Chemokine production and chemokine receptor expression by human glioma cells: Role of CXCL10 in tumour cell proliferation

Journal of Neuroimmunology

Volumn 199, Issue 1-2, 2008, Pages 35-45

  Maru, Seema V ^a   Holloway, Karen A ^a   Flynn, Geraldine ^a   Lancashire, Christine L ^a   Loughlin, A Jane ^a   Male, David K ^a   Romero, Ignacio A ^a  

^a OPEN UNIVERSITY   (United Kingdom)

Author keywords

Chemokines; CXCL10; ERK; Glioma; Proliferation

Indexed keywords

CHEMOKINE; CHEMOKINE RECEPTOR; CHEMOKINE RECEPTOR CCR4; CHEMOKINE RECEPTOR CXCR1; CHEMOKINE RECEPTOR CXCR3; CHEMOKINE RECEPTOR CXCR4; GAMMA INTERFERON INDUCIBLE PROTEIN 10; INTERLEUKIN 8; MACROPHAGE DERIVED CHEMOKINE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MONOCYTE CHEMOTACTIC PROTEIN 1; RANTES; THYMIDINE; TRITIUM;

ARTICLE; ASTROCYTE; ASTROCYTOMA; ASTROCYTOMA CELL; CARCINOGENESIS; CELL PROLIFERATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; GLIOBLASTOMA; GLIOMA CELL; HUMAN; HUMAN CELL; HUMAN TISSUE; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ASTROCYTES; BLOTTING, WESTERN; CELL LINE, TUMOR; CELL PROLIFERATION; CHEMOKINE CXCL10; CHEMOKINES; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ENZYME-LINKED IMMUNOSORBENT ASSAY; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FLOW CYTOMETRY; GENE EXPRESSION; GLIOMA; HUMANS; RECEPTORS, CHEMOKINE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER;

EID: 47549093123     PISSN: 01655728     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jneuroim.2008.04.029     Document Type: Article

References (48)

1. Aksoy M.O., Yang Y., Ji R., Reddy P.J., Shahabuddin S., Litvin J., Rogers T.J., and Kelsen S.G. CXCR3 surface expression in human airway epithelial cells: cell cycle dependence and effect on cell proliferation. Am. J. Physiol., Lung Cell. Mol. Physiol. 290 5 (2006) L909-L918
2. Asensio V.C., and Campbell I.L. Chemokines in the CNS: plurifunctional mediators in diverse states. Trends Neurosci. 22 11 (1999) 504-512
3. Bacon K.B., and Harrison J.K. Chemokines and their receptors in neurobiology: perspectives in physiology and homeostasis. J. Neuroimmunol. 104 (2000) 92-97
4. Baeza N., Weller M., Yonekawa Y., Kleihues P., and Ohgaki H. PTEN methylation and expression in glioblastomas. Acta Neuropathol. (Berl) 106 5 (2003) 479-485
5. Bajetto A., Bonavia R., Barbero S., and Schettini G. Characterization of chemokines and their receptors in the central nervous system: physiopathological implications. J. Neurochem. 82 6 (2002) 1311-1329
6. Bajetto A., Barbieri F., Dorcaratto A., Barbero S., Daga A., Porcile C., Ravetti J.L., Zona G., Spaziante R., Corte G., et al. Expression of CXC chemokine receptors 1-5 and their ligands in human glioma tissues: role of CXCR4 and SDF1 in glioma cell proliferation and migration. Neurochem. Int. 49 5 (2006) 423-432
7. Barbero S., Bonavia R., Bajetto A., Porcile C., Pirani P., Ravetti J.L., Zona G.L., Spaziante R., Florio T., and Schettini G. Stromal cell-derived factor 1alpha stimulates human glioblastoma cell growth through the activation of both extracellular signal-regulated kinases 1/2 and Akt. Cancer Res. 63 8 (2003) 1969-1974
8. Barnes D., Huston M., Holmes R., beneniste E., Yong V., Scholz P., and Perez H. Induction of RANTES expression by astrocytes and astrocytoma cell lines. J. Neuroimmunol. 71 (1996) 207-214
9. Bertolini F., Dell'Agnola C., Mancuso P., Rabascio C., Burlini A., Monestiroli S., Gobbi A., Pruneri G., and Martinelli G. CXCR4 neutralization, a novel therapeutic approach for non-Hodgkin's lymphoma. Cancer Res. 62 11 (2002) 3106-3112
10. Bonacchi A., Romagnani P., Romanelli R., Efsen E., Annunziato F., Lasagni L., Francalanci M., Serio M., Laffi G., Pinzani M., et al. Signal transduction by the chemokine receptor CXCR3. J. Biol. Chem. 13 (2001) 9945-9954
11. Bonavia R., Bajetto A., Barbero S., Pirani P., Florio T., and Schettini G. Chemokines and their receptors in the CNS: expression of CXCL12/SDF-1 and CXCR4 and their role in astrocyte proliferation. Toxicol. Lett. 139 2-3 (2003) 181-189
12. Brat D.J., Bellail A.C., and Van Meir E.G. The role of interleukin-8 and its receptors in gliomagenesis and tumoral angiogenesis. Neuro-oncology 7 2 (2005) 122-133
13. Cazaubon S., Chaverot N., Romero I.A., Girault J.A., Adamson P., Strosberg A.D., and Couraud P.O. Growth factor activity of endothelin-1 in primary astrocytes mediated by adhesion-dependent and -independent pathways. J. Neurosci. 17 16 (1997) 6203-6212
14. Choi C., Xu X., Oh J.W., Lee S.J., Gillespie G.Y., Park H., Jo H., and Benveniste E.N. Fas-induced expression of chemokines in human glioma cells: involvement of extracellular signal-regulated kinase 1/2 and p38 mitogen-activated protein kinase. Cancer Res. 61 7 (2001) 3084-3091
15. Curiel T.J., Coukos G., Zou L., Alvarez X., Cheng P., Mottram P., Evdemon-Hogan M., Conejo-Garcia J.R., Zhang L., Burow M., et al. Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival. Nat. Med. 10 9 (2004) 942-949
16. Desbaillets I., Diserens A., de Tribolet N., Hamou M., and Van Meir E. Upregulation of Interleukin 8 by oxygen-deprived cells in glioblastoma suggests a role in leukocyte activation, chemotaxis and angiogenesis. J. Exp. Med. 186 8 (1997) 1201-1212
17. Ehtesham M., Winston J.A., Kabos P., and Thompson R.C. CXCR4 expression mediates glioma cell invasiveness. Oncogene 25 19 (2006) 2801-2806
18. Feldman E.D., Weinreich D.M., Carroll N.M., Burness M.L., Feldman A.L., Turner E., Xu H., and Alexander Jr. H.R. Interferon gamma-inducible protein 10 selectively inhibits proliferation and induces apoptosis in endothelial cells. Ann. Surg. Oncol. 13 1 (2006) 125-133
19. Floridi F., Trettel F., Di Bartolomeo S., Ciotti M., and Limatola C. Signalling pathways involved in the chemotactic activity of CXCL12 in cultured rat cerebellar neurons and CHP100 neuroepithelioma cells. J. Neuroimmunol. 135 1-2 (2003) 38-46
20. Flynn G., Maru S., Loughlin J., Romero I.A., and Male D. Regulation of chemokine receptor expression in human microglia and astrocytes. J. Neuroimmunol. 136 1-2 (2003) 84-93
21. Hall J.M., and Korach K.S. Stromal cell-derived factor 1, a novel target of estrogen receptor action, mediates the mitogenic effects of estradiol in ovarian and breast cancer cells. Mol. Endocrinol. 17 5 (2003) 792-803
22. Helbig G., Christopherson II K.W., Bhat-Nakshatri P., Kumar S., Kishimoto H., Miller K.D., Broxmeyer H.E., and Nakshatri H. NF-kappaB promotes breast cancer cell migration and metastasis by inducing the expression of the chemokine receptor CXCR4. J. Biol. Chem. 278 24 (2003) 21631-21638
23. Ishii N., Tada M., Sakuma S., Sawamura Y., Shinohe Y., and Abe H. Human astrocytoma cells are capable of producing macrophage inflammatory protein-1. J. Neuro-Oncol. 37 (1998) 17-23
24. Kleihues P., Soylemezoglu F., Schauble B., Scheithauer B.W., and Burger P.C. Histopathology, classification, and grading of gliomas. Glia 15 3 (1995) 211-221
25. Koshiba T., Hosotani R., Miyamoto Y., Ida J., Tsuji S., Nakajima S., Kawaguchi M., Kobayashi H., Doi R., Hori T., et al. Expression of stromal cell-derived factor 1 and CXCR4 ligand receptor system in pancreatic cancer: a possible role for tumor progression. Clin. Cancer Res. 6 9 (2000) 3530-3535
26. Lasagni L., Francalanci M., Annunziato F., Lazzeri E., Giannini S., Cosmi L., Sagrinati C., Mazzinghi B., Orlando C., Maggi E., et al. An alternatively spliced variant of CXCR3 mediates the inhibition of endothelial cell growth induced by IP-10, Mig, and I-TAC, and acts as functional receptor for platelet factor 4. J. Exp. Med. 197 11 (2003) 1537-1549
27. Li A., Varney M.L., and Singh R.K. Expression of interleukin 8 and its receptors in human colon carcinoma cells with different metastatic potentials. Clin. Cancer Res. 7 10 (2001) 3298-3304
28. Luan J., Shattuck-Brandt R., Haghnegahdar H., Owen J.D., Strieter R., Burdick M., Nirodi C., Beauchamp D., Johnson K.N., and Richmond A. Mechanism and biological significance of constitutive expression of MGSA/GRO chemokines in malignant melanoma tumor progression. J. Leukoc. Biol. 62 5 (1997) 588-597
29. Ma D., Nutt C.L., Shanehsaz P., Peng X., Louis D.N., and Kaetzel D.M. Autocrine platelet-derived growth factor-dependent gene expression in glioblastoma cells is mediated largely by activation of the transcription factor sterol regulatory element binding protein and is associated with altered genotype and patient survival in human brain tumors. Cancer Res. 65 13 (2005) 5523-5534
30. Mahajan S.D., Schwartz S.A., Shanahan T.C., Chawda R.P., and Nair M.P. Morphine regulates gene expression of alpha- and beta-chemokines and their receptors on astroglial cells via the opioid mu receptor. J. Immunol. 169 7 (2002) 3589-3599
31. Marjon P.L., Bobrovnikova-Marjon E.V., and Abcouwer S.F. Expression of the pro-angiogenic factors vascular endothelial growth factor and interleukin-8/CXCL8 by human breast carcinomas is responsive to nutrient deprivation and endoplasmic reticulum stress. Mol. Cancer. 3 1 (2004) 4
32. Milliken D., Scotton C., Raju S., Balkwill F., and Wilson J. Analysis of chemokines and chemokine receptor expression in ovarian cancer ascites. Clin. Cancer Res. 8 4 (2002) 1108-1114
33. Nishie A., Ono M., Shono T., Fukushi J., Otsubo M., Onoue H., Ito Y., Inamura T., Ikezaki K., Fukui M., et al. Macrophage infiltration and heme oxygenase-1 expression correlate with angiogenesis in human gliomas. Clin. Cancer Res. 5 5 (1999) 1107-1113
34. Oh J.W., Drabik K., Kutsch O., Choi C., Tousson A., and Benveniste E.N. CXC chemokine receptor 4 expression and function in human astroglioma cells. J. Immunol. (Baltimore, Md: 1950) 166 4 (2001) 2695-2704
35. Ohgaki H. Genetic pathways to glioblastomas. Neuropathology 25 1 (2005) 1-7
36. Payne A.S., and Cornelius L.A. The role of chemokines in melanoma tumor growth and metastasis. J. Invest. Dermatol. 118 6 (2002) 915-922
37. Reardon D.A., Rich J.N., Friedman H.S., and Bigner D.D. Recent advances in the treatment of malignant astrocytoma. J. Clin. Oncol. 24 8 (2006) 1253-1265
38. Rubin J.B., Kung A.L., Klein R.S., Chan J.A., Sun Y., Schmidt K., Kieran M.W., Luster A.D., and Segal R.A. A small-molecule antagonist of CXCR4 inhibits intracranial growth of primary brain tumors. Proc. Natl. Acad. Sci. U. S. A. 100 23 (2003) 13513-13518
39. Schuller U., Koch A., Hartmann W., Garre M.L., Goodyer C.G., Cama A., Sorensen N., Wiestler O.D., and Pietsch T. Subtype-specific expression and genetic alterations of the chemokine receptor gene CXCR4 in medulloblastomas. Int. J. Cancer. 117 1 (2005) 82-89
40. Sehgal A., Keener C., Boynton A.L., Warrick J., and Murphy G.P. CXCR-4, a chemokine receptor, is overexpressed in and required for proliferation of glioblastoma tumor cells. J. Surg. Oncol. 69 2 (1998) 99-104
41. Stark A.M., Witzel P., Strege R.J., Hugo H.H., and Mehdorn H.M. p53, mdm2, EGFR, and msh2 expression in paired initial and recurrent glioblastoma multiforme. J. Neurol. Neurosurg. Psychiatry 74 6 (2003) 779-783
42. Vicari A.P., and Caux C. Chemokines in cancer. Cytokine Growth Factor Rev. 13 143-154 (2002)
43. Wornle M., Schmid H., Merkle M., and Banas B. Effects of chemokines on proliferation and apoptosis of human mesangial cells. BMC Nephrol. 5 (2004) 8
44. Xia M., Bacskai B., Knowles R., Qin S., and Hyman B. Expression of the chemokine receptor CXCR3 on neurons and the elevated expression of its ligand in reactive astrocytes: in vitro ERK1/2 activation and role in Alzheimer's disease. J. Neuroimmun. 108 (2000) 227-235
45. Yang S.X., Chen J.H., Jiang X.F., Wang Q.L., Chen Z.Q., Zhao W., Feng Y.H., Xin R., Shi J.Q., and Bian X.W. Activation of chemokine receptor CXCR4 in malignant glioma cells promotes the production of vascular endothelial growth factor. Biochem. Biophys. Res. Commun. 335 2 (2005) 523-528
46. Zeelenberg I.S., Ruuls-Van Stalle L., and Roos E. The chemokine receptor CXCR4 is required for outgrowth of colon carcinoma micrometastases. Cancer Res. 63 13 (2003) 3833-3839
47. Zhang J., Sarkar S., and Yong V.W. The chemokine stromal cell derived factor-1 (CXCL12) promotes glioma invasiveness through MT2-matrix metalloproteinase. Carcinogenesis 26 12 (2005) 2069-2077
48. Zhou Y., Larsen P.H., Hao C., and Yong V.W. CXCR4 is a major chemokine receptor on glioma cells and mediates their survival. J. Biol. Chem. 277 51 (2002) 49481-49487