Poorly reactive 5-piperazin-1-yl-1,3,4-thiadiazol-2-amines rendered as valid substrates for Groebke-Blackburn type multi-component reaction with aldehydes and isocyanides using TMSCl as a promoter

Tetrahedron Letters

Volumn 49, Issue 36, 2008, Pages 5241-5243

  Krasavin, Mikhail ^a,b   Tsirulnikov, Sergey ^a   Nikulnikov, Mikhail ^a   Kysil, Volodymyr ^c   Ivachtchenko, Alexandre ^c  

^a Chemical Diversity Research Institute   (Russian Federation)

^b TULA STATE LEV TOLSTOY PEDAGOGICAL UNIVERSITY   (Russian Federation)

^c CHEMDIV INC   (United States)

Author keywords

2 Aminoazoles; Groebke Blackburn type reactions; Isocyanide based multi component reactions; Lewis acid promoted MCR; Trimethylchlorosilane

Indexed keywords

5 PIPERAZIN 1 YL 1,3,4 THIADIAZOL 2 AMINE DERIVATIVE; ALDEHYDE; AMINE; LEWIS ACID; PYRROLE;

ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CHEMICAL REACTION; FILTRATION; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; PROTON NUCLEAR MAGNETIC RESONANCE;

EID: 47549094819     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tetlet.2008.06.113     Document Type: Article

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