panel. Reg Toxicol Pharmacol 2001 34 : 258 73.
    • (2001) Reg Toxicol Pharmacol , vol.34 , pp. 258-73
    • Dean, J.H.1    Twerdok, L.E.2    Tice, R.R.3    Sailstad, D.M.4    Hattan, D.G.5    Stokes, W.S.6
  • 22
    • 0000073491 scopus 로고    scopus 로고
    • Statement on the validity of the local lymph node assay for skin sensitisation testing. ECVAM Joint Research Centre, European Commission, Ispra
    • Balls M, Hellsten E. Statement on the validity of the local lymph node assay for skin sensitisation testing. ECVAM Joint Research Centre, European Commission, Ispra. Altern Lab Anim 2000 28 : 366 7.
    • (2000) Altern Lab Anim , vol.28 , pp. 366-7
    • Balls, M.1    Hellsten, E.2
  • 23
    • 0035697810 scopus 로고    scopus 로고
    • ICCVAM evaluation of the murine local lymph node assay. II. Conclusions and recommendations of an independent scientific peer review panel
    • Dean JH, Twerdok LE, Tice RR et al. ICCVAM evaluation of the murine local lymph node assay. II. Conclusions and recommendations of an independent scientific peer review panel. Regul Toxicol Pharmacol 2001 34 : 258 73.
    • (2001) Regul Toxicol Pharmacol , vol.34 , pp. 258-73
    • Dean, J.H.1    Twerdok, L.E.2    Tice, R.R.3
  • 24
    • 0028961773 scopus 로고
    • A critical commentary and updating of the guinea pig maximisation test
    • Kligman AM, Basketter DA. A critical commentary and updating of the guinea pig maximisation test. Contact Dermatitis 1995 32 : 129 34.
    • (1995) Contact Dermatitis , vol.32 , pp. 129-34
    • Kligman, A.M.1    Basketter, D.A.2
  • 25
    • 0029829578 scopus 로고    scopus 로고
    • The value and limitations of rechallenge in the guinea pig maximisation test
    • Frankild S, Basketter DA, Andersen KE. The value and limitations of rechallenge in the guinea pig maximisation test. Contact Dermatitis 1996 35 : 135 40.
    • (1996) Contact Dermatitis , vol.35 , pp. 135-40
    • Frankild, S.1    Basketter, D.A.2    Andersen, K.E.3
  • 26
    • 0021331225 scopus 로고
    • Guinea pig maximization tests with formaldehyde releasers. Results from two laboratories
    • Andersen KE, Boman A, Hamann K, Wahlberg JE. Guinea pig maximization tests with formaldehyde releasers. Results from two laboratories. Contact Dermatitis 1984 10 : 257 66.
    • (1984) Contact Dermatitis , vol.10 , pp. 257-66
    • Andersen, K.E.1    Boman, A.2    Hamann, K.3    Wahlberg, J.E.4
  • 27
    • 0029056472 scopus 로고
    • An evaluation of the suitability of benzocaine as a positive control skin sensitizer
    • Basketter DA, Scholes EW, Wahlkvist H, Montelius J. An evaluation of the suitability of benzocaine as a positive control skin sensitizer. Contact Dermatitis 1995 33 : 28 32.
    • (1995) Contact Dermatitis , vol.33 , pp. 28-32
    • Basketter, D.A.1    Scholes, E.W.2    Wahlkvist, H.3    Montelius, J.4
  • 28
    • 0001463272 scopus 로고
    • Guinea pig predictive test for contact hypersensitivity
    • In: Dean, J., Munson, A., Luster, M., Kimber, I., eds). New York: Raven Press
    • Basketter DA. Guinea pig predictive test for contact hypersensitivity. In : Immunotoxicology and Immunopharmacology (Dean J, Munson A, Luster M, Kimber I, eds). New York : Raven Press, 1994 693 702.
    • (1994) Immunotoxicology and Immunopharmacology , pp. 693-702
    • Basketter, D.A.1
  • 29
    • 0029883183 scopus 로고    scopus 로고
    • Further evaluation of the local lymph node assay in the final phase of an international collaborative trial
    • Loveless SE, Ladics GS, Gerberick GF et al. Further evaluation of the local lymph node assay in the final phase of an international collaborative trial. Toxicology 1996 108 : 141 52.
    • (1996) Toxicology , vol.108 , pp. 141-52
    • Loveless, S.E.1    Ladics, G.S.2    Gerberick, G.F.3
  • 30
    • 0032489787 scopus 로고    scopus 로고
    • Strategies for identifying false positive responses in predictive sensitisation tests
    • Basketter DA, Gerberick GF, Kimber I. Strategies for identifying false positive responses in predictive sensitisation tests. Food Chem Toxicol 1998 36 : 327 33.
    • (1998) Food Chem Toxicol , vol.36 , pp. 327-33
    • Basketter, D.A.1    Gerberick, G.F.2    Kimber, I.3
  • 31
    • 33845536212 scopus 로고    scopus 로고
    • Information derived from sensitisation test methods: Test sensitivity, false positives and false negatives
    • Basketter DA, Kimber I. Information derived from sensitisation test methods: test sensitivity, false positives and false negatives. Contact Dermatitis 2007 56 : 1 4.
    • (2007) Contact Dermatitis , vol.56 , pp. 1-4
    • Basketter, D.A.1    Kimber, I.2
  • 32
    • 33749561246 scopus 로고    scopus 로고
    • Identification and classification of skin sensitisers: Identifying false positives and false negatives
    • Basketter DA, McFadden J, Evans P et al. Identification and classification of skin sensitisers: identifying false positives and false negatives. Contact Dermatitis 2006 55 : 268 73.
    • (2006) Contact Dermatitis , vol.55 , pp. 268-73
    • Basketter, D.A.1    McFadden, J.2    Evans, P.3
  • 34
    • 0033497170 scopus 로고    scopus 로고
    • Chemical allergy: Estimation of potency, thresholds and risk assessments
    • Basketter DA, Evans P, Gerberick GF, Kimber I. Chemical allergy: estimation of potency, thresholds and risk assessments. Comments Toxicol 2000 7 : 79 89.
    • (2000) Comments Toxicol , vol.7 , pp. 79-89
    • Basketter, D.A.1    Evans, P.2    Gerberick, G.F.3    Kimber, I.4
  • 35
  • 36
    • 34347386417 scopus 로고    scopus 로고
    • Extrapolating local lymph node assay EC3 values to estimate relative sensitizing potency
    • Ryan CA, Chaney JG, Gerberick GF et al. Extrapolating local lymph node assay EC3 values to estimate relative sensitizing potency. Cutan Ocul Toxicol 2007 26 : 135 45.
    • (2007) Cutan Ocul Toxicol , vol.26 , pp. 135-45
    • Ryan, C.A.1    Chaney, J.G.2    Gerberick, G.F.3
  • 37
    • 30144443263 scopus 로고    scopus 로고
    • Compilation of historical local lymph node assay data for evaluation of skin sensitization alternative methods
    • Gerberick GF, Ryan CA, Kern PS. Compilation of historical local lymph node assay data for evaluation of skin sensitization alternative methods. Dermatitis 2005 16 : 157 202.
    • (2005) Dermatitis , vol.16 , pp. 157-202
    • Gerberick, G.F.1    Ryan, C.A.2    Kern, P.S.3
  • 38
    • 34447579161 scopus 로고    scopus 로고
    • Evaluation of the contact and respiratory sensitization potential of volatile organic compounds generated by simulated indoor air chemistry
    • Anderson SE, Wells J, Fedorowicz A. Evaluation of the contact and respiratory sensitization potential of volatile organic compounds generated by simulated indoor air chemistry. Toxicol Sci 2007 97 : 355 63.
    • (2007) Toxicol Sci , vol.97 , pp. 355-63
    • Anderson, S.E.1    Wells, J.2    Fedorowicz, A.3
  • 39
    • 0036208896 scopus 로고    scopus 로고
    • Ranking of allergenic potency of rubber chemicals in a modified local lymph node assay
    • de Jong WH, van Och FM, den Hartog Jager CF. Ranking of allergenic potency of rubber chemicals in a modified local lymph node assay. Toxicol Sci 2002 66 : 226 32.
    • (2002) Toxicol Sci , vol.66 , pp. 226-32
    • De Jong, W.H.1    Van Och, F.M.2    Den Hartog Jager, C.F.3
  • 40
    • 21744432479 scopus 로고    scopus 로고
    • Contact sensitization: A new approach to risk assessment
    • Kimber I, Basketter DA. Contact sensitization: a new approach to risk assessment. Human Ecol Risk Assess 1997 3 : 385 95.
    • (1997) Human Ecol Risk Assess , vol.3 , pp. 385-95
    • Kimber, I.1    Basketter, D.A.2
  • 41
    • 0034111053 scopus 로고    scopus 로고
    • Use of the local lymph node assay for the estimation of relative contact allergenic potency
    • Basketter DA, Blaikie L, Dearman RJ. Use of the local lymph node assay for the estimation of relative contact allergenic potency. Contact Dermatitis 2000 42 : 344 8.
    • (2000) Contact Dermatitis , vol.42 , pp. 344-8
    • Basketter, D.A.1    Blaikie, L.2    Dearman, R.J.3
  • 42
    • 0034820655 scopus 로고    scopus 로고
    • Contact allergenic potency: Correlation of human and local lymph node assay data
    • Gerberick GF, Robinson MK, Ryan CA. Contact allergenic potency: correlation of human and local lymph node assay data. Am J Contact Dermat 2001 12 : 156 61.
    • (2001) Am J Contact Dermat , vol.12 , pp. 156-61
    • Gerberick, G.F.1    Robinson, M.K.2    Ryan, C.A.3
  • 43
    • 14344251179 scopus 로고    scopus 로고
    • Evaluation of the skin sensitising potency of chemicals using existing methods and considerations of relevance for elicitation
    • Basketter DA, Andersen KE, Lidén C. Evaluation of the skin sensitising potency of chemicals using existing methods and considerations of relevance for elicitation. Contact Dermatitis 2005 52 : 39 43.
    • (2005) Contact Dermatitis , vol.52 , pp. 39-43
    • Basketter, D.A.1    Andersen, K.E.2    Lidén, C.3
  • 44
    • 17744396114 scopus 로고    scopus 로고
    • Skin sensitization testing in potency and risk assessment
    • Kimber I, Basketter DA, Berthold K. Skin sensitization testing in potency and risk assessment. Toxicol Sci 2001 59 : 198 208.
    • (2001) Toxicol Sci , vol.59 , pp. 198-208
    • Kimber, I.1    Basketter, D.A.2    Berthold, K.3
  • 47
    • 0021082057 scopus 로고
    • Kathon biocide: Manifestation of delayed contact dermatitis in guinea pigs is dependent on the concentration for induction and challenge
    • Chan PD, Baldwin RC, Parson RD. Kathon biocide: manifestation of delayed contact dermatitis in guinea pigs is dependent on the concentration for induction and challenge. J Invest Dermatol 1983 81 : 409 11.
    • (1983) J Invest Dermatol , vol.81 , pp. 409-11
    • Chan, P.D.1    Baldwin, R.C.2    Parson, R.D.3
  • 48
    • 0021960353 scopus 로고
    • Dose response assessments of Kathon biocide. I. Diagnostic use and diagnostic threshold patch testing with sensitised humans
    • Weaver JE, Carding CW, Maibach HI. Dose response assessments of Kathon biocide. I. Diagnostic use and diagnostic threshold patch testing with sensitised humans. Contact Dermatitis 1985 12 : 141 5.
    • (1985) Contact Dermatitis , vol.12 , pp. 141-5
    • Weaver, J.E.1    Carding, C.W.2    Maibach, H.I.3
  • 49
    • 0001631716 scopus 로고
    • Methylisothiazolinone/methylchloroisothiazolinone (Kathon CG) allergy: An updated review
    • de Groot AC. Methylisothiazolinone/methylchloroisothiazolinone (Kathon CG) allergy: an updated review. Am J Contact Dermat 1990 1 : 151 6.
    • (1990) Am J Contact Dermat , vol.1 , pp. 151-6
    • De Groot, A.C.1
  • 50
    • 0035688475 scopus 로고    scopus 로고
    • Understanding fragrance allergy using an exposure-based risk assessment approach
    • Gerberick GF, Robinson MK, Felter S. Understanding fragrance allergy using an exposure-based risk assessment approach. Contact Dermatitis 2001 45 : 333 40.
    • (2001) Contact Dermatitis , vol.45 , pp. 333-40
    • Gerberick, G.F.1    Robinson, M.K.2    Felter, S.3
  • 51
    • 0036877375 scopus 로고    scopus 로고
    • A review of the scientific basis for default uncertainty factors for use in quantitative risk assessment of the induction of allergic contact dermatitis
    • Felter SP, Robinson MK, Basketter DA, Gerberick GF. A review of the scientific basis for default uncertainty factors for use in quantitative risk assessment of the induction of allergic contact dermatitis. Contact Dermatitis 2002 47 : 257 66.
    • (2002) Contact Dermatitis , vol.47 , pp. 257-66
    • Felter, S.P.1    Robinson, M.K.2    Basketter, D.A.3    Gerberick, G.F.4
  • 52
    • 0037299775 scopus 로고    scopus 로고
    • Application of the risk assessment paradigm to the induction of allergic contact dermatitis
    • Felter SP, Ryan CA, Basketter DA, Gerberick GF. Application of the risk assessment paradigm to the induction of allergic contact dermatitis. Regul Toxicol Pharmacol 2003 37 : 1 10.
    • (2003) Regul Toxicol Pharmacol , vol.37 , pp. 1-10
    • Felter, S.P.1    Ryan, C.A.2    Basketter, D.A.3    Gerberick, G.F.4
  • 53
    • 33745598819 scopus 로고    scopus 로고
    • Fragrance allergy: Assessing the risk from fabric washing products
    • Corea N, Basketter DA, van Asten A et al. Fragrance allergy: assessing the risk from fabric washing products. Contact Dermatitis 2006 55 : 48 53.
    • (2006) Contact Dermatitis , vol.55 , pp. 48-53
    • Corea, N.1    Basketter, D.A.2    Van Asten, A.3
  • 54
    • 47549087254 scopus 로고    scopus 로고
    • Dermal sensitization quantitative risk assessment (QRA) for fragrance ingredients
    • in press.
    • Api AM, Basketter DA, Cadby PA et al. Dermal sensitization quantitative risk assessment (QRA) for fragrance ingredients. Regul Toxicol Pharmacol 2008 in press.
    • (2008) Regul Toxicol Pharmacol
    • Api, A.M.1    Basketter, D.A.2    Cadby, P.A.3
  • 55
    • 0033942851 scopus 로고    scopus 로고
    • Activity of human contact allergens in the murine local lymph node assay
    • Ryan CA, Gerberick GF, Cruse LW et al. Activity of human contact allergens in the murine local lymph node assay. Contact Dermatitis 2000 43 : 95 102.
    • (2000) Contact Dermatitis , vol.43 , pp. 95-102
    • Ryan, C.A.1    Gerberick, G.F.2    Cruse, L.W.3
  • 56
    • 0242456077 scopus 로고    scopus 로고
    • Proposal for a risk assessment methodology for skin sensitization based on sensitization potency data
    • Griem P, Goebel C, Scheffler H. Proposal for a risk assessment methodology for skin sensitization based on sensitization potency data. Regul Toxicol Pharmacol 2003 38 : 269 90.
    • (2003) Regul Toxicol Pharmacol , vol.38 , pp. 269-90
    • Griem, P.1    Goebel, C.2    Scheffler, H.3
  • 57
    • 1842835106 scopus 로고    scopus 로고
    • Quantitative relationship between the local lymph node assay and human skin sensitization assays
    • Schneider K, Akkan Z. Quantitative relationship between the local lymph node assay and human skin sensitization assays. Regul Toxicol Pharmacol 2004 39 : 245 55.
    • (2004) Regul Toxicol Pharmacol , vol.39 , pp. 245-55
    • Schneider, K.1    Akkan, Z.2
  • 58
    • 28344443390 scopus 로고    scopus 로고
    • Predictive identification of human skin sensitisation thresholds
    • Basketter DA, Clapp C, Jefferies D et al. Predictive identification of human skin sensitisation thresholds. Contact Dermatitis 2005 53 : 260 67.
    • (2005) Contact Dermatitis , vol.53 , pp. 260-67
    • Basketter, D.A.1    Clapp, C.2    Jefferies, D.3
  • 59
    • 0038521286 scopus 로고    scopus 로고
    • Methyldibromo glutaronitrile: Clinical experience and exposure-based risk assessment
    • Zachariae C, Rastogi S, Devantier C et al. Methyldibromo glutaronitrile: clinical experience and exposure-based risk assessment. Contact Dermatitis 2003 48 : 150 4.
    • (2003) Contact Dermatitis , vol.48 , pp. 150-4
    • Zachariae, C.1    Rastogi, S.2    Devantier, C.3
  • 61
    • 0346013616 scopus 로고
    • Nickel Directive: European Parliament and Council Directive 94/27/EC of 30 June 1994 amending for the 12th time Directive 76/769/EEC on the approximation of the laws, regulations and administrative provisions of the Member States relating to restrictions on the marketing and use of certain dangerous substances and preparations
    • 22 July. P
    • Nickel Directive: European Parliament and Council Directive 94/27/EC of 30 June 1994 amending for the 12th time Directive 76/769/EEC on the approximation of the laws, regulations and administrative provisions of the Member States relating to restrictions on the marketing and use of certain dangerous substances and preparations. Off J Eur Commun L 188, 22 July 1994, P 0001 0002.
    • (1994) Off J Eur Commun L , vol.188 , pp. 0001-0002
  • 62
    • 31444445122 scopus 로고    scopus 로고
    • Cement Directive: European Parliament and Council Directive 2003/53/EC of 18 June 2003 amending for the 26th time Directive 76/769/EEC relating to restrictions on the marketing and use of certain dangerous substances and preparations (nonylphenol, nonylphenol ethoxylate and cement)
    • Cement Directive: European Parliament and Council Directive 2003/53/EC of 18 June 2003 amending for the 26th time Directive 76/769/EEC relating to restrictions on the marketing and use of certain dangerous substances and preparations (nonylphenol, nonylphenol ethoxylate and cement). Off J Eur Commun L 2003 178 : 24 7.
    • (2003) Off J Eur Commun L , vol.178 , pp. 24-7
  • 63
    • 34250629329 scopus 로고    scopus 로고
    • Sensitization to 26 fragrances to be labelled according to current European regulation
    • Schnuch A, Uter W, Geier J et al. Sensitization to 26 fragrances to be labelled according to current European regulation. Contact Dermatitis 2007 57 : 1 10.
    • (2007) Contact Dermatitis , vol.57 , pp. 1-10
    • Schnuch, A.1    Uter, W.2    Geier, J.3
  • 64
    • 36349036534 scopus 로고    scopus 로고
    • A general population from Thailand: Incidence of common allergens with emphasis on para-phenylenediamine
    • White JML, Gilmour NJ, Jefferies D et al. A general population from Thailand: incidence of common allergens with emphasis on para-phenylenediamine. Clin Exp Allergy 2007 37 : 1848 53.
    • (2007) Clin Exp Allergy , vol.37 , pp. 1848-53
    • White, J.M.L.1    Gilmour, N.J.2    Jefferies, D.3
  • 65
    • 2442680114 scopus 로고    scopus 로고
    • Contact allergy to fragrances: Frequencies of sensitization from 1996 to 2002. Results of the IVDK
    • Schnuch A, Lessmann H, Geier J et al. Contact allergy to fragrances: frequencies of sensitization from 1996 to 2002. Results of the IVDK. Contact Dermatitis 2004 50 : 65 76.
    • (2004) Contact Dermatitis , vol.50 , pp. 65-76
    • Schnuch, A.1    Lessmann, H.2    Geier, J.3


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