TMSCl-promoted isocyanide-based MCR of ethylenediamines: an efficient assembling of 2-aminopyrazine core

Tetrahedron Letters

Volumn 48, Issue 36, 2007, Pages 6239-6244

  Kysil, Volodymyr ^a   Tkachenko, Sergey ^a   Khvat, Alexander ^a   Williams, Caroline ^a   Tsirulnikov, Sergey ^b   Churakova, Marina ^b   Ivachtchenko, Alexandre ^a  

^a CHEMDIV INC   (United States)

^b Chemical Diversity Research Institute   (Russian Federation)

Author keywords

Aminopyrazine; Isocyanide; Multicomponent reaction (MCR); Pyrazine ring synthesis; Trimethylchlorosilane (TMSCl)

Indexed keywords

2 AMINOPYRAZINE; 3,4,5,6 TETRAHYDROPYRAZIN 2 AMINE DERIVATIVE; CARBONYL DERIVATIVE; CHLOROTRIMETHYLSILANE; CYANIDE; ETHYLENEDIAMINE DERIVATIVE; FUNCTIONAL GROUP; ISOCYANIDE; MOLECULAR SCAFFOLD; PYRAZINE DERIVATIVE; SPIROCYCLIC COMPOUND; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL REACTION; CHEMICAL STRUCTURE; MULTICOMPONENT REACTION; RING OPENING; SUBSTITUTION REACTION; SYNTHESIS; TECHNIQUE;

EID: 34547673707     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tetlet.2007.07.044     Document Type: Article

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