Differential in vitro neurotoxicity of the flame retardant PBDE-99 and of the PCB Aroclor 1254 in human astrocytoma cells

Toxicology Letters

Volumn 154, Issue 1-2, 2004, Pages 11-21

  Madia, Federica ^a   Giordano, Gennaro ^a   Fattori, Vittorio ^a   Vitalone, Annabella ^b   Branchi, Igor ^c   Capone, Francesca ^c   Costa, Lucio G ^b,d  

^a SAPIENZA UNIVERSITY OF ROME   (Italy)

^b UNIVERSITY OF BARI   (Italy)

^c ISTITUTO SUPERIORE DI SANITÀ   (Italy)

^d UNIVERSITY OF WASHINGTON   (United States)

Author keywords

Aroclor 1254; Brominated flame retardants; Human astrocytoma cells; Neurotoxicity; PBDE 99

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 2 [1 (3 DIMETHYLAMINOPROPYL) 3 INDOLYL] 3 (3 INDOLYL)MALEIMIDE; 2,2',4,4',5 PENTABROMODIPHENYL ETHER; 3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; 4 [5 (4 METHYL 1 PIPERAZINYL)[2,5' BI 1H BENZIMIDAZOL] 2' YL]PHENOL; AROCLOR 1254; DIPHENYL ETHER DERIVATIVE; GENISTEIN; LACTATE DEHYDROGENASE; MITOGEN ACTIVATED PROTEIN KINASE KINASE; PHORBOL ESTER; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; POLYCHLORINATED BIPHENYL DERIVATIVE; PROTEIN KINASE C ALPHA; PROTEIN KINASE C EPSILON; PROTEIN KINASE C GAMMA; PROTEIN KINASE C INHIBITOR; PROTEIN TYROSINE KINASE INHIBITOR; TRYPAN BLUE; UNCLASSIFIED DRUG;

ARTICLE; ASTROCYTE; ASTROCYTOMA CELL; CELL DEATH; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOWN REGULATION; ENZYME RELEASE; HUMAN; HUMAN CELL; NEUROTOXICITY; NICK END LABELING; PRIORITY JOURNAL; PROTEIN TRANSPORT; STAINING;

APOPTOSIS; AROCLOR 1254; ASTROCYTES; ASTROCYTOMA; CELL LINE, TUMOR; CELL SURVIVAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DOWN-REGULATION; ENZYME INHIBITORS; FLAME RETARDANTS; FORMAZANS; HUMANS; INDOLES; ISOENZYMES; L-LACTATE DEHYDROGENASE; MALEIMIDES; PHENYL ETHERS; PROTEIN KINASE C; TETRADECANOYLPHORBOL ACETATE; TETRAZOLIUM SALTS; TRYPAN BLUE; TUMOR SUPPRESSOR PROTEIN P53;

EID: 4744361046     PISSN: 03784274     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.toxlet.2004.06.013     Document Type: Article

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