Phosphorylation of the platelet-derived growth factor receptor-β by G protein-coupled receptor kinase-2 reduces receptor signaling and interaction with the Na+/H+ exchanger regulatory factor

Journal of Biological Chemistry

Volumn 279, Issue 40, 2004, Pages 41775-41782

  Hildreth, Kerry L ^a   Wu, Jiao Hui ^a   Barak, Larry S ^a   Exum, Sabrina T ^a   Kim, Luke K ^a   Peppel, Karsten ^a   Freedman, Neil J ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; DIMERIZATION; DISSOCIATION; GROWTH KINETICS; MUTAGENESIS; PHYSIOLOGY; PROTEINS; REACTION KINETICS; SIGNALING;

CELLULAR SYSTEMS; EPIDERMAL GROWTH FACTOR RECEPTORS (EGFR); GROWTH FACTORS; PHOSPHORYLATION;

ENZYME KINETICS;

EPIDERMAL GROWTH FACTOR RECEPTOR; G PROTEIN COUPLED RECEPTOR KINASE 2; PHOSPHATIDYLINOSITIDE; PLATELET DERIVED GROWTH FACTOR BETA RECEPTOR; PROTEIN KINASE B; SERINE; SODIUM PROTON EXCHANGE PROTEIN; SODIUM PROTON EXCHANGE PROTEIN REGULATORY FACTOR; TYROSINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL MUTANT; CONTROLLED STUDY; DESENSITIZATION; DIMERIZATION; FIBROBLAST CULTURE; GENE ACTIVATION; GENE EXPRESSION; GENE OVEREXPRESSION; KNOCKOUT GENE; MOUSE; MUTATION; NONHUMAN; PHOSPHOINOSITIDE METABOLISM; PHOSPHORYLATION; PRIORITY JOURNAL; PROTEIN INTERACTION; SIGNAL DETECTION; SIGNAL TRANSDUCTION; WILD TYPE;

ANIMALS; BETA-ADRENERGIC RECEPTOR KINASE; CATTLE; CELL LINE; CYCLIC AMP-DEPENDENT PROTEIN KINASES; EPIDERMAL GROWTH FACTOR; FIBROBLASTS; HUMANS; MICE; PHOSPHOPROTEINS; PHOSPHORYLATION; PROTEIN BINDING; RECEPTOR, PLATELET-DERIVED GROWTH FACTOR BETA; SERINE; SIGNAL TRANSDUCTION; SODIUM-HYDROGEN ANTIPORTER; TRANSFECTION;

ANIMALIA;

EID: 4744349417     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M403274200     Document Type: Article

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