The local lymph node assay and skin sensitization: A cut-down screen to reduce animal requirements?

Contact Dermatitis

Volumn 54, Issue 4, 2006, Pages 181-185

  Kimber, Ian ^a   Dearman, Rebecca J ^a   Betts, Catherine J ^a   Gerberick, G Frank ^b   Ryan, Cindy A ^b   Kern, Petra S ^b   Patlewicz, Grace Y ^c   Basketter, David A ^d  

^a JEALOTT S HILL INTERNATIONAL RESEARCH CENTRE   (United Kingdom)

^b PROCTER AND GAMBLE COMPANY   (United States)

^c JOINT RESEARCH CENTRE   (Italy)

^d UNILEVER RESEARCH   (United Kingdom)

Author keywords

Hazard identification; Local lymph node assay; Skin sensitization screening

Indexed keywords

2 PROPANOL; ABIETIC ACID; CAMPHORQUINONE; CHEMICAL COMPOUND; CLOTRIMAZOLE; DODECYL GALLATE; ISOEUGENOL; LACTIC ACID; OXAZOLONE; THIAZOLE DERIVATIVE;

ANIMAL CARE; ANIMAL EXPERIMENT; ANIMAL WELFARE; ARTICLE; CONTROLLED STUDY; DATA BASE; FEMALE; LOCAL LYMPH NODE ASSAY; MOUSE; NONHUMAN; SCREENING; SKIN SENSITIZATION;

ANIMAL TESTING ALTERNATIVES; ANIMALS; DATABASES, FACTUAL; DERMATITIS, ALLERGIC CONTACT; DRUG HYPERSENSITIVITY; FEMALE; LOCAL LYMPH NODE ASSAY; MICE; MICE, INBRED CBA; TOXICITY TESTS;

EID: 33645720142     PISSN: 01051873     EISSN: 16000536     Source Type: Journal    
DOI: 10.1111/j.0105-1873.2006.00827.x     Document Type: Article

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