Occurrence of ochratoxin A in cocoa products and chocolate

Journal of Agricultural and Food Chemistry

Volumn 52, Issue 20, 2004, Pages 6347-6352

  Bonvehí, Josep Serra ^a  

^a Nederland Company   (Spain)

Author keywords

Chocolate; Cocoa; Incidences; Ochratoxin; Quality

Indexed keywords

OCHRATOXIN;

ARTICLE; CACAO; DIET; FOOD COMPOSITION; FOOD CONTAMINATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IMMUNOAFFINITY CHROMATOGRAPHY; POWDER;

ANIMALS; CACAO; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; FOOD CONTAMINATION; MYCOTOXINS; OCHRATOXINS; SWINE;

PHASEOLUS (ANGIOSPERM); THEOBROMA CACAO;

EID: 4744338765     PISSN: 00218561     EISSN: None     Source Type: Journal    
DOI: 10.1021/jf040153w     Document Type: Article

References (36)

1. Aydin, G.; Ozcelik, N.; Cicek, E.; Soyoz, M. Histopathologic changes in liver and renal tissues by ochratoxin A and melatonin in rats. Hum. Exp. Toxicol. 2003, 22, 383-391.
2. Moss, M. O. Mode of formation of ochratoxin A. Food Addit. Contam. 1996, 13 (Suppl.), 5-9.
3. International Agency for Research on Cancer (IARC). IARC Monographs on the Evaluation of Carcinogenic Risks to Humans; IARC Working Group, World Health Organization: Lyon, France, 1993; Vol. 56.
4. Burdaspal, P. A.; Legarda, T. M. Ochratoxin A in samples of different types of chocolate and cacao powder, marketed in Spain and fifteen foreign countries. Alimentaria 2003, 40, 143-153.
5. Drusch, S.; Ragab, W. Mycotoxins in fruits, fruit juices, and dried fruits. J. Food Prot. 2003, 66, 1514-1527.
6. Engel, G. Ochratoxin A in sweets, oil sweets and dairy products. Arch. Lebensmittelhyg. 2000, 51, 98-101.
7. Zimmerli, B.; Dick, R. Determination of ochratoxin A at the ppt level in human blood, serum, milk and some foodstuffs by high-performance liquid chromatography with enhanced fluorescence detection and immunoaffinity column cleanup: Methodology and Swiss data. J. Chromatogr. B 1995, 666, 85-99.
8. Ueno, Y. Residue and risk of ochratoxin A in human plasma and beverages in Japan. Mycotoxins 1998, 47, 25-32.
9. Studer-Rohr, I.; Dietrich, D. R.; Schlatter, J.; Schlatter, C. H. Ochratoxin A in Humans: Exposure, Kinetics and Risk Assessment. Dissertation 11071 of the Swis Federal Institute of Technology (ETH), Zürich, 1995.
10. Romani, S.; Pinnavaia, G. G.; Rosa, M. D. Influence of roasting levels on ochratoxin A content in coffee. J. Agric. Food Chem. 2003, 51, 5168-5171.
11. Bucheli, P.; Meyer, I.; Pittet, A.; Vuataz, G.; Viani, R. Industrial storage of green Robusta coffee under tropical conditions and its impact on raw material quality and ochratoxin A content. J. Agric. Food Chem. 1998, 46, 4507-4511.
12. Bucheli, P.; Kanchanomai, C.; Meyer, I.; Pittet, A. Development of ochratoxin A during Robusta (Coffea canephora) coffee cherry drying. J. Agric. Food Chem. 2000, 48, 1358-1362.
13. Batista, L. R.; Chalfoun, S. M.; Prado, G.; Schwan, R. F.; Wheals, A. E. Toxigenic fungi associated with processed (green) beans (Coffea arabica L.). Int. J. Food Microbiol. 2003, 85, 293-300.
14. Serra Bonvehí, J.; Ventura Coll, F. Factors affecting the formation of alkylpyrazines during roasting treatment in natural and alkalinized cocoa powder. J. Agric. Food Chem. 2002, 50, 3743-3750.
15. Park, D. L. Perspectives on mycotoxin decontamination procedures. Food Addit. Contam. 1993, 10, 49-60.
16. Van Egmond, H. P. Worldwide regulations for ochratoxin A. IARC Sci. Publ. 1999, No. 115, 331-336.
17. World Health Organisation. Evaluation of Certain Food Additives and Contaminants. 44th Report of the Joint FAO/WHO Expert Committee on Food Additives; WHO Technical Report Series 859; WHO: Geneva, Switzerland, 1996.
18. Boorman, G. A. Toxicology and carcinogenesis studies of ochratoxin A in F344/N rats. NTP Technical Report NTP TR 358, 1989.
19. European Commission Scientific Committee for Food, DG XXIV, SCF. Opinion on Ochratoxin A, CS/CNTM/MYC/14, Sept 18, 1998.
20. European Union Commission. Regulation EC amending regulation (EC) 466/2001 setting maximum levels for certain contaminants in foodstuffs of March 12, 2002; No. 472/2002.
21. Working Document of the Expert Committee "Agricultural Contaminants" of the European Commision Scientific Commitee for Food. Council Meeting of Nov 18, 2003.
22. Hurst, W. J.; Synder, K. P.; Martin, R. A. High-performance liquid chromatographic determination of the mycotoxins patulin, penicillic acid, zearalenone and sterigmatocystin in artificially contaminated cocoa beans. J. Chromatogr. 1987, 392, 389-396.
23. Hurst, W. J.; Martin, R. A. High-performance liquid chromatographic determination of ochratoxin A in artificially contaminated cocoa beans using automated sample clean-up. J. Chromatogr. 1998, 10, 89-94.
24. Belli, N.; Marín, S.; Sanchis, V.; Ramos, A. J. Review: Ochratoxin A (OTA) in wines, musts and grape juices: occurrence, regulations and methods of analysis. Food Sci. Technol. 2002, 8, 325-335.
25. Vandeven, M.; Whitaker, Th.; Slate, A. Statistical approach for risk assessment of aflatoxin sampling plan used by manufacturers for raw shelled peanuts. J. AOAC Int. 2002, 85, 925-932.
26. Association of Official Analytical Chemists. In Official Methods of Analysis, 16th ed.; Williams, S., Ed.; AOAC: Arlington, VA, 1995; Chapter 49, pp 37-39.
27. Biopharm Rhône Ltd. Ochratoxin A extraction method. Application note for analysis of ochratoxin A in cocoa and cocoa shells using Ochraprep column. Ref. N: A6- P14.V3 and A13- P14.V2, Glasgow, U.K., 2001.
28. SAS. SAS User's Guide Statistics, version 6, 4th ed.; SAS Institute: Cary, NC, 1990.
29. Brittain, H. G. Validation of analytical methodology. J. Validation Technol. 1997, 3, 275-280.
30. Pittet, A.; Tornare, D.; Huggett, A.; Viani, R. Liquid chromatographic determination of ochratoxin A in pure and adulterated soluble coffee using an immunoaffinitty column cleanup procedure. J. Agric. Food Chem. 1996, 44, 3564-3569.
31. AOAC. Peer-Verified Methods Program. Manual on Policies and Procedures; AOAC International: Gaithersburg, MD, 1993.
32. Serra Bonvehí, J.; Aragay Benería, M. Composition of dietary fibre in cocoa husk. Z. Lebensm. Unters. Forsch. A 1998, 207, 105-109.
33. WHO. Toxicological Evaluation of Certain Food Additives and Contaminants; Prepared by the 37th Meeting of the Joint FAO/ WHO Expert Committee on Food Additives; WHO Food Additives Series 28; Geneva, Switzerland, 1991; pp 365-417.
34. Moolgavkar, S. H. Carcinogenesis models: an overview. Basic Life Sci. 1991, 58, 387-396.
35. Ministerio de Agricultura, Pesca y Alimentación. Dieta Alimentaria Española; edited for MAPA (Secretaría General Técnica): Madrid, Spain, 2000.
36. European Commission Scientific Committee for Food, SCOOP task 3.2.7. Reports on tasks for scientific cooperation: assessment of dietary intake of ochratoxin A by the population of EU Member States, 2002.