Permeation and metabolism of a novel ascorbic acid derivative, disodium isostearyl 2-O-L-ascorbyl phosphate, in human living skin equivalent models

Skin Pharmacology and Physiology

Volumn 21, Issue 4, 2008, Pages 235-243

  Shibayama, H ^a,b   Hisama, M ^b   Matsuda, S ^b   Ohtsuki, M ^a  

^a JICHI MEDICAL UNIVERSITY   (Japan)

^b Toyo Beauty Co Ltd   (Japan)

Author keywords

Amphiphilic vitamin C derivative; Disodium isostearyl 2 O L ascorbyl phosphate; Skin accumulation; Skin metabolite; Skin permeability

Indexed keywords

ASCORBIC ACID DERIVATIVE; DISODIUM ISOSTEARYL 2 O ASCORBYL PHOSPHATE; ESTERASE; PHOSPHATASE; SODIUM ASCORBIC ACID 2 PHOSPHATE;

ARTICLE; DIFFUSION; DRUG ACCUMULATION; DRUG HYDROLYSIS; DRUG METABOLISM; DRUG PENETRATION; DRUG STABILITY; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; PRIORITY JOURNAL; SKIN CARE;

ADMINISTRATION, CUTANEOUS; ASCORBIC ACID; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; HUMANS; MODELS, BIOLOGICAL; PRODRUGS; SKIN ABSORPTION; VITAMINS;

EID: 47249140317     PISSN: 16605527     EISSN: None     Source Type: Journal    
DOI: 10.1159/000139128     Document Type: Article

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