Regioselective two step synthesis of 3-substituted 2-aminoimidazo[1,2-a]pyrimidines

Tetrahedron Letters

Volumn 48, Issue 11, 2007, Pages 2041-2045

  Carballares, Santiago ^a   Cifuentes, Marta M ^a   Stephenson, Gregory A ^b  

^a ELI LILLY AND COMPANY   (Spain)

^b ELI LILLY AND COMPANY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PYRIMIDINE DERIVATIVE;

ARTICLE; CHEMICAL REACTION KINETICS; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; ISOMER; QUANTITATIVE ANALYSIS; STEREOCHEMISTRY; SUBSTITUTION REACTION; X RAY ANALYSIS;

EID: 33846897166     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tetlet.2006.11.181     Document Type: Article

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47. 6, 300 MHz) δ 8.65 (dd, J = 2.0, 7.0 Hz, 1H), 8.19 (dd, J = 1.8, 4.3 Hz, 1H), 7.62-7.18 (m, 10H), 6.88 (dd, J = 4.4, 11.1 Hz, 1H), 6.57 (t, J = 6.41 Hz, 1H), 4.57 (d, J = 4.5 Hz, 2H) ppm.