Differential analysis of CD4+ Th memory clones with identical T-cell receptor (TCR)-αβ rearrangement (non-transgenic), but distinct lymphokine phenotype, reveals diverse and novel gene expression

Immunology

Volumn 113, Issue 2, 2004, Pages 194-202

  Graham, Christine M ^a   Thomas, D Brian ^a  

^a NATIONAL INSTITUTE FOR MEDICAL RESEARCH   (United Kingdom)

Author keywords

Cytokines; Murine; T lymphocytes; Transcriptional profiling

Indexed keywords

CD94 ANTIGEN; CELL RECEPTOR; COMPLEMENTARY DNA; GAMMA INTERFERON; GRANZYME A; GRANZYME B; GRANZYME C; GRANZYME G; INTERLEUKIN 10; INTERLEUKIN 4; INTERLEUKIN 5; LYMPHOKINE; MEMBRANE PROTEIN; NATURAL KILLER CELL RECEPTOR NKG2A; PHOSPHOPROTEIN PHOSPHATASE; PROTEIN KINASE; T LYMPHOCYTE RECEPTOR; T LYMPHOCYTE RECEPTOR ALPHA CHAIN; T LYMPHOCYTE RECEPTOR BETA CHAIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; DNA SEQUENCE; GENE EXPRESSION; GENE IDENTIFICATION; GENE MAPPING; GENETIC TRANSCRIPTION; GENOME; MEMORY CELL; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PHENOTYPE; PRIORITY JOURNAL; RNA BINDING; SUBTRACTIVE HYBRIDIZATION; T LYMPHOCYTE; UNINDEXED SEQUENCE; VIRUS INFECTION;

ANIMALS; CD4-POSITIVE T-LYMPHOCYTES; CLONING, MOLECULAR; CYTOKINES; DNA; GENE EXPRESSION REGULATION; GENE REARRANGEMENT, ALPHA-CHAIN T-CELL ANTIGEN RECEPTOR; IMMUNOLOGIC MEMORY; INTERFERON TYPE II; INTERLEUKIN-10; INTERLEUKIN-4; INTERLEUKIN-5; MICE; MICE, INBRED C57BL; PHENOTYPE; RECEPTORS, ANTIGEN, T-CELL, ALPHA-BETA; SIGNAL TRANSDUCTION; T-LYMPHOCYTES, HELPER-INDUCER; TISSUE DISTRIBUTION; TRANSCRIPTION, GENETIC;

EID: 4744365527     PISSN: 00192805     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1365-2567.2004.01953.x     Document Type: Article

References (56)

1. Mossmann TR, Cherwinski H, Bond MW, Giedlin MA, Coffman RL. Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins. J Immunol 1986; 136:2348-57.
2. Zheng W, Flavell RA. The transcription factor GATA-3 is necessary and sufficient for Th2 cytokine gene expression in CD4 T cells. Cell 1997; 89:587-96.
3. Szabo SJ, Kim ST, Costa GL et al. A novel transcription factor T-bet, directs Th1 lineage and commitment. Cell 2000; 100:655-69.
4. Robinson DS, O'Garra A. Further checkpoints in Th1 development. Immunity 2002; 16:755-8.
5. Grogan JL, Locksley R. MT helper cell differentiation. On again, off again. Curr Opin Immunol 2002; 14:366-72.
6. Glimcher LH, Murphy KM. Lineage commitment in the immune system: the T helper lymphocyte grows up. Genes Dev 2000; 14:1693-711.
7. Graham CM, Smith CA, Thomas DB. Novel diversity in Th1, Th2 type differentiation of hemagglutinin-specific T cell clones elicited by natural influenza virus infection in three major haplotypes (H-2b,d,k). J Immunol 1998; 161:1094-103.
8. + T cell can give rise to progeny expressing type 1 and/or type 2 cytokine genes and can retain multipotentiality through many cell divisions. Proc Natl Acad Sci USA 1997; 94:8070-5.
9. 2 zinc finger proteins. Annu Rev Biochem 2001; 70:313-40.
10. Rasmussen UB, Wolf C, Mattie M-G et al. Identification of a new interferon-α-inducible gene (p27) on human chromosome 14q32 and its expression in breast carcinoma. Cancer Res 1993; 53:4096-101.
11. Jeffers M, Paciucci R, Pellicer A. Characterization of unr; a gene closely linked to N-ras. Nucl Acids Res 1990; 18:4891-9.
12. Mitchell SA, Spriggs KA, Coldwell MJ, Jackson RJ, Willis AE. The Apaf-1 internal ribosome entry segment attains the correct structural conformation for function via interactions with PTB and unr. Mol Cell 2003; 11:757-71.
13. Boussadia O, Niepmann M, Creancier I et al. Unr is required in vivo for efficient initiation of translation from the internal ribosome entry sites of both rhinovirus and poliovirus. J Virol 2003; 77:3353-9.
14. Chan SY, Chan AK, Cheung BP, Liang Y, Leung MP. Identification of genes expressed during myocardial development. Chin Med J (Engl) 2003; 116:1129-332.
15. Sun CT, Lo WY, Wang IH et al. Transcriptional repression of human hepatitis B virus genes by negative regulatory element-binding protein/SON. J Biol Chem 2001; 276:24059-67.
16. Chiesa MD, Vitale M, Carlomagno S et al. The natural killer cell-mediated killing of autologous dendritic cells is confined to a cell subset expressing CD94/NKG2A, but lacking inhibitory killer Ig-like receptors. Eur J Immunol 2003; 33:1657-66.
17. Raulet D. H Roles of the NKG2D immunoreceptor and its ligands. Nat Rev Immunol 2003; 3:781-90.
18. Konstantina E, Taner SB, Önfelt B et al. Cell surface organization of stress-inducible proteins ULBP and MICA that stimulate human NK cells and T cells via NKG2D. J Exp Med 2004; 199:1005-10.
19. + T cells in response to CD3-mediated stimulation. J Leukoc Biol 2001; 70:219-24.
20. Zingoni A, Palmieri G, Morrone S et al. CD69-triggered ERK activation and functions are negatively regulated by CD94/NKG2-A inhibitory receptor. Eur J Immunol 2000; 30:644-51.
21. + T cell responses. Nature Immunol 2002; 3:189-95.
22. Hartt Meyers J, Ryu A, Monney L et al. CD94/NKG2 is expressed on Th1 but not Th2 cells and costimulates Th1 effector functions. J Immunol 2002; 169:5382-6.
23. Hamalainen H, Meissner S, Lahesmaa R. Signalling lymphocytic activation molecule (SLAM) is differentially expressed in human Th1 and Th2 cells. J Immunol Meth 2000; 242:9-19.
24. Kuchroo VK, Umetsu DT, DeKruyff RH, Freeman GJ. The TIM gene family, emerging roles in immunity and disease. Nat Rev Immunol 2003; 3:454-62.
25. Kam CM, Hudig D, Powers JC. Granzymes (lymphocyte serine proteases): characterization with natural and synthetic substrates and inhibitors. Biochim Biophys Acta 2000; 1477:307-23.
26. Rogge L, Bianchi E, Biffi M et al. Transcript imaging of the development of human T helper cells using oligonucleotide arrays. Nature Genet 2000; 25:96-101.
27. + type 1 and type 2 T cells. J Immunol 2001; 167:3057-63.
28. Sandler NG, Mentink-Kane MM, Cheever AW, Wynn TA. Global gene expression profiles during acute pathogen-induced pulmonary inflammation reveal divergent roles for Th1 and Th2 responses in tissue repair. J Immunol 2003; 171:3655-67.
29. Jiang Z, Johnson HJ, Nie H et al. Pellino 1 is required for interleukin-1 (IL-1)-mediated signaling through its interaction with the IL-1 receptor-associated kinase 4 (IRAK4)-IRAK-tumor necrosis factor receptor-associated factor 6 (TRAF6) complex. J Biol Chem 2003; 278:10952-6.
30. Rich T, Allen RL, Lucas A-M, Stewart A, Trowsdale J. Pellino-related sequences from Caenorhabditiis elegans and Homo sapiens. Immunogenetics 2000; 52:145-9.
31. Zilian O, Saner C, Hagedorn L et al. Multiple roles of mouse Numb in tuning developmental cell fates. Curr Biol 2001; 11:494-501.
32. Matsuda A, Suzuki Y, Honda G et al. Large-scale identification and characterization of human genes that activate NK-kappaB and MAPK signaling pathways. Oncogene 2003; 22:3307-18.
33. Mattison CP, Ota IM. Two tyrosine kinase phosphatases, Ptp2 and Ptp3, modulate the subcellular localization of the Hog1 MAP kinase in yeast. Genes Dev 2000; 14:1229-35.
34. Mustelin T, Brockdorff J, Rudbeck L et al. The next wave: protein tyrosine phosphatases enter T cell antigen receptor signalling. Cellular Signalling 1999; 11:637-50.
35. Ehrhardt A, Ehrhardt GRA, Guo X, Schrader JW. Ras and relatives - job sharing and networking keep an old family together. Exp Hematol 2002; 30:1089-106.
36. Reedquist KA, Bos JL. Costimulation through CD28 suppresses T cell receptor-dependent activation of the Ras-like small GTPase Rap1 in human T lymphocytes. J Biol Chem 1998; 273:4944-9.
37. Altman A, Deckert M. The function of small GTPases in signaling by immune recognition and other leukocyte receptors. Adv Immunol 1999; 72:1-101.
38. Cantrell DA. GTPases and T cell activation. Immunol Rev 2003; 192:122-30.
39. Kawane T, Mimura J, Fujii-Kuriyama Y, Horiuchi N. Parathyroid hormone (PTH) suppresses rat PTH/PTH-related protein receptor gene promoter. Biochem Biophys Res Commun 2001; 287:313-22.
40. Recalcat IS, Taramelli D, Conte D, Cairo G. Nitric oxide-mediated induction of ferritin synthesis in J774 macrophages by inflammatory cytokines: role of selective iron regulatory protein-2 degradation. Blood 1998; 91:1059-66.
41. Flood-Page P, Menzies-Gow A, Phipps S et al. Anti-IL-5 treatment reduces deposition of ECM proteins in the bronchial subepithelial basement membrane of mild atopic asthmatics. J Clin Invest 2003; 112:1029-36.
42. Yoshioka N, Inoue H, Nakanishi K et al. Isolation of transformation suppressor genes by cDNA subtraction, lumican suppresses transformation induced by v-src and v-K-ras. J Virol 2001; 74:1008-13.
43. Tai SK, Tan OJ, Chow VT et al. Differential expression of metallothionein 1 and 2 isoforms in breast cancer lines with different invasive potential: identification of a novel nonsilent metallothionein-1H mutant variant. Am J Pathol 2003; 163:2009-19.
44. Wellner M, Herse F, Janke J et al. Endothelial cell specific molecule-1 - a newly identified protein in adipocytes. Horm Metab Res 2003; 35:217-21.
45. 2+-binding proteins localised to the secretory pathway of mammalian cells. FEBS Lett 2000; 244:11-8.
46. Fu J, Pirozzi G, Sanjay A et al. Localization of ribophorin II to the endoplasmic reticulum involves both its transmembrane and cytoplasmic domains. Eur J Cell Biol 2003; 79:219-28.
47. Hufton SE, Muerkerk PT, Brandwijk R et al. A profile of differentially expressed genes in primary colorectal cancer using suppression subtractive hybridization. FEBS Lett 1999; 263:77-82.
48. Kosak CA, Su Y, Raj NB, Pitha PM. Identification and genetic mapping of differentially expressed genes in mice differing at the If1 interferon regulatory locus. Mamm Genome 1999; 10: 853-7.
49. Chen FW, Ioannou YA. Ribosomal proteins in cell proliferation and apoptosis. Int Rev Immunol 1999; 18:429-48.
50. Mazumder B, Sampath P, Seshadri V et al. Regulated release of L13a from the 60S ribosomal subunit as a mechanism of transcript-specific translational control. Cell 2003; 115:187-96.
51. Postberg J, Juranek SA, Feller S et al. Association of the telomere-telomere-binding protein complex of hypotrichous ciliates with the nuclear matrix and dissociation during replication. J Cell Sci 2001; 114:1861-6.
52. Péterfly M, Phan J, Oswell GM et al. Genetic, physical, and transcript map of the fld region on mouse chromosome 12. Genomics 1999; 62:436-44.
53. Kültz D. Phylogenetic and functional classification of mitogen-and stress-activated protein kinases. J Mol Evol 1998; 46: 571-88.
54. Takazoe K, Foti R, Tesch L et al. Up-regulation of the tumour-associated marker CD44V6 in experimental kidney disease. Clin Exp Immunol 2000; 121:523-32.
55. Reimer RJ, Edwards RH. Organic anion transport is the primary function of the SLC17/type I phosphate transporter family. Eur J Physiol 2004; 447:629.
56. Hershko A, Ciechanover A. The ubiquitin system. Annu Rev Biochem 1998; 67:425-35.